Science
A Scientist Is Paid to Study Maple Syrup. He’s Also Paid to Promote It.
For more than a decade, Navindra Seeram, a biomedical researcher, has praised maple syrup, calling it a “hero ingredient” and “champion food” that could have wide-ranging health benefits.
Dr. Seeram, dean of the School of Pharmacy at the University of New England, has published more than three dozen studies extolling the power of maple. Much of his work has been bankrolled by Canada’s maple syrup industry and the Canadian and American governments.
At the same time, he has taken on another role: maple syrup pitchman.
“I am uniquely qualified as the world’s leading researcher on maple health benefits with the scientific reputation and credibility to promote the sales of maple products,” he has written in grant applications. He has assured leaders of the Canadian industry that he would always support maple from Quebec, according to emails obtained through a public records request.
As he straddles the realms of scientific inquiry and promotion, he has distorted the real-world implications of his findings and exaggerated health benefits, according to a review by The Examination and The New York Times of 15 years of his studies and public statements. In videos and press releases, he has suggested that consuming maple syrup may help stave off diseases including cancer, Alzheimer’s and diabetes. Other scientists told The Examination and The Times that they thought he had overstated his lab findings and made misleading claims.
Industry funding is commonplace in nutrition research and may become even more critical as scientists grapple with the Trump administration’s sweeping cuts. Dr. Seeram’s work shows the perils of intertwining science and salesmanship, propelling information that can shape consumer habits and public health.
At the University of Rhode Island, where he worked until last year, Dr. Seeram oversaw projects that were awarded $2.6 million in U.S. government funding, including a grant explicitly intended to increase maple syrup sales. That promotional work produced a stream of social media posts like, “Maple Syrup’s Benefits: Anti-Cancer, Anti-Oxidant, Anti-Inflammatory.”
In a video posted on YouTube in 2019, Dr. Seeram said nutrients in maple syrup could “potentially together prevent and/or delay the onset” of conditions such as “cardiovascular disease, metabolic syndrome, diseases of the brain and so on.”
But his studies have found something more limited: that maple syrup contains small amounts of polyphenols, compounds in plants that are generally considered beneficial. To demonstrate their effects, he tested highly concentrated maple extracts in lab settings — not people’s consumption of commercial maple syrup.
Dr. Seeram told The Examination that he believed in the power of natural medicines, which were part of his upbringing in South America. And he defended how he had spoken about his findings: “No one can go back to direct-quote from me to say, ‘It’s going to cure cancer, it’s going to cure diabetes.’”
His conclusions often include hedging language — that maple syrup “may” or “could” have meaningful health effects — or disclaimers recommending further study. But several researchers said that the caveats weren’t enough to counterbalance broad health claims, and that Dr. Seeram had leaped too far from lab findings to practical applications.
“They are framing it in a far more positive light than they should,” said Christopher Gardner, a nutrition researcher at Stanford.
In an interview, Dr. Seeram blamed a former colleague at the University of Rhode Island for stirring up what he said was unwarranted scrutiny of his work. A university official said the school had investigated and found no research misconduct.
At a maple industry conference in October, Dr. Seeram described his work as making “it simple for Mom to understand” that syrup is beneficial.
“We have to convince the consumer that this sugar is good for you,” he told an audience of maple farmers, and laid out how to reach the public: Studies like his would be published in peer-reviewed journals, leading to marketing and media coverage and inspiring consumers to buy.
The Quebec Maple Syrup Producers, an industry association that markets and regulates most of the world’s maple syrup, has long funded Dr. Seeram’s work. The association and the Canadian government have together provided at least $2.8 million for his research, according to a 2019 grant application. The association disputed that figure but would not provide details; neither would Dr. Seeram.
The association has also hired him for consulting and what it termed “PR activities” for at least a decade, according to emails and invoices. In 2023, his fees totaled $37,000, emails show.
In response to one of several emails from association officials thanking him for his work, he wrote in 2018 that he would “always work to find ways to promote maple products from Quebec.”
The maple association approached him in 2009, after the owners of POM Wonderful had funded and used some of his research on pomegranate to promote their juice during the pomegranate craze of the 2000s. (The Federal Trade Commission later issued a cease-and-desist order accusing the company of making misleading or false claims, based in part on a study he coauthored.)
Though Dr. Seeram had not previously researched maple, he told The Examination he was intrigued because he had recently moved to the Northeast, where it is an important agricultural product. Over the next couple of years, Dr. Seeram announced he had discovered dozens of polyphenols in maple syrup, including one his team named Quebecol.
Based on his lab tests of concentrated compounds, he began suggesting that maple syrup had wide-ranging applications for human health.
“Maple syrup is becoming a champion food,” he said in a 2011 press release. “Several of these compounds possess antioxidant and anti-inflammatory properties, which have been shown to fight cancer, diabetes and bacterial illnesses.”
But experts say the low levels of these compounds in syrup are unlikely to improve health. Dr. Seeram acknowledged in interviews that a person would have to consume gallons of maple syrup to get the nutritional equivalent of the extracts. He noted, as he often has, that he isn’t encouraging anyone to consume more sugar, merely to choose maple syrup over alternatives.
The U.S. Department of Agriculture, another important benefactor, awarded more than $2.6 million for Dr. Seeram’s work. This included nearly $500,000 in 2017 to study whether maple syrup extract could improve the health of obese mice. Their health did not improve, and in some cases worsened, according to study findings cited by a government website and a student dissertation. The results weren’t published in an academic journal. Dr. Seeram, who in recent weeks stopped responding to queries from The Examination and The Times, didn’t answer questions about this study.
In 2018, the U.S.D.A. awarded $500,000 to a group led by Dr. Seeram for a promotional campaign that would showcase maple research on a University of Rhode Island website. Dr. Seeram’s grant application said he would be responsible for translating the science into “lay-friendly terminology.”
The website, overseen by his team, called maple syrup “immensely healthy for you.” And though it carried disclaimers that more research was needed, it made misleading statements connecting studies of reduced-sugar maple extract to the consumption of maple syrup, such as: “Did you ever think that you could fight high blood sugar with some things as sugary and delicious as maple syrup?”
It also said the Quebecol compound could become a “potential cancer prevention drug,” noting that it looked “remarkably similar” to the breast cancer drug Tamoxifen — a comparison Dr. Seeram has also made in presentations.
In interviews, three cancer researchers called this comparison misleading. Geoffrey Greene of the University of Chicago said it was like expecting the brother of a concert violinist to also be a concert violinist because they looked similar.
When asked why he has used his research to promote maple products, Dr. Seeram said he was simply fulfilling the terms of the government grant. A U.S.D.A. spokeswoman said the University of Rhode Island was responsible for the website’s claims.
The university wouldn’t comment on the research. After inquiries from reporters, the website was taken down. The university said this was part of a broader effort to remove dormant pages.
One of Dr. Seeram’s studies involved giving maple syrup extract to genetically modified worms to examine Alzheimer’s-related effects. His team observed that some worms fared better, but on average they were worse off. Nevertheless, the top-line summary in Dr. Seeram’s paper, published in 2016 by the journal Neurochemical Research, ignored the negative results and said the syrup extract “showed protective effects” for the worms.
An industry association press release said maple syrup extract had prolonged the worms’ lives — even though on average they died sooner — with a disclaimer that more research was needed. That nuance was lost in headlines in Canada, India, England and the United States proclaiming that maple syrup could protect against Alzheimer’s.
Christopher Link of the University of Colorado Boulder, who pioneered Alzheimer’s research on that kind of worm, criticized the study, citing the lack of basic details like the number of worms tested and whether the experiment had been replicated. Dozens of plant extracts have produced positive results in similar experiments, Dr. Link said, but that doesn’t mean they have real-world applications.
In a statement, Julie Barbeau of the maple association said it adheres to strict ethics rules and has had “no influence whatsoever” on the scores of research projects it has backed.
At least a dozen of Dr. Seeram’s papers that the maple association says it funded didn’t disclose that relationship. Also not disclosed in his papers: his paid consultant role and a Canadian maple extract patent that names him and Ms. Barbeau as co-inventors.
Six publishers of Dr. Seeram’s work said they require authors to declare potential conflicts of interest. Dr. Seeram did not respond to questions about his disclosures.
In public statements, he has acknowledged receiving financial support from the maple association. And in earlier interviews, he said that industry funding is vital, because other research dollars are scarce. He also defended his patents, saying, “The driver here is not for me to get rich.” The maple association said it was protecting its intellectual property.
Last year, the association hailed a new study, which it funded, as the “first human clinical trial” of maple syrup.
Participants replaced a small amount of sugar in their diet with maple syrup — for instance, to sweeten coffee. The scientists told Newsweek that the results, published in The Journal of Nutrition, showed that maple syrup improved measures of blood sugar, blood pressure and fat, and might help lower the risk of diabetes and cardiovascular disease.
Dr. Seeram, who was not an author of the study, said the results validated his work.
But three independent experts who reviewed the research said the conclusions were overstated — emphasizing a few positive results among dozens of measures — and the study appeared to show no meaningful difference between maple syrup and refined sugar.
“They took it too far,” said Kimber Stanhope, a nutritional biologist at the University of California, Davis.
The lead researcher, André Marette of Laval University, said that while the differences between maple syrup and refined sugar were “modest,” they were meaningful. Through a public relations firm hired by the industry association, he said, “We were careful to state that the clinical relevance of the work will need to be further substantiated.”
In the meantime, the findings have reached the general public. “Sweet!” effused a headline in a women’s magazine last fall. “Maple Syrup in Coffee Could Help You Lose Weight.”
Mago Torres contributed reporting.
Science
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Science
Trump Plans to Fire F.D.A. Commissioner Marty Makary
President Trump has signed off on a plan to fire Dr. Marty Makary, commissioner of the Food and Drug Administration, after a series of clashes over vaping, oversight of the abortion pill and a series of new drug application denials that rattled biotech companies, according to a person briefed on the matter, who was not authorized to discuss it publicly.
Dr. Makary had a high profile for an F.D.A. commissioner, appearing frequently on television and podcasts to sell the work he was doing at the agency on improving the food supply, speeding up some drug approvals and trying to restore agency morale after thousands of staff members left.
He tried to walk the tightrope between the business-friendly Make America Great Again movement, pledging to get rid of regulations that slow down innovation and to attract more drug trials to the United States. He was an ally of Health Secretary Robert F. Kennedy Jr.’s Make American Healthy Again supporters, voicing the skepticism of the pharmaceutical industry and authorizing natural food dyes.
Ultimately, Dr. Makary’s efforts were not enough to overcome the grievances of a growing band of enemies focused on selling tobacco, opposing abortion and seeing biotech therapies authorized.
Mr. Trump’s decision to dismiss him was first reported by The Wall Street Journal.
The decision could still change, given Mr. Trump’s propensity to change his mind Dr. Makary has also proven persuasive with Mr. Trump in beating back previous efforts to oust him.
Leaving the White House Friday evening, Mr. Trump dismissed the idea that Dr. Makary would be fired.
“I’ve been reading about it, but I know nothing about it,” he said.
The White House has pressured Dr. Makary for months to authorize flavored e-cigarettes, according to a person close to the conversations. The approvals were a top wish of major tobacco companies that have been top donors to Mr. Trump. In March, the F.D.A. issued a memo saying that it would only authorize e-cigarettes in flavors such as mint, tea and spices. The memo said the fruit and candy flavors would be unlikely to pass muster, given their appeal to young people.
Pressure continued, though, and on Tuesday the F.D.A. authorized blueberry and mango flavored e-cigarettes by Glas, a small company based in Los Angeles.
Abortion foes including Susan B. Anthony Pro-Life America have continued to turn up the heat on Dr. Makary, reiterating their call for his firing on Thursday. The group’s leaders and others view Dr. Makary as dragging his feet on a safety review of the abortion pill mifepristone, which they viewed as a way to highlight what they believe are dangers of the drug. Former Vice President Mike Pence, who also opposes abortion rights, amplified criticism of Dr. Makary on social media as well.
The administration has been under pressure from conservatives to tighten regulations on the prescribing and dispensing of mifepristone. The Supreme Court is reviewing a federal appeals court ruling that temporarily blocked abortion providers from prescribing the drug through telemedicine and sending it to patients by mail.
Biotech companies and their investors have also raised alarms with the White House about agency decisions to reject a series of treatments for rare diseases. The F.D.A. typically turns down about 20 percent of the applications it receives for drug approvals from companies.
Dr. Makary has been aggressive in defending the decisions, which he said came from career scientists who found the medications ineffective.
Dr. Makary also had to contend with a health secretary who seemed to view the F.D.A. as an avenue for getting his favored products authorized, exemplified by Mr. Kennedy’s social media post saying that the agency would end its “war on” stem cell treatments, peptides and raw milk. Mr. Kennedy pushed the F.D.A. to reverse a 2023 ban and allow the use of a number of peptides, unproven compounds purported to offer anti-aging or muscle-recovery benefits.
Before leading the F.D.A., Dr. Makary was a cancer surgeon and health policy researcher at Johns Hopkins University School of Medicine. He was also the author of several books about the health care system.
Some of Dr. Makary’s more popular moves included encouraging broader use of hormone replacement products for women and lifting the F.D.A.’s warnings on them. He helped speed some promising drugs to market, including a pancreatic cancer therapy and the pill form of the popular GLP-1 weight loss drugs.
Science
Californians were aboard hantavirus-stricken cruise ship. Is there a risk to the public?
Some California residents were among the 147 passengers and staff aboard a luxury cruise ship stricken by a suspected outbreak of hantavirus that has left three people dead and several others severely ill, officials confirmed Thursday.
California public health officials say they are monitoring the situation after being notified by the U.S. Centers for Disease Control and Prevention that some state residents were passengers on the MV Hondius. The precise status of those individuals, however, remains murky.
Hantavirus is a rare but deadly disease that attacks the lungs and is typically contracted by humans through inhalation of particles contaminated with the urine, feces or saliva of a wild rodent.
However, Dr. Tedros Adhanom Ghebreyesus, director-general of the World Health Organization, confirmed Thursday that the Andes virus — a form of hantavirus that can spread from person to person — was involved in the outbreak.
Here’s what we know:
The MV Hondius cruise ship anchored at a port in Praia, Cape Verde, on Wednesday.
(Misper Apawu / Associated Press)
As its name suggests, the Andes virus is typically found in South America. The Dutch-flagged MV Hondius was on a 46-day journey that traveled from Antarctica with stops in Argentina.
In the case of human-to-human transmission, a person would first be infected by a wild rodent’s contaminated particles and then pass the infection to someone else, said Dr. Gaby Frank, director of the Johns Hopkins Special Pathogens Center.
“In previous outbreaks of Andes virus, transmission between people has been associated with close and prolonged contact, particularly among household members, intimate partners and people providing medical care,” Ghebreyesus said. “That appears to be the case in the current situation.”
None of the remaining passengers or crew members on the ship are symptomatic, he said.
The ship was not permitted to allow passengers to disembark at its original destination, Cape Verde, and is sailing for Spain’s Canary Islands.
“I want to be unequivocal here: This is not SARS-CoV-2. This is not the start of a COVID pandemic. This is an outbreak that we see on a ship. There’s a confined area,” Dr. Maria Van Kerkhove, who leads the WHO’s epidemic and pandemic management, said at a briefing. “This is not the same situation we were in six years ago. It doesn’t spread the same way like coronaviruses do.”
California passengers on the cruise
On April 1, 114 guests boarded the cruise ship in Ushuaia, Argentina. Twenty-three days later, 30 passengers — including six people from the United States — disembarked on a stop in St. Helena, a remote island about 1,100 miles off the coast of Africa, according to the cruise operator Oceanwide Expeditions.
Public health agencies in California, Georgia and Arizona were notified by the CDC that some of their residents were among the passengers on the cruise. It’s unclear whether these individuals disembarked on April 24, however.
The CDC is assisting local health authorities with monitoring California residents who were aboard the cruise, according to a statement by the California Department of Public Health on Friday.
As of Friday, one passenger has returned to their California residence and is in contact with local public health officials, and at least one other remains aboard the ship, according to the state agency.
“We understand that news of an unusual outbreak can be concerning,” said Dr. Erica Pan, director of the California Department of Public Health. “Unlike influenza and COVID-19, years of experience in South America have shown that this Andes hantavirus rarely spreads between people.”
Officials said the current public health protocol is to do daily symptom monitoring and reporting.
“As there are no known cases of Andes hantavirus infection from people without symptoms, and any spread has usually been limited to people with prolonged close contact with an ill person with this virus, the risk to the general public in California is extremely low,” the agency said in a statement.
In a statement earlier this week, the CDC also said that the risk to the American public “is extremely low” at this time.
“We urge all Americans aboard the ship to follow the guidance of health officials as we work to bring you home safely,” the agency said.
The others who exited the ship on April 24 were individuals from Canada, Denmark, Germany, the Netherlands, New Zealand, Switzerland, Sweden, Singapore, St. Kitts and Nevis, Turkey and the United Kingdom.
Of the remaining passengers still aboard the ship headed for Spain’s Canary Islands, California Department of Public Health said none were ill as of Friday.
How many people have been infected?
The number of lab-confirmed hantavirus cases has risen to five, according to the WHO. There are three additional suspected cases.
A timeline of reported cases of hantavirus aboard the cruise ship can be found here.
The WHO is monitoring reports of other people with symptoms “who may have had contact with one of the passengers. In each case, we are in close contact with the relevant authorities,” Tedros said.
The first passenger to have been infected, a Dutchman, became sick aboard the cruise ship on April 6 and died on April 11.
No samples were taken, because his symptoms were similar to other respiratory diseases. His widow left the ship with his body on April 24 during the scheduled stop at St. Helena.
“She deteriorated during a flight to Johannesburg on the 25th of April and died the next day,” Tedros said.
Before boarding the cruise ship, the Dutch couple had traveled through Argentina, Chile and Uruguay on a bird-watching trip, “which included visits to sites where the species of rat that is known to carry Andes virus was present,” Tedros said.
After leaving the ship, the woman was briefly aboard a KLM aircraft in Johannesburg bound for Amsterdam but was barred from the flight due to her medical condition, the airline said in a statement.
Dutch news outlets reported that a flight attendant on a KLM airplane — who briefly had contact with the widow — started feeling sick and had mild symptoms and was in isolation at a hospital in Amsterdam.
The flight attendant has since tested negative for the Andes virus, Dr. Jeremy Faust, an emergency medicine physician, wrote on his Substack blog, Inside Medicine, citing a text message sent to him by Tedros.
“It is still possible that the flight attendant contracted the Andes virus. However, given our understanding of the virus, this information means that the flight attendant’s symptoms are not caused by the Andes hantavirus, but by some other medical illness,” Faust wrote.
More cases may be reported, because the incubation period — the time it takes between exposure to the virus and the onset of illness — for the Andes strain of the hantavirus is up to six weeks.
What we know about hantavirus
There are roughly 50 identified species of hantavirus. The virus that’s found in the Americas tends to cause a cardiopulmonary syndrome, a condition that affects the heart and the lungs, according to Frank.
There have been 890 laboratory-confirmed cases of hantavirus disease reported in the U.S. since surveillance began in 1993, according to the most recent data from the CDC.
From 1980 to 2025, 99 California residents have been diagnosed with a hantavirus infection, according to the California Department of Public Health.
CDC officials said 38% of people who develop respiratory symptoms may die from the disease.
Still, the data suggest that contracting hantavirus is rare, said Dr. Afif El-Hasan, member of the American Lung Assn.’s national board of directors.
There is no vaccine or specific antiviral medicine for hantavirius.
Intensive-care treatment may include intubation and oxygen therapy, fluid replacement and use of medications to lower blood pressure, according to the American Lung Assn.
The signs of hantavirus
Early symptoms of hantavirus are similar to the flu and include fatigue, fever and muscle aches, according to the CDC. Symptoms start to develop within one to eight weeks after contact with an infected rodent.
Half of those who contract the virus also experience headaches, dizziness, chills, nausea, vomiting, diarrhea and abdominal pain.
Four to 10 days after the initial phase of the illness, another round of symptoms can develop, which include coughing, shortness of breath and possible tightness in the chest as the lungs fill with fluid.
Even though contracting hantavirus in the U.S. continues to be a rare event, El-Hasan said, people should take these initial symptoms seriously and promptly seek medical care.
How to protect yourself
Hantavirus cases can occur year-round, but the peak seasons in the United States are the spring and summer, which coincide with the reproductive seasons for deer mice.
To lessen your risk of infection, keep wild rodents out of your home and other enclosed spaces by sealing any holes and placing snap traps.
If you find evidence of mice, wear personal protective equipment and disinfect the area. When you’re done, put everything, including cleaning materials, in a bag and toss it in your trash bin.
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