Health
Cat owners could be at higher risk of schizophrenia, study suggests, but more research needed
Cuddling with a cat or kitten might seem therapeutic, but a new study suggests contact with these animals could have adverse mental health effects down the road.
Research published in Schizophrenia Bulletin found that people who are exposed to cats may have more than double the chances of developing schizophrenia and other similar mental disorders later in life.
Australian researchers from the University of Queensland conducted a systematic review of 17 studies performed in 11 countries between Jan. 1, 1980, and May 30, 2023.
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The study data was pulled from several databases, including Medline, Embase, CINAHL, Web of Science and other publications.
All the studies focused on participants who owned cats in their first 25 years of life and experienced schizophrenia-related outcomes, according to the researchers.
A new study suggests that being exposed to cats early in life could have adverse mental health effects down the road. (iStock)
Schizophrenia is a mental illness that affects a person’s thoughts, behaviors and feelings, as defined by the National Institute of Mental Health.
Psychotic symptoms can include hallucinations, delusions and thought disorders.
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Those with the disorder may also experience cognitive challenges, loss of motivation, withdrawal from social activities, difficulty showing emotions and an overall lack of functioning.
“Based on past studies, there is evidence linking cat ownership and an increased risk of subsequent schizophrenia,” study author Dr. John McGrath, a psychiatrist at Queensland Brain Institute at the University of Queensland, St Lucia, Australia, told Fox News Digital.
“We had an open mind, and we reported the published findings.”
Research published in Schizophrenia Bulletin found that people who own cats may have more than double the chance of developing schizophrenia and other similar mental disorders later in life. (iStock)
Previous research linking cat exposure to schizophrenia risk has focused on Toxoplasma gondii (T. gondii), a parasite that can cause a feline disease called toxoplasmosis.
Separate studies have identified a “modest to large association” between toxoplasmosis and schizophrenia.
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The study did have some limitations, McGrath acknowledged.
“While observational epidemiology cannot prove this link, this topic warrants further, more detailed research,” he said.
“I was disappointed that there were not more highly quality — i.e., more rigorous — studies in our review.”
“Schizophrenia is an incredibly complex disorder, and this study identifies one potential risk factor that needs to be understood in a broader context.”
Schizophrenia is a “poorly understood group of disorders,” McGrath noted.
“We need to invest in more research that looks at potential risk factors. There is much work to be done.”
‘No need to panic’
Dr. Zachary Ginder, a psychological consultant and doctor of clinical psychology at Pine Siskin Consulting, LLC in Riverside, California, was not involved in the study but commented on the findings.
Schizophrenia is a mental illness that affects a person’s thoughts, behaviors and feelings. Psychotic symptoms can include hallucinations, delusions and thought disorders. (iStock)
“It is important to keep a level head in consideration of these findings, and there is no need to panic if you own a cat and have children or are thinking about starting a family,” Ginder told Fox News Digital.
“Schizophrenia is an incredibly complex disorder, and this study identifies one potential risk factor that needs to be understood in a broader context. It would likely be premature to make strong recommendations about cat ownership solely based on these findings.”
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Although a relationship has been established between early-life cat exposure and schizophrenia, Ginder emphasized that this does not necessarily indicate that exposure causes the disorder.
“A lot more research” is needed to better understand these relationships — “accounting for a myriad of potential confounding factors and exploring underlying biological mechanisms,” said one psychological consultant and doctor of clinical psychology. (iStock)
“There is a lot that we still don’t know, and it is important to highlight that not all people who are exposed to cats or infected with the parasite develop mental health issues, and not all people with schizophrenia have had cat exposure,” he told Fox News Digital.
“While this parasite may play a role, it’s likely part of a complex interplay of genetic and environmental factors.”
Ginder echoed the researchers’ comments that “a lot more research” is needed to better understand these relationships — “accounting for a myriad of potential confounding factors and exploring underlying biological mechanisms.”
“These findings just give us another piece of an incredibly complex puzzle.”
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Brain aging may accelerate after cancer treatment, study suggests
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Surviving cancer as a child or young adult may have a lasting impact on aging, new research suggests.
Researchers at the University of Rochester Medical Center looked at whether life-saving treatments, like chemotherapy and radiation, could speed up biological aging.
They also aimed to determine whether this age acceleration was linked to cognitive issues related to memory, focus and learning.
The team analyzed blood samples from a group of 1,400 long-term survivors treated at St. Jude Children’s Research Hospital, using epigenetic clocks — tools that estimate biological age by examining chemical tags on DNA.
Biological age is determined based on damage the cells accumulate over time, versus chronological age, which is measured by how long someone has been alive, according to scientists.
Biological age is determined based on the damage cells accumulate over time, according to scientists. (iStock)
“These well-established aging-related biomarkers have previously been associated with neurocognitive impairment and decline in older non-cancer populations, particularly in cognitive domains related to aging and dementia, such as memory, attention and executive function,” the study stated.
Most of the group consisted of acute lymphoblastic leukemia survivors, or Hodgkin lymphoma survivors. Participants were at least five years past their treatment, though some had survived for several decades.
They underwent neurocognitive testing to measure their attention span, memory and information processing speed.
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Chemotherapy was found to have the greatest impact on aging acceleration. The study suggests the treatment can alter DNA structure and cause cellular damage.
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“It’s no surprise to find out that young people with cancer who have chemo early in life are affected in terms of long-term aging,” Dr. Marc Siegel, senior medical analyst for Fox News, told Fox News Digital.
Participants underwent neurocognitive testing to measure their attention span, memory and speed of information processing. (iStock)
Researchers also found that cellular aging was closely linked to cognitive performance, as survivors of a higher biological age had more difficulty with memory and attention.
“Chemo poisons and damages cellular function — hopefully the cancer cells more than normal cells, but there is a significant impact on normal cells as well,” said Siegel, who was not involved in the study.
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“There is also something called ‘chemo brain,’ which causes at least temporary difficulty with memory, concentration, word finding and brain fog,” the doctor added.
The research team hopes to use these findings to focus on intervention efforts, specifically by determining when accelerated aging begins.
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“Young cancer survivors have many more decades of life to live,” lead study author AnnaLynn Williams, PhD, said in a press release. “If these accelerated aging changes are occurring early on and setting them on a different trajectory, the goal is to intervene to not only increase their lifespan, but improve their quality of life.”
The team hopes this research will help in the development of early intervention tools that aim to prevent cognitive decline. (iStock)
There were some limitations to the study. The researchers could not adjust for chronic health conditions or education because they are directly impacted by treatment.
Additionally, the study only looked at the survivors at a single point of time, so it could not directly prove causation.
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The study was published in the journal Nature Communications.
Fox News Digital reached out to the researchers for comment.
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