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Patients taking weight-loss drugs often make 5 critical mistakes, doctor warns

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Patients taking weight-loss drugs often make 5 critical mistakes, doctor warns

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GLP-1 drugs (glucagon-like peptide-1s) have exploded in popularity in recent years – initially as a way to control diabetes and then as tools for weight loss.

Growing research suggests that these drugs – which include semaglutide and tirzepatide – potentially have benefits beyond weight loss, with stronger evidence for cardiovascular and kidney health.

Even so, experts caution that these medications are not foolproof — and using them the wrong way can undermine results or even create new health problems.

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Dr. Meena T. Malhotra, MD, a functional medicine doctor and weight-loss specialist in a suburb of Chicago, confirmed that she has seen myriad health improvements in patients taking GLP-1s – particularly those with diabetes who were “very sick.”

Growing research suggests that GLP-1s potentially have benefits beyond weight loss, with stronger evidence for cardiovascular and kidney health. (iStock)

“We observed that this sick population was doing better than the diabetics who were on other diabetes medicines,” she shared with Fox News Digital, noting that she observed improvements in brain health, memory, heart health, circulation, and liver and kidney function. “We realized there was more to the drug than just sugar control and weight loss.”

Malhotra said she believes many people can safely microdose GLP-1s, but she cautions against the following common mistakes.

Mistake No. 1: Taking GLP-1s before making lifestyle changes

Anyone considering GLP-1s should first focus on adopting a healthy lifestyle, Malhotra emphasized – a view widely shared by endocrinologists and obesity medicine specialists.

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GLP-1 medications work by slowing gastric emptying, reducing appetite and improving insulin signaling. People with preexisting GI symptoms may be more prone to discomfort or intolerance, though responses vary, and formal evidence is limited.

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Before beginning the medication, Malhotra recommends improving basic nutritional habits, such as increasing intake of whole, minimally processed foods, and prioritizing protein and fiber to support satiety and gut health.

Even small improvements in diet can lead to early weight loss, reduced fluid retention and improvements in insulin sensitivity, doctors agree. (iStock)

Even small improvements can lead to early weight loss, reduced fluid retention and improvements in insulin sensitivity, doctors agree. 

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Once GLP-1 medications are started, these lifestyle modifications may reduce the necessary dose amount, result in fewer side effects and help preserve lean muscle mass.

Mistake No. 2: Starting without proper medical evaluation 

The growing trend of obtaining GLP-1 medications online without proper medical oversight can pose serious health risks, Malhotra warned.

“Nobody examines the patient – they just fill out a form and the medicine shows up at their door,” she said.

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Patients should see a medical provider for a thorough exam and blood work before starting the drugs, the doctor emphasized.

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“If something is off, it needs to be addressed,” she said. “Whether it’s a thyroid issue, a heart condition or another factor slowing your metabolism, any underlying problems should be fixed first.”

The growing trend of obtaining GLP-1 medications online without proper medical oversight can pose serious health risks, the doctor warned. (iStock)

During treatment, Malhotra recommends that her patients come in once a month to make sure they are losing fat and not lean muscle mass. “That’s very important, because if you lose lean mass, your body is not getting healthier,” she said.

This ongoing monitoring also helps to ensure that the patient is following a balanced diet, getting adequate protein and adhering to strength training. “There’s more to it than just giving yourself a shot,” Malhotra added.

Mistake No. 3: Not getting enough protein

One of the biggest mistakes people make when taking GLP-1s is cutting calories but not getting sufficient protein, according to Malhotra.

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“If you are decreasing the calories but not fixing the nutritional foundation, you will lose lean mass,” the doctor said. “But if you’re eating a balanced diet with adequate protein and doing strength training with a smaller dose of the drug, you will get better results and your health will improve.”

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Most people need about 0.5 to 0.8 grams of protein per pound of body weight each day to maintain muscle and support overall health, according to medical experts. For a 200-pound person, that would equate to roughly 100 to 160 grams of protein daily.

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Higher amounts may be needed for those who are physically active or trying to build strength. “The amount of protein you need will depend on the frequency and intensity of your workouts,” Malhotra said. 

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Mistake No. 4: Increasing doses too quickly

Another common mistake is rushing the process and increasing GLP-1 doses too quickly in hopes of faster results, according to the doctor.

“You may start to see results within the first week or month, but some people do need a higher dose over time,” she said. “The key is to be patient and increase it gradually — typically month by month.”

Another common mistake is rushing the process and increasing GLP-1 doses too quickly in hopes of faster results. (iStock)

If a patient doesn’t see results after the first injection, that doesn’t mean the dose should be doubled right away, according to Malhotra. 

“That’s a recipe for problems, including side effects like pancreatitis,” she said. “Your body needs time to adjust and adapt.”

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“You can go up if you hit a plateau or if it’s not helping, but we usually wait a month to increase the dose.”

While many expect “instant gratification,” health is about balance, Malhotra added. “It won’t take 20 years, but give it two months, I think that’s fair.”

A general rule of thumb, according to the doctor, is “don’t start too soon, don’t stop too soon.”

Mistake No. 5: Not managing side effects properly

GLP-1 side effects can often be prevented by building a strong foundation of health and keeping everything in balance, according to Malhotra. 

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“That said, some people will still have side effects, and there are ways to manage them,” she said.

“If you are decreasing the calories but not fixing the nutritional foundation, you will lose lean mass.”

The doctor recommends eating smaller, more frequent meals instead of large portions — ideally about the size of your fist. 

It’s also important to keep fat intake low, she advised – GLP-1 medications already slow stomach emptying and fat can slow it even further, which may worsen nausea.

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For nausea and constipation, simple strategies can go a long way, according to the doctor. Some patients find ginger helpful for nausea, she said, though it is not a substitute for medical guidance.

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Incorporating more liquids, such as shakes, soups and broths, can be easier on the stomach, she suggested. Prunes and other fiber-rich foods can help support digestion and prevent constipation.

“These little lifestyle hacks can help a lot with managing the side effects, instead of stopping and then finding that your weight is yo-yoing,” Malhotra said.

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Scientists unveil ‘living bandage’ that could dramatically speed wound healing

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Scientists unveil ‘living bandage’ that could dramatically speed wound healing

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A new “living bandage” could soon revolutionize how doctors treat serious injuries by accelerating the healing process, according to new research reported by SWNS.

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The high-tech patch was developed by researchers at Rice University in Texas. It acts like an around-the-clock mini factory, continuously delivering healing proteins directly to different types of wounds, the same source noted.

Caring for chronic wounds is often a challenge for doctors, as it’s difficult to deliver steady, localized signals that tell the body to repair its own tissue, the researchers said. 

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The body naturally relies on small chemical messengers called cytokines to control inflammation and healing. However, traditional treatments like ointments or injections usually fail, as fragile proteins break down too quickly or wash away from the injury site.

To solve the problem, the research team created a cell-based patch that stays on top of the wound. Inside the device, scientists placed engineered cells programmed to manufacture and secrete three specific healing cytokines, known as IL-10, IL-12 and Transforming Growth Factor-beta.

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A living bandage patch delivers healing proteins from engineered cells to accelerate wound healing, according to new research by American scientists. (Jared Jones/Rice University/SWNS)

These cells are safely housed inside protective material that acts like a shield — letting vital nutrients and therapeutic proteins pass through to the skin while keeping the body’s immune system from attacking the engineered cells inside.

The system also uses a special hydrogel that helps the patch blend naturally with the wound, SWNS reported. It may be updated eventually, the research team indicated, to work alongside electronic components.

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In lab tests on rodents and pigs, the patch successfully accelerated wound healing. By analyzing the genetic material of the cells, the researchers confirmed the treatment successfully activated the processes needed for tissue repair.

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Professor Omid Veiseh, faculty director of the Rice Biotech Launch Pad and leader of the laboratory development, said the animal trials showed strong potential for the approach.

“By maintaining a consistent presence of these signaling molecules at the wound site, we can more effectively engage the body’s natural healing response,” the scientists said.  (iStock)

“The findings show how continuous, localized cytokine delivery can support key biological pathways involved in tissue repair,” Veiseh said, according to SWNS.

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“By maintaining a consistent presence of these signaling molecules at the wound site, we can more effectively engage the body’s natural healing response.”

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He said genetic analysis “revealed coordinated upregulation of genes associated with tissue regeneration and immune modulation, providing a mechanistic basis for the functional improvements observed.”

Researcher Elizabeth Kelley of Rice University holds a cytokine-secreting patch designed to accelerate wound healing by delivering healing proteins from engineered cells continuously.  (Jared Jones/Rice University/SWNS)

The platform is fully customizable, so the engineered cells can easily be adapted to produce different combinations of proteins and growth factors, depending on what each individual patient needs.

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Study co-author Christian Schreib, Ph.D., noted that “the ability to tune both the type and timing of cytokine delivery opens the door to more precise control over the healing process.”

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Schreib said that “future work will focus on expanding the flexibility of the platform, including approaches such as optogenetic control” — using light to control cell activity — “to regulate cytokine secretion in real time.”

The technology is still in an early stage and has not yet been tested on human patients. 

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Further research is needed to understand how the technology will be used on humans.

The study was published in the journal Nature Biomedical Engineering.

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YouTube Star Javant Benton Lost 85 Lbs. With These Healthy Food Swaps

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YouTube Star Javant Benton Lost 85 Lbs. With These Healthy Food Swaps


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Javant Benton’s Healthy-Food Diet Plan To Lose Weight




















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Drinking alcohol may influence cravings for certain foods in a surprising way, study suggests

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Drinking alcohol may influence cravings for certain foods in a surprising way, study suggests

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If you find yourself reaching for a bag of chips after a few drinks, hormones may be partly to blame. Researchers suggest they can influence food cravings and may contribute to significant overeating.

Studies examining how alcohol affects people’s eating habits have produced inconsistent results, University of Sydney researchers reported in Obesity Reviews.

Alcohol on its own always adds calories, but how much it contributes to people’s total caloric intake depends on their dietary habits, the scientists observed.

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Previous research suggests alcohol consumption may increase levels of FGF21, “a hormone that increases savory (umami) preference and reduces sweet preference,” the researchers wrote. In “minimally processed food environments,” people seek foods that are both satiating and high in protein, and they limit the number of calories they eat.

On diets rich in ultra-processed savory foods and/or high-fat unprocessed meats, however, consumers eat foods that taste like the minimally processed foods, but that fail to deliver protein. The researchers refer to these foods as “protein decoys.” People who indulge in ultra-processed foods tend to eat many more calories, because they’re not satisfied without protein.

Researchers have observed that alcohol stimulates a hormone that causes people to crave savory foods and could lead them to overindulge in highly-processed foods. (iStock)

The researchers analyzed previous experimental work that involved interviews with more than 9,000 Australians. The survey found that people who reported drinking alcohol also reported eating a lot more savory foods and fewer sweet foods than the non-drinkers. People’s savory food intake increased on days they reported drinking.

People who reported drinking and consuming a savory diet with the low-protein, high-fat characteristics of an ultra-processed diet took in 40% more calories than the daily recommendation — before factoring in the alcohol.

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“Results suggest that alcohol may have contributed to the obesity epidemic,” because it increases people’s appetites, and people consuming highly processed foods eat more of the unsatiating food, the researchers hypothesized.

The researchers wrote that their observations could explain why studies on alcohol’s effect on caloric intake have been so varied, because it likely depends on the types of foods you’re eating while drinking.

They also noted that their studies did not directly measure FGF21 levels, but that they applied previous information gathered through scientific studies to make their observations. They wrote that they could not provide direct evidence of FGF21’s role in food intake.

Many people crave savory foods when they’re drinking alcohol, but the type they consume can have a major impact on caloric intake, researchers theorize. (iStock)

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The researchers also acknowledged the limitations of their research, since it was largely based on secondary evidence from a population survey.

“Advice to limit highly processed foods, including savory snack foods, may be even more critical than previously thought for reducing the risk of weight gain among adults who drink regularly,” they concluded.

Registered dietitian Morgan Beemiller, RD, LDN, based in Ohio, said she was not surprised by this study’s findings.

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“Alcohol is known to affect several biological and behavioral systems that influence food cravings,” she told Fox News Digital.

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According to Beemiller, alcohol alters appetite-regulating signals and affects the brain’s reward circuits. It also changes taste perception, she said.

To avoid the ultra-processed overeating pitfall, Beemiller recommended people eat a substantial meal prior to drinking.

“Include protein, fiber-rich carbohydrates and healthy fats,” she advised. “This combination helps slow alcohol absorption and reduces urges for convenience foods later.”

People who consumed highly-processed foods while consuming alcohol took in 40 percent more than the recommended daily number of calories, one study found. (iStock)

Chicken, rice and salad or salmon, potatoes and broccoli are sensible pre-drink meals, Beemiller said.

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“Decide on your late-night food before you start drinking,” she said. “If healthy food is already available, you are less likely to order or make convenience foods later in the evening.”

People should keep minimally processed snacks such as nuts, cheese, fruit, hummus and vegetables and hard-boiled eggs, readily available, Beemiller said. It’s also important to stay hydrated, she noted. Alternating alcoholic drinks with water can reduce total alcohol consumption, improve hydration and reduce hangover symptoms.

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While Beemiller said evidence suggests less alcohol is generally better for health, she added there are a few ways to reduce the negative impact if someone chooses to drink.

Keep your intake to a moderate level. Health risks rise the more people drink. Choose low-sugar options such as dry wines, light beers and cocktails that use fresh juices rather than syrups. Avoid high-sugar drinks, such as margaritas, daiquiris, sweet dessert wines and hard lemonades. Also beware of high-calorie mixers. Opt for sparkling water instead.

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“Choose alcohol for enjoyment, not stress management,” Beemiller said.

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