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A long-term fitness study at Queen’s University that is exploring the effects of exercise is once again in recruiting mode.

A long-term fitness study at Queen’s University that is exploring the effects of exercise is once again in recruiting mode.
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“The basis of this is one size doesn’t fit all and what size fits you as an individual,” said Bernadette Garrah, project co-ordinator of the Revise Research Study with the Lifestyle and Cardiometaboic research unit at Queen’s.
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“We’re really trying to link that to exercise as well, to be the most inclusive and to be the most supportive of finding essentially what works for all individuals for exercise,” Garrah added.
The 32-week exercise study, which is examining the effects of different levels of exercise on fitness and body composition, started in September 2022 and is currently seeking members of the community between the ages of 25 and 65, who are currently not physically active. Those selected will be subject to a series of assessments at no cost, and based on the results will receive an individualized exercise prescription, where participants will come for supervised exercise at the facility.
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“Following the Canadian guidelines (of a recommended) 115 minutes of exercise a week, about 30 minutes a day, a brisk walk, that’s what our participants will do here,” Garrah said. “Thirty minutes of walking a day is kind of where this started.”
The process, Garrah said, starts with a recruitment meeting, where participants will hear from Dr. Robert Ross, who is heading the study.
“They’ll listen to Dr. Ross, the (principle investigator) on this study, basically talk about what’s going on and if they decide to sign up, then we get them enrolled right away. It starts with assessments. Once they’ve done the baseline assessments, we’ll randomize them and they’re either going to be put into the control group or the exercise group,” Garrah explained.
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“From the time that you start until the time that you’re done, it’s about eight months, 32 weeks-ish, give or take,” Garrah said. “Once you start, if you are part of the control group, it’s just as good as the exercise group, the only thing is you don’t start exercising right away. It’s essentially a placebo. That’s what it is in research. We need to have this group; it’s very important. Members of that group will do all the same assessments that exercisers do, they’re simply waiting until the 16-week mark comes around to start their exercise.”
Susan Foley, who recently finished her eight months as part of the low-amount, low-intensity exercise group, praised the study and the folks behind it.
“I learned about it from Facebook,” Foley said. “I was 63, I had had a heart attack in the past and my risk factors were sedentary lifestyle. So when I saw this study and it talked about exercising, it seemed to be everything that I needed to get exercise in my life.”
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Foley, who said she had participated in a program for heart attack survivors in the past but found that it was short term with participants asked to continue to exercise at home, which didn’t work for her. That, she said, and the one-size-fits-all regimen proved to be too onerous for her and too demanding on her knees and joints.
The Queen’s study, Foley said, came along at a time when she found herself soul-searching following the loss of her son.
“I started in around September,” she said. “I had lost my son in the summer and I thought, ‘I need to be doing something for myself and get exercise in my life, get healthier.’ My heart attack was in 2017 and I still hadn’t gotten into regular exercise. That’s what brought me in here.”
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Foley, feeling better than she says she has in a long time, almost wasn’t a participant in the program, she said. Before coming to orientation, she’d accepted a new job after having been previously retired. The day she attended orientation, she’d all but convinced herself she didn’t have the time to participate in an eight-month study, she said.
“I was thinking, ‘I can’t do this, I can’t commit to this, it’s going to take up too much time,’ even though I wanted to,” Foley said. “But when I heard Dr. Ross, the things that I was worried about and the things that I wanted for my health were all addressed. It is very individualized. They took into consideration my health past, my heart attack, also at my age. I was worried about bone density. I also was already having trouble at my age with balance, ankles and trouble going up and down stairs, pain in my knees. Plus, having had the heart attack, I have never yet been able to do a consistent exercise program. This study kind of was offering everything that I felt I needed to change.”
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Garrah said that while 32 weeks can seem like a huge commitment, the ask isn’t as overwhelming as the time frame might suggest.
“People say, ‘Oh, I have to do this for 32 weeks,’ but it’s 30 minutes of walking a day,” she said. “And we hope that you can do this for the rest of your life. If you do do this study, you’re doing this for eight months. Susan comes from Sydenham, parks, walks up to the fifth floor, is here for half an hour to an hour, depending on her exercise prescription, for eight months.”
For those who work out of town or may have other travel commitments they fear may hamper their ability to participate, the program loans Fitbit devices that participants can wear to continue to have their progress tracked and to stay on track while away.
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“We see in real time essentially when they log in for an exercise session, that can be just walking around the block, maintaining their prescription, the heart rate and the time and we gather data that way,” Garrah said.
For Foley, the results have been life-changing.
“(Susan’s) fitness improved 23 per cent,” Garrah said. “She went up a whole category in fitness for her age. Her blood pressure over time improved, her waist circumference lowered, her weight lowered. Susan showed a great result from being in this study.”
Foley is now looking for ways to stay involved with the program because of its life-altering effects.
“What a difference it has made to my health,” she said. “I’ve never been a person who’d exercised ever in my life, and I always knew that it was something that I needed to do. So doing this for the eight months, and I’ll tell you, there were things that happened … losing my son, the side benefit was that I didn’t have the depression. I’m sleeping better. These results and the improvement that I’ve made, it’s just amazing to me that I got so much benefit from doing this program in terms of building muscle, my balance, my heart health, all of the things that I was hoping to get and building exercise into my life and to see the results of doing regular exercise.
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Participation in the study is completely free once selected.
“There is no cost associated at all,” Garrah added.
Garrah also noted that the study focuses solely on health effects of introducing exercise to an otherwise sedentary lifestyle and doesn’t require participants to modify their diets.
“We’re tracking your diet simply to make sure that you’re not upping your caloric intake, or decreasing it,” she said. “There are some people who start and they’re like, ‘Wow, I feel really great, I’m going to lower my caloric intake and try to really lose weight.’ We don’t want you to do that. Any weight loss associated with the study is strictly related to the exercise that you’re doing here.”
To date, Garrah said, 113 participants have completed the study, with the hope being to raise that number to 250 over the next few years. Recruitment is happening now with the goal of adding 40 volunteers to the study before recruiting again in the fall, she added.
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To qualify, you must be between the ages of 25 and 65, have a body mass index of 20 to 40, be weight stable, a non-smoker and non-diabetic, Garrah said. Those who qualify after orientation will undergo all of their assessments on site except for a bone density test, which will be done at Hotel Dieu Hospital.
“Everything assessment-wise and exercise-wise is done here,” Garrah said.
The study’s data will serve two purposes, Dr. Ross said.
“One, that the results will be worth, as we think they will, for publication in a major medical/clinical type journal so the scientific community can see our findings and can say, ‘Boy, that’s great. Where do we go from here? This is very good,’” Ross said. “This extends knowledge. This tells us that it’s a major first step in saying that, as I like to say, maybe there’s not one size that fits all, but everybody has a size.”
And then there is the hope that the work influences public health measures, Ross said.
“There are multiple ways to achieve a benefit,” he said. “We need to tell the scientific community on one end. We also generate guidelines. We do things like that. We take that and we translate that information in a way that the general public will understand it and maybe will help people adopt, sustain and engage in physical activity.”
Interested participants can reach out to Garrah at b.garrah@queensu.ca to inquire.
janmurphy@postmedia.com
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Move more. Sit less. For many years, that’s been accepted guidance for people wanting to get healthier.
Now that message is getting refined, with a growing body of research suggesting that certain types of movements may be more beneficial than others when it comes to health benefits.
The intensity of your exercise may matter as well. A new study published in the European Heart Journal found that a small amount of vigorous activity may be linked to lower risk of eight different chronic diseases.
The findings raise questions about why intensity matters and how people can incorporate more intense exercise routines into everyday life. To better understand the study’s implications, I spoke with CNN wellness expert Dr. Leana Wen, an emergency physician and clinical associate professor at George Washington University. She previously served as Baltimore’s health commissioner.
Before beginning any new exercise program, consult your doctor. Stop immediately if you experience pain.
CNN: What did this study examine about exercise and its relationship to chronic disease?
Dr. Leana Wen: This investigation looked at how the intensity of physical activity is related to the risk of developing a range of chronic diseases. Researchers analyzed data from two very large groups in the UK Biobank, which is a long-term health study in the United Kingdom that tracks medical and lifestyle information from hundreds of thousands of participants. One group included about 96,000 people who wore wrist activity trackers that objectively measured their movement, and the other included more than 375,000 people who self-reported their activity.
The researchers followed participants over an average of about nine years and examined the development of eight conditions: major cardiovascular events, atrial fibrillation, type 2 diabetes, immune-related inflammatory diseases, fatty liver disease, chronic respiratory disease, chronic kidney disease and dementia, as well as overall mortality.
The key finding was that the proportion of activity done at vigorous intensity mattered. People who had more than about 4% of their total activity classified as vigorous had substantially lower risks of developing these conditions compared with people who had no vigorous activity at all. The numbers were stunning, with the participants having the following results:
These results are amazing. Imagine if someone invented a medication that could reduce the risks of all these diseases at once — it would be very popular! Crucially, even people who exercised a lot still benefited if the proportion of time they spent doing vigorous physical activity was increased. Conversely, people who were relatively inactive also benefited from adding just a little bit of higher-intensity exercise to their daily routines.
CNN: What counts as “vigorous” physical activity?
Wen: Vigorous activity is generally defined as exercise that substantially raises your heart rate and breathing. A simple way to gauge it is the “talk test.” If you can speak comfortably in full sentences while exercising, you are likely in the low to moderate range. If you are so out of breath that you can only say a few words at a time, that is vigorous.
Running, cycling, lap swimming or climbing stairs quickly could count. But this also depends on people’s baseline fitness. For some individuals, taking longer strides with walking can be vigorous exercise. Others who are already fairly fit would need to do more. It’s also important to remember that vigorous activity doesn’t have to be in the context of a structured exercise plan. Short bursts of effort in daily life, such as rushing to catch a bus or carrying heavy groceries upstairs, can also qualify if they raise your heart rate and make you breathless.
CNN: Why might higher intensity exercise provide additional health benefits?
Wen: Higher intensity activity places greater demands on the body in a shorter period. This type of movement can improve cardiovascular fitness, increase insulin sensitivity and support metabolic health more efficiently than lower-intensity activity alone. Some studies have also linked vigorous activity with cognitive benefits.
Greater intensity may have distinct benefits across different organ systems. The researchers found that some conditions, such as immune-mediated inflammatory diseases, appeared to be more strongly linked to the intensity of activity than to the total amount. On the other hand, type 2 diabetes and kidney disease were influenced by both how much activity people did and how intense it was. Why this is the case is not yet known, but intensity appears to have a significant impact across diseases affecting multiple organs.
CNN: How much vigorous activity do people need?
Wen: The threshold for people seeing a benefit appears to be relatively low. The researchers found that once people reached more than about 4% of their total activity as vigorous, their risk of developing chronic diseases dropped substantially.
To put that into practical terms, we are not talking about professional athletes dedicating their lives to hours of high-intensity training. Everyday people may see benefits from just doing a few minutes of vigorous effort daily.
CNN: How can people realistically incorporate vigorous activity into their daily routines?
Wen: One helpful way to think practically is that vigorous activity does not have to happen all at once. It can be accumulated in short bursts throughout the day.
People can take the stairs instead of the elevator and do so at a faster pace than usual. When they are heading to work, they can add some speed walking. They can park farther away when grocery shopping and walk briskly while carrying groceries.
Structured exercise also can incorporate intervals where people alternate between moderate and more intense effort. If you’re swimming laps, you can warm up at a more leisurely pace, then do a few laps at a faster pace, then again at a leisurely pace and repeat. This suggestion applies to any other aerobic exercise: Aim for multiple intervals of at least 30 seconds to a minute each where your body is working hard enough that you feel noticeably out of breath.
CNN: What about someone who is older or has mobility issues?
Wen: Not everyone can or should engage in high-intensity activity in the same way. Vigorous activity is relative to that person’s baseline. For someone who is not used to exercise, even a short period of slightly faster walking or standing up repeatedly from a chair could be considered high intensity. And not everyone may be able to walk. In that case, some exercises from the chair can have aerobic benefits.
Individuals who have specific medical conditions should consult with their primary care clinicians before embarking on a new exercise routine. People with mobility issues also may benefit from working with a physical therapist who can help to tailor exercises appropriate to their specific situation.
CNN: What is the key takeaway for people trying to improve their health?
Wen: To me, the main takeaway from this study is that it’s not only how much total exercise you get but also how hard you push yourself that matters. And you don’t have to have a lot of high-intensity exercise: Adding just a little has substantial health benefits across a wide range of chronic health conditions.
At the same time, exercise needs be practical. People should look for opportunities to safely increase intensity in ways that fit their daily lives. The most effective approach to physical activity is a balanced one: Exercise regularly, incorporate more challenging activities when you can and build habits that are sustainable over time.
Get inspired by a weekly roundup on living well, made simple. Sign up for CNN’s Life, But Better newsletter for information and tools designed to improve your well-being.
Ask any exercise scientist what they would prescribe to someone serious about staying strong into their 50s and beyond, and the answer is rarely what you’d hope for — and certainly not what the fitness industry is currently trying to sell you.
It isn’t long sessions on one of the best under-desk treadmills or a stationary bike like the Peloton, nor the kind of machine-based exercises that isolate muscles without ever teaching them to work together.
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Most people are far weaker in this pattern than they realise and it’s exactly why we spoke to leading exercise scientist and functional medicine doctor Pete Williams to find out which single exercise he returns to again and again, why it becomes so critical at this stage of life and how to build it into your routine safely and progressively.
“As we age, our exercise goals should evolve beyond simply lifting heavier weights,” says Williams. “For people over 50, the ability to generate force quickly — known as muscle power — becomes more crucial than maximal strength.” This methodology is exactly why Williams recommends the forward lunge as a key movement pattern for those looking to maintain strength for those in their sixth decade.
This particular focus on power over outright strength is rooted in Williams’ deep understanding of biomechanics. As we age, the ability to produce and maintain power “fundamentally shapes how we move, how we respond to sudden challenges, like trips or slips and how safely we navigate everyday life,” he says, noting that “power declines faster with age than strength alone.”
All of which make the forward lunge the ideal exercise to work on these points, Williams says, as it “builds not just muscle, but neural responsiveness and coordinated control.” By building the functional power to protect against falls and maintain independence in later life, he says, “power and control are the qualities that make movement safe and effective in the real world.”
For Williams, the appeal of the forward lunge isn’t just about building lower-body strength, but also about recruiting and supporting the recruitment of the central nervous system (CNS).
“A forward lunge requires controlled descent into the lunge position, then a powerful push back to standing,” he explains. “This rapid coordination falls under the domain of the CNS, the brain and spinal cord must swiftly sense perturbations and activate muscles to respond.” Simply, by working on muscle power, you can offset the decline that comes with ageing.
Williams points to several everyday scenarios in which the forward lunge can help offset accident risk, including descending stairs, stepping down from curbs and lowering into a chair. “These are not passive movements, as they require muscles to absorb force, decelerate the body, and stabilize joints,” he says. This is called ‘eccentric’ control. Movement patterns that incorporate slow and controlled lowering trains these braking systems, making “accidents on stairs and curbs become far more likely”.
Most of the best smartwatches now come with fall detection, allowing the wearer to send an alert if they fall or have some sort of accident. For older adults, training with forward lunges will reduce the risk of this happening.
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“Strength is a measure of how much force a muscle can produce, whereas power reflects how fast that force can be applied,” says Williams. To illustrate the difference, he describes two people: one who can lift heavy weights slowly, while the other can lift a medium weight faster. “If both trip on an uneven surface, the person with greater power — and thus faster muscle and neural response — is far more likely to catch themselves and avoid a fall”.
This is why Williams argues that exercise programs for older adults must move beyond purely heavy lifting.
Instead, they should incorporate “power training exercises,” such as “faster concentric lifts” and “quick sit-to-stands from a chair,” alongside “functional real-world drills”. This specific focus on “speed and rapid force production” is increasingly recommended for older adults and, according to Williams, “should always be considered.”
Add the lunge into your routine using the instructional video above, and browse our article series The Fit List for more muscle-building and life-lengthening advice.
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Despite being named World Rugby’s Women’s 15s Player of the Year, England rugby star Ellie Kildunne admitted on an episode of Just As Well that the ‘gym was never easy’. In order for her to feel her best, she sticks to a no-nonsense approach to training and nutrition that focuses on the fundamentals: consistent exercise and eating enough.
‘If I haven’t put the work in, if I’ve skipped reps, if I haven’t eaten the right amount for the game, I would feel anxious,’ she says in her cover interview for Women’s Health UK. ‘But I’ve never put myself in that position because I want to be the best.’
What does being the best mean to her? ‘I want to become world player of the year twice. That’s my focus. Anything else that happens is by the by.’
On her episode of Just As Well last year, she said strength training now makes her ‘feel powerful’, while she ‘hates running’ – but a lot of her training involves speed, agility and endurance practice for her time on the pitch. That mix of conditioning and strength means she has built a strong, fast and resilient body.
Speaking of her physical transformation, she admits her personal body image hasn’t always been positive: ‘Body image is such a mental challenge,’ she tells Women’s Health UK. ‘My body is what made me World Player of the Year… I’ve got to remind myself of that.’ Visibility helps too: ‘We’re in that transition phase… social media is starting to lean more towards athletic women… I see people that look like me now.’ Now, Ellie says when she sees a muscular person, she thinks, ‘Respect. Because I know exactly what goes into that.’
As Women’s Health UK’s fitness director and a qualified Pilates and yoga instructor, Bridie Wilkins has been passionately reporting on exercise, health and nutrition since the start of her decade-long career in journalism.
After earning a first-class degree in journalism and NCTJ accreditation, she secured her first role at Look Magazine, where she launched the magazine’s health and fitness column, Look Fit, before going on to become Health and Fitness writer at HELLO!
Since, she has written for Stylist, Glamour, Cosmopolitan, Marie Claire, Elle, The Metro, Runner’s World and Red. Today, she oversees all fitness content across Women’s Health online and in print, spearheading leading cross-platform franchises, such as ‘Fit At Any Age’, which showcases the women proving that age is no barrier to exercise.
She has also represented the brand on BBC Radio London, plus various podcasts and Substacks – all with the aim to encourage more women to exercise and show them how. Outside of work, find her trying the latest Pilates studio, testing her VO2 max for fun (TY, Oura), or posting workouts on Instagram.
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