Jacksonville Jaguars at Indianapolis Colts: Predictions, picks and odds for NFL Week 6 matchup

Already taking part in each other for the second time in six weeks, Trevor Lawrence and the Jacksonville Jaguars journey to Indianapolis to tackle Matt Ryan’s Colts in a pivotal AFC South matchup.

The Jaguars (2-3) dominated the Colts of their matchup earlier this season, however will the Colts (2-2-1) even the season sequence at residence? Lawrence, Christian Kirk and the Jaguars are on the heels of a crushing loss to the Houston Texans, whereas Indianapolis is coming off an unpleasant win in Denver in opposition to the Broncos. The sport is about to kick off Sunday at 1 p.m. ET from Lucas Oil Stadium.

This is a have a look at the betting particulars and USA TODAY’s NFL workers picks for the Jaguars vs. Colts Week 6 sport:

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NFL Week 6 odds, predictions and picks

Commanders vs. Bears | Patriots vs. Browns | Buccaneers vs. Steelers | Ravens vs. Giants | Vikings vs. Dolphins | Jets vs. Packers | 49ers vs. Falcons | Bengals vs. Saints | Jaguars vs. Colts | Cardinals vs. Seahawks | Panthers vs. Rams | Payments vs. Chiefs | Cowboys vs. Eagles | Broncos vs. Chargers

Lorenzo Reyes: Jaguars 17, Colts 14

Whereas the Jaguars have struggled during the last two weeks, their early-season success confirmed they are often aggressive. The secret’s limiting turnovers and placing Trevor Lawrence in a spot to get the ball out shortly. The Colts have so many points: turnover margin (-6), offensive line (tied for league-high 21 sacks allowed). They could win this sport straight up. I don’t assume they will cowl.

Safid Deen: Jaguars 21, Colts 17

The Jaguars had a irritating loss to the Texans final week, however Indianapolis has one of many league’s worst offenses. Give me Jacksonville on the street.

Story continues

Lance Pugmire: Jaguars 20, Colts 17

That is essentially the most unpredictable sport on the board because the Jaguars have floundered since their spectacular Week 3 triumph on the Chargers and the Colts’ offense – even with this week’s return of Jonathan Taylor – has been a punchline.

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This text initially appeared on USA TODAY: Jacksonville Jaguars at Indianapolis Colts: Recreation predictions, picks, odds