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Mail-order ketamine injections can be ‘extremely dangerous,’ warns Dr. Marc Siegel

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Mail-order ketamine injections can be ‘extremely dangerous,’ warns Dr. Marc Siegel

Ketamine has become increasingly popular for treating mental health disorders.

But some doctors and clinics have taken it to the next level by delivering the injectable doses to patients — who can then administer the drug unsupervised.

Fox News medical contributor Dr. Marc Siegel, who is also a clinical professor of medicine at NYU Langone Medical Center, spoke on “Fox & Friends” on Monday about the dangers of handing out ketamine.

KETAMINE THERAPY SHOWN EFFECTIVE IN TREATING SEVERE DEPRESSION IN VETERANS, STUDY FINDS

Ketamine was initially approved for use as an anesthetic in the U.S. in the 1970s, Siegel said.

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It was only indicated for treating depression within the last decade.

Ketamine was initially approved for use as an anesthetic in the U.S. in the 1970s and was only indicated for treating depression within the last decade. (iStock)

“It works for really severe depression by altering brain chemicals, but under the observation of a highly trained psychiatrist or anesthesiologist,” he said.

“The idea that it is now available with a little tele-visit, and then they mail it to you with a self-monitoring blood pressure kit, is extremely dangerous.” 

“It can make you really, really sick — and without observation, you could end up in the hospital.”

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The physician warned that ketamine can “knock you out, give you hallucinations, raise your blood pressure [or] lower your blood pressure.”

5 MYTHS ABOUT KETAMINE, THE DRUG TIED TO MATTHEW PERRY’S DEATH, ACCORDING TO DOCTORS

“[It can] make you really, really sick — and without observation, you could end up in the hospital,” he said.

In terms of “breaking a cycle of severe depression,” Siegel confirmed that ketamine is effective, “but not this way.”

Dr. Marc Siegel appeared on “Fox & Friends” on Monday, July 1, 2024, to discuss the risks of mail-order ketamine doses. (Fox News)

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Earlier this year, the University of Michigan released a study on the effects of ketamine in cases of severe or treatment-resistant depression among veterans.

Nearly half of all patients saw a “meaningful drop” in depression scores after six weeks of infusions, according to the analysis by the University of Michigan and VA Ann Arbor Healthcare System (VAAAHS).

About 25% of those in the study saw their depression score drop by half within six weeks of treatment, while 15% went into full remission.

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In response to the study, Dr. Justin Gerstner, psychiatrist and chief medical officer at Ellie Mental Health in Minnesota, told Fox News Digital that ketamine therapy has been “quite transformative for a lot of our clients.”

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While patients get the benefit of not having to take medication every day, Gerstner noted that there isn’t much regulation surrounding how ketamine treatments are administered.

Although ketamine has shown to be effective against severe depression, doctors do not recommend that patients use it without medical supervision. (Getty Images)

“The field is wide open, and it’s a little bit like the Wild West,” he said. 

“This is a really powerful medication, and the way it’s used can vary quite drastically.”

The Alcohol and Drug Foundation (ADF) describes ketamine as a “dissociative drug,” which means it causes people to feel “separated or detached” from their bodies or physical surroundings.

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For more Health articles, visit www.foxnews.com/health.

While it is also used illegally as a recreational drug, experts say ketamine is generally not dangerous when used as prescribed.

Fox News Digital’s Melissa Rudy contributed to this report.

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The Best Time To Take Turmeric for Weight Loss and How To Maximize Results

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Doctor reveals what 30 days without alcohol does to the brain and body amid Dry January

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Doctor reveals what 30 days without alcohol does to the brain and body amid Dry January

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After a season of bingeing and drinking, your body may feel like it needs a break from the party.

Dry January — a modern trend that challenges people to abstain from drinking for the first month of the year — has become a popular way to “detox” from the holidays and start the new year on a healthy note.

Research has linked alcohol to a variety of health conditions, ranging from hangovers to higher cancer risk.

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In a recent podcast episode of “The Dr. Mark Hyman Show,” Dr. Mark Hyman, chief medical officer of Function Health, shared how 30 days of not drinking alcohol can transform health.

Hyman, who is based in Massachusetts, called Dry January a “powerful way to see in real time how alcohol affects nearly every system of your body and how quickly those systems can recover.”

Dry January has become a popular way to “detox” from the holidays and start the new year on a healthy note. (iStock)

Alcohol’s toll on the brain and body

Hyman acknowledged that most people drink to feel happier and more comfortable in social situations. This effect is caused by the main ingredient in alcohol, called ethanol, which can also have toxic effects.

Instead of stimulating the brain, alcohol slows it down and loosens inhibitions. “You feel more relaxed, more social, more confident, maybe you feel a little euphoric,” Hyman said.

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Alcohol’s effect on the brain can also lead to poorer decisions and slower reflexes, the doctor cautioned.

Drinking alcohol can cause cognitive decline and brain fog, experts warn. (iStock)

Drinking also impacts the prefrontal cortex of the brain, which Hyman described as “the adult in the room,” responsible for judgment, planning and restraint. “It goes offline early in drinking, which explains why people feel freer or act impulsively when they drink,” he said.

Even moderate drinking can cause metabolic stress, inflammation, impaired detoxification and hormonal shifts, Hyman said, which can impact nearly every organ system in the body.

POPULAR WEIGHT-LOSS DRUGS COULD TAKE THE EDGE OFF YOUR ALCOHOL BUZZ, STUDY FINDS

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Alcohol consumption has also been linked to an increased risk of cancer, metabolic dysfunction, gut microbiome disturbances and mitochondrial toxins.

It can also prevent the body from falling into REM sleep, which is the deep rest recovery period when the immune system cleans out the day’s toxins, according to Hyman.

Alcohol can impact deep rest and mental health, according to experts. (iStock)

Memory loss, cognitive decline, anxiety, sleep disruption, dementia and cardiovascular disease are all known risks of long-term alcohol use, as well as liver complications like fatty liver disease.

“Bottom line, alcohol taxes every major system in your body, especially your liver, your brain, your gut, your hormones,” Hyman said.

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The effects of 30 days with no alcohol

The first week after your last drink, the body begins to detoxify and reset, according to Hyman. Blood sugar and cortisol stress hormones level out, and the liver begins to process a “backlog of toxins.” The body also re-hydrates and re-energizes.

The first 30 days with no alcohol allows the body to balance itself out. (iStock)

The second week, the gut and brain will begin to re-balance, as hormones like serotonin and dopamine stabilize, gut inflammation drops and the microbiome begins to heal. Cravings for sugar and alcohol will wane and mental clarity returns, the doctor said.

Week three is marked by further decreases in inflammation, fatty liver and blood pressure. This can be noticeable in the skin, as puffiness and redness are reduced. Mood also begins to stabilize, with lower anxiety levels.

DOCTORS REVEAL WHY ALCOHOL CAUSES ‘BOOZE BUTT’ AND HOW TO PREVENT IT ON NEW YEAR’S

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In week four, the body experiences additional metabolic and immune benefits, Hyman shared, including more insulin sensitivity, which makes it easier to lose weight.

“You have a stronger immune response. You’re not getting sick as much. You have better deep sleep, balanced hormones, especially cortisol and testosterone,” he said. “And you see a big change in energy, confidence and focus.”

Abstaining from alcohol can help restore energy, according to experts. (iStock)

Dr. Pinchieh Chiang, a clinician at Circle Medical in San Francisco, said that Dry January isn’t a “detox,” but rather provides “feedback” from the body.

“It gives the body time to show people how it feels without alcohol. For many, that insight alone changes their relationship with drinking,” she said. “The biggest surprise isn’t what people give up, it’s how much better they feel.”

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HIGHER STROKE RISK LINKED TO CONSUMING CERTAIN AMOUNT OF ALCOHOL, STUDY FINDS

The doctor confirmed that the first few days of not drinking may feel harder than expected, sometimes causing restlessness, cravings or disrupted sleep, but Dry January can ultimately change drinking habits for the remainder of the year.

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After a full year without alcohol, Chiang noted that health improvements are more profound. “We see sustained improvements in blood pressure, liver function and inflammation,” she said. “Those changes directly affect long-term heart disease and stroke risk.”

The risks of ‘all or nothing’

Some experts warn that adopting the Dry January trend could strengthen the urge to drink more in the other months, noting that some drinkers may find more success by slowly consuming fewer drinks per week.

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Thomas Stopka, Ph.D., an epidemiologist and professor in the public health and community medicine department at Tufts University School of Medicine in Massachusetts, shared in a Futurity report that for some people, “damp January” may be more suitable.

One expert warned that not all drinkers should quit “cold turkey,” as it could lead to severe withdrawals. (iStock)

“Dry January is well-intentioned, and it may work really well for the people who can stick to it, maybe even beyond January,” he said. “Other people may be more inclined to cut down on alcohol consumption rather than quit drinking completely for the month.”

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Stopka noted that successful harm-reduction approaches “aim to be judgment free.”

“Substance use disorder is a disease,” he said. “It takes time to treat the disease and to stay connected to the continuum of care — from prevention to treatment initiation to sustained therapy, whether through medication, self-help, or individual therapy or group support.”

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Those struggling with signs of alcohol use disorder should consult a medical professional for personalized guidance.

Fox News Digital reached out to several alcohol industry associations requesting comment.

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The Best Weight Loss Medications and Supplements in 2026

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The Best Weight Loss Medications and Supplements in 2026


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