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Tuberculosis outbreak linked to prominent high school, officials investigating

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Tuberculosis outbreak linked to prominent high school, officials investigating

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An outbreak of tuberculosis (TB) has been linked to a San Francisco high school.

The San Francisco Department of Public Health (SFDPH) issued a health advisory on Jan. 29 about the outbreak, which has been tied to Archbishop Riordan High School.

TB is a curable bacterial infection that targets the lungs, but can also infect other organs, according to Johns Hopkins. It is an airborne contagion that can be spread through coughing, sneezing or saliva.

Three active TB cases have been diagnosed among people associated with Archbishop Riordan High School since November 2025, according to the advisory, and over 50 latent TB infections have been identified within the school community.

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A person with a latent infection has been infected with the tuberculosis bacteria, but the bacteria are inactive in the body.

While latent-stage TB is not contagious, it can develop into active disease in 5% to 10% of people.

An outbreak of tuberculosis (TB) has been linked to a San Francisco high school (not pictured). (iStock)

“Efforts are underway to assure preventive treatment for all these individuals,” the advisory states. 

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The school’s staff and students have been instructed to stay home if they are sick and to get medical clearance from a doctor before returning.

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“Additionally, TB evaluation is required for all students and staff affiliated with the school, regardless of symptoms,” the advisory stated. “Repeat TB assessment will be required every eight weeks until the outbreak is resolved.”

“At this time, risk to the general population is low, so these measures are not needed for patients who are not connected to the AHRS outbreak.”

“If you breathe, you can catch TB — so all people are at risk.”

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In the U.S., more than 565 people died from TB in the most recent complete year of official data available, according to the Centers for Disease Control and Prevention.

There is a greater than 10% case fatality rate in San Francisco, per health officials.

Symptoms, diagnosis and treatment

While around 25% of people have likely been infected with the TB bacteria, just 5% to 10% will experience symptoms and develop the disease. Only people with symptoms are contagious.

Those who get sick with TB may experience mild symptoms, including coughing, chest pain, fatigue, weight loss, weakness, fever and night sweats, according to the CDC.

TB is a curable bacterial infection that targets the lungs, but can also infect other organs, according to Johns Hopkins.  (Spencer Platt/Getty Images)

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In addition to the lungs, the disease can also affect the kidneys, spine, skin and brain.

“TB can affect any organ of the body, but it causes disease in the lung in over 80% of cases,” Masae Kawamura, M.D., a former TB control director in San Francisco and a tuberculosis clinician, previously told Fox News Digital. “This is dangerous because it causes cough, the mechanism of airborne spread.”

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In more severe cases, patients may cough up blood, noted Kawamura, who serves on the board of directors of Vital Strategies, a global public health organization. 

“Often, there are minimal symptoms for a long time and people mistake their occasional cough with allergies, smoking or a cold they can’t shake off,” she added.

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A person with a latent infection has been infected with the tuberculosis bacteria, but the bacteria are inactive in the body. (Janice Carr/CDC/AP)

TB can be identified with rapid diagnostic tests. The disease is treated with antibiotics that are taken every day for four to six months, the CDC states. Some of the most common include isoniazid, rifampicin, pyrazinamide and ethambutol.

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Failing to take the complete course of medications can cause the bacteria to become drug-resistant, which would then require treatment with different medications.

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If TB goes untreated, it is fatal in about half of its victims, according to Kawamura. “About 25% recover on their own and another 25% persist as chronic active TB cases,” she said.  

Who is at risk?

“If you breathe, you can catch TB — so all people are at risk,” said Kawamura, who calls TB a “social disease of crowding and mobility.” 

“Since TB is airborne, congregate settings like hospitals, nursing homes, prisons, jails, classrooms and homeless shelters are places TB is more easily spread, especially if multiple risks are involved,” she added.

Those at the highest risk of developing TB disease after exposure include people who have diabetes, have weakened immunity, are malnourished, use tobacco and/or drink excess amounts of alcohol.  (iStock)

Those at the highest risk of developing TB disease after exposure include people who have diabetes, have weakened immunity, are malnourished, use tobacco and/or drink excess amounts of alcohol. Babies and children are also at higher risk.

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The best means of prevention is testing those at risk and treating latent tuberculosis infection, according to the doctor.

Fox News Digital reached out to Archbishop Riordan High School requesting comment.

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Doctors warn of ‘looksmaxxing’ dangers after influencer’s livestream emergency

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Doctors warn of ‘looksmaxxing’ dangers after influencer’s livestream emergency

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“Clavicular,” the controversial “looksmaxxing” influencer, was reportedly hospitalized due to a suspected overdose Tuesday night during a livestream. 

The Miami content creator, 20, posted a photo of his bloody face and commented on X Wednesday.

“Just got home, that was brutal. All of the substances are just [to] cope, trying to feel neurotypical while being in public, but obviously, that isn’t a real solution. The worst part of tonight was my face descending from the life support mask.”

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The influencer, whose real name is Braden Peters, was hospitalized after his livestream was cut short when he began slurring his words and repeating phrases, according to reports.

What is ‘looksmaxxing’ and why is it trending?

Looksmaxxing is a social media trend focused on enhancing appearance, ranging from basic skin care to extreme practices like hitting cheekbones with hammers to alter facial structure.

Looksmaxxing is a social media trend focused on enhancing appearance, ranging from basic skin care to extreme practices like hitting cheekbones with hammers to alter facial structure. (iStock)

The potentially dangerous trend has been popular with young males, plastic surgeons told Fox News Digital.

“In my practice, we’ve seen it primarily in young men in their 20s,” Dr. Josef Hadeed, a plastic surgeon in Beverly Hills, California, told Fox News Digital. “We have had a few women, but I’d say by and large, it’s been mostly men who have come into our office wanting these various looksmaxxing procedures.”

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“Patients are increasingly seeking to align how they look with how they feel,” he said. “The difference today is that the tools and technologies available to achieve that have never been more advanced or more accessible.”

Looksmaxxing can be divided into two categories: “softmaxxing” and “hardmaxxing,” according to Hadeed. Softmaxxing is a more simple, non-invasive approach to improving one’s looks.

The potentially dangerous trend has been popular with young males, plastic surgeons told Fox News Digital. (iStock)

“It’s really like self-care or grooming – things like going to the gym on a regular basis to try to improve your body composition, or using various skincare products to try to improve your skin texture,” the surgeon said.

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Softmaxxing techniques – which can also include teeth whitening, beard grooming, or upgrading a wardrobe or hairstyle – are not usually a problem, according to Hadeed. Hardmaxxing, which involves more extreme measures, can have riskier consequences.

“Even minimally invasive treatments carry real risks if performed incorrectly or by an untrained provider.”

Some individuals in the looksmaxxing online community do things like “bone smashing,” Hadeed said.

“[It’s] literally what it sounds like, where you smash the bones to change the facial structure, and that is obviously not recommended because it can lead to potential complications,” he warned.

“Once you cross that line and start getting into more extreme things, I feel like that’s where most plastic surgeons should draw the line.”

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Dr. C. Bob Basu, president of the American Society of Plastic Surgeons, said the biggest safety risks with the looksmaxxing trend come from pursuing treatments without proper medical guidance.

Looksmaxxing can be divided into two categories: “softmaxxing” and “hardmaxxing.” Softmaxxing is a more simple, non-invasive simple approach to improving one’s looks. (iStock)

“Social media can make procedures seem easy or risk-free, but even minimally invasive treatments carry real risks if performed incorrectly or by an untrained provider,” the Houston-based plastic surgeon told Fox News Digital.

To achieve quality results, it is critical to be treated by a board-certified plastic surgeon who understands both safety and anatomy, Basu advised.

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What’s driving the trend?

The convergence of social media, constant digital visibility and “unprecedented access to aesthetic treatments” – along with a cultural shift toward optimizing wellness and longevity – are fueling the looksmaxxing trend, according to Basu.

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Hadeed agreed, noting that social media puts pressure on individuals to look perfect.

“People are constantly comparing themselves to other people online,” he told Fox News Digital. “It can quickly develop into body dysmorphia for a lot of people, and that’s when they start pursuing more and more procedures that they don’t need by any stretch – it’s kind of like keeping up with the Joneses.”

Both plastic surgeons emphasized the importance of taking a responsible approach when considering the looksmaxxing trend. (iStock)

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Dr. Nancy Frye, a professor in the psychology department at Long Island University in Brookville, New York, also weighed in on what’s driving the looksmaxxing craze.

“We figure out how attractive we might be by comparing what we see in ourselves to what we see in others,” she told Fox News Digital. “This social comparison is especially problematic with social media and filters, as people compare themselves to filtered versions of others.”

Healthier approach

While experts warn of the risks of looksmaxxing, they say a thoughtful approach can have some benefits, including pride in one’s appearance and health.

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The most tangible benefits are associated with the softmaxxing approach, which includes following a fitness routine, eating a clean diet and following regular skin care routines, according to Hadeed.

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“The goal should always be thoughtful self-improvement, not perfection.”

With healthy guidance, aesthetic care can “enhance confidence and self-esteem, helping patients feel more aligned with their sense of self,” Basu added.

Both plastic surgeons emphasized the importance of taking a responsible approach when considering the looksmaxxing trend.

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“The goal should always be thoughtful self-improvement, not perfection,” Basu said. “It should never be about looking like someone else or a filtered version of yourself, but rather about becoming a confident, natural and authentic version of you.”

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Anyone considering this trend should consult a licensed healthcare professional rather than relying on advice from social media influencers, the doctors advised.

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Peptides may soon be easier to get amid RFK Jr’s push, but experts warn of risks

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Peptides may soon be easier to get amid RFK Jr’s push, but experts warn of risks

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The Food and Drug Administration (FDA) will reportedly weigh easing restrictions on peptides in anticipated talks.

The meeting, which is expected to be held in July, will discuss relaxing limits on more than a half dozen peptide injections.

Peptides are short chains of amino acids — the building blocks of proteins — that play key roles in biological functions, according to the National Institutes of Health. Peptide drugs are lab-made versions of natural molecules in the body that are designed to mimic or influence biological signals to treat disease, experts say.

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In a federal notice released Wednesday, the FDA identified these drugs — used for conditions ranging from insomnia to obesity — for potential inclusion on a list of substances that can be safely compounded by pharmacies.

Human Services Secretary Robert F. Kennedy Jr. does pull-ups during a conference at Ronald Reagan Washington National Airport in Arlington, Va., on Dec. 8, 2025, discussing the launch of the “Make Travel Family Friendly Again” campaign. (Heather Diehl/Getty Images)

This follows Health and Human Services Secretary Robert F. Kennedy Jr.’s push to deregulate peptides, which he’s spoken about publicly, although most peptides have not been reviewed for safety by the FDA.

Kennedy has discussed using the substances for personal injuries. In a recent interview on “The Joe Rogan Experience” podcast, he stated that he’s a “big fan of peptides.”

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The HHS secretary mentioned that he’s “very anxious” to making some peptides “more accessible.”

“My hope is that they will get moved to a place where people have access from ethical suppliers,” Kennedy said, alluding to the FDA taking action.

What to know about peptides

Peptides have gained popularity among wellness influencers and fitness gurus as a means of building muscle, healing injuries or appearing younger, the AP reported.

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Peptides act like a signal to hormones and the human body. Similar to how GLP-1s (glucagon-like peptide-1 agonists), such as Ozempic, suppress appetite and trigger weight loss, peptides can signal other functions, like the release of growth hormones.

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Peptides have gained popularity for outcomes like building muscle, healing injuries or appearing younger, the AP reported. (iStock)

Certain peptides up for review by the FDA, like BPC-157, are marketed for tendon healing, gut healing (in cases like ulcerative colitis), injury recovery and inflammation reduction, although the FDA has warned about the risk of unapproved peptide treatments.

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The FDA wrote in a February advisory that “compounded drugs should only be used in patients whose medical needs cannot be met by an FDA-approved drug.”

“Patients should obtain a prescription from their doctor and fill the prescription at a state-licensed pharmacy,” the agency wrote.

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The FDA wrote in a February advisory that “compounded drugs should only be used in patients whose medical needs cannot be met by an FDA-approved drug.” (Sarah Silbiger/Getty Images)

The current peptide market has been referred to as the “Wild West” due to lack of regulation. In an interview with AP, Dr. Peter Lurie, a former FDA official who now leads the Center for Science in the Public Interest in Washington, D.C., commented that “the Wild West is about to become wilder.”

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“I don’t see why one would take the path of proper drug approval if there is now this less rigorous, alternative path to market,” he said.

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Under the Biden administration, the FDA added nearly 20 peptides to a list of substances that should not be produced by compounding pharmacies, according to the AP.

The panel of pharmacy advisers at the time noted that the peptides did not meet criteria for safety.

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This could be why your weight-loss medication isn’t delivering results

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This could be why your weight-loss medication isn’t delivering results

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The skyrocketing popularity of GLP-1 receptor agonists has transformed the weight-loss industry, but not all shots are created equal in terms of how they work.

A study published in Nature investigated how genes affect the success of modern weight-loss drugs — specifically, GLP-1s like semaglutide and tirzepatide.

In analyzing genetic data and self-reported weight loss from over 27,000 users, researchers pinpointed a specific variation in the GLP-1 receptor gene (GLP1R) that acts as a “booster” for the drug’s effectiveness.

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Individuals carrying one copy of this variant lost an average of 1.6 pounds more than those without it, according to the findings.

This suggests that genetic testing could eventually help doctors steer sensitive patients toward medications they are more likely to tolerate.

Individuals carrying one copy of a specific genetic variant lost an average of 1.6 pounds more than those without it. (iStock)

“We believe these reports are a step forward in meeting an unmet need for a more informed and personalized approach to weight management,” said study co-author Noura Abul-Husn, chief medical officer at the 23andMe Research Institute in California, in a press release.

While this genetic “boost” is measurable, it remains relatively modest when compared to the total average weight loss of 24 pounds observed across the study population, the researchers noted.

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Beyond genetics, other factors such as age, sex and specific medications remain much stronger predictors of success.

For instance, the study found that women generally saw a higher body mass index (BMI) reduction (12.2%) compared to men (10.0%).

Traditional factors such as age, sex and specific medications remain much stronger predictors of success. (iStock)

The study may also reveal why certain patients experience stomach issues. Scientists identified a different genetic variant that was linked to increased reports of nausea and vomiting.

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The presence of this side effect did not impact the drug’s effectiveness, however. Patients with variants in the GLP1R and GIPR genes lost just as much weight as those without it; they simply felt more sick during the process, the study found.

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“GLP-1 treatment decisions are complex, and having access to clinical expertise to help contextualize your genetic results alongside your full health picture is exactly the kind of guidance this report is designed to support,” said Abul-Husn.

Patients with the variant lost just as much weight as those without it; they simply felt more sick during the process, the study found. (iStock)

Dr. Peter Balazs, MD, a hormone and weight-loss specialist serving the New York and New Jersey area, was not involved in the study but reiterated the role of the genetic variants in treatment response and side effects.

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“Notably, there appears to be a drug-specific effect: The GIPR variant associated with these side effects is observed with tirzepatide, but not with semaglutide,” he told Fox News Digital.

Balazs said he was surprised by the extremely wide nausea risk range (5%–78%). “Additionally, the drug-specific genetic dissociation was unexpected,” he added.

Study limitations

The data relied on participants reporting their own weight, which could be subject to bias.

“The data is self-reported and not medically verified, which may affect its reliability firstly,” Balazs told Fox News Digital. “It also does not account for key treatment variables, such as titration, discontinuation or dosing schedules.”

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The 23andMe participant pool may not reflect a diverse, real-world population, he added.

“The study also lacks data on important clinical endpoints, such as diabetes progression, and severe adverse effects, such as gastroparesis or pancreatitis,” Balazs pointed out. “Many of its findings also have not been supported by more clinically and statistically robust studies.”

Patients with the variant lost just as much weight as those without it; they simply felt more sick during the process, the study found. (iStock)

For example, a sub-study comparing these reports to objective iPhone health data suggested that participants might over-report their progress. While users reported an 11.8% loss, electronic data in that subset showed a 5.8% loss.

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As an observational study rather than a controlled clinical trial, it could not definitively prove that the genetic variants caused the difference in weight loss, only that they are associated with it, the researchers noted.

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“I think this article is interesting, raising the possibility of genetic factors, and the use of genetic testing incorporated into further decision-making when picking weight-loss medications,” Balazs said. “However, I would be careful to draw conclusions solely based on this study.”

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