Health
Diabetes patients now have access to first generic GLP-1 medication: ‘More accessible and affordable’
Ozempic, Wegovy and other GLP-1 medications have gained widespread popularity for weight loss and diabetes control in recent years — but the spike in demand has made it difficult for some people to get the drugs.
To help eliminate supply chain snafus, the first-ever generic GLP-1 — a duplicate of Victoza — launched on June 25.
Manufactured by Novo Nordisk and distributed and sold by Israel-based Teva Pharmaceuticals, Victoza is an injectable medication intended to treat type 2 diabetes. It has also been shown to promote weight loss in certain patients, according to Teva.
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While Ozempic and Wegovy contain semaglutide and Mounjaro has tirzepatide, Victoza has liraglutide as its active ingredient.
“By launching an authorized generic for Victoza (liraglutide injection 1.8mg), we are providing patients with type 2 diabetes another option for this important treatment,” said Ernie Richardsen, SVP, head of U.S. commercial generics at Teva, in a press release from the company.
The first-ever generic GLP-1, a version of Teva Pharmaceuticals’ Victoza, launched in late June 2024. (iStock; Getty Images)
The new authorized generic is the exact same medication as brand-name Victoza, but without the brand name on the label and sold at a lower price point, explained Alyssa Billingsley, PharmD, the senior director of Pharmacy Content at GoodRx in St. Louis, Missouri.
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Just as Wegovy is a higher-dose version of Ozempic to treat obesity, there is a higher-dose version of Victoza — sold under the brand name Saxenda — but a generic version is not yet available.
“This is a positive step forward to making GLP-1 agonist medications more accessible and affordable,” Billingsley told Fox News Digital via email.
Victoza is manufactured by Novo Nordisk and distributed and sold by Israel-based Teva Pharmaceuticals. (Getty Images)
This class of drugs has a growing list of beneficial applications beyond just treating type 2 diabetes, Billingsley noted, but their cost can be a barrier for many people to access them.
“In general, authorized generics are usually priced at a discount, potentially making them a more affordable option for some people,” she said.
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“However, some insurers may still prefer brand-name Victoza, even with a lower-cost authorized generic available.”
Patients should check with their insurance provider to confirm which options are covered and what they can expect to pay, Billingsley advised.
This class of drugs has a growing list of benefits, but cost can be a barrier for some patients. (iStock)
Dr. Brett Osborn, a Florida neurologist and longevity expert, agreed that the availability of the first generic GLP-1 is “great news.”
The generic’s lower price point is particularly beneficial for people who have chronic conditions like diabetes, Osborn noted — “where long-term medication use is necessary to prevent downrange effects like vascular disease, strokes and heart attacks, cancer, neurodegenerative diseases like Alzheimer’s, and obesity, the latter of which is also a ‘gateway disease,’” he said.
Differences between liraglutide and semaglutide
There are some differences between the generic version of Victoza and Ozempic and other GLP-1 agonists, doctors noted.
The new drug’s active ingredient is liraglutide instead of Ozempic’s semaglutide — and it is approved for use in both adults and children age 10 and older who have diabetes.
Semaglutides are not yet approved for children.
While semaglutides like Ozempic are given once each week, liraglutide medications require daily dosing because they have a shorter half-life. (iStock)
There are also dosing differences — while semaglutides like Ozempic are given once each week, liraglutide medications require daily dosing because they have a shorter half-life, the doctor said.
“Each medication has pros and cons,” Osborn said. “At base level, however, the molecules are similar and subserve identical bodily functions — appetite suppression and the promotion of insulin secretion from the pancreas.”
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The most common side effects of liraglutides include nausea, vomiting, diarrhea, decreased appetite, indigestion and constipation, according to the company’s release. Other, more serious side effects are possible.
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Patients who experience adverse or lingering side effects should see a health care provider.
Fox News Digital reached out to Teva Pharmaceuticals and Novo Nordisk for comment.
Health
The Wegovy Pill Is Here: See the Cost and How Much Weight You Can Lose
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Health
Missing sleep may take a hidden toll on your brain and longevity, research reveals
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Missing out on adequate sleep could be taking years off your life.
New research from the Oregon Health & Science University (OHSU), published in the journal Sleep Advances, found that poor sleep may shorten life expectancy more than other lifestyle factors like diet, exercise and loneliness.
The researchers analyzed nationwide CDC survey data, identifying trends associated with average life expectancy by county, according to a press release.
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The study found that lack of adequate sleep led to higher mortality risk in every U.S. state and was the top behavioral driver compared to other factors, only behind smoking.
Senior study author Andrew McHill, Ph.D., associate professor and director of the Sleep, Chronobiology, and Health Laboratory in the OHSU School of Nursing, noted in a statement that he did not expect sleep to be “so strongly correlated” to life expectancy.
Poor sleep is directly correlated with shorter life expectancy, the study reveals. (iStock)
“We’ve always thought sleep is important, but this research really drives that point home: People really should strive to get seven to nine hours of sleep, if at all possible,” he said.
“This research shows that we need to prioritize sleep at least as much as we do [in] what we eat or how we exercise.”
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In a previous interview with Fox News Digital, Dr. Daniel Amen, psychiatrist and owner of Amen Clinics in California, emphasized how important sleep is for brain function and longevity.
Researchers suggest people should prioritize sleep just as much as diet and exercise. (iStock)
“Sleep is so important,” he said. “When you sleep, your brain cleans and washes itself. And if you don’t sleep seven to nine hours at night, your brain looks older than you are — there’s less blood flow, and it increases inflammation in the brain.”
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“Your brain doesn’t have enough time to get rid of the toxins that build up during the day.”
Lack of adequate sleep can lead to poor decisions and foster toxic cycles, the doctor warned.
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“If your brain has less activity in the front part, not only are you tired, but you’re also hungrier, and you’re more likely to not make the best decisions,” he said.
“Which, of course, will stress you out, and then you won’t sleep well the next night.”
A doctor suggests being “purposeful” about going to bed and waking up each day. (iStock)
One small change to promote longevity and brain health is to try getting to bed 15 minutes earlier, Amen suggested.
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“Really be purposeful about not being distracted by Netflix or your phone,” he said.
“And when you get up in the morning, say to yourself, ‘Today is going to be a great day.’ The more positive you are, the better your brain.”
Health
The Best Time To Take ‘Nature’s Ozempic’ Berberine for Weight Loss and Blood Sugar Control, According to an MD
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