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Alaska man dies from novel animal-borne virus, likely contracted from stray cat

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Alaska man dies from novel animal-borne virus, likely contracted from stray cat

The first fatality from Alaskapox, a type of orthopoxvirus, has been reported on the Kenai Peninsula of Alaska.

State officials released a bulletin Feb. 9 detailing that an elderly man contracted the virus in Sept. 2023, likely from an infected stray cat who scratched him.

The man, whose immune system had been suppressed by cancer treatments, first noticed a tender red bump in his underarm. Over the next few weeks, he also experienced fatigue and pain in his arm and shoulder. 

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On Nov. 17, the patient was hospitalized with cellulitis, a bacterial skin infection, according to the Alaska Department of Public Health (ADPH).

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The man was transferred to a hospital in Anchorage, where a series of tests determined the source of his painful infection. Despite extensive treatment, the patient ultimately died in January 2024 after experiencing malnutrition, acute renal failure and respiratory failure, the bulletin said.

An elderly man contracted the virus in Sept. 2023, likely due to the scratch of an infected stray cat (not pictured). (iStock)

“This is the first case of severe Alaskapox infection resulting in hospitalization and death,” the bulletin stated. 

“The patient’s immunocompromised status likely contributed to illness severity.”

What is Alaskapox?

Alaskapox is similar to other orthopox viruses, such as monkeypox and smallpox — but its symptoms are typically not as severe.

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It is a zoonotic virus, which is transmitted between people and animals. 

Alaskapox is spread by small mammals in Alaska, primarily voles.

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Since the first documented case in Fairbanks in 2015, there have only been six additional cases, including the Kenai Peninsula man who succumbed to the infection.

All cases have affected people who lived in wooded areas and had cared for pets who had been in contact with small mammals.

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Lesion on arm

Skin lesions are a primary symptom of Alaskapox, along with swollen lymph nodes and joint or muscle pain, according to the ADPH. (iStock)

Dr. Aaron Glatt, chair of the department of medicine and chief of infectious diseases at Mt. Sinai South Nassau Hospital in New York, pointed out that although Alaskapox is a type of orthopox virus, it’s “nowhere near” as concerning as smallpox.

“It’s in the same family, but that doesn’t mean it [warrants] the same level of worry for the general public,” he said in a phone call with Fox News Digital. 

“I think it’s something we all should be aware of, but it’s not something that presents a major public health disaster.”

It is more similar to monkeypox than smallpox, the doctor said.

“I think it’s something we all should be aware of, but it’s not something that presents a major public health disaster,” Glatt said.

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Spread and symptoms

Although there have been no cases of the virus spreading from person to person, the ADPH recommends that people with skin lesions potentially caused by Alaskapox keep the affected areas covered with a bandage and avoid sharing bedding or other linens.

In addition to the skin lesions, infected patients may experience swollen lymph nodes and joint or muscle pain, according to the ADPH.

Moneypox

Alaskapox is similar to other orthopox viruses, such as monkeypox and smallpox, but its symptoms are typically not as severe. (iStock)

Most patients who have had the virus experienced only mild symptoms that resolved on their own within a few weeks.

“It’s usually a very mild infection, but there’s the potential that it could be more serious in the immunocompromised,” Glatt said. 

“In that case, any mild infection that would normally not cause serious illness can be much more serious.”

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“It’s usually a very mild infection, but there’s the potential that it could be more serious in the immunocompromised.”

“It is likely that the virus is present more broadly in Alaska’s small mammals and that more infections in humans have occurred but were not identified,” the ADPH stated. 

“More animal testing is occurring to better understand the distribution of the virus in animal populations throughout Alaska.”

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To Glatt’s knowledge, there are no targeted medications specifically for Alaskapox.

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“I’m sure that some of the other viral agents that have been used for monkeypox could theoretically have some benefit, but to my knowledge, nobody has tried that,” he said.

As far as whether Alaskapox could spread to other states, Glatt said it’s unlikely at this point.

Kenai Peninsula

The patient who succumbed to Alaskapox lived in a wooded area on the Kenai Peninsula of Alaska. (iStock)

“If it’s an animal vector and the animal is found mostly in Alaska, it’s going to be seen thereabouts,” he told Fox News Digital.

“I can’t tell you that it couldn’t transmit to another area, but at this point in time, it is not a major public health concern.”

The ADPH noted that this was the first case of Alaskapox identified outside the Interior region of Alaska, which could mean the virus is more widespread in the state than previously thought.

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“SOE is working with the University of Alaska Museum and CDC to test small mammals for AKPV outside the Interior region,” the agency stated.

Those who suspect they may be infected with Alaskapox can contact the Alaska Section of Epidemiology at 907-269-8000 to facilitate testing and treatment, per the ADPH.

Fox News Digital reached out to the ADPH for additional comment.

For more Health articles, visit www.foxnews/health.

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Why Does My Cat Follow Me Everywhere? A Pet Pro Explains the Adorable Reasons

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‘COVID paralyzed my diaphragm’: Marathon runner shares how the infection took his breath away

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‘COVID paralyzed my diaphragm’: Marathon runner shares how the infection took his breath away

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Someone with COVID-19 might expect to experience fatigue, cold and flu symptoms, and loss of taste and smell — but a paralyzed diaphragm would likely not be on the radar.

It was certainly a surprise to Gerald Branim, 55, a runner from Tennessee. His life took a drastic turn when COVID-19 damaged his lungs and diaphragm to the extent that he was unable to run or walk for a year.

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Branim and his doctor, Matthew Kaufman of the Institute of Advanced Reconstruction in New Jersey, joined Fox News Digital in an interview to discuss Branim’s ordeal and recovery.

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When Branim got COVID in Feb. 2021, he was a fit, healthy 52-year-old who ran marathons. 

In spite of that, the infection caused significant lung damage. He spent two weeks in the hospital and three months out of work.

Gerald Branim, 55, was a marathon runner when he got COVID, which led to a paralyzed diaphragm that stopped him in his tracks.  (Institute for Advanced Reconstruction)

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For two months after leaving the hospital, Branim used a walker as he continued struggling with lung complications.

“For someone who had run marathons, it was quite humbling to have to walk with a walker for three months,” he said.

After rounds of high-dose steroids and lots of antibiotics, Branim’s chest X-rays finally showed that his lungs had cleared — but he was still having trouble functioning.

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“I still couldn’t go upstairs without my oxygen dropping severely,” he recalled. “I couldn’t run 100 yards without my oxygen dropping into dangerous levels. I was severely out of breath.”

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“That’s when they started saying something else was going on — that this shouldn’t be happening.”

“I couldn’t run 100 yards without my oxygen dropping into dangerous levels. I was severely out of breath.”

After 10 months of not being able to walk or run, Branim’s condition was finally diagnosed via a “sniff test,” which is also called a chest fluoroscopy or a video chest X-ray, where the patient is asked to breathe in and out. 

Any paralysis will show up on the scan, as the diaphragm won’t move upon breathing.

What to know about diaphragm paralysis

Diaphragm paralysis — which is a “pretty rare condition,” according to Kaufman, Branim’s doctor — is paralysis of the diaphragm muscle, which is the primary breathing muscle. 

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Previous studies have estimated that the condition affects only about 1.31% of the population. In about 95% of cases, only one side is paralyzed, the doctor noted.

“We have two diaphragms, one on the right, one on the left,” he said.

Gerald Branim with doctor and patient

Branim, far right, is pictured with his doctor, Matthew Kaufman, center, and another patient at the half-marathon they ran together after Branim’s surgery. (Institute for Advanced Reconstruction)

In cases where both sides are paralyzed, symptoms will be much more severe, usually requiring the patient to be put on oxygen.

“It’s become sort of a phenomenon,” Kaufman told Fox News Digital. “The phrenic nerve, which is the nerve that controls the diaphragm, seems to be an area where the COVID virus can have an impact.”

In some ways, he said, the condition can be considered part of long COVID, which is when symptoms of the virus linger for weeks, months or even years after infection.

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Most people with diaphragm paralysis won’t have difficulty breathing while sitting. Symptoms will typically emerge with exertion, such as walking or exercising, or when changing positions, such as lying flat in bed or bending over to tie their shoes, Kaufman said.

Some people are more susceptible than others, the doctor noted.

“We know that viruses tend to attack nerves in the body, as we’ve seen in Bell’s palsy,” he said. “And now we’re seeing it with COVID causing injury to the phrenic nerve.”

Gerald Branim

Branim set a goal of running a half-marathon within a year of his surgery date, which he achieved alongside his doctor in April 2023. (Institute for Advanced Reconstruction)

Because the condition is rare to begin with, he said, it’s not something that’s universally known.

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“And then you take a condition like COVID, which causes respiratory symptoms from inflammation in the airways and lungs, and then you tie in what we consider to be a neuromuscular problem,” Kaufman said.

“A lot of times, the physician or patient will attribute it to airway inflammation, when in fact it’s a problem related to nerves and muscles that are part of the respiratory system.”

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In some cases, patients will recover on their own, Kaufman said.

“We usually recommend a period of about six to 12 months of physical therapy, breathing exercises and cardiovascular fitness to try to see if this will come back on its own,” he said.

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If improvement is not noticed in that time frame, surgical intervention becomes a possibility.

Gerald Branim

Branim emphasized the importance of patients serving as their own advocates. “Doctors are human — they don’t know everything,” he said. “So you have to advocate for yourself.” (Institute for Advanced Reconstruction)

In 2020 and 2021, Kaufman said he saw an uptick of patients who experienced diaphragm paralysis after having COVID. Although he is still seeing some cases, they are starting to trail off a bit.

“That could be because the classic COVID is not as virulent or severe,” he said. “Or maybe it’s because more people are immunized.”

Although the condition is generally not life-threatening, it can be more severe in patients who have existing respiratory conditions.

Racing toward recovery

After Branim’s diagnosis, his lung doctor advised him to continue to give it time to heal.

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“But it wasn’t getting any better,” he said. “And I just wasn’t satisfied with that being my new quality of life.”

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That’s when Branim turned to Google to research surgical options. He came across an article by Kaufman, a plastic and reconstructive surgeon who specializes in an area called peripheral nerve microsurgery.

Kaufman specializes in conditions that cause either pain or paralysis due to nerve damage of the peripheral nervous system. 

After meeting with Kaufman in a telehealth visit, Branim was identified as a prime candidate for the surgery, which is called phrenic nerve reconstruction. 

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“It wasn’t getting any better — and I just wasn’t satisfied with that being my new quality of life.”

If he had waited much longer, he said, his diaphragm muscle would have atrophied and the surgery would no longer have been possible.

After a lot of back and forth with the insurance company, Branim finally got the green light to travel from Nashville to New Jersey for the procedure.

The surgery went smoothly, although Branim was told that it wouldn’t be an immediate improvement. Once the nerve is fixed, the muscle still needs time to strengthen and rehabilitate.

Gerald Branim

Studies have estimated that the condition affects only about 1.31% of the population. In about 95% of cases, only one side is paralyzed. (Institute for Advanced Reconstruction)

“Dr. Kaufman told me that it would probably take a year or two to recover fully, and was preaching patience — but I’m not a patient man in the slightest sense of the word,” Branim laughed.

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He set a goal of running a half-marathon within a year of his surgery date.

After four weeks, Branim slowly began exercising again. After six months, he decided to lace up his running shoes and give it a try.

“My very first run after the surgery, I ran five miles,” he said. “I literally cried. At that point, it was like a light switch had been flipped.”

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Within six months, Branim had not only regained his ability to run, but exceeded his original goals, culminating in a half-marathon in April 2023.

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In a triumphant twist, Kaufman, who is also a runner, joined his patient in completing the race in Asbury Park, New Jersey.

Now, Branim aims to raise awareness about diaphragm paralysis, an often-overlooked condition that is not on most doctors’ or patients’ radars.

diaphragm

Previous studies have estimated that the condition affects only about 1.31% of the population. In about 95% of cases, only one side is paralyzed. (iStock)

“None of my doctors had even heard of this surgery,” he said. “Had I not found the article about Dr. Kaufman and another runner online, I would have never been able to have the surgery — and I would absolutely not be running today.” 

Branim emphasized the importance of patients serving as their own advocates.

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“Doctors are human — they don’t know everything,” he said. “So you have to advocate for yourself.”

For patients who are experiencing shortness of breath with exertion that persists for several months, Kaufman recommends visiting a primary care physician or pulmonary physician to get the necessary testing.

“While most tests will find more common ailments, it definitely makes sense to keep a paralyzed diaphragm on the list of things to rule out.”

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Why Does My Scalp Smell? Dermatologists Reveal What Women Over 50 Need to Know

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