Health
Disrupted sleep, plus nightmares could be linked to autoimmune diseases, experts say
Those who experience vivid nightmares and odd hallucinations might have an underlying autoimmune disease, a new study suggests.
An international research team led by scientists at the University of Cambridge and King’s College London explored the potential link between nightmares and hallucinations and systemic autoimmune rheumatic diseases.
The study, published in March in the journal eClinicalMedicine, included 676 people with lupus and 400 people from the medical field, as well as interviews with 69 people living with systemic autoimmune rheumatic diseases, SWNS reported.
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Those with autoimmune diseases were asked about the timing of their neurological and mental health symptoms, such as disrupted sleep, hallucinations, depression and loss of balance.
Of the 29 symptoms listed, the participants were asked to rank such symptoms in the order in which they occurred relative to their disease flare-ups.
The study looked at not only the issues surrounding sleep, but also when the issues for participants began. (iStock)
The study found that three in five people experienced “vivid” and “distressing” nightmares that involved being trapped, attacked or falling — resulting in disrupted sleep.
One-third of those immune-compromised participants said they noticed the trend over a year before their lupus onset.
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Lupus is defined as “a disease that occurs when your body’s immune system attacks your own tissues and organs,” according to the Mayo Clinic.
One in four participants stated that they noticed hallucinations — although 85% said they didn’t experience the symptoms until the disease onset or later.
The study linked patients with an autoimmune disease, such as lupus, to disrupted sleep — including nightmares. (iStock)
Three in five people with lupus and one in three with other rheumatology-related conditions said they noticed an uptick in sleep disruptions just before their hallucinations would begin, according to SWNS.
The lead author of the study, Dr. Melanie Sloan of the University of Cambridge, noted in the study that in many cases, patients and doctors will not discuss mental health or neurological symptoms in relation to these diseases.
Three in five people with lupus noticed an uptick in sleep disruptions just before their hallucinations began.
“It’s important that clinicians talk to their patients about these types of symptoms and spend time writing down each patient’s individual progression of symptoms,” she said.
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Misdiagnosis was also mentioned in the study, as some participants said lupus and other autoimmune diseases were overlooked at first, SWNS reported.
For example, a participant from Scotland was diagnosed with borderline personality disorder at age 18 before being diagnosed with lupus at 19.
The study found that three in five people experienced disrupted sleep with “vivid” and “distressing” nightmares that involved being trapped, attacked or falling. (iStock)
“It was all very close together,” the participant said — noting that it was just a six-month period between “when my borderline personality disorder got under control and my lupus got under control,” SWNS said.
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Dr. Raj Dasgupta, a California-based chief medical adviser for Sleepopolis, was not involved in the study but shared reaction to the findings with Fox News Digital.
Dasgupta, who is quadruple-board certified in pulmonary, sleep, internal and critical care medicine, said the study supports the perspective that a “high prevalence of neuropsychiatric symptoms, such as headaches, mood and fatigue” are commonly linked to patients with systemic lupus erythematosus (SLE).
Dr. Raj Dasgupta said that sleep issues among patients with SLE need to be discussed in order for people to achieve a better quality of life. (Sleepoplis)
SLE is a “chronic disease that can affect any organ, including the nervous system,” Dasgupta noted.
“This study also supports the fact that patients with SLE are subject to complications of its treatment, including steroid-related psychosis,” he added.
Misdiagnosis was also mentioned in the study.
Sleep issues are common in people with SLE, said Dasgupta, with over half of patients experiencing restlessness, poor sleep quality and difficulty falling asleep.
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“These issues can be caused by pain, medication effects and the disease’s impact on the brain,” he said.
Fox News Digital reached out to the eClinicalMedicine journal for further information.
Sleepoplis consists of a team of writers, product reviewers and sleep experts who provide reviews and sleep health content, per the company’s website.
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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health.
In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.
The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.
In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)
The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.
Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.
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The scientists say this is the first direct evidence linking microplastics to prostate cancer.
“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)
The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.
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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.
“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”
“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.
Study limitations
Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.
“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.
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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”
About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.
The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)
For those concerned about microplastics, Sidransky offered some insights.
“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.
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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”
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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.
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There has been a shake-up in the Make America Healthy Again movement regarding glyphosate, a widely used herbicide that has been the subject of significant controversy.
The debate follows an executive order signed by President Donald Trump that ensures an adequate supply of elemental phosphorus and glyphosate-based herbicides related to national defense.
MAHA supporters have previously pushed a pesticide-free agenda, warning of potential health harms caused by glyphosate.
Dr. Marc Siegel, Fox News senior medical analyst, said he believes there is sufficient evidence linking glyphosate to neurodegenerative diseases, including ALS, Parkinson’s and multiple sclerosis, to warrant limiting exposure.
President Donald Trump signed an executive order that ensures an adequate supply of elemental phosphorus and glyphosate-based herbicides related to national defense. (AP Photo/Charlie Neibergall)
“With Parkinson’s, this association appears to be due to the gut, vagus nerve and brain axis, where the exposure affects the microbiome in the gut, which then ascends slowly up to the brain, causing the neurodegenerative disease years later,” Siegel told Fox News Digital.
“There is also a growing association being found between high-dose glyphosate or occupational exposure and metabolic disorders, liver disease and some cancers, specifically lymphoma.”
He added, “Growing research backs this. I favor limiting it.”
“When we apply them across millions of acres and allow them into our food system, we put Americans at risk.”
Studies have shown that glyphosate, which is used in products such as Roundup, owned by Monsanto, could raise cancer risk.
In one University of Washington study published in the journal Mutation Research, researchers found that exposure to it increased the risk of non-Hodgkin lymphoma by 41%.
The nonprofit Investigate Midwest, which analyzed data from both the U.S. Geological Survey and the National Cancer Institute, also recently found that pesticides may contribute to cancer rates.
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Among the top 500 counties for per-square-mile pesticide use, more than 60% had cancer rates above the national average of 460 cases per 100,000 people, according to the report.
Investigate Midwest, which is based in Illinois, interviewed more than 100 farmers, environmentalists, lawmakers and scientists as part of a partnership with the Pulitzer Center’s StoryReach U.S. Fellowship.
Among the top 500 counties for per-square-mile pesticide use, more than 60% had cancer rates above the national average of 460 cases per 100,000 people, according to one study. (iStock)
Iowa, which used 53 million pounds of pesticides last year, holds the nation’s title for second-highest cancer rate.
Bill Billings, a resident of Red Oak, Iowa, was diagnosed with cancer in 2014.
“The cancer specialist said, very directly, (my) cancer is a result of being exposed to chemicals,” Billings said in the report.
Kelly Ryerson, founder of Glyphosate Facts and owner of the Instagram account @glyphosategirl, told Fox News Digital her journey researching the herbicide began with her own health struggles.
Ryerson, who is based in California, previously struggled with chronic illness and autoimmune issues, which she said improved when she stopped eating gluten.
Iowa, which used 53 million pounds of pesticides last year, holds the nation’s title for second-highest cancer rate. (iStock)
After attending a medical conference at Columbia University’s Celiac Disease Center, Ryerson began to question modern farming practices rather than the gluten itself.
“A lot of times, farmers are spraying Roundup on our grains right before harvest to facilitate an easier harvest,” she said. “After that easier harvest, because everything’s dry at the same time, those crops go directly to the mill and may end up in our food supply, at alarmingly high levels.”
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In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization framework, classified glyphosate as “probably carcinogenic to humans.”
The classification was based on limited evidence of cancer in humans (notably non-Hodgkin lymphoma in some studies) and sufficient evidence in experimental animals.
“President Trump’s executive order reinforces the critical need for U.S. farmers to have access to essential, domestically produced crop protection tools, such as glyphosate,” a Monsanto spokesperson said. (Wolf von Dewitz/picture alliance via Getty Images)
A spokesperson for Monsanto told Fox News Digital it will comply with Trump’s order to produce glyphosate and elemental phosphorus.
“President Trump’s executive order reinforces the critical need for U.S. farmers to have access to essential, domestically produced crop protection tools, such as glyphosate,” the spokesperson said.
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HHS Secretary Robert F. Kennedy Jr. has long been a vocal critic of Roundup, working with his legal team in 2018 to award $289 million to a man who alleged the weed killer caused his non-Hodgkin lymphoma, according to reports.
Following backlash to Trump’s executive order, Kennedy said he supports the order but acknowledged that “pesticides and herbicides are toxic by design, engineered to kill living organisms.”
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“When we apply them across millions of acres and allow them into our food system, we put Americans at risk,” he posted on X. “Chemical manufacturers have paid tens of billions of dollars to settle cancer claims linked to their products, and many agricultural communities report elevated cancer rates and chronic disease.”
Fox News Digital reached out to the White House for comment.
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