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AI model Sybil can predict lung cancer risk in patients, study says

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AI model Sybil can predict lung cancer risk in patients, study says

Latest synthetic intelligence (AI) expertise has the flexibility to precisely predict a person’s future lung most cancers danger, based on researchers. 

In a examine printed earlier this 12 months, a crew of worldwide researchers on the Massachusetts Institute of Know-how (MIT), Harvard Medical Faculty and Massachusetts Common Hospital — in addition to in Taiwan — stated the Sybil AI mannequin solely wanted a single low-dose CT (LDCT) scan to “additional allow personalised screening.” 

An LDCT scan is the one really helpful screening check for lung most cancers. Through the scan, sufferers lie on a desk and an X-ray machine makes use of a low quantity of radiation to make detailed photographs of the lungs.

The examine’s authors developed Sybil utilizing scans from the Nationwide Lung Screening Trial, together with these with a variety of smoking historical past. It might probably run in actual time within the background on a radiology studying station. 

AI’S ABILITY TO LEARN POSES CHALLENGE TO REGULATORS, COMPANIES: ‘A LITTLE BIT SCARY’

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Folks stroll by way of the Massachusetts Institute of Know-how campus in Cambridge, Massachusetts, on June 2, 2021. (Adam Glanzman/Bloomberg by way of Getty Photos)

The group discovered that it was proven to precisely predict whether or not an individual will develop lung most cancers within the subsequent 12 months 86% to 94% of the time, and as much as 81% of the time inside six years.

Nonetheless, they famous that future examine is required to know Sybil’s medical functions. 

Lung most cancers is the deadliest most cancers within the U.S., accounting for 23% of all deaths. In 2020, greater than 136,000 folks died of lung most cancers, based on the Facilities for Illness Management and Prevention. The vast majority of these deaths have been in males.

Lung cancer is the deadliest form of cancer in the U.S., accounting for more than 136,000 deaths in 2020.

Lung most cancers is the deadliest type of most cancers within the U.S., accounting for greater than 136,000 deaths in 2020. (iStock)

BE WELL: REDUCE YOUR COLON CANCER RISK WITH REGULAR SCREENINGS

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“It’s the largest most cancers killer as a result of it’s comparatively frequent and comparatively onerous to deal with, particularly as soon as it has reached a complicated stage,” Dr. Florian Fintelmann, Massachusetts Common Most cancers Middle thoracic interventional radiologist and co-author, stated in an announcement. “On this case, it’s essential to know that in case you detect lung most cancers early, the long-term end result is considerably higher. Your five-year survival price is nearer to 70%, whereas in case you detect it when it’s superior, the five-year survival price is simply wanting 10%.” 

Lung most cancers screening applications are underdeveloped in areas of the U.S. hardest hit by lung most cancers attributable to a wide range of components, and Sybil was capable of finding — being skilled each with scans with seen cancerous tumors and a few with out discernible indicators — the place the most cancers was when people could not see it. 

Radiology technologist Mary McPolin looks at a CT scan of a lung with a tumor at the UCSF Comprehensive Cancer Center in San Francisco on Aug. 17, 2005.

Radiology technologist Mary McPolin seems to be at a CT scan of a lung with a tumor at the united states Complete Most cancers Middle in San Francisco on Aug. 17, 2005. (Justin Sullivan/Getty Photos)

The examine was printed within the Journal of Scientific Oncology. 

“We discovered that whereas we [as humans] couldn’t fairly see the place the most cancers was, the mannequin might nonetheless have some predictive energy as to which lung would ultimately develop most cancers,” MIT Ph.D. pupil and co-author Jeremy Wohlwend stated. “Figuring out [Sybil] was capable of spotlight which facet was the almost definitely facet was actually fascinating to us.” 

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Pizza for Weight Loss? Top MD Says This Dough Makes It Possible

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Pizza for Weight Loss? Top MD Says This Dough Makes It Possible



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Feeling hungrier than usual? Your sleep schedule could be the culprit, an expert says

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Feeling hungrier than usual? Your sleep schedule could be the culprit, an expert says

If you’ve been feeling hungrier than usual, it could be due to your sleeping habits.

Human hunger is tied to circadian rhythm, according to experts, which means not sleeping enough can cause a greater appetite.

Dr. Christopher Rhodes, a nutritional biologist in California, explained in a conversation with Fox News Digital that a body deprived of sleep “seeks out energy by way of food.”

AMERICANS NEED MORE SLEEP, LESS STRESS, EXPERTS SAY, AS GALLUP POLL REVEALS TROUBLING FINDINGS

“Sleep and eating are intimately linked due to their shared involvement in both metabolic signaling and your body’s circadian rhythms,” he said. 

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“Just as we train our body on when to expect sleep, we also train it on when to expect food based on our typical mealtimes and dietary patterns throughout the day, which becomes part of our daily circadian cycles.”

Human hunger is tied to circadian rhythm, according to experts, which means not sleeping enough can cause a greater appetite. (iStock)

Poor sleep disrupts hormonal signaling — particularly cortisol, which impacts “metabolic rate and the crucial hormones leptin and ghrelin,” according to Rhodes. 

These hormones are responsible for controlling hunger and the use of energy, he noted.

Extreme disruptions in circadian rhythm — like insomnia or “all-nighters” — can cause a “ripple effect” throughout the body, according to Rhodes.

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“Sleep and eating are intimately linked.”

“[This] can throw our natural rhythms out of whack and cause issues with our biological signaling, changes in hormone levels, chemical signaling and neuronal function,” he said.

“In turn, these imbalances can cause excess hunger and cravings as our body, deprived of the energizing effects of sleep, seeks to compensate by taking in more energy from food,”

woman lies awake in bed

Staying up late at night can throw off the body’s natural rhythm, according to experts. (iStock)

Low-quality sleep can also contribute to poor cognition and reduced brain function, which reduces impulse control, the expert noted.

When these effects are combined with added cravings, and as the body “desperately seek[s] ways to fuel itself,” that can lead to excess food consumption, Rhodes warned.

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Curbing cravings

While it may be difficult to ignore cravings, Rhodes suggested some healthy ways to break the cycle of increased hunger and poor sleep.

It’s best to avoid snacking at bedtime, he said, as energy from snacks can keep you awake.

TYPE 2 DIABETES A MUCH GREATER RISK FOR ‘NIGHT OWLS’ THAN FOR EARLY BIRDS, A ‘STARTLING’ NEW STUDY FINDS

“By and large, the best bedtime snack is none at all,” Rhodes said. “Food intake immediately before bed will cause a rush of nutrients and energy into your system, which can disrupt the natural circadian signaling that helps govern your sleep cycles.”

“Moreover, food before bed can often set off cravings for more food, which can further disrupt your sleep,” he continued. “Small snacks are typically not enough to meet our body’s satiety thresholds and can lead to more hunger throughout the night.”

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Woman eating a doughnut and drinking soda in her kitchen

“It’s best to avoid the canonical ‘midnight munchie’ foods like junk food, cookies, ice cream, pizza and especially alcohol,” the expert said. (iStock)

It’s best to eat at least four to six hours before falling asleep, according to Rhodes, to allow the body to fully metabolize food and store excess energy that could disrupt sleep.

“Focus on foods that have a low glycemic impact and are slow digesting — like lean proteins, healthy nuts or fibrous veggies — to avoid blood sugar spikes,” he said.

LACK OF SLEEP COULD BE A FACTOR IN A ‘SILENT EPIDEMIC,’ EXPERTS WARN

It’s also best to avoid the traditional “midnight munchie” foods like junk food, cookies, ice cream and pizza, he advised — “especially alcohol, as it has been shown to have particularly adverse effects on sleep quality.”

Despite the preconceived idea that breakfast is the most important meal of the day, Rhodes suggested following your body’s natural hunger cues. 

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“Breakfast is just another meal like any other, and not the end all be all of your daily well-being,” he said.

woman sits in front of an empty plate.

“If you don’t feel hungry in the morning, it’s best to just follow your body’s natural cues than to force yourself to eat a meal out of obligation,” Rhodes advised. (iStock)

“If you don’t feel hungry in the morning, it’s best to just follow your body’s natural cues than to force yourself to eat a meal out of obligation.”

There may be health benefits for some people who cut breakfast out of their diet, Rhodes mentioned, as studies have shown that intermittent fasting can have positive effects on blood glucose control, cognition and cholesterol levels.

WANT TO BE A MORNING PERSON? THESE 6 EXPERT TIPS MAY GET YOU THERE

One easy way to boost energy and satiety throughout the day is to drink hot green tea or other balanced energy drinks that contain caffeine and L-theanine, to “provide sustained energy without jitters or a crash,” Rhodes said.

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You sleep how you eat

The food you choose to eat can determine the quality of your sleep, according to experts.

“Quality of sleep can be altered by a number of nutritional factors, including blood glucose spikes, total caloric intake, vitamin and nutrient deficiencies, supplements, meal timing and more,” Rhodes said. 

“Insomnia and poor sleep quality have been linked with a higher risk of obesity in many studies.” 

Eat sleep split

The food you eat can determine the quality of your sleep, according to experts. (iStock)

It’s also important to avoid deficiencies in vitamins A, C, D, E, K, calcium and magnesium, which can affect sleep quality.

“Of these, magnesium supplementation may be the most beneficial, as it’s estimated that 75% of Americans are currently deficient, and magnesium supplementation is well-known to promote calm and support sleep quality,” Rhodes added.

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“Insomnia and poor sleep quality have been linked with a higher risk of obesity.”

The most important aspect of maintaining good sleep and eating habits, regardless of lifestyle, is staying as consistent as possible in your day-to-day schedule, according to Rhodes.

“Stabilizing your circadian rhythms will help to improve cognition, mood, hunger signaling and sleep quality by avoiding the hormonal, chemical and neuronal disruptions that can be caused by inconsistent circadian signaling,” Rhodes said.

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“Eating the same meals in the same amounts at the same time every day and maintaining a consistent sleeping schedule will help retrain your body’s circadian rhythms and signaling, so that your atypical work and eating hours will become normal to your body.”

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The expert suggested large batch meal prepping as a way to cut down on time spent cooking while also ensuring a “healthy, consistent meal” on hand when needed.

Woman preparing a nutritious meal in advance

Meal prepping is a great way to save time and ensure nutritious food intake, Rhodes said. (iStock)

For even better sleep, Rhodes recommended buying tools such as earplugs, night masks or blackout curtains to avoid distractions.

“If needed, a melatonin supplement can help you fall asleep faster and stay asleep longer, and helps to accelerate adaptations to new sleeping schedules by normalizing sleep hormone production and circadian signaling,” he added.

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Melanoma patients reveal dramatic stories for Skin Cancer Awareness Month: ‘I thought I was careful’

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Melanoma patients reveal dramatic stories for Skin Cancer Awareness Month: ‘I thought I was careful’

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Skin cancer is the most common type of cancer in the U.S. — with one in five Americans developing the disease by the age of 70.

Melanoma is the deadliest form of skin cancer, expected to take the lives of more than 8,200 people in the U.S. this year.

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This May, for Skin Cancer Awareness Month, two melanoma patients are sharing their stories of how they overcame this invasive form of the disease.

SKIN CANCER CHECKS AND SUNSCREEN: WHY THESE (STILL) MATTER VERY MUCH FOR GOOD HEALTH

One even wrongly assumed that what she was experiencing “was just a normal part of aging and sun exposure.” Here’s what others can learn.

What is melanoma?

Melanoma is a type of skin cancer that starts in the melanocytes, which are the cells that produce the skin’s pigmentation (color).

Most cases — but not all — are caused by exposure to ultraviolet light. Melanoma can affect people of all skin tones and types.

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“Melanoma is one of the most common type of cancer in younger patients,” Nayoung Lee, M.D., assistant professor of dermatology at NYU Langone Health, told Fox News Digital.

Abby Weiner, pictured at left and at right with her husband and sons, was diagnosed with melanoma in Oct. 2023.  (Abby Weiner)

The prognosis is “very good” when melanoma is detected early, but the survival rate falls steeply when it is detected at a more advanced stage, she noted. 

“Melanoma can spread through the bloodstream to your lymph nodes and distant organs, so it is crucial to do regular skin exams to try to catch it at an early stage,” Lee said.

One mom’s story

Abby Weiner, 43, a wife and mother of three young boys living in Washington, D.C., had always been careful about protecting her skin from the sun — which is why her Oct. 2023 melanoma diagnosis was such a shock, she said.

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“I had a spot on my cheek that started as a freckle and began getting darker and larger,” she told Fox News Digital. 

“I assumed it was just a normal part of aging and sun exposure.”

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Weiner’s sister encouraged her to get it checked out — which led to a biopsy and diagnosis. 

“I was obviously shocked and frightened at first,” said Weiner.  

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Her melanoma was removed using Mohs surgery, a procedure in which thin layers of skin are removed one at a time. 

“I required two procedures to remove the cancer and surrounding margins,” she said. “Now, most people don’t even know I had surgery.”

To others, Weiner’s advice is to remember to seek shade, wear sun-protective clothing, and apply a broad-spectrum, water-resistant sunscreen with an SPF of 30 or higher on a daily basis all year long. 

“If we were eating outdoors and there wasn’t a table in the shade, I would end up sitting in the sun.”

“I thought I was careful about protecting myself from sun exposure by wearing a hat or applying sunscreen when my family was at the pool or planning to be outdoors — but if we were eating outdoors and there wasn’t a table in the shade, I would end up sitting in the sun.”

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Now, Weiner said she will wait a little longer for a shaded table, and she always keeps a hat and sunscreen with her.

“My sons used to have difficulty applying sunscreen and wearing hats, but now that they’ve seen the impact skin cancer had on me, they are more cooperative,” she said.

CANCER SCREENINGS: HERE ARE 5 TYPES AND CRITICAL INFORMATION TO KNOW ABOUT EACH

Weiner also recommends that everyone gets yearly skin checks with a board-certified dermatologist

“I have so many friends — and even my sister, who probably saved my life — who didn’t regularly see a dermatologist for a yearly skin check before they learned about my melanoma.”

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One beach lover’s story

Steve Murray, 68, of the greater Washington, D.C. area, has worked in construction for several decades. 

During his childhood, Murray spent summers at the beach in Ocean City, New Jersey, and winter visits to Florida, where he was exposed to the sun and didn’t do much to protect himself.

In the late 1990s, Murray was diagnosed with basal cell carcinoma, the most common type of skin cancer, and squamous cell carcinoma, a variation of skin cancer that tends to develop in people who have had a lot of sun exposure.

In 2008, he was diagnosed with melanoma.

“My initial symptoms included itching and scaling on my head, followed by irritation,” he told Fox News Digital. 

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“Then there was discoloration and irregularity in the shape of my moles.”

“You don’t notice at the time of initial exposure, but it haunts you later in life.”

Initially, Murray feared the worst — “mainly death” — but his dermatologist determined that the melanoma was only on his scalp and hadn’t traveled to his lymph nodes.

Like Weiner, Murray had Mohs surgery to get rid of the cancer — and he was cleared.

VIRGINIA HIGH SCHOOL STUDENT CREATES SOAP TO FIGHT SKIN CANCER, IS AWARDED $25K: ‘REMARKABLE EFFORT’

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Since that diagnosis, Murray has had several more bouts of skin cancer.

In 2024, he underwent two surgeries for squamous cell carcinoma on his hand and back. 

Now, Murray visits the dermatologist every three to six months. Also, he always wears a hat, sunscreen and long sleeves whenever possible to protect himself from the sun.

Abby Weiner

Abby Weiner is pictured with her three young sons. “My sons used to have difficulty applying sunscreen and wearing hats, but now that they’ve seen the impact skin cancer had on me, they are more cooperative,” she said. (Abby Weiner)

Murray’s advice to others is to make sun protection a priority when outdoors.

“You don’t notice at the time of initial exposure, but it haunts you later in life when you start developing pre-cancers and skin cancers like squamous cell carcinoma and melanoma that require immediate attention,” he told Fox News Digital.

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“Capturing these pre-cancers and cancers of the skin must be diagnosed early with regular checkups,” he added. “Failure to do so could lead to death.”

5 protection tips from an expert

Dr. Lee of NYU Langone Health shared five tips to help prevent potentially deadly skin cancers like melanoma.

1. Skip the sunbathing

“Avoiding a burn is really only half the battle — there is no such thing as a base tan,” Lee said. “Damaged skin is damaged skin.”

For a safer way to achieve a sun-kissed glow on your first beach day of the summer, Lee recommends using self-tanning products.

2. Wear sunscreen every day, in all weather and in every season

When applying sunscreen, Lee recommends using 1 ounce, which would fill a shot glass. 

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IF YOU OR YOUR CHILDREN HAVE FRECKLES, HERE’S WHAT YOUR SKIN IS TRYING TO TELL YOU

“It should have a sun protection factor (SPF) of 30 and say ‘broad-spectrum’ on the label, which protects against the sun’s UVA and UVB rays,” she said. 

Reapply at least every 80 minutes, or more often if you’re sweating or swimming.

3. Use physical sunscreen

Physical sunscreen contains zinc or titanium, which is superior in efficacy to chemical sunscreen, according to Lee.

4. Learn how to do a skin self-exam

“Check your skin regularly so you know what’s normal and to notice any changes or new growths,” Lee advised. 

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Skin check

“Not all melanomas are dark and scary-appearing,” a doctor said. “They can be amelanotic, which means they can be more skin colored or pink.” (iStock)

“Seek a dermatologist’s evaluation if you notice a changing, bleeding or persistently itchy spot.”

5. Apply the ABCDE rule

This is the best way to determine if any mole or blemish is cancerous, according to Lee. 

The ABCDE rule tells you what to look for when examining your skin

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The A stands for asymmetrical. “Noncancerous moles are typically symmetrical,” Lee said. 

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B is for border, as the border of a cancerous spot or mole may be irregular or blurred. 

The ABCDE rule is the best way to determine if any mole or blemish is cancerous, according to a dermatologist. (iStock)

C stands for color. “A typical mole tends to be evenly colored, usually a single shade of brown,” Lee noted. 

“Not all melanomas are dark and scary-appearing. They can be amelanotic, which means they can be more skin colored or pink.”

D stands for diameter of the spot or mole, which may be a warning sign if it’s larger than 6 millimeters, according to Lee.

If the spot is evolving, which is what E stands for, it might be of concern.

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Lee added, “Because melanomas can vary in appearance, it is important to see a dermatologist regularly for skin exams if you have a history of significant sun exposure, have many atypical appearing moles, or a family or personal history of melanoma so that you have an experienced set of eyes looking at any spots of concern.”

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