Las Vegas Raiders at Indianapolis Colts odds, picks and predictions

The Indianapolis Colts (8-7) welcome the Las Vegas Raiders (7-8) to Lucas Oil Stadium Sunday. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze BetMGM Sportsbook’s lines around the Raiders vs. Colts odds, and make our expert NFL picks and predictions.

The Colts lost to the Atlanta Falcons 29-10 on the road Sunday in Week 16 action. They failed to cover as 3-point road underdogs. Indianapolis is 9-6 against the spread (ATS) this season and 4-3 ATS at home. It has covered 4 of its last 6 games. The Colts are led by QB Gardner Minshew, who has 2,940 passing yards and 17 total touchdowns.

The Raiders beat the Kansas City Chiefs 20-14 as 11-point road underdogs Monday in Week 16 action. Las Vegas has covered 2 straight games and is 8-5-2 ATS on the season. It has covered 5 of its last 7 and is 5-1-1 ATS in that span. The Raiders have had 4 players throw a pass this season but will be led by QB Aidan O’Connell, who has 1,675 passing yards through 9 starts.

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Raiders at Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 1:20 p.m. ET.

• Moneyline (ML): Raiders +165 (bet $100 to win $165) | Colts -200 (bet $200 to win $100)
• Against the spread (ATS): Raiders +4 (-110) | Colts -4 (-110)
• Over/Under (O/U): 42.5 (O: -110 | U: -110)

Raiders at Colts key injuries

Raiders

• RB Josh Jacobs (quad) doubtful
• C Andre James (ankle) questionable
• TE Michael Mayer (toe) out

Colts

• LB Cameron McGrone (illness) questionable
• CB Kenny Moore II (back) questionable
• RB Zack Moss (forearm) out
• WR Michael Pittman Jr. (concussion/shoulder) questionable
• OT Braden Smith (knee) questionable

Raiders at Colts picks and predictions

Prediction

Colts 27, Raiders 20

Moneyline

PASS.

The Colts have been solid at home but aren’t worth the slightly-too-expensive -200 value. Take them on the spread instead.

Against the spread

BET COLTS -4 (-110).

Indianapolis has not covered well nor played well on the road. Now, at home, it is a completely different team. It beat the Pittsburgh Steelers 30-13 in Week 15 and the Tampa Bay Buccaneers 27-20 in Week 12, its last 2 home games. It is 3-1 ATS over its last 4 home games.

While Vegas beat the Chiefs Monday, they haven’t performed well on the road when expected to. Las Vegas is 1-3-1 ATS on the road as a favorite or single-digit underdog. While O’Connell has provided more stability at quarterback, he has 8 touchdowns through the air and 7 picks.

Take the side better in this situation with the more reliable quarterback. Back COLTS -4 (-110).

Over/Under

LEAN OVER 42.5 (-110).

Las Vegas is just 4-11 O/U this season but has scored 83 points over its last 2 games. It is 2-2 O/U in its last 4. The Colts are 10-5 O/U and have gone Over in 4 of its last 5 games.

Indianapolis has scored or allowed at least 29 points in 4 straight games, ending with 30 or more on the board in 2 of its last 4. It has a competent offense that should bounce back in Week 17.

Take OVER 42.5 (-110).

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