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Common diabetes drug may help preserve eyesight as people age

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Common diabetes drug may help preserve eyesight as people age

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A common medication for diabetes may slow down age-related vision loss, according to new research.

People with diabetes who were over the age of 55 and taking metformin — a prescription drug most commonly used to treat type 2 diabetes — were 37% less likely to develop intermediate age-related macular degeneration (AMD) over five years compared to those not taking it.

Researchers at the University of Liverpool used eye pictures from 2,000 people who received routine diabetic eye disease screenings over the course of five years.

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Next, they assessed whether AMD was present in the photos and how severe each case was, before comparing the differences between people taking metformin and those who did not take it, according to a press release.

Age-related macular degeneration, often called AMD, is one of the leading causes of irreversible blindness in older adults. (PeopleImages/Getty Images)

They also adjusted for factors that could potentially skew the results, such as age, sex and how long they’d had diabetes.

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“Most people who suffer from AMD have no treatment, so this is a great breakthrough in our search for new treatments,” said Nick Bear, an ophthalmologist at the University of Liverpool in the U.K., who led the research.

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“What we need to do now is test metformin as a treatment for AMD in a clinical trial. Metformin has the potential to save many people’s sight,” he added.

“Metformin has the potential to save many people’s sight,” the researchers said. (iStock)

While the results are promising, researchers noted that the study was observational, meaning it shows a link between the drug and eye health, but does not prove metformin was the direct cause of the improvement.

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The study also focused only on people with diabetes. It is unclear whether the drug would have the same effect on people without the condition.

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Additionally, the researchers did not have data on the specific doses of metformin patients took or how strictly they followed their prescriptions.

Researchers noted that the study was observational, meaning it shows a link between the drug and eye health, but does not prove metformin was the direct cause of the improvement. (iStock)

Metformin is an off-patent, low-cost drug already widely used to manage blood sugar, according to Mayo Clinic.

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Scientists believe its anti-inflammatory and anti-aging properties may help protect the retina.

Mayo Clinic says metformin is generally safe, but can cause digestive side effects and vitamin B12 deficiency in some patients.

Health

What’s healthier to drink: cold or hot water? Here’s what an expert says

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What’s healthier to drink: cold or hot water? Here’s what an expert says

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A viral wellness trend asks a simple question — is warm or cold water healthier? — but the science behind it is more nuanced.

Previous research shows that food and beverage temperature has a measurable effect on things like anxiety and gut discomfort.

One of the most long-standing health claims is that ice-cold water boosts calorie burn by forcing the body to heat it up. While this is grounded in science, the actual impact may be minimal.

Ultimately, experts say, the health impact of water temperature depends on the goal — weight loss, athletic performance, digestion or comfort.

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Does cold water boost weight loss?

“As per research, in the 90 minutes after consuming cold or room temperature water, energy expenditure increases minimally by 2.9% (cold water) and 2.3% (room temperature),” Tanya Freirich, a registered dietitian and diabetes expert in North Carolina, told Fox News Digital.

Extra water may suppress the appetite or may play a part in energy production and expenditure, experts say. (iStock)

While the body does expend energy to warm up cold water, Freirich noted that it’s “not significant enough to make it worthwhile” for weight loss. Hot water doesn’t exactly melt fat, however, she added.

For those looking to lose or manage weight, Freirich suggests focusing on “how much” rather than “how cold.” She pointed to research involving overweight women who added an extra 1.5 liters of water to their daily intake. Over eight weeks, the participants saw measurable weight loss.

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“The extra water may suppress the appetite or may play a part in energy production and expenditure,” Freirich said. The temperature of drinking water should not affect how well the body utilizes nutrients, she added, noting that more research is needed.

For those exercising in heat and humidity, the goal should be to rehydrate without excessive fluid loss through sweat. Research on thermoregulation suggests there is an ideal water temperature for athletes.

The temperature of drinking water should not affect how well the body utilizes nutrients, according to an expert. (iStock)

While drinking water can trigger sweating as the body regulates its temperature, 60.8 degrees Fahrenheit was associated with the least amount of perspiration.

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“Cool, but not cold,” Freirich emphasized. Drinking water in this specific range helps the body rehydrate efficiently without causing gastrointestinal distress.

Warm water and digestion

There are several reasons someone might opt for warm water, including its effect on relaxation and digestion. Studies have found that warmer liquids can accelerate gastric emptying, effectively waking up the gut.

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The benefits may be mental as well. Freirich points to research showing that hot black tea leads to lower levels of cortisol — the body’s primary stress hormone — and greater subjective relaxation after stressful tasks.

The preference for warm water often stems from its effect on the rest and digestion. Studies have found that warmer liquids can accelerate gastric emptying, effectively waking up the gut. (iStock)

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Medical triggers

Freirich warns that very cold water can cause difficulty for those with swallowing disorders, or can trigger migraines and “brain freeze” in people with sensitive nerves.

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Furthermore, those with irritable bowel syndrome (IBS) may find that ice-cold drinks trigger digestive discomfort.

Ultimately, the best temperature is the one that encourages people to drink, the dietitian said. The general recommendation for adults is to consume seven to eight glasses of water per day.

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“Most importantly, it is important for everyone to stay adequately hydrated,” Freirich said.

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Alarming report reveals what’s driving deadly cancer surge in young adults

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Alarming report reveals what’s driving deadly cancer surge in young adults

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→ Origin of deadly cancer affecting young adults revealed in alarming report

→ Scientists make startling discovery when examining prostate cancer tissue

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Colorectal cancer rates are surging among younger adults, with those 65 and under now comprising 45% of new diagnoses compared to 27% in 1995. (iStock)

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176 Lbs—Gone! Why One Woman’s Gentle Weight-Loss Tips Really Work

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176 Lbs—Gone! Why One Woman’s Gentle Weight-Loss Tips Really Work


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Cheri’s Gentle Weight-Loss Approach Helped Her Lose Big | Woman’s World




















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