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How Measles Attacks an Unvaccinated Child

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How Measles Attacks an Unvaccinated Child

For a child who is not vaccinated against measles — one of the world’s most infectious viruses — no classroom, school bus or grocery store is safe. Nine out of 10 unvaccinated people exposed to an infected person will catch it, and once measles takes root, the virus can damage the lungs, kidneys and the brain.

With falling U.S. vaccination rates and outbreaks that have caused more than 580 cases and at least one death, health experts expect measles to infect hundreds or even thousands more across the nation. Here is how measles takes over the body.

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Unlike viruses that require person-to-person contact, measles lingers in the air for up to two hours after the person carrying it has left the space.

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Droplets are enlarged for illustration purposes.

A child can inhale virus-containing droplets in a room where another child — unknowingly infected with measles — has been studying or playing an hour earlier. The virus can enter her body through the lining of her nose or mouth, or when she’s rubbing her eyes.

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During the subsequent 24 hours, the virus takes root by lodging in her nasopharynx cells in the upper part of the throat and starts spreading to her lungs.

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Then, the virus takes over, multiplying inside the cells and building up an army for an attack.

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Within a few days, the virus begins to spread to infect the nearby lymphoid tissues. About a week after the initial exposure, infected cells begin traveling to other organs throughout the body. (At this time, the immune system of a vaccinated child would recognize the virus and fight it off.)

Typically, during the replication and spread of the virus, the child does not feel sick. The average incubation period is about two weeks — though it can range from one to three. When the viral load has increased significantly, it moves to infect other cells of the lungs and eyes, making the child feel ill.

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A couple of weeks after the unvaccinated child inhales the droplets, she starts feeling sick.

Children often first show signs of malaise and a fever, followed later by reddish, irritated eyes, a cough and a stuffy nose as the mucus membranes and nasal passages become inflamed.

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Some children at this stage develop millimeter-wide, whitish-gray bumps on the inner lining of the cheeks, as far back as the molars. For some, the spots go undetected, or do not show up at all.

Then comes the characteristic feature: the breakout of a red rash, starting on the face and spreading down the neck, trunk, and extremities.

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Many of these symptoms should resolve themselves. The rash can last up to a week, often fading along the same route it appeared. The cough can last for up to two weeks after the illness has resolved. But a fever lasting beyond the third or fourth day of the rash suggests that a complication could be developing — and that is where cases can become dangerous.

Even as the rash fades, the infection can spread to the lungs and other organs.

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Children are typically brought to the hospital after having the body rash for several days. Most have low oxygen levels and are laboring to breathe and need support, said Dr. Summer Davies, who sees children at Covenant Children’s Hospital in Lubbock, Texas, and has been treating measles cases there since the outbreak started in late January.

“A lot of families have kind of been surprised, like, ‘Oh, my child was fine, and then all of a sudden, they’re not,’ ” she said.

That mild disease evolves into a fever as high as 104 or 105 degrees for two, three or four days. Poor fluid intake, a sore throat and diarrhea can lead to dehydration, which over time can begin to threaten kidney function.

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Young children are more at risk because of their smaller anatomy and their inability to articulate symptoms clearly, explained Dr. Lara Johnson, the chief medical officer of a group of Covenant hospitals in the area.

About one in 20 children with measles will develop pneumonia, an infection in the lungs; and severe cases can be fatal.

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Dr. Davies said many children admitted to her hospital recently had cases of pneumonia caused by either the measles virus or by a second pathogen that attacked while their immune systems were weakened.

The 6-year-old girl who recently died of measles in Texas had a case of pneumonia that caused fluid to build up in her left lung, making it difficult for her to breathe, according to a video interview with her parents that was posted online. She was eventually sedated and intubated, but she became too sick to survive.

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One of the hallmarks of measles is what researchers call “immune amnesia,” the temporary weakening of the immune system. Measles wipes the protection children have acquired from other infections, which leaves them susceptible to other infections for several months or even years.

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Inflammation in the brain

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About one in 1,000 children who contract measles will also develop encephalitis, or inflammation of the brain tissue, which can result in permanent damage.

For infants or children who are already immunocompromised, a condition called measles inclusion body encephalitis (or MIBE) occurs when the child cannot clear the infection. It can trigger mental changes and seizures, leading to a coma and death in most patients.

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Another type, called subacute sclerosing panencephalitis (SSPE), is a degenerative condition that can occur up to a decade after a measles infection. Children often first show signs of behavior change and academic decline, followed by seizures, motor issues like poor coordination and balance, and eventually death. The mortality rate approaches 95 percent.

Erica Finkelstein-Parker, a mother in Pennsylvania who lost her 8-year-old child Emmalee to the condition, had not known that the girl had had measles before she had been adopted from India as a toddler. But she noticed one day that Emmalee was tripping and falling, slumping over to one side of her chair and struggling to lift her chin off her chest during dinner.

Doctors explained that there was no cure. Emmalee passed away about five months later.

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Americans wait overnight for access to free healthcare as costs soar ‘out of reach’

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Americans wait overnight for access to free healthcare as costs soar ‘out of reach’

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The Trump administration’s recent pullback on health insurance has left fewer Americans with coverage.

For the uninsured, being treated for certain conditions may be out of the question due to high costs.

This has led some Americans to wait multiple days, some even sleeping overnight in their cars, to seek free free healthcare from volunteer clinics like Remote Area Medical (RAM).

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The Tennessee-based nonprofit organization, founded in 1985, employs volunteer healthcare professionals to treat Americans without insurance at no cost.

In a recent episode of CBS News’ 60 Minutes, host Scott Pelley spoke with people waiting to be brought into the clinic.

Medical professionals from all around the U.S. volunteer their time at Remote Area Medical (RAM) clinics. (Remote Area Medical)

In February, Sandra Tallent drove 200 miles from Huntsville, Alabama, to RAM’s pop-up clinic in Knoxville, Tennessee, to have her teeth examined.

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She arrived at the clinic site at 4:30 p.m. on Wednesday and spoke to Pelley from her car at 5 a.m. Friday, after sleeping for two nights in the parking lot.

Pelley asked, “If you didn’t have RAM, how would you get your teeth taken care of?” Tallent responded, “I wouldn’t.”

Some Americans have been waiting hours and even sleeping overnight in their cars to be seen by a doctor. (iStock)

Tallent was later seen by a dental expert and had dentures created in RAM’s 3D denture-printing lab.

Connor Gibson, a 22-year-old engineer, uses computer design to get the job done in just about an hour, according to the report. This is a process that can typically take weeks.

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“We see grown men cry sitting in the chair,” Gibson told 60 Minutes, describing what it’s like for patients to see themselves with a new set of teeth for the first time.

This includes Tallent, who looked in the mirror and smiled with tears in her eyes, expressing her gratitude.

Remote Area Medical clinic volunteers and patients are pictured at the center in Tennessee. RAM has recently expanded its services to include women’s health exams, general wellness check-ups and sports physicals.  (Remote Area Medical)

In an interview with Fox News Digital, RAM CEO Chris Hall shared how their clinics pop up and move across the country to expand access for more Americans.

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“All of our services are provided free of cost to patients on a first come, first serve basis,” he said. “And we do that through our team of dedicated volunteers and professionals that come from all around the county.”

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RAM provides cleanings, fillings and extractions, as well as comprehensive eye exams and access to an eyeglass lab that can manufacture eyewear and dentures, according to Hall.

About 60% of patients seek dental care, he said, and about 30% to 35% seek vision care.

RAM provides cleanings, fillings and extractions, as well as comprehensive eye exams and access to an eyeglass lab that can manufacture eyewear and dentures. (iStock)

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RAM has recently expanded its services to include women’s health exams, general wellness check-ups and sports physicals. 

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In 2008, RAM held about 10 to 12 events per year. Today, it has grown to 90 full-scale operations, with events happening nearly every weekend, Hall shared.

Hall said the demand for medical care has been consistent for the last 20 years. Even for some patients who have insurance, the out-of-pocket premiums and deductibles can be “out of reach.”

Chris Hall, CEO of Remote Area Medical, describes the operation as “inspiring, yet heartbreaking.” (Remote Area Medical)

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“The communities that we go into, the patients who are coming through our door, these are working-class people,” Hall said.

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“Whether we’re doing events in rural Appalachia or downtown Los Angeles, the patients who are coming … they’re just isolated and do not get the care that they need,” he added.

Hall said he’s heard “heartbreaking” stories from patients who have put off medical care to keep the lights on in their homes and provide food for their families.

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Marriage status has surprising link to cancer risk, study suggests: ‘Clear signal’

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Marriage status has surprising link to cancer risk, study suggests: ‘Clear signal’

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Adults who never married are significantly more likely to develop cancer, according to new research from the University of Miami.

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A large study of more than 4 million Americans across 12 states found that this increased risk spans nearly every major cancer type. It is especially true for preventable cancers, such as types caused by smoking and infection.

Men who never married were found to have a 70% higher likelihood of cancer than their married counterparts. For women, that gap was even wider, with never-married individuals facing an 85% higher risk.

EATING MORE OF CERTAIN TYPE OF FOOD COULD SHORTEN CANCER SURVIVORS’ LIVES, STUDY FINDS

Previous research has linked marriage to better survival rates after a diagnosis, but this is one of the first studies to show that marital status could be a major indicator of whether a person will develop cancer in the first place.

“These findings suggest that social factors such as marital status may serve as important markers of cancer risk at the population level,” study co-author Paulo Pinheiro, a research professor of epidemiology at the University of Miami Miller School of Medicine, said in a press release.

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Adults who never married are significantly more likely to develop cancer, according to new research from the University of Miami. (Getty Images)

Between 2015 and 2022, the team examined cancer cases diagnosed at age 30 or older and compared the rates of various cancers to the marital status of participants. They then broke down the data by sex and race and adjusted for age.

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Adult men who were never married had approximately five times the rate of anal cancer compared to married men, the study found.

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Adult women who were never married had nearly three times the rate of cervical cancer compared to women who were or had been married.

“It’s a clear and powerful signal that some individuals are at a greater risk,” Frank Penedo, director of the Sylvester Survivorship and Supportive Care Institute at the University of Miami, said in the release.

For women, being married (and often, by extension, having children) was associated with lower risks of ovarian and endometrial cancers. (iStock)

For women, being married (and often, by extension, having children) was associated with lower risks of ovarian and endometrial cancers, likely due to hormonal and biological factors associated with pregnancy, according to the researchers.

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Experts stressed that these findings do not mean marriage alone can protect against cancer.

“It means that if you’re not married, you should be paying extra attention to cancer risk factors, getting any screenings you may need, and staying up to date on healthcare,” Penedo said.

Experts stressed that these findings do not mean marriage alone can protect against cancer. (iStock)

The researchers also hypothesized that people who smoke less, drink less and take better care of themselves may be more likely to get married, meaning other factors could influence the findings.

More research is needed to confirm the outcome, they noted.

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The study was published in the journal Cancer Research Communications.

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This everyday drinking pattern could quietly raise liver disease risk

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This everyday drinking pattern could quietly raise liver disease risk

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Widespread drinking habit could triple risk of advanced liver condition

Deadly bacterial disease could be stopped by pantry staple

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Even occasional binge drinking could triple the risk of a serious liver condition, a new study suggests. (iStock)

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