Health
Marijuana Dependence Linked to Higher Risk of Death
Hospital and emergency room patients diagnosed with cannabis use disorder — defined as an inability to stop using cannabis even when the drug is causing harm — died at almost three times the rate of individuals without the disorder over the next five years, according to a study published on Thursday, the largest on the subject.
Patients with cannabis use disorder were 10 times as likely to die by suicide as those in the general population. They were also more likely to die from trauma, drug poisonings and lung cancer. Those numbers suggest that cannabis use disorder is about half as dangerous as opioid addiction and slightly less dangerous than alcohol use disorder, the researchers said.
A second report, published on Tuesday, found that more cases of schizophrenia and psychosis in Canada have been linked to cannabis use disorder since the drug was legalized.
“Many people think, ‘Oh, cannabis is not harmful — it’s organic, it’s natural; how great,’” said Dr. Laura Bierut, a psychiatrist at Washington University School of Medicine in St. Louis who is an author of an editorial accompanying the study of death risk. But the marijuana sold today is far more potent, and more harmful, than what baby boomers smoked in the 1960s and 1970s, she said.
“It is a public health threat just like alcohol,” Dr. Bierut said.
Recent research suggests that three in 10 cannabis users will develop cannabis use disorder, defined as being unable to stop using cannabis even though it’s causing serious health and social problems. As with alcohol, many people use marijuana recreationally without adverse effects or addiction.
The researchers took advantage of records in Ontario that capture millions of residents’ encounters with the government health system, which covers 97 percent of the population there.
From the records, the scientists in Thursday’s study identified 106,994 people who were diagnosed with cannabis use disorder during an emergency department visit or hospitalization between 2006 and 2021.
The researchers linked the records with vital statistics records and found that 3.5 percent of them died within five years of treatment for the disorder. In a matched comparison group of people of the same age and sex, the death rate was 0.6 percent.
The authors then made adjustments to account for other risk factors that may have contributed to their deaths, including mental health disorders, other substance use and conditions like heart disease and cancer.
Even when taking deaths by those other causes out of the equation, the researchers concluded that patients with cannabis use disorder were at a 2.8-fold increased risk of death compared with the general population. The risk was greatest in young adults ages 25 to 44.
Dr. Daniel Myran, an assistant professor of family medicine at University of Ottawa and the study’s first author, noted that these are most likely underestimates of cannabis’s toll.
“Our estimate is that for every person treated for C.U.D. there are another three who didn’t seek care,” he said. “So this is not just C.U.D., but bad enough that they sought care for it.”
He also noted that the study could not conclusively determine whether the cannabis itself increased death risk, or whether it was other lifestyle or health factors that happen to be more common among heavy cannabis users.
“Either way, this group is really, really high risk, and could benefit from intervention and monitoring and prevention,” he said.
On Tuesday, the same research group published a study looking at whether Canada’s recent legalization of marijuana affected rates of psychosis and schizophrenia.
Cannabis use has been associated with the development of schizophrenia, a serious mental illness, as well as transient psychotic episodes characterized by a loss of contact with reality. Some research has found no association between cannabis legalization and an increase in these disorders, but many studies are too small to detect changes in the prevalence of psychotic disorders, which are rare.
The new study analyzed cannabis-linked psychosis in Canada during three periods: before the country made cannabis legal (2006 to 2015), amid widening use of medical and nonmedical cannabis (2015-2018) and after the recreational use of cannabis was made legal (2018 to 2022).
The rates of schizophrenia were stable over time. But the percentage of cases attributable to cannabis use disorder increased to 10.3 percent during the legalization period, up from 3.7 percent before legalization, the authors found. The rate of psychosis (without a diagnosis of schizophrenia) nearly doubled after legalization.
Young adults ages 19 to 24 were most vulnerable, said Jodi Gilman, an associate professor of psychiatry at Harvard Medical School who wrote a commentary about the study.
“This is a period of the life span when the brain is still developing and still vulnerable to the effects of cannabis,” Dr. Gilman said. Psychosis and schizophrenia are also known to develop in young adulthood, she added, “so you have a double hit.”
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
NEWYou can now listen to Fox News articles!
Comedian Amy Schumer, 44, has recently come clean about her struggle with Cushing’s syndrome, leading to a dramatic weight loss.
Schumer’s transformation has sparked conversation online, to which she responded in a now-deleted Instagram post that shut down speculation about cosmetic enhancements.
“I didn’t lose 30lbs — I lost 50,” she emphasized on social media, adding that she does not get Botox or filler.
AMY SCHUMER DROPPED 50 POUNDS TO BATTLE DISEASE THAT ‘CAN KILL YOU’ IF UNTREATED
Schumer doubled down that her weight loss was not about her appearance, but about staying alive.
“Not to look hot, which does feel fun and temporary,” she said. “I did it to survive. I had a disease that makes your face extremely puffy that can kill you, but the internet caught it and that disease has cleared.”
Amy Schumer attends Variety’s 2024 Power of Women: New York event on May 2, 2024, in New York City on the left. On the right, Schumer later poses for a photo posted to Instagram after her weight loss. (Marleen Moise/WireImage; Amy Schumer/Instagram)
“Sorry for whatever feeling it’s giving you that I lost that weight,” she added. “I’ve had plastic surgery over the years and I use [Mounjaro]. Sorry to anyone they let down. I’m pain free. I can [play] tag with my son.”
ON A GLP-1? HOW TO SURVIVE HOLIDAY MEALS WITHOUT DERAILING YOUR PROGRESS
The actress also addressed her shifting hormones, saying that she’s “happy to share more if anyone has any questions about how I’m looking or feeling or where I am in my perimenopause process.”
“I didn’t lose 30lbs — I lost 50,” Schumer emphasized on social media, adding that she does not get Botox or filler. (Amy Schumer/Instagram)
What is Cushing’s syndrome?
Schumer previously revealed that she had been diagnosed with Cushing’s syndrome, a hormonal disorder that can cause extreme swelling, fatigue and potentially fatal complications.
Dr. Peter Balazs, a hormone and weight loss specialist in New Jersey, provided more details on the condition in an interview with Fox News Digital.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
“Cushing’s syndrome is caused by prolonged, high exposure to cortisol, which is your body’s main stress hormone,” he said. “Usually, the excess cortisol is a result of prolonged steroid use. We see this many times with patients who have some autoimmune disorder.”
Balazs said the “key” to Cushing’s syndrome is not just weight gain, but a “specific redistribution” of fat caused by too much cortisol.
Amy Schumer is photographed during a guest interview on The Tonight Show Starring Jimmy Fallon on Feb. 13, 2024 (left), and later seen walking through midtown New York City on Oct. 28, 2025 (right). (Todd Owyoung/NBC via Getty Images; Raymond Hall/GC Images/Getty Images)
Fat may be driven to the abdomen, chest, upper back (referred to as a “buffalo hump”) or face, sometimes considered “moon face,” the doctor said.
Cortisol also breaks down protein, which leads to a thinning in the arms and legs. “Weight gain can be tough, involuntary and hard to manage,” Balazs added.
CLICK HERE FOR MORE HEALTH STORIES
Cortisol stimulates “hunger centers” in the brain, raises blood sugar and promotes fat storage, especially deep belly fat, according to the doctor.
Cushing’s syndrome can also cause high blood pressure, bone loss and sometimes type 2 diabetes, per Mayo Clinic.
In addition to weight gain in certain areas, other symptoms may include pink or purple stretch marks on the stomach, hips, thighs, breasts and underarms, as well as acne, slow wound healing, and thin, frail skin that bruises easily.
With Cushing’s syndrome, fat may accumulate in the abdomen, chest, face or upper back (referred to as a “buffalo hump”). (iStock)
Women with Cushing’s syndrome often experience thick, dark hair on the face and body, as well as irregular periods. Symptoms among men can include a lower sex drive, reduced fertility and erectile dysfunction.
Mayo Clinic listed other potential symptoms, including extreme fatigue, muscle weakness, depression, anxiety, irritability, mood swings, trouble with concentration and memory, headache, sleeplessness, skin darkening and stunted growth in children.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Those with symptoms should contact their doctor immediately, especially if they are taking steroids to treat health issues like asthma, arthritis or inflammatory bowel disease, as these medications can exacerbate the condition.
The Mayo Clinic has reported that the “sooner treatment starts, the better the chances for recovery.”
“I’ve had plastic surgery over the years and I use [Mounjaro],” Schumer stated in a social media post. (George Frey/Bloomberg)
For patients like Schumer, weight loss is typically not the main goal, Balazs noted, but it is a “critical sign” of successful treatment.
“The primary goal is to normalize your high cortisol levels,” he said. “I believe Amy Schumer got treated first for her underlying problem. Once the cortisol is normalized, which is the most important step, there’s a role to use adjunct medications to decrease weight.”
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
Among GLP-1s, Mounjaro is an “excellent choice to decrease deep belly fat and increase insulin sensitivity of cells,” Balazs added.
Fox News Digital’s Stephanie Giang-Paunon contributed to this report.
Fox News Digital reached out to Schumer’s rep requesting comment.
NEWYou can now listen to Fox News articles!
VIRAL OUTBREAK — Measles surge leads to hundreds quarantined in U.S. county, officials say
SNOOZE AND LOSE — Popular sleep positions could be damaging your nerves, according to experts
The South Carolina Department of Public Health confirmed that 254 people are currently in quarantine in the upstate region. (iStock)
MUSCLE MATTERS — A new Ozempic-alternative diabetes pill burns fat without loss of body mass
50 POUNDS DOWN — “Effortless” weight loss was sparked by 3 simple habits, says “Top Model” winner
SIGN UP FOR OUR HEALTH NEWSLETTER
BEAUTY BEWARE — Cosmetic fillers can cause deadly complication, experts warn
‘AGING BACKWARDS’ — Simon Cowell touts controversial blood-rinsing procedure
Simon Cowell reveals he’s “aging backwards” with a controversial blood filtering treatment that removes and cleanses his blood before returning it to his body. (Ricky Vigil M/GC Images)
MEMORY THREAT — Alzheimer’s risk could rise with common condition affecting millions
LIKE WHAT YOU’RE READING? CLICK HERE FOR MORE HEALTH NEWS
FOOD FOR THOUGHT — Scientists reveal the one practice that could prevent dementia as you age
EPA wrongly found Detroit area safe for smog, judge rules in split decision
San Francisco’s Union Square sees holiday boost as Winter Walk begins
Dallas-Fort Worth might see some sunshine on Sunday. Will the coming week be cloudy?
Charging e-bike suspected in destructive Miami house fire
BU spoils Northeastern final game at Matthews Arena
Florida High School Football Rankings: Top 25 teams – Oct. 21
Cleary's 21 help Le Moyne down Central Connecticut State 69-64 in OT
How old is Bo Nix? What to know about Oregon quarterback ahead of 2024 NFL Draft
99th annual Pony Swim held in Virginia
Video: ‘It Didn’t Have to Happen This Way:’ U.Va. Faculty Call for Review of Police Response to Protests
Video: At Least Two Killed in Shooting at Brown University
FBI ousts reinstated whistleblower over unauthorized media talks, ‘poor judgment’
EU dismisses Russia’s lawsuit against Euroclear as ‘speculative’
Multiple people shot near Brown University, police say
Inside Minnesota’s $1B fraud: fake offices, phony firms and a scandal hiding in plain sight
-
Alaska1 week agoHowling Mat-Su winds leave thousands without power
-
Texas1 week agoTexas Tech football vs BYU live updates, start time, TV channel for Big 12 title
-
Ohio1 week agoWho do the Ohio State Buckeyes hire as the next offensive coordinator?
-
Washington5 days agoLIVE UPDATES: Mudslide, road closures across Western Washington
-
Iowa7 days agoMatt Campbell reportedly bringing longtime Iowa State staffer to Penn State as 1st hire
-
Miami, FL1 week agoUrban Meyer, Brady Quinn get in heated exchange during Alabama, Notre Dame, Miami CFP discussion
-
Cleveland, OH7 days agoMan shot, killed at downtown Cleveland nightclub: EMS
-
World6 days ago
Chiefs’ offensive line woes deepen as Wanya Morris exits with knee injury against Texans
