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Arizona Cardinals at Buffalo Bills: Predictions, picks and odds for NFL Week 1 game

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Arizona Cardinals at Buffalo Bills: Predictions, picks and odds for NFL Week 1 game


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The Buffalo Bills have won four straight AFC East titles, but their streak could be in jeopardy in 2024. The departure of star receiver Stefon Diggs opens up the possibility for regression from quarterback Josh Allen. Couple that with the fact that the team’s No. 2 receiver Gabe Davis also split town, and there is plenty reason to feel uneasy about this team’s offensive capabilities this season.

At the very least, the Bills return standout tight end Dalton Kincaid as well as late-season breakout receiver Khalil Shakir. The team also added second-round receiver Keon Coleman to the fold as well. If James Cook can continue holding down their backfield, the Bills could still boast one of the most effective offenses in the league.

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Their opponent this week will be the Arizona Cardinals, who have a lot to look forward to on offense. Kyler Murray, Trey McBride, James Conner, and Marvin Harrison Jr. should be spectacular but the team’s defense lacks the same high-end potential. While this team could have the offensive firepower to surprise some people, it would take a massive improvement on the other side of the ball for them to compete for a Super Bowl.

PROP TALK: These are the best prop bets for NFL games this week 

Cardinals vs. Bills odds, moneyline, over/under

The Bills are favorites to defeat the Cardinals, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: Bills (-6.5)
  • Moneyline: Bills (-300); Cardinals (+240)
  • Over/under: 48

Not interested in this game? Our guide toNFL betting odds, picks and spreads has you covered with Thursday Night Football odds and Monday Night Football odds.

New to sports betting? USA TODAY readers can claim exclusive promos and bonus codes with the best online sportsbooks and sports betting sites.

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FEELING LUCKY? Here are the best parlay bets and odds for NFL games this week 

NFL Week 1 odds, predictions and picks

Ravens vs. Chiefs | Packers vs. Eagles | Jaguars vs. Dolphins | Steelers vs. Falcons | Vikings vs. Giants | Panthers vs. Saints | Patriots vs. Bengals | Titans vs. Bears | Cardinals vs. Bills | Texans vs. Colts | Raiders vs. Chargers | Broncos vs. Seahawks | Commanders vs. Buccaneers | Cowboys vs. Browns | Rams vs. Lions | Jets vs. 49ers

Lorenzo Reyes: Bills 25, Cardinals 23

I think Buffalo may struggle a bit on offense this season. Josh Allen may feel the pressure of needing to create more, given the loss of Stefon Diggs, and this could prompt carelessness with the ball. That has long been a problem for Buffalo, which should still win this game. Still, I think it’s a closer affair with the Cardinals’ improved roster.

Tyler Dragon: Bills 27, Cardinals 20

Not much is expected of Kyler Murray and the Cardinals this season. Cardinals rookie wideout Marvin Harrison Jr. is a player to watch. Arizona will play teams tough, but they lack talent across the board. The Bills lost plenty of veteran leaders over the offseason, Stefon Diggs. Josh Allen is going to have to elevate Buffalo’s offense the way franchise quarterbacks are expected.

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Safid Deen: Bills 26, Cardinals 16

Josh Allen has some new teammates to get used to, but he’s still one of the best offensive players in the sport. He’ll be able to gut out a win against Kyler Murray and Arizona.

Richard Morin: Bills 23, Cardinals 15

A still-getting-to-know-you Bills offense combined with a sleepy Cardinals team playing on the East Coast is a recipe for a slow game. I think the Bills get it done, but it will produce questions of whether they have the offense to be a legitimate AFC contender in 2024.

MOST VALUABLE BET: Who is the favorite to win NFL MVP in 2024? 



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Arizona Diamondbacks News, 5/25: Memorial Day

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Arizona Diamondbacks News, 5/25: Memorial Day


Recaps [Arizona Sports] Diamondbacks do not mess around with Rockies to close 6-1 homestand – The Arizona Diamondbacks smacked seven extra-base hits, none of which left the yard, in an all-around dominant win over the Colorado Rockies on Sunday, 9-1. Ryne Nelson threw a career-high eight innings with one earned run, while the offense supplied […]



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Kavan’s shutout lifts Texas to win over Arizona State, back to WCWS

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Kavan’s shutout lifts Texas to win over Arizona State, back to WCWS


AUSTIN (KXAN) — Texas will return to the Women’s College World Series to defend its national title.

The Longhorns capped a 2-1 series win in the super regional round over Arizona State with a 5-0 victory Sunday at McCombs Field. Katie Stewart drove in four runs, and Teagan Kavan hurled a complete-game shutout with five strikeouts.

AUSTIN, TX – APRIL 12: Texas Longhorns utility Katie Stewart (20) gets a hit during the SEC college softball game between Texas Longhorns and Oklahoma Sooners on April 12, 2026, at Red & Charline McCombs Field in Austin, Texas. (Photo by Adam Davis/Icon Sportswire via Getty Images)

Austin Super Regional: No. 2 Texas 2, Arizona State 1

The win sends the second-seeded Longhorns back to Devon Park in Oklahoma City, where they claimed the program’s first national championship last season. They’ll face Tennessee at 1:30 p.m. CT Thursday in the double-elimination tournament.

It’s the ninth time the Longhorns have been to the WCWS.

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Texas bounced back from a 4-1 loss to open the best-of-3 series on Friday against the Sun Devils, claiming Saturday’s game 4-3 thanks to a pinch-hit 2-run home run in the seventh inning by Victoria Hunter.

Stewart provided the bulk of the offensive punch for the Longhorns, smacking a pair of 2-run singles in the third and sixth innings. Shortstop Vivi Martinez capped a 15-pitch at-bat against Sun Devils pitcher Kenzie Brown with an RBI triple in the fifth to score Kayden Henry. Martinez fouled off 11 pitches during the plate appearance, and then ripped a pitch down the first-base line that rolled all the way to the right-field wall, plating Henry to give Texas a 3-0 lead.

Martinez said she kept telling herself to win each pitch.

“I was just trying to keep it simple,” she said. “She has a great changeup, so I had to be aware of that.”

Kavan kept the Sun Devils off balance, forcing eight groundouts and eight flyouts to go with her strikeouts. She scattered five hits, allowing a 2-out triple to Yannixa Acuna in the fourth on a pop-up that dropped in shallow right field just out of Leighann Goode’s diving catch attempt. With the outfield heavily shifted the opposite way, the ball squirted into foul territory, allowing the speedy Acuna to scamper to third.

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After Kavan walked Brooklyn Ulrich, she got Tiare Ho-Ching to ground out to end the inning, escaping the jam unscathed.

“Teagan was lights out. She showed the mindset of a warrior,” Longhorns head coach Mike White said. “The ability to put things that don’t go her way aside, and come out and compete for her team. She loves her team.”

Texas (47-11) was 7-for-19 with runners on and 3-for-9 with runners in scoring position. Arizona State didn’t have a hit with runners in scoring position, going 0-for-5. Both of Stewart’s 2-run singles came with two outs.

Stewart, Henry and Martinez all had two hits for the Longhorns. Acuna had two hits for the Sun Devils.

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Arizona wins 4th consecutive Territorial Cup Series

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Arizona wins 4th consecutive Territorial Cup Series


Arizona is on a tear against its in-state rival. For a fourth straight season, the Wildcats won the Territorial Cup Series over ASU, dominating the 22 common varsity sports the two schools compete in. Arizona won this year’s series by a margin of 13.5 to 8.5. Since 2009, Arizona has won the Territorial Cup Series […]



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