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51 inspirational quotes to help you stay strong, healthy and motivated in tough times

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51 inspirational quotes to help you stay strong, healthy and motivated in tough times

There’s a reason quotes and inspirational sayings from people of all walks of life (and many periods of history) have staying power.

Words of wisdom and reflection can offer solace, comfort and inspiration when times are hard.

They can do this at any time, really.  

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Here, in no particular order, are 51 memorable quotes that offer strong reminders of the importance of self-care and of the power of positive thinking — and more.

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51 memorable quotes for staying strong, healthy and motivated

1. “Love yourself first and everything else falls in line. You really have to love yourself to get anything done in this world.” — Lucille Ball

“Love yourself first and everything else falls in line. You really have to love yourself to get anything done in this world.” — Lucille Ball (CBS via Getty Images)

2. “When you let fear make your decisions, you relinquish your belief in yourself or in another person.” — Admiral Bob Harward

3. “Never bend your head. Always hold it high. Look the world straight in the face.” — Helen Keller

4. “We must be our own before we can be another’s.” — Ralph Waldo Emerson

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5. “Keep good company, read good books, love good things, and cultivate soul and body as faithfully as you can.” — Louisa May Alcott

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6. “I remain an incorrigible optimist. America has overcome daunting odds time and again … I would never bet against the American people.” — Neil Gorsuch

7. “The most important investment you can make is in yourself. Very few people get anything like their potential horsepower translated into the actual horsepower of their output in life. Potential exceeds realization for many people … The best asset is your own self. You can become to an enormous degree the person you want to be.” — Warren Buffett

8. “We have to be intentional with the life that we have.” — Amy Grant

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“We have to be intentional with the life that we have.” — Amy Grant (Allison Dinner/Getty Images)

9. “Our bodies are our gardens, to which our wills are gardeners.” — William Shakepeare 

10. “Every small positive change we make in ourselves repays us in confidence in the future.” — Alice Walker

11. “I might tell a story, but usually I try to remind people that they should be happy.” — Don McLean

12. “If you’re facing a problem, don’t tell yourself that you can’t do it. Convince yourself that you have the strength to deal with almost anything … And you do! Recognizing your core strengths is an important step toward having joie de vivre. You can count on better days to come because of the good days that came before. And you can find joy in the moment because you have the resiliency to overcome the problems that may be hanging over you.” — Ruth K. Westheimer

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13. “The most important thing in life is to stop saying ‘I wish’ and start saying ‘I will.’ Consider nothing impossible, then treat possibilities as probabilities.” — Charles Dickens

14. “Faith is the very first thing you should pack in a hope chest.” — Sarah Ban Breathnach

15. “You never know how strong you are until being strong is your only choice.” — Bob Marley

16. “Only I can change my life. No one can do it for me.” — Carol Burnett

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“Only I can change my life. No one can do it for me.” — Carol Burnett (Getty Images)

17. “The secret to a happy life is to accept change gracefully.” — Jimmy Stewart

18. “Gratitude unlocks the fullness of life. It turns what we have into enough, and more. It turns denial into acceptance, chaos to order, confusion to clarity.” — Melody Beattie

19. “You can’t go back and change the beginning, but you can start where you are and change the ending.” — C.S. Lewis

20. “A smile is a curve that sets everything straight.” — Phyllis Diller

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21. “Be patient with yourself. Self-growth is tender; it’s holy ground. There’s no greater investment.” — Stephen Covey

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22. “I really built myself up, darn it, to be very strong.” — Barbara Bush

23. “My philosophy of life is that if we make up our mind what we are going to make of our lives, then work hard toward that goal, we never lose — somehow we win out.” — Ronald Reagan

24. “Reinforce yourself by remembering that you have been resilient and have persevered to overcome challenging and troublesome situations in the past.” — Jennifer Guttman

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25. “I challenge you to make your life a masterpiece. I challenge you to join the ranks of those people who live what they teach, who walk their talk.” — Tony Robbins

“I challenge you to make your life a masterpiece. I challenge you to join the ranks of those people who live what they teach, who walk their talk.” — Tony Robbins (FOX)

26. “When I am constantly running there is no time for being. When there is no time for being there is no time for listening.” — Madeleine L’Engle

27. “If you’re peaceful at home, then you extend that to your family, extend that to your community. And I hope that if we extend that to a critical mass, we can have a more peaceful, just, sustainable, healthier and joyful world. That’s the ultimate dream.” — Deepak Chopra

28. “If you want to live an authentic, meaningful life, you need to master the art of disappointing and upsetting others, hurting feelings, and living with the reality that some people just won’t like you. It may not be easy, but it’s essential if you want your life to reflect your deepest desires, values, and needs.” — Cheryl Richardson

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29. “Make the mental commitment that, God willing, nothing will stop you from ‘going the distance.’” — Alex McFarland

30. “If you aren’t good at loving yourself, you will have a difficult time loving anyone, since you’ll resent the time and energy you give another person that you aren’t even giving to yourself.” Barbara De Angelis

31. “Strength does not come from winning. Your struggles develop your strengths. When you go through hardships and decide not to surrender, that is strength.” — Arnold Schwarzenegger

32. “A balanced life doesn’t come from being a know-it-all about every nuance of Ashtanga yoga. It comes instead from knowing what you need so that you can keep learning and evolving for months and years to come.” — Mariel Hemingway

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“A balanced life doesn’t come from being a know-it-all about every nuance of Ashtanga yoga. It comes instead from knowing what you need so that you can keep learning and evolving for months and years to come.” — Mariel Hemingway (Getty Images)

33. “I’m just thankful for everything, all the blessings in my life, trying to stay that way. I think that’s the best way to start your day and finish your day. It keeps everything in perspective.” — Tim Tebow

34. “You gain strength, courage, and confidence by every experience in which you really stop to look fear in the face.” — Eleanor Roosevelt

35. “Promise me you’ll always remember: You’re braver than you believe, and stronger than you seem, and smarter than you think.” — A. A. Milne

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36. “Life is not easy for any of us. But what of that? We must have perseverance and above all confidence in ourselves.” — Marie Curie

37. “Life shrinks or expands according to one’s courage.” — Anaïs Nin

38. “Self-care should include the cold shower as well as the scented tub.” — Mary Catherine Bateson

39. “Relax. Look around. Make a call.” — Jocko Willink

“Relax. Look around. Make a call.” — Jocko Willink (Jason Kempin/Getty Images)

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40. “One cannot think well, love well, sleep well, if one has not dined well.” — Virginia Woolf

41. “Strength does not come from physical capacity. It comes from an indomitable will.” — Mahatma Gandhi

42. “Above all, be the heroine of your life, not the victim.” — Nora Ephron

43. “Just as self-respect and pride bring out the best in an individual, pride in family, pride in teammates, pride in hometown bring out the best in groups of people.” — Andy Rooney

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44. “The only bad workout is the one that didn’t happen.” — Unknown

45. “Spread love everywhere you go. Let no one ever come without leaving happier.” — Mother Teresa

46. “If you want to live a happy life, tie it to a goal, not to people or things.” — Albert Einstein

“If you want to live a happy life, tie it to a goal, not to people or things.” — Albert Einstein (iStock)

47. “Never let the fear of striking out keep you from playing the game.” — Babe Ruth

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48. “We turn not older with years but newer every day.” — Emily Dickinson

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49. “Most of the important things in the world have been accomplished by people who have kept on trying when there seemed to be no hope at all.” — Dale Carnegie

50. “It takes courage to live in this world. It takes courage to speak truth, and it takes even more courage to live according to the highest ideals of your heart.” — Joan Gattuso

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51. “A good laugh and a long sleep are the best cures in the doctor’s book.” — Irish proverb

Health

Do collagen supplements really improve skin? Major review reveals the truth

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Do collagen supplements really improve skin? Major review reveals the truth

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Collagen supplements have exploded in popularity, touted as everything from an anti-aging miracle to a muscle recovery booster.

But a sweeping new review conducted by U.K. researchers suggests that while collagen may help improve skin elasticity and ease arthritis pain, it does little for athletic performance or wrinkle reduction.

Researchers from Anglia Ruskin University analyzed 16 systematic reviews and 113 randomized controlled trials involving nearly 8,000 participants worldwide, which they say is the most extensive evaluation of collagen’s health effects to date. 

The review found consistent evidence that collagen supplementation improves skin elasticity and hydration over time and provides significant relief from osteoarthritis-related joint pain and stiffness, according to findings published in Aesthetic Surgery Journal Open Forum. 

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A large U.K. review found that collagen supplements may improve skin elasticity and hydration over time. (iStock)

The researchers, however, did not find meaningful improvements in post-exercise muscle recovery, soreness or tendon mechanical properties (strength, springiness and stretch resistance).

“Collagen is not a cure-all, but it does have credible benefits when used consistently over time, particularly for skin and osteoarthritis,” co-author Lee Smith, professor of public health at Anglia Ruskin University, said in a statement.

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“Our findings show clear benefits in key areas of healthy aging, while also dispelling some of the myths surrounding its use,” Smith added.

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Collagen, the most abundant protein in the body, supports skin, bones, tendons, cartilage and connective tissue, according to experts. Natural collagen production begins to drop in early adulthood and declines more sharply with age.

The study found that collagen supplements may help reduce joint pain and stiffness in people with osteoarthritis. (iStock)

The review found that long-term collagen supplementation was linked to improved skin firmness and hydration, but did not help skin roughness — a proxy for visible wrinkles. 

Benefits appear to accumulate gradually, suggesting that collagen should not be viewed as an “anti-wrinkle ‘quick fix,’ but as a foundational dermal support for individuals seeking holistic skin maintenance,” the researchers said.

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“If we define anti-aging as a product or technique designed to prevent the appearance of getting older, then I believe our findings do support this claim for some parameters,” Smith told the BBC. “For example, an improvement in skin tone and moisture is associated with a more youthful-looking appearance.”

Collagen supplementation was linked to reduced pain and stiffness in people with osteoarthritis, with stronger benefits seen over longer periods of use, and showed modest improvements in muscle mass and tendon structure that may support healthy aging. 

Collagen did not significantly improve skin roughness, a marker of visible wrinkles. (iStock)

However, it did not show meaningful results when used as a fast-acting sports performance supplement, and evidence for benefits related to cholesterol, blood sugar, blood pressure and oral health was mixed or inconclusive.

Dr. Daniel Ghiyam, a California-based physician and longevity specialist, said the findings align with what he sees in clinical practice.

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“Collagen is a targeted support tool, not a foundation of health or performance,” Ghiyam, who was not involved in the study, told Fox News Digital. “When marketed that way, it makes sense. When marketed as a cure-all, it doesn’t hold up to the data.”

The authors noted that while many previous collagen studies have received financial support from the supplement industry, the current review did not receive industry funding.

Experts say collagen supplements may offer modest benefits for skin hydration and joint comfort, but they are not a cure-all. (iStock)

The team called for more high-quality clinical trials examining long-term outcomes, optimal dosages and differences between collagen sources, such as marine, bovine and plant-based alternatives. 

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Among its limitations, the review could not determine whether certain forms of collagen work better than others or what the optimal regimen should be. 

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While the review included randomized controlled trials, the quality of the studies varied, with newer research generally showing stronger results.

Experts say more data and studies are needed to build on the findings. They also noted that diet plays a crucial role in skin health.

Collagen supplements, often sold as powders or pills, may improve skin elasticity and ease joint pain, experts say. (iStock)

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Dr. Erum Ilyas, a Pennsylvania-based dermatologist and chair of dermatology at Drexel University College of Medicine, noted that the review analyzed previously published meta-analyses rather than generating new primary data.

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“At this time, I have not seen sufficiently strong independent evidence to routinely recommend collagen supplements to my patients,” Ilyas, who was not involved in the review, told Fox News Digital.

“Although some studies show modest improvements in markers such as hydration and elasticity, there remains limited independent, biopsy-confirmed evidence demonstrating sustained increases in dermal collagen content,” she added.

Fox News Digital has reached out to the researchers for comment.

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Origin of deadly cancer affecting young adults revealed in alarming report

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Origin of deadly cancer affecting young adults revealed in alarming report

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As colorectal cancer (CRC) is now the leading cause of cancer death in adults under 50, a new report reveals some surprising shifts in the incidence of the disease.

Although rates of CRC have been declining among seniors, those 65 and under are facing a rise in diagnoses, according to a report titled Colorectal Cancer Statistics, 2026, from the American Cancer Society.

Adults 65 and younger comprise nearly half (45%) of all new colorectal cancer cases — a significant increase from 27% in 1995, states the report, which was published in CA: A Cancer Journal for Clinicians.

The disease is rising fastest among adults 20 to 49 years old, at a rate of 3% per year.

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Colorectal cancer is now the leading cause of cancer death in adults under 50. (iStock)

Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. Although that age group is eligible to receive routine screenings, just 37% do so.

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The report also revealed that rectal cancer is on the rise, now accounting for about one-third (32%) of all CRC cases — an increase from 27% in the mid-2000s.

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“After decades of progress, the risk of dying from colorectal cancer is climbing in younger generations of men and women, confirming a real uptick in disease because of something we’re doing or some other exposure,” said Rebecca Siegel, senior scientific director, surveillance research at the American Cancer Society and lead author of the report, in a press release.

Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49.  (iStock)

“We need to redouble research efforts to understand the cause, but also circumvent deaths through earlier detection by educating clinicians and the general public about symptoms and increasing screening in people 45-54 years.”

It is projected that 158,850 new cases of colorectal cancer will be diagnosed this year, and that the disease will cause 55,230 deaths, per the report.

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More than half of CRC cases can be linked to high-risk behaviors, the researchers said. Those include lack of nutrition, high alcohol consumption, smoking, lack of exercise and obesity.

“These findings further underscore that colorectal cancer is worsening among younger generations and highlight the immediate need for eligible adults to begin screening at the recommended age of 45,” said Dr. William Dahut, chief scientific officer at the American Cancer Society.

When the disease is caught at a local (early) stage, the five-year survival rate is 95%. (iStock)

“The report also shines a light on the crucial importance of continued funding for research to help discover new therapies to treat the disease and advance patient care.”

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When the disease is caught at a local (early) stage, the five-year survival rate is 95%, the report stated.

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Aging process could accelerate due to ‘forever chemicals’ exposure, study finds

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Aging process could accelerate due to ‘forever chemicals’ exposure, study finds

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A new study suggests that middle-aged men may be more vulnerable to faster biological aging, potentially linked to exposure to “forever chemicals.”

The research, published in the journal Frontiers in Aging, examined how perfluoroalkyl and polyfluoroalkyl substances, more commonly known as PFAS, could impact aging at the cellular level.

PFAS are synthetic chemicals commonly used in nonstick cookware, food packaging, water-resistant fabrics and other consumer products, the study noted. 

Their chemical structure makes them highly resistant to breaking down, allowing them to accumulate in water, soil and the human body.

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Chinese researchers analyzed blood samples from 326 adults enrolled in the U.S. National Health and Nutrition Examination Survey between 1999 and 2000.

A new study suggests that middle-aged men could face accelerated biological aging at the cellular level due to exposure to PFAS. (iStock)

The researchers measured levels of 11 PFAS compounds in participants’ blood and used DNA-based “epigenetic clocks” — tools that analyze chemical changes to DNA to estimate biological age — to determine how quickly their bodies were aging at the cellular level, the study stated.

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Two compounds, perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA), were detected in 95% of participants.

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Higher concentrations of those chemicals were associated with faster biological aging in men of certain age groups, but not in women.

“People should not panic.”

The compounds most strongly linked to accelerated aging were not the PFAS chemicals that typically receive the most public attention, the researchers noted.

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“The associations were strongest in adults aged 50 to 64, particularly in men,” Dr. Xiangwei Li, professor at Shanghai Jiao Tong University School of Medicine and the study’s corresponding author, told Fox News Digital. 

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“While this does not establish that PFAS cause aging, it suggests that these widely present ‘forever chemicals’ may be linked to molecular changes related to long-term health and aging.”

The study found that two of the compounds were detected in 95% of participants, and higher levels were linked to faster biological aging in men ages 50–64. (iStock)

Midlife may represent a more sensitive biological period, when the body becomes more vulnerable to age-related stressors, according to the researchers.

Lifestyle factors, such as smoking, may influence biological aging markers, potentially increasing vulnerability to environmental pollutants.

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While Li said “people should not panic,” she does recommend looking for reasonable ways to reduce exposure. 

That might mean checking local drinking water reports, using certified water filters designed to reduce PFAS, and limiting the use of stain- or grease-resistant products when alternatives are available.

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Meaningful reductions in PFAS exposure will likely depend on broader regulatory action and environmental cleanup efforts, Li added.

The researchers noted that midlife could be a particularly sensitive stage, when the body is more susceptible to stressors associated with aging. (iStock)

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Study limitations

The researchers outlined several important limitations of the research, including that the findings show an association, but do not prove that PFAS directly causes accelerated aging.

“The study is cross-sectional, meaning exposure and aging markers were measured at the same time, so we cannot determine causality,” Li told Fox News Digital.

The study was also relatively small, limited to 326 adults age 50 or older, which means the findings may not apply to younger people or broader populations.

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Researchers measured PFAS levels using data collected between 1999 and 2000, and today’s exposure patterns may differ.

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Li added that while PFAS is known to persist in the environment and the body, these results should be validated through larger, more recent studies that follow participants over time.

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