Health
Hair loss and prostate medication could also reduce heart disease risk, study finds
A drug that has long been used to treat two common men’s health conditions could have some unexpected benefits.
Finasteride — more commonly known as Propecia or Proscar — has treated male pattern baldness and enlarged prostate in millions of men.
In a recent study, researchers from the University of Illinois Urbana-Champaign have also linked the “miracle drug” to cholesterol-lowering effects and reduced heart disease risk.
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The findings, published in the Journal of Lipid Research, showed lower cholesterol levels among men who took the drug — on average, 30 points less than men who were not on the medication.
The data was initially collected as part of the National Health and Nutrition Examination Survey between 2009 and 2016.
A drug that has long been used to treat two common men’s health conditions could have some unexpected benefits. (iStock)
Then, in a study of mice, use of the drug for 12 weeks — along with a high-fat, high-cholesterol “Western” diet — was linked to reduced cholesterol, slower buildup of plaque in the arteries and reduced liver inflammation, among other benefits.
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“The most surprising finding was the human data,” lead study author Jaume Amengual, assistant professor in the Department of Food Science and Human Nutrition and the Division of Nutritional Sciences at the University of Illinois, told Fox News Digital.
“When we observed the association with finasteride and plasma lipids, we decided to do our mouse study.”
Drug’s benefits and side effects
As a hair loss treatment, finasteride works by blocking a protein found in hair follicles — and as an enlarged prostate treatment, the drug blocks the prostate gland that activates testosterone.
Atherosclerosis, which occurs when cholesterol plaques build up in the arteries and increase the risk of heart attack and stroke, is most prevalent among men.
As a hair loss treatment, finasteride works by blocking a protein found in hair follicles. (iStock)
Some experts have linked the male hormone testosterone to the heart condition.
The potential hormonal effect prompted the researchers to explore whether the medication could also reduce heart disease risk, Amengual said.
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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, was not involved in the study but commented on the implications of finasteride.
“It stops testosterone from turning into dihydrotestosterone and thereby stops hair loss and also shrinks the prostate by 25%,” he said.
Side effects can include depression, anxiety and impotence, the doctor added.
In response to the drug being found to lower cholesterol and decrease heart disease risk, a doctor called for more research to confirm the findings. (iStock)
Dr. Brett Osborn, a Florida neurologist and longevity expert who was also not involved in the study, offered his insights on the uses and risks associated with the drug.
“Finasteride in normal dosages — 1 to 5 mg daily, depending upon the indication — has intolerable side effects in many,” he said.
“Finasteride in normal dosages has intolerable side effects in many.”
The drug works by lowering levels of DHT (dihydrotestosterone) in order to have the desired effect on the prostate gland and hair follicles, he said, “but it can also strip a man of his energy, virility, libido and motivation.”
Study limitations and next steps
The study did have some limitations, the researchers noted.
Out of nearly 4,800 total participants, only 155 were finasteride users, all of whom were men over 50. The survey also did not determine the duration or amount of the doses.
As an enlarged prostate treatment, finasteride blocks the prostate gland that activates testosterone. (iStock)
“We also did not examine the effects of finasteride in women or female mice,” Amengual said.
“However, this drug is not prescribed for women, as it could be dangerous during pregnancy.”
“This drug could be another tool in the fight against cardiovascular diseases.”
The next step is to track cholesterol levels of patients taking finasteride or to launch a clinical trial to confirm the link.
“There is still so much to discover on how finasteride works in our body,” Amengual noted. “But based on our findings, this drug could be another tool in the fight against cardiovascular diseases.”
The drug works by lowering levels of DHT (dihydrotestosterone) in order to have the desired effect on the prostate gland and hair follicles, which can cause side effects in some men, a doctor noted. (iStock)
In response to the drug being found to lower cholesterol and decrease heart disease risk, Siegel also called for more research.
“Much larger studies are needed in humans to confirm these findings before you would ever consider using this drug for cardioprevention,” he said.
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“It may end up being useful for this purpose in the elderly, who are at higher risk of heart attacks and strokes, as an add-on statin therapy.”
In addition to the study’s small size, Osborn noted that it was performed retrospectively — “meaning there was no control group(s), and that random effects, unbeknownst to the researchers, may have swayed the results in one direction,” he told Fox News Digital.
Dr. Marc Siegel, left, and Dr. Brett Osborn both shared insights on finasteride’s uses and side effects. (Dr. Marc Siegel | Dr. Brett Osborn)
“That said, the authors’ observations are interesting and demand further investigation,” Osborn went on.
“After all, lipid-lowering agents are one of the mainstays of cardiovascular risk reduction — and most Americans die vascular deaths.”
This study doesn’t mean that every male should start taking finasteride, Osborn cautioned.
Instead, he recommends getting regular exercise, increasing daily fiber intake to 25 grams and taking high doses of omega-3 fatty acids to reduce cardiovascular risk.
“For now, skip the finasteride as a lipid-lowering agent,” he advised. “As it stands now, the juice isn’t worth the squeeze.”
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Health
Experts reveal why ‘nonnamaxxing’ trend may improve mental, physical health
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The key to feeling better in a fast, overstimulated world might be surprisingly simple: Live a little more like your grandparents.
A growing social media trend, dubbed “nonnamaxxing,” draws inspiration from the slower, more intentional rhythms associated with an Italian grandmother.
The lifestyle is often linked to activities like preparing home-cooked meals, spending time outdoors and making meaningful connections.
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“Nonnamaxxing is a 2026 trend that embraces the slower, more intentional lifestyle of an Italian grandmother (a Nonna). Think cooking from scratch, long family meals, daily walks, gardening and less screen time,” Erin Palinski-Wade, a New Jersey-based registered dietitian, told Fox News Digital.
Nonnamaxxing, derived from the name for an Italian grandmother, is a trend that incorporates lifestyle habits hundreds of years in the making. (iStock)
Stepping away from screens and toward real-world interaction can have measurable benefits, according to California-based psychotherapist Laurie Singer.
“We know that interacting with others in person, rather than spending time on screens, significantly improves mental health,” she told Fox News Digital, adding that social media often fuels comparison and lowers self-esteem.
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Living more like previous generations isn’t purely driven by nostalgia. Cooking meals from scratch, for example, has been linked to better nutrition and more mindful eating patterns.
Adopting traditional mealtime habits can improve diet quality and support both physical and mental health, especially when meals are shared regularly with others, Palinski-Wade noted.
One longevity expert stresses that staying healthy isn’t just about food — it’s also about joy and community. (iStock)
There’s also a psychological benefit to slowing down and focusing on one task at a time. Anxiety often stems from unfinished or avoided tasks, Singer noted, and engaging in hands-on activities can counteract that.
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“Nonnamaxxing encourages us to be present around a task, like gardening, baking or knitting, or just taking a mindful walk, that delivers something ‘real,’” she said.
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Palinski-Wade cautions against turning the trend into another source of pressure, noting that a traditional “nonna” lifestyle often assumes a different pace of life.
The key, she said, is adapting the mindset, not replicating it perfectly.
Nonnamaxxing, derived from the name for an Italian grandmother, is a trend that incorporates lifestyle habits hundreds of years in the making. (iStock)
The goal is to reintroduce small, intentional moments that make you feel better.
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That might mean prioritizing a few shared meals each week, taking a walk without your phone or setting aside time for a simple hobby, the expert recommended.
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Singer added, “Having a positive place to escape to, through whatever activities speak to us and make us happy, isn’t generational – it’s human.”
Health
Loneliness may be silently eroding your memory, new research reveals
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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
Health
Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day
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