Science
In 'concerning development,' officials say H5N1 bird flu has infected a pig in Oregon
Oregon state and federal officials confirmed Wednesday that H5N1 bird flu was found in a pig living Crook County — the first such swine infection reported in the current outbreak.
The strain of bird flu virus in the pig is slightly different than the one that has been plaguing dairy cows in California and other states, which is known as B3.13. Instead, it is called D1 and originates from wild birds that likely came along the migratory Pacific flyway.
Both strains are H5N1; they just followed slightly different evolutionary trajectories, which is reflected in their genetic sequence.
Finding the flu virus in a pig, regardless of the strain, is a concerning development, say scientists.
“This is one big event that everyone has feared,” Rick Bright, a virologist and the former head of the U.S. Biomedical Advanced Research and Development Authority.
Swine are considered by health officials to be efficient influenza mixing bowls: They are susceptible to both avian and human flu viruses and can potentially provide an opportunity for different viruses to exchange genetic materials and become a greater threat to humans.
“Experts and commentators have minimized the outbreak to date, saying, ‘but it’s not in pigs yet.’ Well, now it seems to be, and just in time for the other critical ingredient to brew a pandemic virus … seasonal human flu viruses,” Bright said.
He said it’s critical that federal authorities move quickly and transparently.
“We cannot afford to keep playing a wait and see game,” he said. “We all know how quickly this virus can emerge and spread. We must immediately remove it from these farms, increase all surveillance, and begin planning actions for a larger response. … We cannot afford to do wait and see … again. We need to act now.”
John Korslund, a retired U.S. Department of Agriculture veterinarian epidemiologist, was a bit more circumspect.
According to officials, the infected pig was one of five living on small farm. All pigs were tested and euthanized. Results for two of the other pigs were negative, while the others are pending. In addition, federal authorities say only “low viral levels” were detected in the samples.
Korslund said this suggests the virus may require close contact, such as shared water, to move.
“I’ll be more concerned if it travels by aerosol to a confinement building,” he said, adding that a pig serving as mixing vessel is “not as likely in backyard herds — a bigger risk in commercial herds where flu is more endemic.”
The Oregon farm, which is located in an area just east of Bend, is not a commercial operation, according to the U.S. Department of Agriculture. It’s animals were not destined for commercial food production.
As a result, federal officials say there is no concern about the safety of the nation’s pork supply. They also note that cooking foods properly and pasteurizing dairy products inactivates the virus.
The farm where the pigs were living is the same one where 70 infected “backyard birds” were tested and euthanized last week after H5N1 was detected. The farm is under quarantine and the state’s department of agriculture is surveilling the area.
Those birds had the D1 version, which suggests they were not infected by dairy cows. Instead, it is likely they got it from wild birds.
“Based on recent diagnostic results, it’s apparent that migratory waterfowl are moving this new ‘D’ genotype down the Pacific Flyway,” said Bryan Richards, the Emerging Disease Coordinator at the U.S. Geological Survey’s National Wildlife Health Center.
In the past two weeks, there have been several outbreaks in commercial and backyard flocks in British Columbia, Washington and Oregon. California’s state veterinarian, Rebecca Jones, told The Times on Tuesday that a small backyard flock in Santa Rosa was also infected by the D1 strain.
That flock is not listed on the USDA’s website.
In addition, two commercial chicken farms in California’s Kings County, and a backyard flock in Tulare County, were reported infected on Tuesday. Again, the particular strains of H5N1 in those birds has not been identified.
Scientists are frustrated that genetic sequencing has not been forthcoming on some of these latest outbreaks.
“The big deal for me,” about the pig, said Korslund, is the “unwillingness to name the clade. Was it the dairy clade or something else? We also have another poultry outbreak in Oregon with dairy herds around that no one has owned up to [regarding] the sub-clade. If it is B3.13, they need to test dairy herds.”
A 2017 information sheet on agriculture in Crook County noted there were 47,399 cows and calves in the county.
According to the USDA, there have been 393 herds infected with H5N1 since March across 14 states — not including Oregon. Almost half of those — 193 — are in California.
Asked if a new strain of H5N1 in the mix was going to complicate the situation, Maurice Pitesky, an associate professor with a research focus on poultry health and food-safety epidemiology at UC Davis, said yes.
“This is year three of migration, where the virus seems to be coming back down” via birds who summered in the Arctic and swapped viruses, he said. “If that keeps happening, it makes it much more challenging to stop.”
He said that a few years ago, he worked on a computer model that could predict where the virus would show up as birds migrated south. He said it worked, and now people are asking him to develop another.
“I can’t,” he said. “It’s too complex now. Now it’s in urban wastewater, it’s in wild mammals. It’s in dairy cows. It’s in song birds. It’s in waterfowl and shore birds. It’s in marine mammals … We’ve never had anything like this before at a species level, at a geographical level, and at a food security level. Wow.”
Science
A tale worth telling of four women scientists whose names you should know but don't
Book Review
Sisters in Science: How Four Women Physicists Escaped Nazi Germany and Made Scientific History
By Olivia Campbell
Park Row Books: 368 pages, $32.99
If you buy books on our site, The Times may earn a commission from Bookshop.org, whose fees support independent bookstores.
You might have heard of Lise Meitner. A native of Austria, she was the first woman to become a full professor of physics in Germany. She also helped discover nuclear fission. Yet the 1944 Nobel Prize for Chemistry for that accomplishment went solely to her longtime collaborator, Otto Hahn.
Meitner battled misogyny and sexism at every stage of her illustrious career. But growing antisemitism and the 1933 Nazi takeover of Germany were an even higher-order problem. Although she was a convert to Lutheranism, her Jewish heritage endangered her. With the help of friends, she was able to flee in 1938 to neutral Sweden, where she was safe but scientifically isolated. “I can never discuss my experiments with anyone who understands them,” she wrote to fellow physicist Hedwig Kohn.
In “Sisters in Science,” Olivia Campbell tells the intertwined stories of Meitner and three other notable, but lesser known, women physicists from Germany: Kohn, Hertha Sponer and Hildegard Stücklen. Only Kohn was Jewish, but the Third Reich’s hostility to women academics cost the other two jobs as well.
All three eventually made it to the United States, where they pursued their careers and continued to support one another (and Meitner too). Kohn, the last to escape, didn’t make it out of Europe until 1940. She endured two months of arduous travel through the Soviet Union and Japan and across the Pacific Ocean, barely surviving the ordeal.
Theirs is an inspiring tale, and well worth telling — all the more so because, as Campbell notes in her dedication, so many other women academics were murdered by the Nazis. “Their absence haunts this book; the rippling impact of their loss affects us all,” she writes.
But its intrinsic interest notwithstanding, “Sisters in Science” is a sometimes frustrating read. Part of the problem is its ambitious scope. Group biography is a tricky genre. Campbell has to meld four narrative arcs: parallel at times, overlapping at others, but also divergent. A more elegant stylist, or a true adept of narrative nonfiction, might have managed to integrate these stories more seamlessly. It doesn’t help that Campbell refers to her protagonists by their first names — and three of the four begin with the letter “H.”
Explaining the physics to a lay audience is another challenge, perhaps an insuperable one. Campbell attempts it only nominally. The idea of fission, the splitting of atomic nuclei and resulting production of vast amounts of energy, is more or less intelligible. But the accomplishments of the other three physicists, who worked in spectroscopy, optics and astrophysics, are harder to grasp.
The book also would have benefited from better copy editing and fact-checking. Whatever her bona fides as a science journalist, Campbell is not at home in Holocaust history. One example: Campbell locates Dachau, the Nazis’ first concentration camp, in Oranienburg, a suburb of Berlin. Dachau opened in 1933 in the town of Dachau, near Munich. Oranienburg was actually the site of another eponymous camp and then, in 1936, Sachsenhausen.
There are other errors and infelicities. Campbell continually refers to Kristallnacht, the November 1938 Nazi pogrom, as “the Kristallnacht.” A more serious lapse is her anachronistic suggestion that, in 1938, Meitner feared being deported to a “death camp.” Camps such as Dachau and Sachsenhausen were brutal, often murderous places, but in the 1930s, they mostly housed Nazi political opponents (some of them Jewish). Jews were not yet being deported from Germany, and the six death camps dedicated to their extermination — places such as Sobibor, Treblinka and Auschwitz-Birkenau, all in Poland — did not become operational until the early 1940s.
It is also somewhat crude, and arguably inaccurate, to say that Kristallnacht “exposed the Nazis’ true agenda for the Jewish people: they wanted them all dead.” Despite the growing virulence of anti-Jewish persecution, that goal was not yet clear, and not yet official policy. In fact, though some were killed, most of the 30,000 or so Jewish men rounded up and taken to concentration camps during Kristallnacht were released on the condition that they emigrate.
Presumably Campbell is on firmer ground elsewhere — in noting, for instance, the difficulties that women scientists faced in Germany, including fights for pay, lab space and recognition; and in emphasizing the ways that they, and a few sympathetic male colleagues, helped one another endure, flourish and eventually escape.
When she first became Hahn’s assistant in Berlin, for example, Meitner was exiled from the main lab and stuck in a basement workshop with no nearby restroom. She ultimately rose to head the physics department at Berlin’s Kaiser Wilhelm Institute for Chemistry, a post she retained even after her Nazi-era dismissal from the University of Berlin.
Some male scientists were dead set against women. Others, such as Max Planck, welcomed collaboration from only the most exceptional of their female peers. One heroic supporter of women in science was the Nobel laureate James Franck. A German Jew, he resigned his post at the University of Göttingen before he could be fired, immigrated to the United States via Denmark, and was later instrumental in aiding colleagues, including women, who remained behind.
Franck and Sponer, his onetime assistant, were especially close — both friends and scientific collaborators. After a stint at the University of Oslo, Sponer accepted a position at North Carolina’s Duke University in 1936, and began working with Edward Teller, the eventual creator of the hydrogen bomb, “on the vibrational excitation of polyatomic molecules by electron collisions.”
Only after Franck’s wife died in 1942 did his long-germinating romance with Sponer come to fruition. He remained at the University of Chicago, and she at Duke. But in 1946, they married, and in Campbell’s sympathetic telling, experienced true happiness amid the sorrows around them.
Julia M. Klein is a cultural reporter and critic in Philadelphia.
Science
Doctor surrenders license after allegations that he sexually abused patients and employees
A longtime internist who founded a chain of Southern California clinics has surrendered his medical license after an accusation from the state medical board that he sexually assaulted three patients, two of whom worked for his clinics.
Dr. Mohammad Rasekhi signed an agreement to give up his medical license last month, weeks after the Medical Board of California filed an accusation against him detailing allegations that Rasekhi sexually abused three women while they were under his care.
Rasekhi denies all the allegations, his attorney Peter Osinoff said this week. He chose to waive his rights to a hearing and retire from medicine, a decision Osinoff said his client had been considering for some time.
“For him to spend his retirement money litigating over a license he no longer uses is not a good use of money,” Osinoff said. The surrender took effect Dec. 2.
Rasekhi was the founder and chief medical officer of Southern California Medical Center, a group of general practice clinics with locations in El Monte, Van Nuys, Pico Rivera, Woodland Hills, Pomona and Long Beach.
Sheila Busheri, co-founder of Southern California Medical Center and Rasekhi’s spouse, declined to comment.
In a document filed Oct. 3, the state medical board accused Rasekhi of sexual exploitation and gross negligence in his treatment of three patients.
The first became a primary care patient of Rasekhi’s around 2005, when she was 12 years old. In 2016, she accepted a job at SCMC while still seeing Rasekhi for her medical care.
Soon after, Rasekhi began making sexually suggestive comments to her at work, the document states. These progressed to unwanted sexual contact the woman endured for fear of losing her job, according to the complaint. The abuse continued until she went on medical leave in 2020.
The medical board reviewed records of the woman’s doctor appointments with Rasekhi. According to her chart, Rasekhi performed breast exams on the patient during visits for seemingly unrelated complaints such as back pain and hair loss, the accusation states.
“Respondent denied performing breast exams during those visits and conceded that the medical record does not accurately reflect the details about the visit or the examinations actually performed,” the complaint states.
A second patient began seeing Rasekhi in 2016 at the age of 62. In September 2017, the complaint states, Rasekhi arrived unannounced at the patient’s home.
“After entering Patient 2’s home and without Patient 2’s consent and over Patient 2’s protests, Respondent made sexual advances towards, and had sexual contact with, Patient 2,” the complaint said.
A third patient was employed at SCMC from 2007 to 2017, and became a patient of Rasekhi’s in 2015. Rasekhi made frequent suggestive comments at work that escalated into advances and sexual contact that continued until her resignation, the complaint stated.
A woman whose employment dates matched those of the third patient settled with Rasekhi, Busheri and SCMC for $3.5 million in 2019, according to a report in the Daily Journal.
Science
Avocados, salmon, strawberry yogurt: Which of these meets FDA's new definition of a “healthy” food?
In an effort to improve American diets, the U.S. Food and Drug Administration Thursday released a new definition of what it means for a food to qualify as “healthy.”
Products like fruit-flavored yogurt, fortified white bread and sweetened energy bars will no longer be allowed to label themselves as healthy if they exceed certain limits on saturated fat, sodium and added sugars.
At the same time, foods like salmon, almonds and even water will qualify as healthy for the first time.
The new definition reflects the advice offered in the Dietary Guidelines for Americans, which are produced by the Department of Agriculture and the Department of Health and Human Services. The hope is that consumers who consider health claims on packaged foods while filling their grocery carts will be steered toward a more nutritious eating pattern, the FDA said.
There’s no question that Americans can use some help with their diets. For example, less than half of U.S. adults eat a piece of fruit on any given day, and only 12% consume the recommended 1.5 to 2 cups of fruit per day, according to national surveys conducted by the Centers for Disease Control and Prevention. Americans are even further off the mark with vegetables, with only 10% meeting the target of 2 to 3 cups per day.
On the other hand, 90% of us eat too much sodium, 75% eat too much saturated fat and 63% eat too many added sugars, the FDA said.
The new definition of healthy foods aims to turn that around by excluding foods with excess sodium, saturated fat and added sugars even if they also contain valuable nutrients like protein and whole grains.
The specific limits vary depending on food groups. The limits will also depend on whether a product is an individual food (like cheese), a “mixed product” (like trail mix) or a complete meal (like a frozen dinner).
For instance, in order for a dairy product such as yogurt to qualify as healthy, a single 2/3-cup serving can’t have more than 5% of the recommended daily amount of added sugars, 10% of the recommended daily amount of sodium or 10% of the recommended daily amount of saturated fat.
Those limits translate to 2.5 grams of added sugars, 230 milligrams of sodium and 2 grams of saturated fat. A single serving of Chobani strawberry Greek yogurt would miss the mark because it contains 9 grams of added sugars. So would Chobani’s “less sugar” variety, which has 5 grams of added sugars.
Sugar, salt and fat are only part of the new criteria. To meet the new definition of healthy, foods must contain a minimum amount of protein, whole grains, fruit, vegetables or fat-free or low-fat dairy, the FDA said.
Whole foods like eggs, beans, seafood and nuts will automatically qualify as healthy if they are sold with no added ingredients (except for water). That makes foods like avocados, olive oil and higher-fat fish like salmon eligible to be labeled as healthy for the first time. Fruits, vegetables and fish can make the cut if they are fresh, frozen or canned, making them accessible to people on a range of budgets, the agency said.
However, products like fortified breads, cereals, fruit snacks, granola bars and fruit punch will lose the label unless they are reformulated to meet the new definition.
Nancy Brown, chief executive of the American Heart Assn., said the new definition was long overdue and hopes it will improve Americans’ diets by motivating food manufacturers to create healthier products. However, she added that it would be more meaningful to require products to carry a nutrition label on the front of their packages, which she believes would make it easier for consumers to identify and select healthier options.
The previous definition of healthy foods, which was issued in 1994, focused more on total fat and cholesterol. Since then, nutrition scientists have recognized that not all fats should be treated the same, and that unsaturated fats found in nuts, seeds, fish and certain vegetable oils can lower disease risk.
The old definition also required foods to provide at least 10% of the recommended daily amount of vitamin A, vitamin C, calcium, iron, protein or fiber. The FDA said it is shifting its focus from specific nutrients to larger food groups in order to help consumers build a healthy dietary pattern.
Poor diet is a risk factor for many of the leading causes of death in the U.S., including heart disease, stroke, diabetes and some types of cancer.
Food manufacturers will have three years to conform to the new definition, the FDA said, though those that meet the new criteria don’t have to wait that long to start using the “healthy” label.
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