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Colorectal cancer is now leading cause of death among young adults with cancer: new report

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Colorectal cancer is now leading cause of death among young adults with cancer: new report

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Colorectal cancer is now among the leading causes of cancer deaths for young adults, according to a new report from the American Cancer Society (ACS).

Each year, the ACS compiles data on the numbers of new cancer cases and deaths in the U.S., which are published in CA: A Cancer Journal for Clinicians.

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Colorectal cancer has steadily grown among adults younger than 50, the report noted.

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In the late 1990s, it was the fourth-leading cause of cancer death in that age group. 

As of 2024, it ranks as the leading cause of cancer deaths in men and the second leading cause in women.

Colorectal cancer is now among the leading causes of cancer deaths for young adults, according to a report from the American Cancer Society (ACS). (iStock)

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Dr. Aparna Parikh, medical director of the Center for Young Adult Colorectal Cancer at the Mass General Cancer Center, who is not affiliated with the ACS, said she is “alarmed but not surprised” by the rising colorectal rates among young people — and particularly by the fact that colon cancer is now the leading cause of cancer death for men under 50. 

The colorectal cancer research community has been working to determine why rates are rising among young adults, Parikh said.

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“We don’t entirely understand why yet, but it seems to be an interplay of a person’s risk factors, overall makeup and early exposures,” she told Fox News Digital in an email.

“The exposures include dietary exposures, environmental exposures and possible antibiotic exposures, as well as lifestyle factors in the right host,” Parikh added. 

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“Screening at [age] 45 is [the] standard of care, and the gold standard is colonoscopy.”

There are many people who have healthy lifestyle habits and no apparent risk factors who go on to develop colorectal cancer, the doctor noted — “and then there are plenty of patients who have less than ideal habits.”

She said, “It really is an interplay between the right person and the right exposures.”

As of 2024, colorectal cancer ranks as the leading cause of cancer deaths in men. (iStock)

Some primary risk factors include family history, obesity, smoking, heavy alcohol, a diet high in red and processed meats, inflammatory bowel disease and a personal history or family history of polyps, according to Parikh.

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To reduce cases in younger patients, the doctor stressed the importance of raising public awareness of the disease around recognizing symptoms early.

CANCER RISK COULD INCREASE WITH CONSUMPTION OF CERTAIN FOODS AND DRINKS, STUDY FINDS

She also recommended certain healthy lifestyle habits, including avoiding or limiting red meat, not smoking, exercising regularly and adopting a more Mediterranean-based diet. 

Early screening is also important, Parikh noted.

“Screening at [age] 45 is [the] standard of care, and the gold standard is colonoscopy — but there are also stool-based tests that are appropriate,” she said. 

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“If you are having any symptoms like weight loss, blood in stool, anemia or change in bowel habits, you should go straight to colonoscopy.”

Some primary risk factors for colorectal cancer include family history, obesity, smoking, heavy alcohol, a diet high in red and processed meats, inflammatory bowel disease and a personal history or family history of polyps, according to a cancer doctor. (iStock)

Overall, the ACS expects that over 2 million new cancer cases and 611,720 cancer deaths will occur in the U.S. in 2024.

Although overall cancer mortality has been dropping — likely as a result of earlier detection, improved treatments and healthy lifestyle behaviors — the report stated that several types of cancers have increased in prevalence.

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In addition to colorectal cancer, cervical cancer also rose 1% to 2% annually among adults between 30 and 44 years of age.

Among all age groups, cancer rates rose 0.6% to 1% annually for breast, pancreas and uterine corpus cancers, and 2% to 3% annually for prostate, liver (female), kidney and human papillomavirus-associated oral cancers and for melanoma, the report stated.

The data in the ACS report was drawn from central cancer registries and mortality data collected by the National Center for Health Statistics.

Fox News Digital reached out to the ACS for additional comment.

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5 winter-weather essentials to protect skin health in dangerously cold temperatures

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5 winter-weather essentials to protect skin health in dangerously cold temperatures

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As winter weather moves in, cozy essentials like scarves, plush throws and heated bedding become everyday comforts. 

But dermatologists caution that these cold-weather favorites can secretly undermine skin health — trapping sweat and bacteria, causing irritation and exposing the skin to excess heat. 

Choosing the right materials for wellness — and using them safely — can make a big difference. 

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Here are five winter must-haves and gift ideas, with expert tips on how to keep skin healthy and happy while staying warm this season.

Soft scarf, $19.99, Amazon.com

Scarves made of natural fiber, like this one that is 100% cotton, may help if you’re prone to irritation. (Amazon)

A soft scarf is a staple for cold days and an easy way to elevate a winter outfit.

Yet, if breakouts are appearing along the neck, jawline or chest, that favorite accessory may be part of the problem.

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“You should wash your scarf as often as your clothes to prevent breakouts,” Annabelle Taurua, a beauty expert at Fresha, a beauty and wellness booking platform headquartered in London, told Fox News Digital.

Cotton is a better choice than polyester, she also noted, as it’s more breathable and allows sweat to evaporate.

Fluffy blankets, $28.97, Potterybarn.com

Fluffy blankets make for perfect cozy days at home, but their soft fibers can trap sweat, oils and dead skin — which can clog pores and encourage bacteria growth. (Pottery Barn)

Fluffy blankets make for perfect cozy days at home, but their soft fibers can trap sweat, oils and dead skin, which can clog pores and encourage bacteria growth. 

Rough textures or infrequent washing can also irritate sensitive skin and worsen breakouts.

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“Regularly wash your blankets, especially those made from synthetic or fluffy materials, to remove built-up oils and dirt,” Taurua advised.

She recommended breathable materials like cotton or linen, as well as hypoallergenic options for anyone prone to irritation.

Good set of sheets, $49.99, Amazon.com

Much like scarves, natural fibers are the way to go for your linens to avoid irritation. (iStock)

Cold weather makes lingering in bed especially tempting, but lying on unwashed bedding can worsen acne.

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Pillowcases and sheets quickly collect oil, bacteria and dead skin cells, which transfer directly onto the face.

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“Washing bedding frequently is important,” Taurua said. “You should aim to change and wash your pillowcases every two to three days and your sheets at least once a week.”

Heated blanket, $33.99, Walmart.com

Heated blankets are a great way to stay warm during the winter. (Walmart)

When using a heated blanket, start with the lowest heat setting and limit use, said Taurua.

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“Once you’re warm, switch to a regular blanket,” she advised.

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She also said it’s best to avoid direct contact for long periods to reduce irritation.

Hot water bottle, $12.99, Amazon.com

A traditional winter staple, hot water bottles offer quick comfort — but they come with risks similar to heated blankets, including burns, scalding and long-term heat-related skin damage.

Hot water bottles should never be filled with boiling water, experts advise. (Amazon)

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“Never fill a hot water bottle with boiling water,” Taurua said. 

“Only use hot, not boiling, water, and fill it to a maximum of two-thirds.”

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She recommended wrapping the bottle in a towel or cover to avoid direct skin contact and limiting use to around 20 minutes.

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Foods and Drinks That Help With Bloating: Flatten Your Belly in Days

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What to know about Cushing’s syndrome, which led to Amy Schumer’s dramatic weight loss

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What to know about Cushing’s syndrome, which led to Amy Schumer’s dramatic weight loss

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Comedian Amy Schumer, 44, has recently come clean about her struggle with Cushing’s syndrome, leading to a dramatic weight loss.

Schumer’s transformation has sparked conversation online, to which she responded in a now-deleted Instagram post that shut down speculation about cosmetic enhancements.

“I didn’t lose 30lbs — I lost 50,” she emphasized on social media, adding that she does not get Botox or filler.

AMY SCHUMER DROPPED 50 POUNDS TO BATTLE DISEASE THAT ‘CAN KILL YOU’ IF UNTREATED

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Schumer doubled down that her weight loss was not about her appearance, but about staying alive.

“Not to look hot, which does feel fun and temporary,” she said. “I did it to survive. I had a disease that makes your face extremely puffy that can kill you, but the internet caught it and that disease has cleared.”

Amy Schumer attends Variety’s 2024 Power of Women: New York event on May 2, 2024, in New York City on the left. On the right, Schumer later poses for a photo posted to Instagram after her weight loss. (Marleen Moise/WireImage; Amy Schumer/Instagram)

“Sorry for whatever feeling it’s giving you that I lost that weight,” she added. “I’ve had plastic surgery over the years and I use [Mounjaro]. Sorry to anyone they let down. I’m pain free. I can [play] tag with my son.”

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The actress also addressed her shifting hormones, saying that she’s “happy to share more if anyone has any questions about how I’m looking or feeling or where I am in my perimenopause process.”

“I didn’t lose 30lbs — I lost 50,” Schumer emphasized on social media, adding that she does not get Botox or filler. (Amy Schumer/Instagram)

What is Cushing’s syndrome?

Schumer previously revealed that she had been diagnosed with Cushing’s syndrome, a hormonal disorder that can cause extreme swelling, fatigue and potentially fatal complications.

Dr. Peter Balazs, a hormone and weight loss specialist in New Jersey, provided more details on the condition in an interview with Fox News Digital.

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“Cushing’s syndrome is caused by prolonged, high exposure to cortisol, which is your body’s main stress hormone,” he said. “Usually, the excess cortisol is a result of prolonged steroid use. We see this many times with patients who have some autoimmune disorder.”

Balazs said the “key” to Cushing’s syndrome is not just weight gain, but a “specific redistribution” of fat caused by too much cortisol.

Amy Schumer is photographed during a guest interview on The Tonight Show Starring Jimmy Fallon on Feb. 13, 2024 (left), and later seen walking through midtown New York City on Oct. 28, 2025 (right). (Todd Owyoung/NBC via Getty Images; Raymond Hall/GC Images/Getty Images)

Fat may be driven to the abdomen, chest, upper back (referred to as a “buffalo hump”) or face, sometimes considered “moon face,” the doctor said.

Cortisol also breaks down protein, which leads to a thinning in the arms and legs. “Weight gain can be tough, involuntary and hard to manage,” Balazs added.

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Cortisol stimulates “hunger centers” in the brain, raises blood sugar and promotes fat storage, especially deep belly fat, according to the doctor.

Cushing’s syndrome can also cause high blood pressure, bone loss and sometimes type 2 diabetes, per Mayo Clinic.

In addition to weight gain in certain areas, other symptoms may include pink or purple stretch marks on the stomach, hips, thighs, breasts and underarms, as well as acne, slow wound healing, and thin, frail skin that bruises easily.

With Cushing’s syndrome, fat may accumulate in the abdomen, chest, face or upper back (referred to as a “buffalo hump”). (iStock)

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Women with Cushing’s syndrome often experience thick, dark hair on the face and body, as well as irregular periods. Symptoms among men can include a lower sex drive, reduced fertility and erectile dysfunction.

Mayo Clinic listed other potential symptoms, including extreme fatigue, muscle weakness, depression, anxiety, irritability, mood swings, trouble with concentration and memory, headache, sleeplessness, skin darkening and stunted growth in children.

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Those with symptoms should contact their doctor immediately, especially if they are taking steroids to treat health issues like asthma, arthritis or inflammatory bowel disease, as these medications can exacerbate the condition.

The Mayo Clinic has reported that the “sooner treatment starts, the better the chances for recovery.”

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“I’ve had plastic surgery over the years and I use [Mounjaro],” Schumer stated in a social media post. (George Frey/Bloomberg)

For patients like Schumer, weight loss is typically not the main goal, Balazs noted, but it is a “critical sign” of successful treatment.

“The primary goal is to normalize your high cortisol levels,” he said. “I believe Amy Schumer got treated first for her underlying problem. Once the cortisol is normalized, which is the most important step, there’s a role to use adjunct medications to decrease weight.”

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Among GLP-1s, Mounjaro is an “excellent choice to decrease deep belly fat and increase insulin sensitivity of cells,” Balazs added.

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Fox News Digital’s Stephanie Giang-Paunon contributed to this report.

Fox News Digital reached out to Schumer’s rep requesting comment.

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