Health
Orangutan in Indonesian rainforest treats own facial wound, say researchers: ‘Appeared intentional’
An orangutan in a protected Indonesian rainforest site who sustained a facial wound treated the injury himself, according to a study published in the journal Scientific Reports earlier this month.
The male primate chewed the leaves of a plant known for its anti-inflammatory, antibacterial and pain-relieving properties — then applied a paste he made from the chewed leaves to his facial wound, according to the study.
The researchers — from the Max Planck Institute of Animal Behavior in Germany and Universitas Nasional in Indonesia — observed the orangutan, named Rakus, over the course of several weeks in the summer of 2022.
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His wound closed within five days, he noted.
Less than a month later, it appeared to be fully healed with a barely visible scar, according to the published report.
An orangutan that sustained a facial wound, shown on the left, treated it himself, according to a study published in the journal Scientific Reports earlier this month. In the image on the right, his scar is just barely noticeable. (Armas Fitra & Safruddin & TNGL & KLHK & MPI & UNAS & YEL)
This is the first observed case of active wound treatment with a “known biologically active plant substance” applied by a male Sumatran orangutan in the wild.
“He began chewing the leaves without swallowing them and using his fingers to apply the plant juice from his mouth directly onto his facial wound,” the researchers noted in their published study.
“This behavior was repeated several times.”
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“Rakus then smeared the entire wound with the plant pulp until the red flesh was fully covered with the green leaf material. He then continued feeding on this plant,” they continued.
The orangutan was observed at the Suaq Balimbing research site in Indonesia.
It is a rainforest area that is home to approximately 150 critically endangered Sumatran orangutans, according to a news release.
“The behavior of the Sumatran flanged male orangutan reported here appeared to be intentional,” the researchers wrote.
“The entire process took a considerable amount of time.”
The study authors said the animal’s facial wound likely occurred during a fight with a neighboring male.
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Isabelle Laumer, a primatologist and cognitive biologist at the Max Planck Institute of Animal Behavior in Germany — one of the lead study authors — said in an email to Fox News Digital that the primate used a climbing plant called Fibraurea tinctoria.
The plant is known for its analgesic effects and is used in traditional medicine to treat conditions such as malaria.`
When asked how Rakus knew to use that plant to treat his own wound, Laumer replied, “It is possible that wound treatment with Fibraurea tinctoria emerges through accidental individual innovation.”
She added, “Individuals may accidentally touch their wounds while feeding on Fibraurea tinctoria and thus unintentionally apply the plant’s juice to their wounds … As Fibraurea tinctoria has potent analgesic effects, Rakus may have felt an immediate pain release, causing him to repeat the behavior several times and subsequently apply solid plant matter.”
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Rakus was not born at the research site, Laumer said.
Male orangutans typically disperse over wide distances when they reach puberty to establish a new home in another area, the expert noted.
“It’s possible that orangutans at his native area showed the behavior,” Laumer said.
Dr. Isabelle Laumer, a primatologist and cognitive biologist at the Max Planck Institute of Animal Behavior in Germany, was one of the lead study authors. (Alice Auersperg)
Similar types of self-treatment have been reported in the past with other primates.
Great apes have reportedly ingested certain plants to treat parasite infections and rubbed plant material on their skin to treat sore muscles, the researchers noted.
“Maybe we can learn something about human medicine from them.”
A group of chimpanzees in Gabon was also observed applying insects to wounds, although “the efficiency of this behavior is still unknown,” according to a news release.
These types of observations could help humans with treating potential health conditions, the researchers said.
The study authors said Rakus’ facial wound likely occurred during an altercation with a neighboring male. (Saidi Agam & TNGL & KLHK & MPI & UNAS & YEL)
“So far, I have heard several reports that people have actually learned about the medicinal properties of plants through observing animals,” Laumer told Fox News Digital.
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Dr. Robin Sturtz, a veterinarian who was not involved in the study, commented on the findings.
“It’s great that they caught these images,” she told Fox News Digital, but noted that the published report is observational.
The primate used a climbing plant called Fibraurea tinctoria, the researchers said, to help a facial wound to heal. (Saidi Agam & TNGL & KLHK & MPI & UNAS & YEL)
“We need to see if it’s repeated in this or another animal,” Sturtz told Fox News Digital.
“They are incredibly smart, though, and do learn quickly,” she added. “Maybe we can learn something about human medicine from them.”
Caroline Schuppli, one of the co-authors of the published study, noted in a news release that forms of active wound treatment are not limited to humans.
“[They] can also be found in both African and Asian great apes,” she stated.
“It is possible that there exists a common underlying mechanism for the recognition and application of substances with medical or functional properties to wounds, and that our last common ancestor already showed similar forms of ointment behavior.”
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A popular class of weight-loss drugs may prevent life-threatening cardiac complications by opening microscopic blood vessels that often remain blocked after a heart attack, according to a study published this week in Nature Communications.
The research, led by the University of Bristol and University College London, identified a biological brain-gut-heart signaling pathway.
This discovery appears to explain how GLP-1 drugs — which mimic glucagon-like peptide-1, a hormone that helps regulate blood sugar and appetite — protect heart tissue from a condition known as “no-reflow.”
“In nearly half of all heart attack patients, tiny blood vessels within the heart muscle remain narrowed, even after the main artery is cleared during emergency medical treatment,” Dr. Svetlana Mastitskaya, the study’s lead author and a senior lecturer at Bristol Medical School, said in a press release.
“This results in a complication known as ‘no-reflow,’ where blood is unable to reach certain parts of the heart tissue.”
In nearly half of all heart attack patients, tiny capillaries (blood vessels) remain narrowed even after the main blocked artery is cleared. (iStock)
This lack of blood flow increases the risk of heart failure and death within a year. GLP-1 medications could prevent this, according to the researchers.
How it works
When the GLP-1 hormone is released in the gut or administered as a drug, it sends a signal to the brain, which then sends a signal to the heart that switches on special potassium channels in tiny cells called pericytes.
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When these channels open, the pericytes relax, which allows the small blood vessels (capillaries) to widen and improve blood flow to the heart muscle, the researchers noted.
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The new study used animal models and cellular imaging to track how GLP-1 interacts with heart tissue. When the researchers removed the potassium channels, the drugs no longer protected the heart — confirming they play a key role.
The findings suggest that existing GLP-1 medications, already used for type 2 diabetes and obesity, could be repurposed as emergency treatments. (iStock)
The findings suggest that existing GLP-1 medications, already used for type 2 diabetes and obesity, could be repurposed as emergency treatments during or immediately after a heart attack to reduce tissue damage.
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The researchers noted several limitations, including that the study relied on animal models.
Clinical trials are necessary to determine whether the brain-gut-heart pathway operates with the same timing and efficacy in humans.
While the study highlights the drug’s immediate benefits during a heart attack, it des not establish whether long-term use of these drugs provides a pre-existing level of protection. (iStock)
Additionally, while the study highlights the drug’s immediate benefits during a heart attack, it does not establish whether long-term use of the medication provides a pre-existing level of protection.
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The research was primarily funded by the British Heart Foundation.
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Collagen supplements have exploded in popularity, touted as everything from an anti-aging miracle to a muscle recovery booster.
But a sweeping new review conducted by U.K. researchers suggests that while collagen may help improve skin elasticity and ease arthritis pain, it does little for athletic performance or wrinkle reduction.
Researchers from Anglia Ruskin University analyzed 16 systematic reviews and 113 randomized controlled trials involving nearly 8,000 participants worldwide, which they say is the most extensive evaluation of collagen’s health effects to date.
The review found consistent evidence that collagen supplementation improves skin elasticity and hydration over time and provides significant relief from osteoarthritis-related joint pain and stiffness, according to findings published in Aesthetic Surgery Journal Open Forum.
A large U.K. review found that collagen supplements may improve skin elasticity and hydration over time. (iStock)
The researchers, however, did not find meaningful improvements in post-exercise muscle recovery, soreness or tendon mechanical properties (strength, springiness and stretch resistance).
“Collagen is not a cure-all, but it does have credible benefits when used consistently over time, particularly for skin and osteoarthritis,” co-author Lee Smith, professor of public health at Anglia Ruskin University, said in a statement.
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“Our findings show clear benefits in key areas of healthy aging, while also dispelling some of the myths surrounding its use,” Smith added.
Collagen, the most abundant protein in the body, supports skin, bones, tendons, cartilage and connective tissue, according to experts. Natural collagen production begins to drop in early adulthood and declines more sharply with age.
The study found that collagen supplements may help reduce joint pain and stiffness in people with osteoarthritis. (iStock)
The review found that long-term collagen supplementation was linked to improved skin firmness and hydration, but did not help skin roughness — a proxy for visible wrinkles.
Benefits appear to accumulate gradually, suggesting that collagen should not be viewed as an “anti-wrinkle ‘quick fix,’ but as a foundational dermal support for individuals seeking holistic skin maintenance,” the researchers said.
“If we define anti-aging as a product or technique designed to prevent the appearance of getting older, then I believe our findings do support this claim for some parameters,” Smith told the BBC. “For example, an improvement in skin tone and moisture is associated with a more youthful-looking appearance.”
Collagen supplementation was linked to reduced pain and stiffness in people with osteoarthritis, with stronger benefits seen over longer periods of use, and showed modest improvements in muscle mass and tendon structure that may support healthy aging.
Collagen did not significantly improve skin roughness, a marker of visible wrinkles. (iStock)
However, it did not show meaningful results when used as a fast-acting sports performance supplement, and evidence for benefits related to cholesterol, blood sugar, blood pressure and oral health was mixed or inconclusive.
Dr. Daniel Ghiyam, a California-based physician and longevity specialist, said the findings align with what he sees in clinical practice.
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“Collagen is a targeted support tool, not a foundation of health or performance,” Ghiyam, who was not involved in the study, told Fox News Digital. “When marketed that way, it makes sense. When marketed as a cure-all, it doesn’t hold up to the data.”
The authors noted that while many previous collagen studies have received financial support from the supplement industry, the current review did not receive industry funding.
Experts say collagen supplements may offer modest benefits for skin hydration and joint comfort, but they are not a cure-all. (iStock)
The team called for more high-quality clinical trials examining long-term outcomes, optimal dosages and differences between collagen sources, such as marine, bovine and plant-based alternatives.
Among its limitations, the review could not determine whether certain forms of collagen work better than others or what the optimal regimen should be.
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While the review included randomized controlled trials, the quality of the studies varied, with newer research generally showing stronger results.
Experts say more data and studies are needed to build on the findings. They also noted that diet plays a crucial role in skin health.
Collagen supplements, often sold as powders or pills, may improve skin elasticity and ease joint pain, experts say. (iStock)
Dr. Erum Ilyas, a Pennsylvania-based dermatologist and chair of dermatology at Drexel University College of Medicine, noted that the review analyzed previously published meta-analyses rather than generating new primary data.
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“At this time, I have not seen sufficiently strong independent evidence to routinely recommend collagen supplements to my patients,” Ilyas, who was not involved in the review, told Fox News Digital.
“Although some studies show modest improvements in markers such as hydration and elasticity, there remains limited independent, biopsy-confirmed evidence demonstrating sustained increases in dermal collagen content,” she added.
Fox News Digital has reached out to the researchers for comment.
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