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First look: San Francisco 49ers at Chicago Bears odds and lines

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The San Francisco 49ers and the Chicago Bears meet in Week 1 motion with kickoff from Soldier Area on Sunday, Sept. 11, set for 1 p.m. ET (FOX). Under, we analyze Tipico Sportsbook‘s strains across the 49ers vs. Bears odds and contours; examine again for our NFL picks and predictions.

A brand new period is about to formally start for the visiting 49ers as final 12 months’s Third-overall draft choose, Trey Lance, is about to take over at quarterback. San Francisco enters the season with lofty expectations and with the 2nd-best odds to win the NFC West behind solely the defending champion Los Angeles Rams.

San Francisco completed the preseason 2-1 after falling 17-0 on the Houston Texans of their ultimate look. Lance led 3 scoreless drives.

Additionally see: All Week 1 odds and contours

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Chicago opens up on absolutely the reverse finish of the spectrum. The Bears have the worst odds to win the division within the NFC North and are amongst the longest odds within the league to win the Tremendous Bowl. QB Justin Fields enters his 2nd season with what seems to be a weak supporting solid and can have an uphill battle to guide this group to many victories.

The Bears wrapped up a 3-0 preseason with a 21-20 squeaker on the Cleveland Browns. Fields notched 3 first-half TDs and completed 14-of-16 for 156 yards.

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49ers at Bears odds, unfold and contours

Odds supplied by Tipico Sportsbook; entry USA TODAY Sports activities Scores and Sports activities Betting Odds hub for a full listing. Strains final up to date Sunday, Aug. 28, at 7:01  p.m. ET.

Cash line (ML): 49ers -350 (wager $350 to win $100) | Bears +265 (wager $100 to win $265)
Towards the unfold (ATS): 49ers -7.5 (+102) | Bears +7.5 (-125)
Over/Below (O/U): 41.5 (O: -110 | U: -110)

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2022 betting stats: (2021 stats together with postseason)

ML: 49ers 12-8 | Bears 6-11
ATS: 49ers 12-8 | Bears 6-11
O/U: 49ers 8-12 | Bears 7-10

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49ers vs. Bears head-to-head

The 49ers lead the all-time sequence 35-32-1, together with 3-0 in postseason play.

The 49ers have gained 5 of the final 9 conferences vs. the Bears since 2006 — each straight-up and ATS. The Over has hit in 5 of 9 conferences, too.

The squads have met as soon as with both QB underneath heart, a 33-22 San Francisco highway win and canopy in Week 8 with Fields beginning for the Bears. Nonetheless, QB Jimmy Garoppolo performed for the 49ers in that assembly.

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