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Scientists say they ‘de-extincted’ dire wolves. Experts at La Brea Tar Pits are skeptical

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Scientists say they ‘de-extincted’ dire wolves. Experts at La Brea Tar Pits are skeptical

When news broke that scientists in Texas had succesfully reintroduced the long-extinct dire wolf to the modern world, more people than just “Game of Thrones” fans took notice.

Researchers at the Natural History Museum’s La Brea Tar Pits, where a wall is decorated with hundreds of dire wolf skulls, had questions.

Namely, are they really dire wolves? Turns out, it depends on how you define it.

“What they have created is basically a genetically engineered gray wolf that has been given genetic traits so they can express morphological or physical traits that more resemble dire wolves,” said Kayce Bell, a terrestrial mammal curator at the Natural History Museum. “The technology and the tools that they are developing with this work are incredible and very powerful, but the terms that are being used to discuss it, I think, are misleading.”

Earlier this week, biotechnology company Colossal Biosciences in Dallas announced they had “de-extincted” the dire wolf, sharing the news of the births of three healthy pups. Over 18 months, experts there extracted and sequenced ancient DNA from two dire wolf fossils — a 13,000-year-old tooth from Sheridan Pit, Ohio, and a 72,000-year-old inner ear bone from American Falls, Idaho. With that ancient DNA, scientists identified gene variants specific to dire wolves and then performed multiplex gene editing with a genome from the gray wolf, dire wolves’ closest living relatives. They used domestic dogs as surrogate mothers to birth the three pups.

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This undated photo provided by Colossal Biosciences shows two pups that were genetically engineered with similarities to the extinct dire wolf.

(Colossal Biosciences via Associated Press)

Colossal’s chief science officer, Beth Shapiro, said she understands the scientific skepticism that came with the announcement.

“I get it,” she said. “It’s frustrating when you work in paleontology and you feel like it’s not effective science communication, and I wish I’d done a bit better.”

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Though Southern California has a jackpot of dire wolf fossils relative to other sites, extracting DNA from the local samples is difficult. Shapiro said she’s been trying and unable to collect DNA from local samples for 20 years. Among the reasons it’s challenging to collect, experts say, is that L.A.’s urban landscape bakes in the sun, heating up the asphalt, which could degrade ancient DNA buried underneath.

La Brea Tar Pits has the highest concentration of dire wolf fossils in the world, with remains from over 4,000 dire wolves found at the site. They lived in the region for at least 50,000 years, disappearing about 13,000 years ago.

“There’s no other site on Earth that even comes close to that,” said Emily Lindsey, the associate curator and excavation site director at La Brea Tar Pits.

Dire wolves, native to Southern California but not limited to the region, were highly adaptable and had a very wide range of environmental tolerances before the species went extinct about 10,000 years ago, Lindsey said.

The three pups — Romulus and Remus, who were born in October, and Khaleesi, born in January — now live on an ecological preserve at an undisclosed location that spans over 2,000 acres and hosts 10 full-time staff members who care for and observe them. The preserve is certified by the American Humane Society and registered with the U.S. Department of Agriculture.

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Depending on how you look at it, that could be dire wolf territory now.

In 2016, the International Union for Conservation of Nature published a report that focused on de-extinction and defined it as “bringing back a proxy of an extinct species that resembles it in some way, phenotypically, physiologically, ecologically,” Shapiro said.

But in the end, she said she’s not really hung up on what the animals are called beyond their names, inspired by founders of Rome and the “Game of Thrones” show.

“Call it a de-extinct dire wolf that abides by the definition that the scientific community agreed on 10 years ago. Call it Colossal’s dire wolf. Call it a gray wolf with 20 edits that looks and acts like a dire wolf and is a functional replacement for a dire wolf,” Shapiro said.

Part of Colossal’s announcement this week included news that they had also successfully created four clones of the endangered red wolf using a new noninvasive cloning technology. Both Lindsey and Bell said they appreciated Colossal’s work on conserving endangered species, but think that focusing on conservation is a more productive use of resources.

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“There are potentially useful applications of some of these technologies, particularly for preventing highly endangered species from going extinct. I think that would be a far more efficient application of these technologies than trying to bring something resembling an extinct species back to life,” Lindsey said. “I’d hate to have to be trying to de-extinct wolves once they go extinct, right?”

Colossal’s Chief Executive Ben Lamm said the company wants to pair their “de-extinction events” with work they’re doing to protect critically endangered species. The company’s other de-extinction hopes include reviving the woolly mammoth, the dodo, and the thylacine, or Tasmanian tiger. To Lamm and Shapiro, de-extinction and conservation can work in tandem.

“Conservation and de-extinction are not at odds with each other. The de-extinction toolkit should be part of the increasing number of ways that we have at our fingertips to be able to help endangered species survive,” Shapiro said.

Lamm, who held up drawings of dodos and other extinct animals children had sent to the Colossal team during a Zoom interview with The Times, said he thinks the milestone could also inspire more people to pursue careers in related fields.

“The world needs a little hope right now, and I think the world needs more science. Hopefully, we’re providing a little bit of both,” he said.

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And yes, of course “Jurassic Park” quotes and references are tossed Lamm and Shapiro’s way with stunning frequency.

“People actually say to us, ‘Don’t you know what happened in Jurassic Park?,’ equating it to, like, Chernobyl,” Lamm said. “ ‘Didn’t you see what happened there?’ Not, ‘Didn’t you watch the movie and learn anything about human hubris from the movie?’ They don’t say that.”

Shapiro added: “People are yelling at us that these aren’t real dire wolves. But no one has ever questioned whether the dinosaurs in ‘Jurassic Park’ are real dinosaurs.”

While the debate is still open, Lindsey said she invites anyone curious about the creatures to visit La Brea Tar Pits to see some of the “real dire wolves” that they have excavated at the site.

“It’s a really cool opportunity — one that you don’t get in almost any other city in the world — to come and really see the incredible diversity of large animals that lived here until very recently,” Lindsey said.

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A push to end a fractured approach to post-fire contamination removal

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A push to end a fractured approach to post-fire contamination removal

The patchwork efforts to identify and safely remove contamination left by the 2025 Eaton and Palisades fires has been akin to the Wild West.

Experts have given conflicting guidance on best practices. Shortly after the fires, the federal government suddenly refused to adhere to California’s decades-old post-fire soil-testing policy; California later considered following suit.

Meanwhile, insurance companies have resisted remediation practices widely recommended by scientists for still-standing homes.

A new bill introduced this week by state Assemblymember John Harabedian (D-Pasadena) aims to change that by creating statewide science-based standards for the testing and removal of contamination deposited by wildfires — specifically within still-standing homes, workplaces and schools, and in the soil around those structures.

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“In a state where we’ve had a number of different wildfires that have happened in urban and suburban areas, I was shocked that we didn’t have a black-and-white standard and protocol that would lay out a uniform post-fire safety standard for when a home is habitable again,” Harabedian said.

The bill, AB 1642, would task the state’s Department of Toxic Substances Control with creating standards by July 1, 2027. The standards would only serve as guidance — not requirements — but even that would be helpful, advocates say.

“Guidance, advisories — those are extremely helpful for families that are trying to return home safely,” said Nicole Maccalla, who leads data science efforts with Eaton Fire Residents United, a grassroots organization addressing contamination in still-standing homes. “Right now, there’s nothing … which means that insurance companies are the decision-makers. And they don’t necessarily prioritize human health. They’re running a business.”

Maccalla supports tasking DTSC with determining what levels of contamination pose an unacceptable health risk, though she does want the state to convene independent experts including physicians, exposure scientists and remediation professionals to address the best testing procedures and cleanup techniques.

Harabedian said the details are still being worked out.

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“What’s clear from my standpoint, is, let’s let the public health experts and the science and the scientists actually dictate what the proper standards and protocol is,” Harabedian said. “Not bureaucrats and definitely not insurance companies.”

For many residents with still-standing homes that were blanketed in toxic soot and ash, clear guidance on how to restore their homes to safe conditions would be a much welcome relief.

Insurance companies, environmental health academics, and professionals focused on addressing indoor environmental hazards have all disagreed on the necessary steps to restore homes, creating confusion for survivors.

Insurance companies and survivors have routinely fought over who is responsible for the costs of contamination testing. Residents have also said their insurers have pushed back on paying for the replacement of assets like mattresses that can absorb contamination, and any restoration work beyond a deep clean, such as replacing contaminated wall insulation.

Scientists and remediation professionals have clashed over which contaminants homeowners ought to test for after a fire. Just last week, researchers hotly debated the thoroughness of the contamination testing at Palisades Charter High School’s campus. The school district decided it was safe for students to return; in-person classes began Tuesday.

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Harabedian hopes the new guidelines could solidify the state’s long-standing policy to conduct comprehensive, post-fire soil testing.

Not long after the federal government refused to adhere to the state’s soil testing policy, Nancy Ward, the former director of the California Governor’s Office of Emergency Services, had privately contemplated ending state funding for post-fire soil testing as well, according to an internal memo obtained by The Times.

“That debate, internally, should have never happened,” Harabedian said. “Obviously, if we have statewide standards that say, ‘This is what you do in this situation,’ then there is no debate.”

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Expiration of federal health insurance subsidies: What to know in California

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Expiration of federal health insurance subsidies: What to know in California

Thousands of middle-class Californians who depend on the state-run health insurance marketplace face premiums that are thousands of dollars higher than last year because enhanced federal subsidies that began during the COVID-19 pandemic have expired.

Despite fears that more people would go without coverage with the end of the extra benefits, the number enrolling in Covered California has held steady so far, according to state data.

But that may change.

Jessica Altman, executive director of Covered California, said that she believes the number of people dropping their coverage could increase as they receive bills with their new higher premiums in the mail this month. She said better data on enrollment will be available in the spring.

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Altman said that even though the extra benefits ended Dec. 31, 92% of enrollees continue to receive government subsidies to help pay for their health insurance. Nearly half qualify for health insurance that costs $10 or less per month. And 17% of Californians renewing their Covered California policies will pay nothing for premiums if they keep their current plan.

The deadline to sign up for 2026 benefits is Saturday.

Here’s help in sorting out what the expiration of the enhanced subsidies for insurance provided under the Affordable Care Act, often called Obamacare, means in the Golden State.

What expired?

In 2021, Congress voted to temporarily to boost the amount of subsidies Americans could receive for an ACA plan. The law also expanded the program to families who had more money. Before the vote, only Americans with incomes below 400% of the federal poverty level — currently $62,600 a year for a single person or $128,600 for a family of four — were eligible for ACA subsidies. The 2021 vote eliminated the income cap and limited the cost of premiums for those higher-earning families to no more than 8.5% of their income.

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How could costs change this year for those enrolled in Covered California?

Anyone with income above 400% of the federal poverty level no longer receives subsidies. And many below that level won’t receive as much assistance as they had been receiving since 2021. At the same time, fast-rising health costs boosted the average Covered California premium this year by more than 10.3%, deepening the burden on families.

How much would the net monthly premium for a Los Angeles couple with two children and a household income of $90,000 rise?

The family’s net premium for the benchmark Silver plan would jump to $699 a month this year from $414 a month last year, according to Covered California. That’s an increase of 69%, costing the family an additional $3,420 this year.

Who else could face substantially higher health bills?

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People who retired before the Medicare-qualifying age of 65, believing that the enhanced subsidies were permanent, will be especially hit hard. Those with incomes above 400% of the federal poverty level could now be facing thousands of dollars in additional health insurance costs.

How did enrollment in Covered California change after the enhanced subsidies expired on Dec. 31?

As of Jan. 17, 1,906,033 Californians had enrolled for 2026 insurance. That’s less than 1% lower than the 1,921,840 who had enrolled by this time last year.

Who depends on Covered California?

Enrollees are mostly those who don’t have access to an employer’s health insurance plan and don’t qualify for Medi-Cal, the government-paid insurance for lower-income people and those who are disabled.

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An analysis by KFF, a nonprofit that provides health policy information, found that nearly half the adults enrolled in an ACA plan are small-business owners or their employees, or are self-employed. Occupations using the health insurance exchanges where they can buy an ACA plan include realtors, farmers, chiropractors and musicians, the analysis found.

What is the underlying problem?

Healthcare spending has been increasing faster than overall inflation for years. The nation now spends more than $15,000 per person on healthcare each year. Medical spending today represents about 18% of the U.S. economy, which means that almost one out of every five dollars spent in the U.S. goes toward healthcare. In 1960, health spending was just 5% of the economy.

What has California done to help people who are paying more?

The state government allocated $190 million this year to provide subsidies for those earning up to 165% of the federal poverty level. This money will help keep monthly premiums consistent with 2025 levels for those with an annual income of up to $23,475 for an individual or $48,225 for a family of four, according to Covered California.

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Where can I sign up?

People can find out whether they qualify for financial help and see their coverage options at the website CoveredCA.com.

What if I decide to go without health insurance?

People without insurance could face medical bills of tens of thousands of dollars if they become sick or get injured. And under California state law, those without coverage face an annual penalty of at least $900 for each adult and $450 for each child.

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Department of Education finds San Jose State violated Title IX regarding transgender volleyball player

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Department of Education finds San Jose State violated Title IX regarding transgender volleyball player

The U.S. Department of Education has given San José State 10 days to comply with a list of demands after finding that the university violated Title IX concerning a transgender volleyball player in 2024.

A federal investigation was launched into San José State a year ago after controversy over a transgender player marred the 2024 volleyball season. Four Mountain West Conference teams — Boise State, Wyoming, Utah State and Nevada-Reno — each chose to forfeit or cancel two conference matches to San José State. Boise State also forfeited its conference tournament semifinal match to the Spartans.

The transgender player, Blaire Fleming, was on the San José State roster for three seasons after transferring from Coastal Carolina, although opponents protested the player’s participation only in 2024.

In a news release Wednesday, the Education Department warned that San José State risks “imminent enforcement action” if it doesn’t voluntarily resolve the violations by taking the following actions, not all of which pertain solely to sports:

1) Issue a public statement that SJSU will adopt biology-based definitions of the words “male” and “female” and acknowledge that the sex of a human — male or female — is unchangeable.

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2) Specify that SJSU will follow Title IX by separating sports and intimate facilities based on biological sex.

3) State that SJSU will not delegate its obligation to comply with Title IX to any external association or entity and will not contract with any entity that discriminates on the basis of sex.

4) Restore to female athletes all individual athletic records and titles misappropriated by male athletes competing in women’s categories, and issue a personalized letter of apology on behalf of SJSU to each female athlete for allowing her participation in athletics to be marred by sex discrimination.

5) Send a personalized apology to every woman who played in SJSU’s women’s indoor volleyball from 2022 to 2024, beach volleyball in 2023, and to any woman on a team that forfeited rather than compete against SJSU while a male student was on the roster — expressing sincere regret for placing female athletes in that position.

“SJSU caused significant harm to female athletes by allowing a male to compete on the women’s volleyball team — creating unfairness in competition, compromising safety, and denying women equal opportunities in athletics, including scholarships and playing time,” Kimberly Richey, Education Department assistant secretary for civil rights, said.

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“Even worse, when female athletes spoke out, SJSU retaliated — ignoring sex-discrimination claims while subjecting one female SJSU athlete to a Title IX complaint for allegedly ‘misgendering’ the male athlete competing on a women’s team. This is unacceptable.”

San José State responded with a statement acknowledging that the Education Department had informed the university of its investigation and findings.

“The University is in the process of reviewing the Department’s findings and proposed resolution agreement,” the statement said. “We remain committed to providing a safe, respectful, and inclusive educational environment for all students while complying with applicable laws and regulations.”

In a New York Times profile, Fleming said she learned about transgender identity when she was in eighth grade. “It was a lightbulb moment,” she said. “I felt this huge relief and a weight off my shoulders. It made so much sense.”

With the support of her mother and stepfather, Fleming worked with a therapist and a doctor and started to socially and medically transition, according to the Times. When she joined the high school girls’ volleyball team, her coaches and teammates knew she was transgender and accepted her.

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Fleming’s first two years at San José State were uneventful, but in 2024 co-captain Brooke Slusser joined lawsuits against the NCAA, the Mountain West Conference and representatives of San José State after alleging she shared hotel rooms and locker rooms with Fleming without being told she is transgender.

The Education Department also determined that Fleming and a Colorado State player conspired to spike Slusser in the face, although a Mountain West investigation found “insufficient evidence to corroborate the allegations of misconduct.” Slusser was not spiked in the face during the match.

President Trump signed an executive order a year ago designed to ban transgender athletes from competing on girls’ and women’s sports teams. The order stated that educational institutions and athletic associations may not ignore “fundamental biological truths between the two sexes.” The NCAA responded by banning transgender athletes.

The order, titled “Keeping Men Out of Women’s Sports,” gives federal agencies, including the Justice and Education departments, wide latitude to ensure entities that receive federal funding abide by Title IX in alignment with the Trump administration’s view, which interprets a person’s sex as the gender they were assigned at birth.

San José State has been in the federal government’s crosshairs ever since. If the university does not comply voluntarily to the actions listed by the government, it could face a Justice Department lawsuit and risk losing federal funding.

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“We will not relent until SJSU is held to account for these abuses and commits to upholding Title IX to protect future athletes from the same indignities,” Richey said.

San José State was found in violation of Title IX in an unrelated case in 2021 and paid $1.6 million to more than a dozen female athletes after the Department of Justice found that the university failed to properly handle the students’ allegations of sexual abuse by a former athletic trainer.

The federal investigation found that San José State did not take adequate action in response to the athletes’ reports and retaliated against two employees who raised repeated concerns about Scott Shaw, the former director of sports medicine. Shaw was sentenced to 24 months in prison for unlawfully touching female student-athletes under the guise of providing medical treatment.

The current findings against San José State came two weeks after federal investigators announced that the California Community College Athletic Assn. and four other state colleges and school districts are the targets of a probe over whether their transgender participation policies violate Title IX.

The investigation targets a California Community College Athletic Assn. rule that allows transgender and nonbinary students to participate on women’s sports teams if the students have completed “at least one calendar year of testosterone suppression.”

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Also, the Education Department’s Office of Civil Rights has launched 18 Title IX investigations into school districts across the United States on the heels of the Supreme Court hearing oral arguments on efforts to protect women’s and girls’ sports.

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