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Men going bald turn to 'new Botox' for hair loss treatment

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Men going bald turn to 'new Botox' for hair loss treatment

The cure for baldness has long been a scientific enigma.

Yet advanced treatment options and hair-loss clinics have continued to emerge — and researchers are making progress on finding fixes for balding.

UCLA scientists recently alerted a “breakthrough” discovery involving a molecule named PP405 that can “waken long-slumbering but undamaged” hair follicles, according to a press release.

CURE FOR MEN’S HAIR LOSS COULD BE FOUND IN SUGAR STORED IN THE BODY, STUDY SUGGESTS

In a 2023 clinical trial, researchers found that applying PP405 as a topical medicine to the scalp at bedtime showed “statistically significant” results.

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They believe this treatment will produce “full ‘terminal’ hair rather than the peach fuzz variety.”

PP405 is now in Phase 2 clinical trials for men and women with androgenetic alopecia, according to a researcher.  (iStock)

William Lowry, Ph.D., a co-researcher at UCLA Broad Stem Cell Research Center, told Fox News Digital that although this research is promising, “cure is a strong word.”

“There are only two FDA-approved treatments for androgenetic alopecia (AGA, or pattern baldness): minoxidil and finasteride,” he said in an interview. 

“They are both limited in efficacy and improve hair in only a portion of patients who take them.”

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Other treatment options include supplements, red light therapy, platelet-rich plasma injections and hair transplantation, Lowry said, although these have not undergone “definitive clinical trials and can be expensive, time-consuming and limited in efficacy.”

He added, “None of these are curative, meaning none of them permanently restore all hair lost due to AGA.”

Some treatment options for hair loss are “limited in efficacy,” said a co-researcher (not pictured) at UCLA Broad Stem Cell Research Center in LA. (iStock)

Lowry and his fellow researchers have discovered that hair follicle stem cells have a “distinct metabolism from other cells in the follicle.”

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He said, “We found that promoting this metabolism can accelerate stem cell activation, which makes new hairs grow. We subsequently developed drugs that can drive this effect in various models of hair loss that reflect the multifactorial drivers of androgenetic alopecia in patients.”

HAIR LOSS AND PROSTATE MEDICATION COULD ALSO REDUCE HEART DISEASE RISK, STUDY FINDS

PP405 has become the leading candidate for hair-loss treatment as part of this new class of drugs.

“We are excited about the opportunity to bring a novel treatment option to patients with hair loss based on strong science and rigorous clinical trials,” he said. 

“Additionally, because the mechanism of action we discovered is distinct from previous approaches, it can potentially be used in combination with other therapies.”

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“This novel class of drugs drove the formation of Pelage Pharmaceuticals, a regenerative medicine biotech developing new treatments for hair loss, with PP405 being the lead candidate.” (iStock)

Brendan Camp, M.D., a Manhattan-based dermatologist, told Fox News Digital in an interview that hair loss is a condition that “affects many and can have a negative impact on people’s psychosocial health.” 

So identifying a potential new hair-loss treatment is an “exciting step for patients and providers in the management of what can otherwise be a difficult condition to treat.”

‘New Botox’

Camp agreed there is an “unmet need” for hair-loss treatment and that there’s growing interest in providing solutions and offering hair restoration services more widely.

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As cosmetic injections such as Botox and fillers have continued to be popular anti-aging and beauty treatments, hair-loss and restoration med spas are similarly surfacing nationwide.

The clinics offer a variety of services for men and women given the availability of modern options.

Early intervention when to balding is “key,” said one expert.  (iStock)

Dr. Amy Spizuoco, DO, of True Dermatology in New York, dubbed balding treatments in this capacity the “new Botox.” 

“With advances in treatments like minoxidil, finasteride, PRP (platelet-rich plasma) therapy, hair transplants and the latest stem cell research, hair restoration has become more accessible and effective,” she told Fox News Digital.

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“And much like Botox is used preventatively, younger people are tackling hair loss at the first signs rather than waiting until it’s severe.”

Camp added that while there are many hair-loss treatment options available, the response will look different for each person. 

Medications such as minoxidil, finasteride and dutasteride can “slow down the process and even grow hair back,” one expert said, while procedures such as PRP, low-level laser therapy and hair transplants are also effective. (iStock)

“When looking for a treatment, stick to those with a well-established body of evidence and data to support their use, such as minoxidil, finasteride and spironolactone (in the case of female-pattern hair loss),” he advised.

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And be sure to get “the advice of a board-certified dermatologist when at-home treatments are not effective,” he also said. 

These treatments are “typically used indefinitely” and should be tested for three to four months before being ruled out as effective or not, the dermatologist added.

Spizuoco said that while hair loss is common, early intervention with the right treatment plan can “significantly slow it down or possibly reverse it.”

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The Best Time To Take ‘Nature’s Ozempic’ Berberine for Weight Loss and Blood Sugar Control, According to an MD

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The Best Time To Take ‘Nature’s Ozempic’ Berberine for Weight Loss and Blood Sugar Control, According to an MD


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Study reveals why chewing gum might actually help with focus and stress relief

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Study reveals why chewing gum might actually help with focus and stress relief

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Humans have been chewing gum for thousands of years, long after the flavor fades and without any clear nutritional benefit.

The habit dates back at least 8,000 years to Scandinavia, where people chewed birchbark pitch to soften it into a glue for tools. Other ancient cultures, including the Greeks, Native Americans and the Maya, also chewed tree resins for pleasure or soothing effects, National Geographic recently reported.

In the late 19th and early 20th centuries, William Wrigley Jr. transformed chewing gum from a novelty into a mass consumer habit through relentless and innovative marketing. His brands, including Juicy Fruit and Spearmint, promoted gum as a way to calm nerves, curb hunger and stay focused.

COMMON DENTAL HEALTH ISSUE MAY HINT AT MORE DANGEROUS MEDICAL CONDITION

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“Are you worried? Chew gum,” an article from 1916 said, according to Kerry Segrave’s book, “Chewing Gum in America, 1850-1920: The Rise of an Industry.” “Do you lie awake at night? Chew gum,” it continued. “Are you depressed? Is the world against you? Chew gum.”

Advertisements have long framed chewing gum as a tool for stress relief and mental sharpness. (Keystone View Company/FPG/Archive Photos/Getty Images)

In the 1940s, a study found chewing resulted in lower tension but couldn’t say why. 

“The gum-chewer relaxes and gets more work done,” The New York Times wrote at the time about the study’s results.

Gum became an early form of wellness, and companies are trying to revive that idea today as gum sales decline, according to National Geographic.

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GARLIC EXTRACT RIVALS TRADITIONAL MOUTHWASH FOR DENTAL HYGIENE IN SURPRISING NEW REVIEW

But only now are scientists finally beginning to understand the biology behind those long-standing beliefs.

Chewing gum may briefly affect attention and stress-related brain activity, according to studies. (iStock)

A 2025 review by researchers at the University of Szczecin in Poland analyzed more than three decades of brain-imaging studies to examine what happens inside the brain when people chew gum. Using MRI, EEG and near-infrared spectroscopy research, the authors found that chewing alters brain activity in regions tied to movement, attention and stress regulation.

The findings help clarify why the seemingly pointless task can feel calming or focusing, even once the flavor has faded.

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Chewing gum activated not only the brain’s motor and sensory networks involved in chewing, but also higher-order regions linked to attention, alertness and emotional control, the review found. EEG studies found brief shifts in brain-wave patterns linked to heightened alertness and what researchers call “relaxed concentration.”

Humans have chewed gum for pleasure for thousands of years, according to reports. (iStock)

“If you’re doing a fairly boring task for a long time, chewing seems to be able to help with concentration,” Crystal Haskell-Ramsay, a professor of biological psychology at Northumbria University, told National Geographic.

The review also supports earlier findings that gum chewing can ease stress, but only in certain situations. In laboratory experiments, people who chewed gum during mildly stressful tasks such as public speaking or mental math often reported lower anxiety levels than those who didn’t.

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Chewing gum did not, however, consistently reduce anxiety in high-stress medical situations, such as immediately before surgery, and it offered no clear benefit when participants faced unsolvable problems designed to induce frustration.

Some studies suggest chewing gum can reduce stress in mild situations but not extreme ones. (iStock)

Across multiple studies, people who chewed gum did not remember lists of words or stories better than those who didn’t, the researchers also found, and any boost in attention faded soon after chewing stopped.

Gum may simply feed the desire to fidget, experts suspect.

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“Although these effects are often short-lived, the range of outcomes … underscores chewing gum’s capacity to modulate brain function beyond simple oral motor control,” the researchers wrote.

“However, at this time, the neural changes associated with gum chewing cannot be directly linked to the positive behavioral and functional outcomes observed in studies,” they added.

A 2025 review analyzed decades of MRI, EEG and near-infrared spectroscopy studies on gum chewing. (iStock)

Future research should address longer-term impacts, isolate flavor or stress variables and explore potential therapeutic applications, the scientists said.

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The findings also come with caveats beyond brain science. Although sugar-free gum may help reduce cavities, Fox News Digital has previously reported that dentists warn acids, sweeteners and excessive chewing may harm teeth or trigger other side effects.

Fox News Digital has reached out to the study’s authors for comment.

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The Best Time To Take Turmeric for Weight Loss and How To Maximize Results

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The Best Time To Take Turmeric for Weight Loss and How To Maximize Results


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