Health
Brain health warning sign could be hiding in plain sight, say researchers
NEWYou can now listen to Fox News articles!
A new study from the University of Southern California suggests that the way blood pressure fluctuates from one heartbeat to the next may be just as important as the overall blood pressure reading — especially when it comes to brain health in aging adults.
Researchers found that older adults who experienced greater beat-to-beat changes in blood pressure had smaller brain volumes in areas tied to memory, and higher levels of a protein linked to nerve-cell injury.
“Even when blood pressure is well-controlled with medication, the rapid fluctuation in blood pressure from heartbeat to heartbeat is associated with worse memory and signs of brain shrinkage and brain cell injury,” USC Professor Daniel Nation, senior author of the study, told Fox News Digital.
The study linked rapid blood pressure shifts to smaller memory-related brain regions in older adults. (iStock)
“Blood pressure isn’t static; it’s always adapting to the body’s needs,” he added in a press release. “But as we age, that regulation can become less precise.”
The study included 105 adults between the ages of 55 and 89. The researchers measured the participants’ blood pressure continuously for several minutes while they underwent brain scans.
SCIENTISTS UNCOVER HOW SOME 80-YEAR-OLDS HAVE THE MEMORY OF 50-YEAR-OLDS
In particular, they measured the stiffness of the adults’ arteries and how much their blood pressure changed between heartbeats.
Even when participants’ average blood pressure seemed healthy, those with the most erratic readings — combined with stiffer arteries — showed telltale signs of brain aging, the study found.
People with erratic readings had smaller hippocampal and entorhinal cortex regions, which are among the first areas of the brain affected in Alzheimer’s disease. (iStock)
Specifically, they had smaller hippocampal and entorhinal cortex regions, which are among the first areas of the brain affected in Alzheimer’s disease. They also had higher blood levels of neurofilament light, a biomarker of nerve-cell damage.
These findings were described as significant even after taking into account factors like age, sex and average blood pressure — suggesting that the fluctuations themselves, and not just overall pressure, may be a key risk factor.
The findings were first published online in the Journal of Alzheimer’s Disease on Oct. 17.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
For years, doctors have warned that high blood pressure raises dementia risk, but the USC study explores specifically how moment-to-moment instability can be a cause for concern.
Nation said the researchers were surprised to find that these rapid fluctuations in blood pressure were linked to brain injury, “regardless of whether they have hypertension or are treated with blood pressure-lowering medications.”
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
In other words, someone could have “good” readings at the doctor’s office and still have dangerous spikes and dips that quietly stress the brain’s delicate blood vessels, the research suggests. Over time, that instability could contribute to memory decline and neurodegeneration.
Even well-controlled blood pressure may not protect against brain changes if readings fluctuate too much, the study suggests. (iStock)
The researchers emphasized, however, that this study only shows correlation and does not prove causation, and that more research is needed.
“The findings are correlations in a cross-sectional study, which is like a snapshot in time,” Nation said. “Future studies should examine how these rapid blood pressure fluctuations change over time and whether they predict future brain shrinkage, brain cell injury and memory decline.”
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
The team says there are currently no treatments specifically for these fluctuations.
“But it remains very important that people monitor their blood pressure and take blood pressure-lowering medications as prescribed in order to reduce their risk for brain injury and memory decline,” Nation said.
CLICK HERE FOR MORE HEALTH STORIES
“Development of therapies to address rapid blood pressure fluctuations should be a priority, since these rapid fluctuations are not fully addressed by existing treatments that focus on lowering average blood pressure,” he added.
Health
Dementia risk signals could lie in simple blood pressure readings, researchers say
NEWYou can now listen to Fox News articles!
Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.
That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.
The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.
LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).
Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.
The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”
Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.
HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS
In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.
For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)
The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.
CLICK HERE FOR MORE HEALTH STORIES
“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.
Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)
“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.
Health
Everything You Need To Know About Zepbound for Weight Loss, Including Costs
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
Health
‘Gas station heroin’ banned in another state amid nationwide crackdowns
NEWYou can now listen to Fox News articles!
A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.
Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.
Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.
HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION
Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.
Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.
Tianeptine can be more potent than morphine and addictive opioids. (iStock)
Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.
Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.
The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.
Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)
Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.
“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.
Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”
CLICK HERE FOR MORE LIFESTYLE STORIES
“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”
New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.
“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)
“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”
Schwaner said he believes the substance requires national regulation due to its addictive qualities.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.
Fox News Digital reached out to the FDA for comment.
Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.
-
Detroit, MI1 week agoDrummer Brian Pastoria, longtime Detroit music advocate, dies at 68
-
Science1 week agoHow a Melting Glacier in Antarctica Could Affect Tens of Millions Around the Globe
-
Movie Reviews1 week ago‘Youth’ Twitter review: Ken Karunaas impresses audiences; Suraj Venjaramoodu adds charm; music wins praise | – The Times of India
-
Sports6 days agoIOC addresses execution of 19-year-old Iranian wrestler Saleh Mohammadi
-
New Mexico5 days agoClovis shooting leaves one dead, four injured
-
Business1 week agoDisney’s new CEO says his focus is on storytelling and creativity
-
Technology5 days agoYouTube job scam text: How to spot it fast
-
Tennessee4 days agoTennessee Police Investigating Alleged Assault Involving ‘Reacher’ Star Alan Ritchson