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Man dies hours after eating burger as researchers confirm fatal allergy

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Man dies hours after eating burger as researchers confirm fatal allergy

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A New Jersey man’s death is the first known to be linked to a tick-borne meat allergy, according to researchers at UVAHealth in Virginia.

The unidentified man, 47, reportedly died last summer, four hours after eating a hamburger and just two weeks after a similar episode triggered by steak.

With the summer episode, the man experienced severe abdominal pain, diarrhea and vomiting after eating the steak, a UVAHealth press release said.

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The incident was initially reported as “sudden unexplained death” until Dr. Thomas Platts-Mills of UVA Health determined the man suffered a fatal allergic reaction.

The findings were published in The Journal of Allergy and Clinical Immunology: In Practice.

A New Jersey man’s death is the first known to be linked to a tick-borne meat allergy, according to researchers at UVAHealth in Virginia. (iStock)

The allergy, alpha-gal syndrome (AGS) — also known as “red-meat allergy” or the “tick bite meat allergy” — is caused by the bite of the Lone Star tick, which is found primarily in Southeastern and Eastern states, according to the Centers for Disease Control and Prevention.

The tick’s saliva contains a sugar molecule called alpha-gal, which is injected into the body with the bite. This triggers allergies to certain types of red meat (primarily pork, beef, rabbit, lamb or venison) or products made from mammals (including cheese, milk, other dairy products and gelatin).

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When people eat any foods containing the allergens, they can experience serious allergy symptoms within a few hours, although some may only have mild reactions.

Symptoms may include rash, nausea and vomiting after eating beef, pork or lamb, according to researchers. Some may also experience itchy or scaly skin; swelling of the lips, face, tongue and throat; and wheezing or shortness of breath, according to Mayo Clinic.

The allergy, alpha-gal syndrome (AGS) — also known as “red-meat allergy” or the “tick bite meat allergy” — is caused by the bite of the Lone Star tick. (iStock)

Although fatal anaphylaxis has been noted as a rare risk in severe cases, the New Jersey man’s death was the first to be attributed to the allergy.

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Other factors that may have contributed to his severe reaction, according to Platts-Mills, include a beer he drank with his burger, his exposure to ragweed pollen and recent exercise.

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“The important information for the public is: First, that severe abdominal pain occurring three to five hours after eating beef, pork or lamb should be investigated as a possible episode of anaphylaxis; and, second, that tick bites that itch for more than a week or larvae of ticks often called ‘chiggers’ can induce or increase sensitization to mammalian-derived meat,” Platts-Mills, former chief of UVA Health’s Division of Asthma, Allergy and Clinical Immunology, said in the release.

“On the other hand, most individuals who have mild to moderate episodes of hives can control symptoms with an appropriate diet.”

The tick’s saliva contains a sugar molecule called alpha-gal, which is injected into the body with the bite. This triggers allergies to certain types of red meat. (iStock)

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A diagnosis of AGS requires antibody testing and a clinical exam. Many patients face a long road to diagnosis — an average of seven years, according to Dr. Johanna Salzer, CDC epidemiologist and author of a 2023 report on AGS.

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“And to get diagnosed, they have to have access to an allergist,” Salzer previously told Fox News Digital. “For many people, there are barriers to get that level of treatment.”

When someone is diagnosed with AGS, the person may have it for a lifetime.

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“However, for some people, if they remove the foods from their diet that can reactivate alpha-gal syndrome, over time, their antibody levels may drop,” the expert said.

There is no treatment or cure for AGS, though physicians can help patients manage their symptoms.

When people eat any foods containing the allergens, they can experience serious allergy symptoms within a few hours, although some may only have mild reactions. (iStock)

“There are a number of things [that] healthcare providers can provide to alleviate symptoms depending on the patients’ individual reactions,” Salzer said.

“Those with more severe reactions are administered EpiPens in case they go into anaphylactic shock.”

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Prevention tips

To protect against tick bites, Salzer recommends applying EPA-approved insect repellent, those containing DEET, picaridin, IR3535, Oil of Lemon Eucalyptus (OLE), para-menthane-diol (PMD) or 2-undecanone, whenever going into an area where tick bites are a possibility.

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Wearing long-sleeved shirts, long pants and socks and avoiding grassy, brushy and wooded areas can also help to prevent bites.

“When returning from an area that is known to have ticks, be sure to shower and do a very thorough check,” Salzer advised.

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Platts-Mills urged doctors and patients who live in areas where Lone Star ticks are common to be aware of the risk. 

“More specifically, if they have unexpected episodes of severe abdominal pain occurring several hours after eating mammalian meat, they should be investigated for possible sensitization to the oligosaccharide alpha-gal,” he added.

Fox News Digital reached out to the researchers for comment.

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.

That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.

The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.

LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS

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Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).

Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.

The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.

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“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”

Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.

HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS

In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.

For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)

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The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.

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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”

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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.

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Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)

“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.

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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.

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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs


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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

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Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

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The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

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New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities. 

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment. 

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

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