Health
Measles more likely to be severe among malnourished, RFK says
As measles cases continue to spread in several U.S. states, the spotlight is on prevention of the highly contagious disease.
While vaccines are widely regarded as the first line of defense, some experts have suggested that nutrition plays a role in reducing the severity of the disease.
HHS Secretary Robert F. Kennedy Jr. discussed the topic during a recent exclusive interview with Dr. Marc Siegel, clinical professor of medicine at NYU Langone Health and Fox News’ senior medical analyst.
WATCH FULL INTERVIEW WITH DR. MARC SIEGEL AND RFK JR. ON FOX NATION
“We need to understand the relationship between good health and chronic disease,” RFK Jr. told Siegel.
“If you are healthy, it’s almost impossible for you to be killed by an infectious disease, in modern times — because we have nutrition … and access to medicines. What we need is good science on all of these things so that people can make rational choices.”
As measles cases continue to spread in several U.S. states, the spotlight is on prevention of the highly contagious disease. (iStock)
During the interview, RFK noted that in Texas — where more than 200 cases of measles have been reported in the current outbreak — malnourishment may be a factor.
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“The doctors that I’m talking to on the ground, the leaders of the community, are reporting that the people who are getting sick are people who are [malnourished],” he said.
“There’s a lot of poverty in that area, [which] is kind of a food desert,” RFK added.
In 1963, prior to the vaccine’s introduction, between 400 and 500 people died from measles each year in the U.S., according to the Centers for Disease Control and Prevention (CDC).
“The doctors that I’m talking to on the ground, the leaders of the community, are reporting that the people who are getting sick are people who are [malnourished],” RFK Jr. said. (iStock)
“Almost all of them were malnourished children,” RFK said. “Measles still is a very, very lethal disease in foreign countries and developed countries where there is low malnutrition.”
He added, “The best thing Americans can do is to keep themselves healthy. It is very, very difficult for measles to kill a healthy, well-nourished person.”
“We see a correlation between people who get hurt by measles and people who don’t have good nutrition.”
Nutrition is “critical” for overall disease prevention, the HHS secretary told Siegel.
“We need to eat good foods. We need whole foods. We need to get plenty of exercise,” he said.
“We see a correlation between people who get hurt by measles and people who don’t have good nutrition or don’t have a good exercise regimen.”
Infectious disease experts weigh in
Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, agreed that measles is more likely to severely affect children in developing countries who are extremely malnourished.
“Historically, less than 1% of American children die from measles, while the Pan American Health Organization reports that as [many] as 10% of children die from measles in some developing countries, and it has been reported as high as 25% to 50% in a study of malnourished African infants,” he told Fox News Digital.
“Historically, less than 1% of American children die from measles, while the Pan American Health Organization reports that as high as 10% of children die from measles in some developing countries.” (Getty Images)
The lack of quality medical care in many areas of the developing world also contributes to disease severity, Glanville noted.
“While better nutrition is important for American children, it’s unlikely to make a difference when it comes to measles infection or severity — 90% of well-fed but unvaccinated American children exposed to measles will become infected, around 20% of those children will be hospitalized, and 0.1-1% of those children will die.”
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Dr. Trish Perl, an infectious disease expert at UT Southwestern Medical Center in Dallas, Texas, noted that malnutrition can impair some of the immune system responses to many infections — but in the case of measles, the answer is “complicated.”
“For example, malnutrition may decrease the robustness of the response to the MMR vaccine,” she told Fox News Digital.
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“The vaccine is still effective, but in some cases, an additional dose may be required.”
Studies have shown that children who are malnourished with vitamin A deficiency and living in low- and middle-income countries have more severe illness with measles infection, face an increased risk of death and blindness, and take longer to get better, Perl said.
The CDC recommends that adults and teens are up-to-date on MMR (measles, mumps and rubella) vaccinations with either one or two doses, depending on individual risk factors. (iStock)
“There is no treatment for measles beyond supportive care,” she said. “However, in low- and middle-income countries — whose mortality is greater than 1% — the World Health Organization recommends vitamin A (two doses) to reduce the severity of measles and prevent complications.”
The issue isn’t as prevalent in the U.S., where vitamin A deficiency is “extremely rare,” the doctor added.
There haven’t been formal studies into whether giving vitamin A to children with measles in the U.S. or other high-income countries prevents complications, according to Perl.
The American Academy of Pediatrics, however, recommends that hospitalized children with severe measles receive two doses of vitamin A as supervised by a healthcare provider.
Dr. Jonathan Jennings, a board-certified internist with the Medical Offices of Manhattan, also noted that multiple studies have found nutrition can “heavily impact” the clinical course of children who contract the measles virus.
“The risk of fatal outcomes is increased in children who are already malnourished prior to being infected,” he told Fox News Digital.
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“The infection has been known to worsen the nutritional status, which impacts the child’s immune system and ability to recover.”
Jennings recommends a balanced diet with a variety of colorful fruits, vegetables, protein and healthy fats as a means of preventing complications once infected with the virus.
An expert recommended a balanced diet with a variety of colorful fruits, vegetables, protein and healthy fats as a means of preventing complications once infected with the virus. (iStock)
“Vitamin A-containing foods are particularly helpful, such as carrots, spinach and dairy products,” he said.
“Many studies have identified vitamin A supplementation as a means to prevent eye damage, which is a complication of the measles infection.”
Nutrition not substitute for vaccine, experts say
While proper nutrition is important for preventing many chronic health conditions, Perl emphasized that vaccination is the “only documented method” of preventing measles infection and “is the most important action anyone can take.”
“Vaccination should be given whether an individual is malnourished or not.”
“The vaccine has been in use since 1963 and is considered extremely safe,” she said.
“Vaccination should be given whether an individual is malnourished or not, as it is the only way to prevent measles.”
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RFK also recognized the importance of vaccines, noting that the HHS is “making sure that anybody who wants the vaccine can get that vaccine.”
“The measles vaccine protects the community,” he told Dr. Siegel. “We are recommending that people in this country get vaccines … [and] we are also respectful of their personal choices.”
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Jennings also reiterated the importance of vaccines.
“The most effective way to protect and prevent you and your family from getting measles is to get everyone vaccinated against the virus,” he said.
The CDC recommends that adults and teens are up-to-date on MMR (measles, mumps and rubella) vaccinations with either one or two doses, depending on individual risk factors.
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Eating too much salt has long been linked to high blood pressure, but new research suggests it could trick the immune system into prematurely aging the blood vessels.
A preclinical study recently published in the Journal of the American Heart Association has identified a biological chain reaction that links a salty diet to cardiovascular decay.
Scientists at the University of South Alabama observed that mice on a high-salt diet experienced rapid deterioration in their blood vessel function.
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After just four weeks of high sodium intake, the small arteries responsible for regulating blood flow lost their ability to relax, according to a press release.
The team found that the cells lining these vessels had entered a state of cellular senescence, a form of premature cellular aging in which cells stop dividing and release a mix of inflammatory signals that can damage surrounding tissue.
Excess salt has long been linked to high blood pressure, but a new study goes deeper into its effects on the cardiovascular system. (iStock)
The researchers tried to replicate this damage by exposing blood vessel cells directly to salt in a laboratory dish, but the cells showed no harmful effects.
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This suggests that salt isn’t directly causing damage to the vascular lining but that the real culprit may be the body’s own defense mechanism, the researchers noted.
Excess salt may trigger the immune system to release a molecule called interleukin-16 (IL-16), which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study.
Excess salt may trigger the immune system to release a molecule called interleukin-16, which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study. (iStock)
Once these cells age, they fail to produce nitric oxide, the essential gas that tells arteries to dilate and stay flexible.
To test whether this process could be reversed, the team turned to a class of experimental drugs known as senolytics.
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Using a cancer medication called navitoclax, which selectively clears out aged and dysfunctional cells, the researchers were able to restore nearly normal blood vessel function in the salt-fed mice, the release stated.
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By removing the decaying cells created by the high-salt diet, the drug allowed the remaining healthy tissue to maintain its elasticity and respond correctly to blood flow demands.
Excess salt may trigger the immune system into stopping the cells from dividing, the study suggests. (iStock)
The study did have some limitations. The transition from mouse models to human treatment remains a significant hurdle, the team cautioned.
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Senolytic drugs like navitoclax are still being studied for safety, and the team emphasized that previous trials have shown mixed results regarding their impact on artery plaque.
Additionally, the researchers have not yet confirmed whether the same IL-16 pathway is the primary driver of vascular aging in humans.
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Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests.
The observational study, led by Jorge Nieva, M.D., of the USC Norris Comprehensive Cancer Center at Keck Medicine, was presented this month at the American Association for Cancer Research (AACR) annual meeting in San Diego. It has not yet been peer-reviewed.
Researchers looked at dietary, smoking and demographic data for 187 patients who were diagnosed with lung cancer at age 50 or younger.
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They found that among non-smokers, there was a link between healthier-than-average diets – rich in fruits, vegetables and whole grains – and the chance of lung cancer development.
Young lung cancer patients ate more servings of dark green vegetables, legumes and whole grains compared to the average U.S. adult, the researchers found.
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests. (iStock)
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association.
“Commercially produced (non-organic) fruits, vegetables and whole grains are more likely to be associated with a higher residue of pesticides than dairy, meat and many processed foods,” according to Nieva. He also noted that agricultural workers exposed to pesticides tend to have higher rates of lung cancer.
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“There is a large subset of lung cancer patients whose disease is not caused by smoking,” Nieva told Fox News Digital.
The disease is becoming more common in non-smokers 50 and younger, especially women – despite the fact that smoking rates have been falling for decades, the researcher noted.
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association. (iStock)
“These patients tend to have eaten much healthier diets before their diagnosis than the average American,” he went on. “We need to support research into understanding why Americans – and women in particular – who no longer smoke very much are still having lung cancer,” he said.
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The study did have some limitations, Nieva acknowledged, primarily that it relied on survey data and was limited by the participants’ memories of their food intake.
“Also, the survey participants were self-selected, and this could have biased the findings,” he told Fox News Digital.
“There is a large subset of lung cancer patients whose disease is not caused by smoking.”
The researchers did not test specific foods for pesticides, relying instead on average pesticide levels for certain types of food. Looking ahead, they plan to test patients’ blood and urine samples to directly measure pesticide levels, Nieva said.
Although the study shows only an association and does not prove that pesticides caused lung cancer, Nieva recommends that people wash their produce before eating and choose organic foods whenever possible.
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“This work represents a critical step toward identifying modifiable environmental factors that may contribute to lung cancer in young adults,” said Nieva. “Our hope is that these insights can guide both public health recommendations and future investigation into lung cancer prevention.”
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but is by no means certain,” a doctor said. (AP Photo/Charlie Neibergall)
Dr. Marc Siegel, Fox News senior medical analyst, said the study is “interesting,” but that it “raises far more questions than it answers.”
“It is a small study (around 150) and observational, so no proof,” the doctor, who was not involved in the research, told Fox News Digital.
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“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but it is by no means certain,” Siegel went on. “How much exposure is needed? How much of it gets into food and in which areas? This requires much further study.”
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Kayla Nichols, communications director for Pesticide Action & Agroecology Network, a distributed global network, said the organization agrees with the study’s conclusion that more research should be done on the rise in lung cancer, particularly in individuals eating diets higher in produce and fiber.
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” the researcher told Fox News Digital. (iStock)
“There is a bounty of existing research that already links pesticide exposure to increased risk of multiple types of cancers,” Nichols, who was also not involved in the study, told Fox News Digital. She called for more research on chronic, low-level exposures to pesticides, as well as more effective policies to protect the public from pesticide residues on food.
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The study was supported by the National Institutes of Health and the National Cancer Institute, as well as industry partners including AstraZeneca and Genentech, among others.
Fox News Digital reached out to several pesticide companies and trade groups for comment.
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