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Oregon health officials investigate rare brain disease blamed for two deaths

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Oregon health officials investigate rare brain disease blamed for two deaths

Health officials in Hood River County, Ore., are investigating three cases of a rare and fatal brain disease known as Creutzfeldt-Jakob disease.

Two people have died and a third person is showing symptoms consistent with the disease. The disease has been confirmed in one of the deceased through an autopsy; the other two cases are considered probable, according to a statement from the Hood River County Health Department.

All three cases were diagnosed in the last eight months. County health officials declined to provide particulars about the individuals, such as their age, gender or town of residence.

“At this time, there is no identifiable link between these three cases,” a Hood River County statement said. The county has a population of about 24,000.

Creutzfeldt-Jakob disease is a neurodegenerative disorder caused by misfolded proteins known as prions. These prions lead to rapid brain deterioration, resulting in severe neurological symptoms and death. Although the disease is known for its sporadic occurrence, clusters raise concerns among public health officials about potential environmental or dietary exposure.

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Symptoms include issues with memory, walking, coordination, speech and behavior changes, according to experts. It does not spread through the air, water, touch or social contact, according to Hood River County health officials.

The disease is considered incurable and is always fatal. Roughly 350 cases are diagnosed in the United States every year, according to the National Institutes of Health.

The disease is rare in people, affecting roughly 1.4 people per million. However, because the disease takes years to develop, any person’s chance of developing the disease is closer to 1 in 5,000 or 6,000, said Michael Geschwind, a professor of neurology at UC San Francisco in the Memory and Aging Center.

The disease is similar to chronic wasting disease, or CWD, which is also a prion-fueled disease, and was detected for the first time in wild deer in California and Washington last year.

CWD was first reported in 1967, in a captive Colorado deer. It has since spread to deer in 36 states. There are no known cases of the disease in Oregon wildlife.

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For decades there has been concern that CWD could move into human populations through the ingestion of contaminated meat.

That’s because in the 1980s, a prion disease in sheep, known as scrapies — which humans do not seem to get — moved into cows, and soon people throughout the United Kingdom, France and elsewhere were becoming infected with mad cow disease, or bovine spongiform encephalopathy.

Since then, public health officials from the Centers for Disease Control and Prevention and several states have been paying close attention to clusters of Creutzfeldt-Jakob disease — investigating outbreaks to determine whether infected deer, elk or moose meat was involved.

They — and researchers from other agencies, such as the U.S. Geological Survey’s National Wildlife Health Center — also have been monitoring wild deer populations and keeping tabs on hunters who may have been exposed.

Although widespread geographically throughout the United States and Canada, the disease is considered relatively rare in wild populations of deer, elk and moose, said Brian Richardson, the emerging-disease coordinator at the USGS wildlife center.

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“It may well be [in Oregon], but it’s hard to find rare events,” he said.

To date, there are no known incidents of people acquiring a prion disease by consuming deer, elk or moose meat, said Geschwind, the UCSF professor.

He said roughly 85% to 90% of Creutzfeldt-Jakob cases are considered sporadic, with no identified cause or source of infection. In 10% to 15% of the cases, the disease appears to be genetically inherited — with some people acquiring mutations associated with the disease.

However, there have been a few cases in which sources of infection or contamination have been identified, and almost all of them were from a medical mishap.

Prions are notoriously difficult to inactivate or destroy — withstanding standard sterilization techniques — and can remain intact for months and years on a surface, Geschwind said.

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In a small number of cases, he said, people acquired the disease as a result of contaminated and improperly cleaned surgical equipment. In a few other cases, it was acquired by people who used products — such as growth hormone, or who received corneal transplants — derived, inadvertently, from infected cadavers.

It’s these proteins’ durability and longevity that have many researchers worried. Studies have shown that deer that harbor the disease can pass the infectious prions to other deer through saliva, blood, urine and feces.

“So, if the animal is licking a plant or licking a salt lick, for example, and another animal comes along and licks that plant or salt lick, then that might be a way of spreading the disease,” Geschwind said.

In addition, the decomposing body of a deer that died of the disease can infect the surrounding environment where the animal expired — potentially contaminating plants, seeds, fungi and soil, Richardson said.

He said not only is there the issue of surface contamination, but also research has shown that the proteins can “be taken up via rootlets and deposited in aerial plant tissues. Whether these plants contribute to chronic wasting disease transmission and what type of risk these plants pose to humans remain open questions.”

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Geschwind noted that the work done by federal researchers to better understand the disease, provide diagnostic autopsies on presumptive cases, monitor wildlife and investigate clusters has provided a level of protection for the American public, which could be destabilized by proposed cuts to federal agencies.

“The idea of cutting government funding of rare disease is very short-sighted, because even though CJD is a rare disease, what we have learned from prion diseases has implications for all neurodegenerative diseases,” he said, noting Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease and multiple system atrophy.

“All these diseases act in a prion-like manner in which normal proteins misfold, and those misfolded proteins cause the cells to not work partly and lead to disease,” he said. “But the basic mechanism that we’ve learned from this very rare disease applies to diseases that are thousands of times more common. To get rid of the research? It’d be a very grave mistake.”

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For Oprah Winfrey, a croissant is now just a croissant — not a struggle

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For Oprah Winfrey, a croissant is now just a croissant — not a struggle

Yes, Oprah Winfrey has discussed her weight loss and weight gain and weight in general before — many, many times before. The difference this time around, she says, is how little food noise there is in her daily life, and how little shame. It’s so quiet, in fact, that she can eat a whole croissant and simply acknowledge she had breakfast.

“Food noise,” for those who don’t experience it, is a virtually nonstop mental conversation about food that, according to Tufts Medicine, rarely shuts up and instead drives a person “to eat when they’re not hungry, obsess over meals and feel shame or guilt about their eating habits.”

“This type of obsessive food-related thinking can override hunger cues and lead to patterns of overeating, undereating or emotional eating — especially for people who are overweight,” Tufts said.

Winfrey told People in an exclusive interview published Tuesday that in the past she would have been thinking, “‘How many calories in that croissant? How long is it going to take me to work it off? If I have the croissant, I won’t be able to have dinner.’ I’d still be thinking about that damn croissant!”

What has changed is her acceptance 2½ years ago that she has a disease, obesity, and that this time around there was something not called “willpower” to help her manage it.

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The talk show host has been using Mounjaro, one of the GLP-1 drugs, since 2023. The weight-loss version of Mounjaro is Zepbound, like Wegovy is the weight-loss version of Ozempic. Trulicity and Victroza are also GLP-1s, and a pill version of Wegovy was just approved by the FDA.

When she started using the injectable, Winfrey told People she welcomed the arrival of a tool to help her get away from the yo-yo path she’d been on for decades. After understanding the science behind it, she said, she was “absolutely done with the shaming from other people and particularly myself” after so many years of weathering public criticism about her weight.

“I have been blamed and shamed,” she said elsewhere in that 2023 interview, “and I blamed and shamed myself.”

Now, on the eve of 2026, Winfrey says her mental shift is complete. “I came to understand that overeating doesn’t cause obesity. Obesity causes overeating,” she told the outlet. “And that’s the most mind-blowing, freeing thing I’ve experienced as an adult.”

She isn’t even sharing her current weight with the public.

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Winfrey did take a break from the medication early in 2024, she said, and started to regain weight despite continuing to work out and eat healthy foods. So for Winfrey the obesity prescription will be renewed for a lifetime. C’est la vie seems to be her attitude.

“I’m not constantly punishing myself,” she said. “I hardly recognize the woman I’ve become. But she’s a happy woman.”

Winfrey has to take a carefully managed magnesium supplement and make sure she drinks enough water, she said. The shots are done weekly, except when she feels like she can go 10 or 12 days. But packing clothes for the Australian leg of her “Enough” book tour was an off-the-rack delight, not a trip down a shame spiral. She’s even totally into regular exercise.

Plus along with the “quiet strength” she has found in the absence of food noise, Winfrey has experienced another cool side effect: She pretty much couldn’t care less about drinking alcohol.

“I was a big fan of tequila. I literally had 17 shots one night,” she told People. “I haven’t had a drink in years. The fact that I no longer even have a desire for it is pretty amazing.”

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So back to that croissant. How did she feel after she scarfed it down?

“I felt nothing,” she said. “The only thing I thought was, ‘I need to clean up these crumbs.’”

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Owners of mobile home park destroyed in the Palisades fire say they’re finally clearing the debris

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Owners of mobile home park destroyed in the Palisades fire say they’re finally clearing the debris

Former residents of the Palisades Bowl Mobile Home Estates, a roughly 170-unit mobile home park completely destroyed in the Palisades fire, received a notice Dec. 23 from park owners saying debris removal would start as early as Jan. 2.

The Bowl is the largest of only a handful of properties in the Palisades still littered with debris nearly a year after the fire. It’s left the Bowl’s former residents, who described the park as a “slice of paradise,” stuck in limbo.

The email notice, which was reviewed by The Times, instructed residents to remove any burnt cars from their lots as quickly as possible, since contractors cannot dispose of vehicles without possessing the title. It followed months of near silence from the owners.

“The day before Christmas Eve … it triggers everybody and throws everybody upside down,” said Jon Brown, who lived in the Bowl for 10 years and now helps lead the fight for the residents’ right to return home. “Am I liable if I can’t get this done right now? Between Christmas and New Year’s? It’s just the most obnoxious, disgusting behavior.”

Brown is not optimistic the owners will follow through. “They’ve said things like this before over the years with a bunch of different things,” he said, “and then they find some reason not to do it.”

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Earlier this year, the Federal Emergency Management Agency denied requests from the city and the Bowl’s owners to include the park in the U.S. Army Corps of Engineers cleanup program, which FEMA said was focused on residential lots, not commercial properties. In a letter, FEMA argued it could not trust the owners of the Bowl to preserve the beachfront property as affordable housing.

A tattered flag waves in the wind at Asilomar View Park overlooking the Pacific Palisades Bowl Mobile Estates.

(Myung J. Chun/Los Angeles Times)

The Bowl, which began as a Methodist camp in the 1890s, was purchased by Edward Biggs, a Northern California real estate mogul, in 2005 and split between his first and second wives after his death in 2021. The family has a history of failing to perform routine maintenance and seeking to redevelop the park into a more lucrative resort community.

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After FEMA’s rejection, the owners failed to meet the City of L.A.’s debris removal deadlines. In October, the city’s Board of Building and Safety Commissioners declared the park a public nuisance alongside seven other properties, giving the city the authority to complete the debris removal itself and charge the owners the bill.

But the city has yet to find funds to front the work, which is expected to cost millions.

On Dec. 10, City Councilmember Traci Park filed a motion that would order the city to come up with a cost estimate for debris removal and identify funding sources within the city. It would also instruct the city attorney’s office to explore using criminal prosecution to address the uncleared properties.

The Department of Building and Safety did not immediately respond to requests for comment.

Despite the recent movement on debris removal, residents of the Palisades Bowl still have a long road ahead.

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Fire debris remains at Pacific Palisades Bowl Mobile Estates on Dec. 31, 2025.

On Wednesday, numerous burnt out vehicles still remained at the Pacific Palisades Bowl Mobile Estates. The owners instructed residents they must get them removed as quickly as possible.

(Myung J. Chun/Los Angeles Times)

In mobile home parks, tenants lease their spaces from the landowners but own the homes placed on the land. Before residents can start rebuilding, the Bowl’s owners need to replace or repair the foundations for the homes; fix any damage to the roads, utilities and retaining walls; and rebuild facilities like the community center and pool.

The owners have not responded to multiple requests for comment, but in February, Colby Biggs, Edward Biggs’ grandson, told CalMatters that “If we have to go invest $100 million to rebuild the park and we’re not able to recoup that in some fashion, then it’s not likely we will rebuild the park.”

Mobile home law experts and many residents doubt that the Biggs family would be able to convert the rent-controlled mobile home park into something else under existing law. The most realistic option, should the Biggs decide against rebuilding, would be to sell the park to another owner — or directly to the residents, a course of action the residents have been actively pursuing.

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The lack of communication and action from the owners has nonetheless left the Bowl’s eclectic former community of artists, teachers, surfers, first responders and retirees in limbo.

Many are running out of insurance money for temporary housing and remain unsure whether they’ll ever be able to move back.

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Video: Drones Detect Virus in Whale Blow in the Arctic

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Video: Drones Detect Virus in Whale Blow in the Arctic

new video loaded: Drones Detect Virus in Whale Blow in the Arctic

Scientists flew drones with petri dishes above several species of whales in northern seas to collect samples of whale blow, which they tested for four different viruses. For the first time in the Arctic, researchers found cetacean morbillivirus, a highly infectious and deadly virus for marine mammals.

By Jamie Leventhal and Alexa Robles-Gil

January 2, 2026

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