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As Ozzy Osbourne announces stem cell therapy, experts urge caution, highlight risks

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As Ozzy Osbourne announces stem cell therapy, experts urge caution, highlight risks

As rock legend Ozzy Osbourne has turned to stem cell therapy, some experts caution that it’s not for everyone.

At the start of his latest episode of “Ozzy Speaks” on SiriusXM with Billy Morrison, Osbourne revealed that he recently returned from a follow-up appointment “after having some stem cells put in me.”

The rocker also had a previous treatment approximately three months ago, as he stated in the episode.

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“The thing is, you have it, and you go, ‘I don’t feel that great,’ but I don’t know what it would be like if I didn’t have it,” Osbourne said.

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In the past several years, the musician has struggled with several serious medical problems that have impacted his mobility, including Parkinson’s disease, per a report.

Rock legend Ozzy Osbourne has turned to stem cell therapy — but some experts are cautioning that it’s not for everyone. (Getty Images/iStock)

After he first started stem cell treatment in 2020, he wanted “to be a part of the world again,” his daughter Kelly Osbourne said in a report at the time.

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“Seeing, after one treatment of stem cell, what has happened and the progress that he’s made is mind-blowing,” she added.

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Fox News Digital reached out Ozzy Osbourne for comment. 

Below is an overview of the treatment — and what to know about the risks and benefits.

What are stem cells?

Stem cells are found in almost every tissue in the body, according to the Mayo Clinic website.

Some stem cells repair tissues after injury, while others have the potential to become different types of cells, such as brain cells, muscle cells in the heart or bone cells.

“We routinely use cellular therapies, including stem cells, to treat cancers of the blood and bone marrow,” Dr. Mikkael Sekeres, chief of the division of hematology of Sylvester Cancer Center at the University of Miami, told Fox News Digital.

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Some stem cells repair tissues after injury — while others have the potential to become different types of cells, such as brain cells, muscle cells in the heart or bone cells. (iStock)

“The theory is, we can give high doses of chemotherapy to people who have these cancers to eliminate the cancer, but those therapies may have such a high dose that we could wipe out the healthy cells in the bone marrow,” he said.

Alternatively, the doctor went on, experts can “rescue” the bone marrow by giving stem cells to a patient from a healthy donor.

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Another advantage is that the healthy donor stem cells will produce a new immune system to attack and eliminate any remaining cancer, Sekeres added.

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“Use of stem cells in this way has saved tens of thousands of lives,” he noted.

Therapies ‘largely experimental’

Stem cell therapies are only approved by the U.S. Food and Drug Administration (FDA) to treat certain cancers of the blood and immune system, according to the Centers for Disease Control and Prevention (CDC). 

In 2023, the FDA also approved a cord blood-based cell therapy to decrease the risk of infection after stem cell transplants.

Ozzy Osbourne is seen for the first time in this image since announcing he was canceling his tour due to medical concerns. (MEGA for Fox News Digital)

“Stem cell therapy given for other reasons is largely experimental and unproven,” Sekeres noted.

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Despite its potential benefits, stem cell therapy isn’t considered a “silver bullet” for Parkinson’s disease treatment, according to Dr. Michael S. Okun, a Florida-based medical advisor to the Parkinson’s Foundation. 

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“Though there have been many advances in stem cell technology, the realization that Parkinson’s is a disease of more than just dopamine underscores the importance of multidisciplinary treatment,” Okun, who is also the executive director of the Norman Fixel Institute for Neurological Diseases University of Florida Health in Gainesville, Florida, told Fox News Digital.

All stem cell products require the FDA’s approval, according to the agency’s website.

“Folks interested in Parkinson’s stem cell therapy should be cautious if ever offered a treatment,” Okun said.

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Despite its potential benefits, stem cell therapy isn’t considered a “silver bullet” for Parkinson’s disease treatment, a doctor warned.  (iStock)

“We recommend requesting a copy of the institutional review board approval, which is a document verifying that investigators have been authorized to perform research in a human population.”

(An institutional review board ensures ethical treatment of research subjects.)

“Since stem cell therapy is still investigational, you should never be charged to participate in a research trial,” Okun noted.

“Folks interested in Parkinson’s stem cell therapy should be cautious if ever offered a treatment.”

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“There is a large market for ‘stem cell tourism,’ in which people may be charged large sums of money, and in some cases irreversible side effects may follow a transplant.”

Potential adverse side effects

One type of stem cell therapy is a stem cell transplant, which involves infusing another person’s stem cells into the recipient’s body.

Sometimes these stem cells come from the bone marrow, which is known as a bone marrow transplant, according to experts.

In other cases, they are harvested from a baby’s umbilical cord, which is known as a cord blood transplant.

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Some people may experience symptoms of rejection if their immune system recognizes the donor stem cells as “foreign” and starts to attack them.

Acute symptoms may include an itchy rash, diarrhea, general malaise, shortness of breath and yellowing of the eyes, according to the National Health Service.

All stem cell products require the FDA’s approval, according to the agency’s website. (iStock)

Longer-term complications may include infertility, various cancers, cataracts, bone or muscle weakness, and damage to certain organs, such as the liver, kidney, lung or heart, per the National Cancer Institute’s website.

Stem cell therapy should not be viewed as a “fountain of youth,” Sekeres cautioned.

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Previous research published in JAMA Network Open discovered a multi-bacterial outbreak among patients who received unapproved products that were marketed as stem cell therapies, he pointed out.

To verify that a therapy is FDA-approved, the agency recommends emailing ocod@fda.hhs.gov for information, according to its website.

Fox News Digital reached out to the FDA for further comment. 

For more Health articles, visit www.foxnews.com/health

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Change to nightly eating habits may help protect your heart, study suggests

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Change to nightly eating habits may help protect your heart, study suggests

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Abstaining from food three hours before bedtime could benefit heart health, according to a recent study by Northwestern University.

Extending an overnight fast for two hours, dimming the lights and not eating for three hours prior to sleep were shown to improve cardiovascular and metabolic health.

The results were observed among middle-aged and older adults, who are at a higher risk for cardiometabolic disease, as stated in a university press release.

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Time-restricted eating has recently surged in popularity due to its potential to improve heart health and aid in weight loss, the researchers noted.

“But most studies have focused on how long people fast, not how their fast lines up with their sleep schedule — a key factor in metabolic regulation,” the study authors wrote.

Catering time-restricted eating to a sleep cycle could improve heart health, research found. (iStock)

The nearly eight-week study, published in the journal Arteriosclerosis, Thrombosis and Vascular Biology, examined 39 overweight and obese participants between 36 and 75 years old. The intervention group was made up of 80% women.

The participants completed either an extended overnight fasting intervention — 13 to 16 hours — or a “habitual fast” of 11 to 13 hours. Both groups dimmed the lights three hours before bedtime.

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People who finished eating at least three hours before going to bed saw “meaningful improvements” compared to participants who continued with their usual eating routines.

Those improvements included a 3.5% drop in blood pressure and a 5% drop in heart rate, as well as a “more natural drop” in both measures during sleep, which is “an important sign of cardiovascular health,” the researchers found.

People who did not eat three hours before bedtime saw a dip in blood pressure and heart rate. (iStock)

The fasting participants’ hearts also beat faster during the day when they were active and slowed at night during rest — a pattern that’s linked to better heart health.

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Those who abstained from eating also had better daytime blood sugar control, meaning the pancreas responded “more efficiently” when challenged with glucose, “suggesting it could release insulin more effectively and keep blood sugar steadier.”

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First author Dr. Daniela Grimaldi, research associate professor of neurology in the division of sleep medicine at the Northwestern University Feinberg School of Medicine, commented on these findings in a statement.

“Timing our fasting window to work with the body’s natural wake-sleep rhythms can improve the coordination between the heart, metabolism and sleep, all of which work together to protect cardiovascular health,” she said.

Intervention participants experienced lower heart rates during rest. (iStock)

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Grimaldi noted that she and her fellow researchers were “genuinely excited” about the consistent improvements shown.

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“Seeing that a relatively simple change in meal timing could simultaneously improve nighttime autonomic balance, blood pressure dipping, heart rate regulation and morning glucose metabolism, all without calorie restriction or weight loss, was remarkable,” she told Fox News Digital.

Grimaldi noted that the three-hour pre-sleep fasting window is “critical,” because that’s when melatonin rises and the body transitions toward sleep, “a period when eating disrupts metabolism.”

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Sleep expert Dr. Wendy Troxel, RAND Corporation senior behavioral specialist and a licensed clinical psychologist in Utah, emphasized the study’s high adherence rate, at nearly 90%.

“High rates of compliance suggest that this approach may be both feasible and sustainable in real life and could have a demonstrable impact on improving cardiometabolic health,” Troxel, who was not involved in the study, told Fox News Digital.

The three-hour pre-sleep fasting window is “critical,” because that’s the time period when melatonin rises and the body transitions toward sleep, a researcher noted. (iStock)

The findings add to growing research linking sleep and circadian rhythms to cardiovascular health, she added. “In fact, the American Heart Association now recognizes healthy sleep as one of its Life’s Essential 8 pillars for heart health.”

Limitations and future research

Looking ahead, the researchers plan to expand the study to larger, multi-center trials to determine whether the benefits persist or “translate into reduced cardiovascular events or diabetes.” 

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Future studies could also explore the potential benefits of extending time-restricted eating.

“We also want to test this specifically in people with hypertension or diabetes, [who] might benefit most,” Grimaldi shared. “And exploring how this combines with other behavioral interventions, like exercise or morning light exposure, could help us develop more comprehensive strategies for cardiometabolic health.”

The fasting participants’ hearts beat faster during the day when they were active and slowed at night during rest, a pattern that’s linked to better heart health. (iStock)

The high percentage of women poses a study limitation, as it limits the ability to draw “definitive conclusions” about gender differences, Grimaldi acknowledged.

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“We need studies powered to examine sex differences,” she said. “Additionally, our 7.5-week intervention was long enough to show physiological changes, but not long enough to see effects on weight or long-term health outcomes.”

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Northwestern University reported that only 6.8% of adults in the U.S. had optimal cardiometabolic health from 2017 to 2018.

These conditions can lead to chronic illness, including type 2 diabetes, cardiovascular diseases and non-alcoholic fatty liver disease. Heart disease is the No. 1 global killer, according to the CDC. 

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Eating oatmeal for two days has unexpected impact on heart health, study suggests

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Eating oatmeal for two days has unexpected impact on heart health, study suggests

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Eating oats for just a short period of time could have a profound impact on cholesterol levels, according to a recent study.

Researchers from the University of Bonn in Germany conducted a trial in which adults consumed a calorie-reduced diet of almost exclusively oatmeal for two days.

All participants suffered from a metabolic syndrome associated with a risk of diabetes, including a combination of high body weight, high blood pressure, elevated blood glucose or elevated blood lipid levels, according to a university press release.

EVERYDAY SPICE MAY BE KEY TO FIGHTING FAT AND HIGH CHOLESTEROL, SCIENTISTS SAY

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The 32 participants ate oatmeal, previously boiled in water, three times a day, for a total of 300 grams. They were only permitted to add fruits or vegetables to their meals and consumed around half of their normal caloric intake.

A control group was put on a calorie-reduced diet that did not include oats. Although both groups benefited, the cholesterol levels of those on the oat diet “improved significantly.” After six weeks, this effect “remained stable.”

A new study found that eating oats for two days reduced bad cholesterol. (iStock)

Study author Marie-Christine Simon, junior professor at the Institute of Nutritional and Food Science at the University of Bonn, shared in a statement that the level of LDL, or “bad” cholesterol, among the oatmeal-eating group was reduced by 10%.

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“That is a substantial reduction, although not entirely comparable to the effect of modern medications,” Simon said. “They also lost two kilos in weight on average, and their blood pressure fell slightly.”

The authors concluded that the diet influenced microorganisms in the gut, leading to the positive reaction. The results were published in the journal Nature Communications.

Oats significantly reduced cholesterol levels, although not as much as modern medicine. (iStock)

Simon concluded that a short-term oat-based diet at regular intervals “could be a well-tolerated way to keep the cholesterol level within the normal range and prevent diabetes.”

“As a next step, it can now be clarified whether an intensive oat-based diet repeated every six weeks actually has a permanently preventative effect,” she said.

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Certified holistic nutritionist Robin DeCicco, who was not involved in the study, said the findings “make sense” because oats have been known to potentially lower LDL cholesterol.

Oats contain prebiotic fiber that feeds beneficial gut bacteria. When those bacteria ferment the fiber, they produce compounds that support digestive health, according to the expert.

“The more beneficial gut bacteria you have in your stomach, in your environment, the more that can reduce or inhibit the production of LDL bad cholesterol,” New York-based DeCicco told Fox News Digital.

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Oats are also a whole grain that is naturally low in saturated fat and rich in fiber and provides a good amount of plant-based protein.

“All those things are good for a heart-healthy, cholesterol-lowering diet,” DeCicco noted.

Oats are a whole grain that is naturally low in saturated fat and rich in fiber and provides a good amount of plant-based protein, all of which are good for heart health. (iStock)

DeCicco did warn that those who are diabetic or prediabetic should “be careful” when eating oats.

“While oats can lower cholesterol, they are an overly high-carbohydrate food,” she said. “A recommendation for anyone who’s watching their blood sugar, and especially who’s diabetic, is to eat foods that are lower in starch and higher in protein and fiber, [and to get] their carbohydrates more from vegetables and nuts.”

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Megan Wroe, registered dietitian at the Wellness Center at Providence St. Jude Medical Center in Orange County, California, agreed that oat consumption “does seem to lower cholesterol levels for all studied populations, with the greatest impact shown in those with elevated levels.”

“There are no significant risks, but some people may experience cramping or indigestion if they have not previously eaten much fiber and suddenly start eating oats every day,” Wroe, who also was not involved in the study, told Fox News Digital. “Also, those requiring a gluten-free diet will want to ensure that the oats they eat are certified gluten-free.”

The nutritionist also shared the concern that oatmeal is commonly made with water or milk and eaten with added sugar and fruit, which makes it a “potentially very high-glycemic meal.”

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“Knowing this, my recommendation is to eat oats as often as you like, choosing steel-cut or rolled oats, using fruit for sweetness or a low-glycemic sweetener if needed, such as monk fruit,” she advised.

Wroe also suggests finding a way to add protein to balance out the carbohydrates. 

“This can be done by adding chia or flax seeds to the oats, mixing in protein powder or topping with Greek yogurt to serve,” she said.

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Menopause Weight-Loss Breakthrough: Meet 4 Women Over 50 Who Lost 374 Lbs by Building Muscle

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Menopause Weight-Loss Breakthrough: Meet 4 Women Over 50 Who Lost 374 Lbs by Building Muscle


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Meet 4 Women Who Lost 374 Lbs in Menopause by Building Muscle | Woman’s World




















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