Health
Men face hidden heart risk years earlier than women, study suggests
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Men are at a much higher risk of heart attacks than women earlier in life, a new study reveals.
Researchers at Northwestern University found that men start to develop coronary heart disease years earlier than women, with differences emerging as early as the mid-30s, according to a press release.
The study, published in the Journal of the American Heart Association (JAHA), analyzed data from more than 5,000 adults, aged 18 to 30, from the mid-1980s through 2020, as part of the Coronary Artery Risk Development in Young Adults (CARDIA) analysis.
INSUFFICIENT SLEEP LINKED TO MAJOR HIDDEN HEALTH RISK, STUDY REVEALS
Men reached a 5% incidence of cardiovascular disease, including heart attack, stroke and heart failure, at around 50 years old compared to 57 for women.
Coronary heart disease, which is when blood vessels that supply the heart muscle become narrowed or blocked, was the main driver of the difference, as men reached a 2% incidence more than a decade before women. Stroke and heart failure emerged later in life.
Heart disease risk among men rises faster at around 35 years of age, research finds. (iStock)
Men’s risk began rising faster at around age 35 and remained high throughout midlife, according to the research. Everyone in the study was under 65 years old at the last follow-up.
Current guidelines generally recommend cardiovascular risk assessment beginning around age 40, which some experts say may miss an important window for early prevention.
COMMON DENTAL HEALTH ISSUE MAY HINT AT MORE DANGEROUS MEDICAL CONDITION
Heart disease develops over decades, with early markers detectable in young adulthood, according to senior study author Alexa Freedman, assistant professor of preventive medicine at Northwestern University Feinberg School of Medicine.
Lifestyle factors are most likely the main driver of cardiovascular events in men, a cardiologist suggests. (iStock)
“Our findings highlight the importance of promoting heart health screening and prevention in young adulthood, especially for young men,” Freedman told Fox News Digital.
The researchers emphasized the importance of looking beyond standard measures of heart risk, like cholesterol or blood pressure, and considering a “broader range of biological and social factors.”
HEART STUDY FLAGS DANGEROUS RHYTHM RISK FOR ENDURANCE ATHLETES OVER 50
Dr. Andrew Freeman, cardiologist and director of clinical cardiology at National Jewish Health in Denver, was not involved in the study but commented on the findings.
“We have always known that men tend to manifest and typically die earlier from things like heart attacks and strokes compared to women,” he told Fox News Digital.
The lead researcher recommends more frequent or early CT angiograms to help prevent cardiac events. (iStock)
Although the study did not identify why more men are predisposed to heart issues than women, Freeman said factors like hormonal differences, diet and physical activity could come into play.
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“The standard American lifestyle makes us all sick, and then men seem to be more prone to developing this disease earlier,” the cardiologist told Fox News Digital.
“We are more exposed to toxins than ever before in virtually every part of our food supply,” he added. “We already know well that air pollution, light pollution and sound pollution are all associated with earlier heart disease.”
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Americans are also more sedentary, get less sleep, are more stressed and are less socially connected, all of which can increase cardiovascular diseases, Freeman added.
“I think this study is really underscoring that it’s time for some big changes,” he said.
Regular daily exercise is one way to set up your heart for a long life, experts agree. (iStock)
The doctor shared the following five “healthspan” tips to help prevent heart health issues.
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- Limit toxin exposure in the form of alcohol, tobacco, marijuana, nicotine and air pollution
- Eat a predominately low-fat, whole-food, plant-based diet
- Exercise regularly, ideally 20 to 30 minutes every day at a level of breathlessness (with sign-off from a doctor)
- Partake in stress-relieving activities and mindfulness exercises
- Get adequate, uninterrupted sleep
- Cultivate a strong support network of friends and family
“We need to do everything we can to clean up our lifestyles and reduce our disease burden.”
Freeman also recommends addressing any comorbidities, like high blood pressure, high cholesterol and obesity.
Those at a higher risk of cardiovascular events may want to consider earlier screening, although Freeman suggested that early prevention efforts should apply to everyone.
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“Coronary disease is manifesting earlier than ever here in the U.S., and we need to do everything we can to clean up our lifestyles and reduce our disease burden,” he said. “If you’re a man, you’ve got to be extra aggressive earlier in life.”
Health
Dementia risk signals could lie in simple blood pressure readings, researchers say
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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.
That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.
The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.
LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).
Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.
The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”
Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.
HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS
In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.
For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)
The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.
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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”
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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.
Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)
“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.
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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.
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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.
Health
Everything You Need To Know About Zepbound for Weight Loss, Including Costs
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Health
‘Gas station heroin’ banned in another state amid nationwide crackdowns
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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.
Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.
Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.
HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION
Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.
Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.
Tianeptine can be more potent than morphine and addictive opioids. (iStock)
Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.
Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.
The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.
Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)
Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.
“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.
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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.
Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”
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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”
New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.
“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)
“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”
Schwaner said he believes the substance requires national regulation due to its addictive qualities.
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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.
Fox News Digital reached out to the FDA for comment.
Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.
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