Health
Disrupted sleep, plus nightmares could be linked to autoimmune diseases, experts say
Those who experience vivid nightmares and odd hallucinations might have an underlying autoimmune disease, a new study suggests.
An international research team led by scientists at the University of Cambridge and King’s College London explored the potential link between nightmares and hallucinations and systemic autoimmune rheumatic diseases.
The study, published in March in the journal eClinicalMedicine, included 676 people with lupus and 400 people from the medical field, as well as interviews with 69 people living with systemic autoimmune rheumatic diseases, SWNS reported.
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Those with autoimmune diseases were asked about the timing of their neurological and mental health symptoms, such as disrupted sleep, hallucinations, depression and loss of balance.
Of the 29 symptoms listed, the participants were asked to rank such symptoms in the order in which they occurred relative to their disease flare-ups.
The study looked at not only the issues surrounding sleep, but also when the issues for participants began. (iStock)
The study found that three in five people experienced “vivid” and “distressing” nightmares that involved being trapped, attacked or falling — resulting in disrupted sleep.
One-third of those immune-compromised participants said they noticed the trend over a year before their lupus onset.
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Lupus is defined as “a disease that occurs when your body’s immune system attacks your own tissues and organs,” according to the Mayo Clinic.
One in four participants stated that they noticed hallucinations — although 85% said they didn’t experience the symptoms until the disease onset or later.
The study linked patients with an autoimmune disease, such as lupus, to disrupted sleep — including nightmares. (iStock)
Three in five people with lupus and one in three with other rheumatology-related conditions said they noticed an uptick in sleep disruptions just before their hallucinations would begin, according to SWNS.
The lead author of the study, Dr. Melanie Sloan of the University of Cambridge, noted in the study that in many cases, patients and doctors will not discuss mental health or neurological symptoms in relation to these diseases.
Three in five people with lupus noticed an uptick in sleep disruptions just before their hallucinations began.
“It’s important that clinicians talk to their patients about these types of symptoms and spend time writing down each patient’s individual progression of symptoms,” she said.
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Misdiagnosis was also mentioned in the study, as some participants said lupus and other autoimmune diseases were overlooked at first, SWNS reported.
For example, a participant from Scotland was diagnosed with borderline personality disorder at age 18 before being diagnosed with lupus at 19.
The study found that three in five people experienced disrupted sleep with “vivid” and “distressing” nightmares that involved being trapped, attacked or falling. (iStock)
“It was all very close together,” the participant said — noting that it was just a six-month period between “when my borderline personality disorder got under control and my lupus got under control,” SWNS said.
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Dr. Raj Dasgupta, a California-based chief medical adviser for Sleepopolis, was not involved in the study but shared reaction to the findings with Fox News Digital.
Dasgupta, who is quadruple-board certified in pulmonary, sleep, internal and critical care medicine, said the study supports the perspective that a “high prevalence of neuropsychiatric symptoms, such as headaches, mood and fatigue” are commonly linked to patients with systemic lupus erythematosus (SLE).
Dr. Raj Dasgupta said that sleep issues among patients with SLE need to be discussed in order for people to achieve a better quality of life. (Sleepoplis)
SLE is a “chronic disease that can affect any organ, including the nervous system,” Dasgupta noted.
“This study also supports the fact that patients with SLE are subject to complications of its treatment, including steroid-related psychosis,” he added.
Misdiagnosis was also mentioned in the study.
Sleep issues are common in people with SLE, said Dasgupta, with over half of patients experiencing restlessness, poor sleep quality and difficulty falling asleep.
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“These issues can be caused by pain, medication effects and the disease’s impact on the brain,” he said.
Fox News Digital reached out to the eClinicalMedicine journal for further information.
Sleepoplis consists of a team of writers, product reviewers and sleep experts who provide reviews and sleep health content, per the company’s website.
For more Health articles, visit foxnews.com/health
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Health
West Nile virus detected in southern state as health officials warn residents about mosquitoes
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Health officials in Nashville are urging residents to protect themselves from mosquito bites after West Nile virus was detected in mosquitoes for the first time this year.
The Metro Public Health Department (MPHD) announced the virus was found in a mosquito pool collected near Cass Street in North Nashville, marking the city’s first detection of West Nile virus in 2026 and the earliest positive mosquito sample of the season.
The detection comes after health officials reported elevated West Nile virus activity in mosquito pools during 2025, when one human case of the virus was confirmed.
“We can all play a role in reducing the presence of mosquitoes in our community, making our outdoor areas both more pleasant and safer from mosquito-borne diseases like West Nile virus,” Dr. Sanmi Areola, director of health at the Metro Public Health Department, said in a statement to Fox 17.
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A close-up shows mosquitoes feeding in Tehatta, India, on May 1, 2026. Health officials in Nashville recently detected West Nile virus in a mosquito pool, prompting residents to take precautions against mosquito bites. (Soumyabrata Roy/NurPhoto via Getty Images)
“As our team educates those in the area where West Nile virus was found, we hope the rest of our community does what they can to protect themselves and their families from mosquitoes this summer.”
According to the Centers for Disease Control and Prevention, West Nile virus is the leading mosquito-borne disease in the United States. Most people infected with the virus do not develop symptoms, but about one in five experience fever, headaches, body aches, vomiting, diarrhea or a rash. Fewer than 1% develop a serious neurological illness that can affect the brain or spinal cord, with older adults and people with weakened immune systems facing the greatest risk.
Public health officials routinely trap and test mosquitoes throughout the summer to monitor for West Nile virus activity. A positive mosquito sample does not necessarily mean people in the area will become infected, but it serves as an early warning that the virus is circulating locally.
In response to the positive test, MPHD said crews are distributing educational flyers in the affected neighborhood, increasing mosquito trapping, monitoring standing water and applying larvicide where needed to help reduce mosquito populations. The department said it does not spray insecticide to kill adult mosquitoes.
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The Aedes mosquito is a known vector for several viruses, including West Nile virus, yellow fever virus, dengue virus, chikungunya virus, and Zika virus. (Soumyabrata Roy/NurPhoto via Getty Images)
Residents can also request a free backyard inspection from the department’s Pest Management team to identify areas where mosquitoes may be breeding.
Health officials recommend eliminating standing water from bird baths, flowerpots, buckets, old tires, children’s toys and other outdoor containers where mosquitoes lay eggs. Trimming overgrown vegetation around homes can also help reduce mosquito activity.
A field sample of mosquitoes that could carry West Nile Virus is seen at offices of the Riverside County Department of Environmental Health on April 26, 2007, in Hemet, California. (David McNew/Getty Images)
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To help prevent mosquito bites, the health department recommends using EPA-approved insect repellents containing DEET, picaridin or oil of lemon eucalyptus, wearing long sleeves and pants outdoors during peak mosquito hours around dusk and dawn, and making sure window and door screens are in good repair.
Officials said reducing mosquito breeding around homes can help lower the risk of West Nile virus and other mosquito-borne illnesses throughout the community.
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Before the first successful vaccine was developed in 1796, Americans had little protection against deadly infectious diseases like smallpox, measles and diphtheria.
Over the next 250 years, vaccines helped eliminate or dramatically reduce many vaccine-preventable infectious diseases, preventing millions of illnesses, infections and deaths.
“There is a reason that vaccines are widely considered to be the greatest public health tool after sanitation,” Fox News senior medical analyst Dr. Marc Siegel told Fox News Digital.
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“They are designed to ‘fool’ the immune system into thinking it has seen a disease, creating an ‘immune memory’ to provoke an immune response to the pathogen when it actually does appear.”
“True vaccines have side effects, and there is the risk of vaccine injury — but overall, the benefit to the individual and society vastly outweighs any harm,” Siegel added.
Over 250 years, vaccines helped eliminate or dramatically reduce many vaccine-preventable infectious diseases, preventing millions of illnesses, infections and deaths. (iStock)
As the U.S. marks its 250th anniversary, the following vaccines stand out among the most significant medical achievements in the country’s history.
No. 1: Smallpox
Smallpox, a highly contagious viral disease caused by the variola virus, was one of the world’s deadliest diseases before vaccination, killing about 30% of those infected, according to CDC data.
The infectious disease had no cure and spread through close person-to-person contact, causing fever, fatigue and a distinctive rash that led to pus-filled blisters. Survivors were often left with permanent scarring or blindness.
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The first successful vaccine, developed by English physician Edward Jenner in 1796, eventually transformed public health in the United States.
Jenner’s smallpox vaccine ultimately led to the global eradication of smallpox, according to the World Health Organization. The vaccine is no longer given routinely to the public and is mainly used for select military, laboratory and emergency-response needs.
“There is a reason that vaccines are widely considered to be the greatest public health tool after sanitation.”
“The first vaccine against smallpox eradicated a disease that killed 5-10% of all humans who had ever lived for almost all of human history,” Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, told Fox News Digital. “Then the drumbeat began of relentless progress right at the eve of the 20th century.”
No. 2: Rabies
A viral disease that attacks the brain and nervous system, rabies spreads through the saliva of infected mammals, most commonly through the bites of dogs, bats, raccoons, skunks and foxes.
Once symptoms begin, rabies is almost always fatal, according to the National Institutes of Health (NIH).
Rabies is a viral disease that attacks the brain and nervous system and spreads through the saliva of infected mammals, most commonly through the bites of dogs, bats, raccoons, skunks and foxes. (iStock)
Although there is no cure, vaccination immediately after exposure can prevent the disease. It can also be given before exposure for people at high risk.
Researcher Louis Pasteur created the first rabies vaccine in 1885, according to The Children’s Hospital of Philadelphia (CHOP). Today, prompt vaccination after exposure remains the standard way to prevent an otherwise almost universally fatal disease.
No. 3: Diphtheria
Diphtheria is a bacterial infection that can cause a thick coating in the throat. It was fatal for some, and survivors could face serious complications, including heart damage, paralysis and breathing problems, according to the CDC.
Before the vaccine’s introduction in the 1920s, diphtheria was one of the leading causes of illness and death among youth in the U.S. During that decade, there were 100,000 to 200,000 cases and 13,000 to 15,000 deaths recorded each year, mostly affecting children.
Before the vaccine’s introduction in the 1920s, diphtheria was one of the leading causes of illness and death among youth in the U.S. (Ebrahim Hamid/AFP via Getty Images)
The diphtheria toxoid vaccine was introduced in the 1920s. Diphtheria is now extremely rare in the U.S. due to widespread vaccinations, per the CDC.
The vaccine remains part of the routine childhood immunization schedule as part of the DTaP series, with boosters recommended for teens, adults and pregnant women.
No. 4: Tetanus
Tetanus is a bacterial disease caused by Clostridium tetani, which enters the body through cuts or wounds, according to the CDC. The infection can cause severe muscle spasms, “lockjaw” and death.
Before vaccination, tetanus was often fatal because severe muscle spasms could make it impossible to swallow or breathe. Although the disease is not spread from person to person, hundreds of Americans died from tetanus each year, records show.
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The tetanus toxoid vaccine was developed in the 1920s, according to CHOP. Tetanus vaccination remains part of the routine childhood immunization schedule, with boosters recommended every 10 years and as needed following certain wounds.
No. 5: Pertussis (whooping cough)
Whooping cough (pertussis) is a highly contagious bacterial infection that causes severe coughing fits, often making it difficult to breathe, eat or sleep. Infants are at highest risk, as they can develop pneumonia, seizures, brain damage or even death.
Before widespread vaccination, the U.S. recorded more than 200,000 pertussis cases and thousands of youth hospitalizations each year, the CDC states.
Whooping cough is a highly contagious bacterial infection that causes severe coughing fits, often making it difficult to breathe, eat or sleep. (iStock)
The first pertussis vaccine was introduced in the 1910s, followed by the combination DTP (diphtheria, tetanus and pertussis) vaccine in the 1940s.
After widespread vaccination, cases fell by more than 90% and deaths from the disease became uncommon. The pertussis vaccine remains part of the routine U.S. immunization schedule for children, teens and adults, and doctors recommend vaccination during pregnancy to pass protective antibodies to newborns.
No. 6: Influenza
This contagious viral respiratory illness can cause serious complications, hospitalization and death, CDC data shows.
Before the vaccine was available, seasonal flu epidemics caused widespread illness and death every year. During the 1918 influenza pandemic (“Spanish flu”), an estimated one-third of the world’s population was infected and at least 50 million people died worldwide, including about 675,000 Americans.
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The first U.S. flu vaccine was licensed in 1945, helping launch routine seasonal influenza vaccination programs.
Widespread vaccination has significantly reduced the risk of flu illness, hospitalization and death. The CDC recommends that everyone 6 months and older receives a seasonal flu vaccine each year, with rare exceptions. The vaccine is updated annually to target changing strains.
No. 7: Polio
Polio (poliomyelitis), a highly contagious viral disease caused by poliovirus, spreads mainly through contact with contaminated food, water or stool, per the CDC.
For some, the virus can attack the nervous system, causing permanent paralysis, breathing difficulties and death. During the early 1950s, more than 15,000 cases of paralytic polio were reported each year in the U.S.
A pediatrician vaccinates a child with a 6-way combination vaccine against diphtheria, tetanus (tetanus), polio, pertussis, Haemophilus influenzae type b (Hib) and hepatitis B. (Julian Stratenschulte/dpa (Julian Stratenschulte/picture alliance via Getty Images))
In 1955, Jonas Salk’s polio vaccine was introduced in the country, greatly reducing case counts. In 1979, the U.S. was declared free of wild poliovirus, according to the World Health Organization.
Injected polio vaccination is still part of the routine childhood U.S. immunization schedule.
No. 8: MMR (measles, mumps, rubella)
Before vaccines, measles, mumps and rubella were common childhood diseases that infected millions of Americans and could cause serious complications.
Prior to the measles vaccine, nearly all American children contracted the highly contagious viral disease by age 15, according to the NIH. About 400 to 500 Americans died of measles each year, while about 1,000 experienced brain swelling and 48,000 were hospitalized, records show.
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Before the first mumps vaccine, about 186,000 cases were reported in the U.S. each year, and the disease was a common cause of children’s meningitis, per the NIH.
Rubella epidemics also regularly occurred in the U.S. before vaccination. Between 1964 and 1965, about 12.5 million Americans were infected, resulting in approximately 2,100 newborn deaths and 20,000 babies born with congenital rubella syndrome, causing blindness, deafness, heart defects and developmental disabilities.
A doctor is shown giving a vaccine to a baby. Rubella epidemics regularly occurred in the U.S. before vaccination (iStock)
The measles vaccine was introduced in 1963, followed by mumps in 1967 and rubella in 1969. In 1971, the MMR (measles, mumps and rubella) vaccine became available, protecting against all three contagious viral diseases in a single shot. Prior to the combined vaccine, children typically had to receive three separate shots, the CDC noted.
Widespread vaccination has reduced cases of all three diseases by more than 99% in the United States, per NIH data.
Measles was declared eliminated in the U.S. in 2000, meaning it was no longer spreading continuously within the country. Routine vaccination also led to endemic rubella being declared eliminated in the U.S. in 2004.
No. 9: Hepatitis B
Hepatitis B, a viral infection that attacks the liver, is spread through contact with infected blood and other body fluids, according to the CDC.
Some people develop chronic hepatitis B, which can lead to cirrhosis, liver failure and liver cancer.
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Before vaccination, hepatitis B was a major public health threat in the U.S. In the early 1980s, an estimated 200,000 to 300,000 Americans contracted the infection each year, the NIH states. Infants infected at birth were at particularly high risk, with about 90% developing chronic infection.
The hepatitis B vaccine was licensed in 1981, and the CDC began recommending universal infant vaccination in 1991. Since then, acute hepatitis B cases have declined by more than 80% in the U.S., and infections among children and adolescents have fallen by more than 95%, per the NIH.
No. 10: Hib
Haemophilus influenzae type b (Hib) is a bacterial infection that can cause pneumonia, meningitis, bloodstream infections and severe throat swelling, per the CDC.
Severe cases can lead to hearing loss or brain damage.
Hib was once the leading cause of bacterial meningitis in young children in the U.S., with around 20,000 serious infections and 1,000 deaths reported each year in those 5 and younger. (iStock)
Hib was once the leading cause of bacterial meningitis in young children in the U.S., with around 20,000 serious infections and 1,000 deaths reported each year in those 5 and younger.
The first Hib vaccine was licensed in 1985, with routine immunizations reducing invasive disease by more than 99%, according to CDC data. The infection is now rare in the U.S.
No. 11: Chickenpox/varicella
Chickenpox (varicella) is a highly contagious viral disease caused by the varicella-zoster virus that causes an itchy, blister-like rash, fever and fatigue, according to the CDC.
In some people, it can lead to serious complications, including pneumonia, brain inflammation and bacterial skin infections.
“There is a reason that vaccines are widely considered to be the greatest public health tool after sanitation.”
Before the first chickenpox vaccine became available in the U.S. in 1995, about four million Americans were infected each year, with around 100 to 150 deaths and up to 13,000 hospitalizations, according to the CDC and NIH.
Since routine two-dose childhood vaccination began, hospitalizations and deaths have declined by more than 90%, and severe complications have become rare, CDC data shows.
No. 12: Hepatitis A
A highly contagious viral liver infection, hepatitis A spreads mainly through contaminated food or water or close contact with an infected person, per the CDC.
While it does not cause chronic liver disease like hepatitis B, it can cause weeks or months of illness and, in rare cases, liver failure.
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Before vaccination, outbreaks led to as many as 30,000 infections each year.
The first hepatitis A vaccine was licensed in the U.S. in 1995. Since routine childhood vaccination began, infection rates have dropped by more than 95%, according to the NIH.
No. 13: Pneumococcal
Pneumococcal disease, caused by the bacterium Streptococcus pneumoniae, can lead to pneumonia, meningitis, bloodstream infections, ear infections and sinus infections, the CDC states.
Before vaccination, pneumococcal disease caused thousands of cases of meningitis and bloodstream infections and hundreds of deaths among young children. (iStock)
Before vaccination, pneumococcal disease caused thousands of cases of meningitis and bloodstream infections and hundreds of deaths among young children, per the NIH. Older adults also faced a high risk of hospitalization from bacterial pneumonia.
The first pneumococcal conjugate vaccine was licensed in 2000. Routine childhood vaccination has dramatically reduced disease rates, and newer vaccines have been developed to protect against emerging bacterial strains.
No. 14: HPV
The most common sexually transmitted infection in the U.S., the human papillomavirus (HPV) can cause cervical, anal, penile, vaginal, vulvar and oropharyngeal cancers, according to the CDC.
The HPV vaccine was licensed in 2006, becoming the first immunization designed to prevent multiple types of cancer.
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Since the vaccine became available, HPV infections, precancers and genital warts have declined significantly, CDC data shows.
HPV vaccination is now part of the routine U.S. immunization schedule, with two doses recommended for those younger than 15 and three doses for those 15 and older.
No. 15: Rotavirus
Rotavirus is a highly contagious virus that primarily affects infants and young children, causing severe diarrhea, vomiting and fever.
Before the vaccine became available in 2006, nearly every child contracted the virus by age 5, often leading to severe dehydrating diarrhea, the CDC states. Up to 70,000 children were hospitalized and 20 to 60 died each year in the U.S.
Before the shingles vaccine was available, about one million Americans developed the infection each year, with adults over 50 at highest risk. (iStock)
Since routine rotavirus vaccination began, hospitalizations, emergency room visits and severe illness have declined significantly. Infants receive two or three oral doses as part of the routine immunization schedule.
No. 16: Shingles
Shingles is a painful rash caused by reactivation of the varicella-zoster virus, the same one that causes chickenpox, per the CDC. It can cause severe nerve pain lasting months or even years.
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Before the vaccine was available, about one million Americans developed shingles each year, with adults over age 50 at highest risk.
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The first shingles vaccine was licensed in 2006, and the more effective Shingrix vaccine was introduced in 2017, greatly reducing the risk of shingles and long-term nerve pain, according to the CDC and FDA.
Experts recommend two doses for adults 50 and older and for certain immunocompromised adults ages 19 and older.
No. 17: COVID-19
When the COVID-19 pandemic spread worldwide in 2020, there was no vaccine to prevent severe illness from the infection, which is caused by the SARS-CoV-2 virus.
The Food and Drug Administration on June 16, 2023, told COVID-19 vaccine makers to update fall shots to target the latest omicron strain. (AP Photo/Steve Helber, File)
In the U.S., the contagious virus caused millions of hospitalizations and more than 1.2 million deaths, according to data from the CDC and NIH.
The first COVID-19 vaccines received emergency authorization in December 2020. Multiple studies have shown that the vaccines significantly reduce the risk of severe illness, hospitalization and death, particularly among high-risk groups.
“COVID vaccines saved millions of lives around the world during the COVID pandemic.”
“COVID vaccines saved millions of lives around the world during the COVID pandemic,” Siegel said.
Although the CDC continues to recommend COVID-19 vaccination, specific guidance varies by age, risk level and previous vaccination history.
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Glanville, whose company is currently working to develop a universal flu vaccine, among others, summed up the impact of these and other vaccines in America.
People should contact a doctor to discuss individual recommendations for vaccines, which can vary by age, health status, medical history and risk factors. (iStock)
“To truly understand the impact that vaccines have had in the last 100 years, read through the list of pathogens along the timeline until they become familiar to you, until they include things you or your family may have been infected by in your own life,” he advised. “You may barely even recognize most of the pathogens in the first half of the list – because vaccines pushed them out of the human experience. That is the power of vaccines.”
People should contact a doctor to discuss individual recommendations for vaccines, which can vary by age, health status, medical history and risk factors.
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