Health
A Federal Lab That Tracked Rising S.T.I.s Has Been Shuttered
Drug-resistant gonorrhea, a form of the widespread sexually transmitted infection, is considered an urgent health threat worldwide. The United States has just lost its ability to detect it.
Among the Centers for Disease Control and Prevention employees fired on Tuesday were 77 scientists who, among other work, gathered samples of gonorrhea and other S.T.I.s from labs nationwide, analyzed the genetic information for signs of drug resistance, and readied the samples for storage at a secure facility.
No other researchers at the agency have the expertise, or the software, to continue this work. The abrupt halt has stranded about 1,000 samples of gonorrhea and other sexually transmitted pathogens that had not yet been processed, and perhaps dozens more headed to the agency.
There are as many as 30 freezers full of samples that now have no custodians, said one senior C.D.C. official who spoke on condition of anonymity for fear of retaliation.
“We were just really shut down midair, like there was no warning,” the official said. “It was just completely unplanned and chaotic.”
The C.D.C.’s work on S.T.I.s had taken on greater urgency in the past few years as rates of new infections soared. More than 2.4 million new S.T.I.s were diagnosed in 2023, about one million more than 20 years ago.
Nearly 4,000 babies were born with congenital syphilis in 2023. About 280 were stillborn or died soon after.
“Whoever got rid of the lab just doesn’t understand how important the lab is,” said another senior C.D.C. official who spoke on condition of anonymity.
About 600,000 new gonorrhea cases were diagnosed in the United States in 2023. The bacteria that cause gonorrhea, called Neisseria gonorrhoeae, spread through sexual contact to the genitals, rectum and throat. Left untreated, it can cause infertility and sterility, blindness in infants or even death.
Gonorrhea has become resistant to nearly every available antibiotic, leaving a single class that still snuffs it out. The most powerful defense combines a shot of ceftriaxone with azithromycin, but some evidence hints that gonorrhea is evolving to sidestep even that treatment.
Over more than 25 years, the C.D.C. lab archived about 50,000 gonorrhea samples — the largest collection in the world — which allow scientists to track how the pathogen has changed over time. It’s not clear what will happen to the samples.
One new public health strategy makes it even more important for the nation to track gonorrhea, said Dr. Jenell Stewart, an infectious diseases physician at Hennepin Healthcare in Minneapolis.
In a bid to combat resurgent syphilis and chlamydia, the C.D.C. recommended last year that gay and bisexual men and transgender women take doxycycline, a widely used antibiotic, within 72 hours of unprotected sex.
Cities like San Francisco and Seattle that had earlier endorsed the practice, called doxy-PEP, have already seen drastic drops in the rates of those infections.
But researchers are worried that widespread use of doxycycline might increase resistance to the entire class of antibiotics, called tetracyclines. A few studies suggest there may be reason to worry.
Harvard University researchers last month analyzed more than 14,000 genetic sequences generated by C.D.C. researchers and found that the proportion of gonorrhea bacteria with antibiotic resistance increased to more than 35 percent last year, from less than 10 percent in 2020.
The federal scientists who produced that data and made it publicly available have all been fired. “Without public health money and infrastructure, I’m not sure who if anyone will take up the torch to monitor gonorrhea resistance,” Dr. Stewart said.
“This is a huge loss,” she added.
Dr. Stewart and a colleague spent two years preparing the protocol and an app to study doxy-PEP in cisgender women and monitor gonorrhea resistance.
The study was supported by the Adolescent Medicine Trials Network, whose funding was slashed last month.
At least five other grants to study doxy-PEP have been terminated, along with a variety of grants at the National Institutes of Health aimed at preventing S.T.I.s, including H.I.V.
Any lab can test for S.T.I.s, but commercial tests cannot determine whether gonorrhea will respond to available treatments. C.D.C. scientists developed the only such test, and provided funding and training to a few dozen labs on the sophisticated testing.
Samples were sent to the agency for confirmation. Without the agency scientists, testing for drug sensitivity will most likely cease, several experts said.
“We cannot have a national surveillance system without a national lab,” said one scientist who leads a C.D.C.-funded lab but did not wish to be identified without authorization to speak to the media.
C.D.C. scientists were also helping to develop alternatives to the nation’s outdated syphilis test. It cannot identify an active infection, only whether someone was ever infected. The agency has three large contracts to develop new rapid syphilis tests.
But without expertise and the samples from C.D.C. scientists, it’s unclear whether that work can continue, said a senior official with knowledge of the situation.
The fired scientists had about 1,400 years of field experience between them. The official said, “These were highly trained people that are not replaceable easily.”
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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More than three million people travel to undergo cosmetic surgery each year, statistics show — but the potential savings come at a cost.
Most people opting to pursue this so-called “medical tourism” are chasing budget-friendly price tags.
International surgeries, such as hair transplants in Turkey, can cost as little as $4,000 to $5,000 compared to $20,000 to $30,000 in the U.S., but often come with extreme risks, according to board-certified plastic surgeon Dr. Sheila Nazarian of California.
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The doctor recently joined Lisa Brady on the “The FOX News Rundown” podcast to discuss the rising trend of medical tourism. One of the biggest risks, she said, is the lack of safety regulations in popular destinations like Mexico and Turkey.
As demand spikes in these medical tourism “mills,” there have been reports of non-medically trained staff performing procedures like hair transplants.
Most people opting to pursue “medical tourism” are chasing budget-friendly price tags. (iStock)
“I’ve heard that they [international clinics] are even recruiting people who maybe were taxi drivers and then putting them through their own training program … to become hair transplant technicians,” Nazarian said. “That’s how high the demand has become.”
In the U.S., medical school graduates are granted a “physician and surgeon” license, which means doctors — including pediatricians or OB-GYNs — can legally perform cosmetic surgeries, even if they didn’t receive specialized training for those procedures during residency, Nazarian noted.
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Instead of pinching pennies, the doctor recommended paying whatever amount is necessary to ensure quality treatment.
“People think of it as, you know, going to the mall. … It’s surgery, and surgery has risks,” she said. “You need to be with someone who not only can perform a beautiful surgery, but who can handle possible complications well.”
“You need to ask them: ‘What was your residency training in? And if you wanted to, would you be allowed to do this procedure in a hospital?’”
Aftercare is another critical factor in the success and safety of a cosmetic procedure, as the doctor emphasized that 20% of a surgical result depends on post-operative care.
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This can be difficult or even impossible to manage when a doctor is in a different time zone, she cautioned, or if the clinic disappears shortly after the procedure.
Nazarian also noted the importance of addressing the psychological component of plastic surgery, noting that no procedure will fix underlying unhappiness. The doctor said she uses screening questionnaires to ensure that patients are truly seeking self-improvement rather than a “cure” for deeper issues.
International surgeries, such as hair transplants in Turkey, can cost as little as $4,000 to $5,000 compared to $20,000 to $30,000 in the U.S., but often come with extreme risks. (iStock)
“If you’re not already generally very content with your life, a knife in my hand is not going to bring you there,” Nazarian said.
“The analogy I always give is you don’t want a paisley couch — you want a neutral couch and you can put paisley pillows on it,” she said, noting that a procedure should “make you look normal, God-given, athletic. And then you can change your clothes when the trends come and go.”
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Samuel Golpanian, M.D., a double board-certified plastic surgeon in Beverly Hills, said he has also seen an increasing number of patients undergoing cosmetic procedures abroad, sometimes with “devastating consequences.”
“The key is being extremely careful before embarking on this journey.”
“I’ve seen a wide range of complications, including infections, poor wound healing, significant scarring and tissue necrosis (skin death),” he told Fox News Digital. “These complications often lead to prolonged pain, ongoing medical problems, and significant additional costs to repair the damage.”
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Golpanian said he’s treated patients who received unsafe or non-medical-grade injectable materials, which can lead to serious long-term health issues.
One surgeon said he’s treated patients who received unsafe or non-medical-grade injectable materials, which can lead to serious long-term health issues. (iStock)
“I’ve also seen damage to underlying structures, asymmetry and results that are extremely difficult — sometimes impossible — to correct.”
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“That said, I’ve also seen some good outcomes, so it’s not all bad,” he noted. “The key is being extremely careful before embarking on this journey.”
Quick tips for safe ‘medical tourism’
Fully vet the surgeon. “Most surgeons will provide information about their education and training, but it’s important not to accept these claims at face value,” Golpanian said. “Verify them directly by contacting the institutions where they trained.”
Ask for references from prior patients. Ideally, it’s best to get references from U.S.-based patients who can speak candidly about both their experience and their results, the surgeonsaid.
Think beyond the cost. Golpanian emphasized the adage “you get what you pay for.” “Cost should take a back seat to experience, training, judgment and proven results,” he advised.
Be cautious about relying on before-and-after photos. These can be selective or even enhanced, Golpanian warned.
Keep aftercare in focus. “Make sure the practice emphasizes comprehensive follow-up care and has a clear, realistic post-operative plan in place.”
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