Health
What to know about actor Dave Coulier’s blood cancer: ‘Very aggressive’
Dave Coulier, 65, announced on Tuesday that he has stage 3 non-Hodgkin lymphoma.
The actor and comedian, best known for his role as Joey Gladstone in “Full House” from 1987 to 1995, said he was diagnosed in October after experiencing an upper respiratory infection caused by major swelling in his lymph nodes.
“Three days later, my doctors called me back, and they said, ‘We wish we had better news for you, but you have non-Hodgkin lymphoma, and it’s called B cell, and it’s very aggressive,’” he told People.
‘FULL HOUSE’ STAR DAVE COULIER DIAGNOSED WITH ‘VERY AGGRESSIVE’ CANCER
What is non-Hodgkin lymphoma?
Non-Hodgkin lymphoma (also known as non-Hodgkin’s lymphoma, NHL or lymphoma) is a blood cancer that originates in the white blood cells (lymphocytes) that are part of the body’s immune system, according to the American Cancer Society (ACS).
Dave Coulier, 65, announced on Tuesday that he has stage 3 non-Hodgkin lymphoma. (Getty Images)
Every year, more than 80,000 Americans are diagnosed with NHL.
“Non-Hodgkin lymphomas are a diverse group of white blood cell cancers that can vary greatly in terms of how aggressive or indolent they are,” Dr. Joshua Strauss, an attending hematologist and medical oncologist at Advanced Care Oncology and Hematology Associates of the Atlantic Medical Group in Morristown, New Jersey, told Fox News Digital.
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Patients with aggressive types of NHL may develop rapidly growing masses that they can feel, or they may experience more general symptoms, such as fevers, night sweats and unintentional weight loss, noted Strauss, who has not treated Coulier.
An important part of diagnosis is determining what type of lymphoma the patient has, according to the ACS.
Non-Hodgkin lymphoma (also known as non-Hodgkin’s lymphoma, NHL or lymphoma) is a blood cancer that originates in the white blood cells (lymphocytes) that are part of the body’s immune system. (iStock)
“The type of lymphoma depends on what type of lymphocyte is affected (B cells or T cells), how mature the cells are when they become cancerous and other factors,” the organization states on its website.
Stages and treatment
Like other cancers, lymphomas are assigned a stage, from 1 to 4.
People with stages 1 and 2 have “limited disease,” according to Strauss, while patients with stages 3 and 4 have “advanced disease,” where the disease has spread to multiple areas of the body.
Every year, more than 80,000 Americans are diagnosed with non-Hodgkin lymphoma.
“However, as opposed to some other cancers, prognosis in NHL is more affected by histopathology, which is the particular subtype as determined by the appearance of the cancer under the microscope,” the doctor said.
Depending on the subtype, some patients with stage 3 disease can have an “excellent prognosis,” Strauss said, with recent advances in treatment improving outcomes.
Aggressive non-Hodgkin lymphoma is typically treated with intravenous chemo-immunotherapy.
“This is a cocktail of various chemotherapy drugs combined with an immune treatment that attacks the cancer cells while trying to spare normal cells,” Strauss said.
Aggressive non-Hodgkin lymphoma is typically treated with intravenous chemo-immunotherapy. (iStock)
After several months of treatment, doctors typically use imaging to determine whether any cancer remains.
Coulier revealed in the “Full House Rewind” podcast that he started chemotherapy two weeks after his diagnosis, and preemptively shaved his head.
Who is at greatest risk?
While anyone can be diagnosed with NHL, there are several known risk factors.
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“People with autoimmune diseases or those who take medications to suppress the immune system may be at higher risk of developing NHL over time,” Strauss said.
“The type of lymphoma depends on what type of lymphocyte is affected (B cells or T cells), how mature the cells are when they become cancerous and other factors,” according to the American Cancer Society. (iStock)
Certain infections, such as HIV and Epstein-Barr infection, as well as exposure to chemicals such as pesticides, may increase risk, the doctor warned.
“While NHL can occur at any age, risk increases as we get older,” he said.
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The cancer type has also been associated with smoking and obesity, Strauss said — “so quitting smoking and maintaining a healthy weight may be protective.”
Coulier (left) is best known for his role as Joey Gladstone in “Full House” from 1987 to 1995 (right). (Getty Images)
Stephanie Giang-Paunon contributed reporting.
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Health
Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates
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In a dramatic turn of events that’s captured the attention of animal lovers worldwide, Punch — the young macaque at a zoo in Japan famous for his inseparable bond with a stuffed orangutan toy — has reached a major milestone in his journey toward social integration.
On Thursday, visitors and staff at the Ichikawa Zoological and Botanical Garden witnessed a breakthrough: Punch was seen cuddling with and hitching a ride on the back of a fellow macaque.
Punch’s story began with hardship. He was abandoned by his mother shortly after his birth in July 2025 — and to ensure his survival, zookeepers stepped in to hand-rear the primate.
On Jan. 19, 2026, the zoo officially began the process of reintegrating Punch into the “monkey mountain” enclosure.
The transition was initially fraught with tension.
Punch’s story began with hardship when he was abandoned by his mother shortly after he was born. To help him, zookeepers gave him a stuffed toy that he began dragging around everywhere he went. (David Mareuil/Anadolu via Getty Images)
As a hand-reared infant, Punch was bullied and ignored by the established group of monkeys.
He was often seen huddled alone with his orange plush companion while the rest of the troop interacted.
BABY MONKEY CARRIES FAITHFUL STUFFED COMPANION EVERYWHERE HE GOES, DRAWING CROWDS AT ZOO
In an official statement released Feb. 27, the Ichikawa Zoological and Botanical Garden detailed the meticulous care behind this process.
Previous viral videos showed Punch bullied by the rest of the troop, running to his plushy toy for comfort. (David Mareuil/Anadolu via Getty Images)
“From an animal welfare perspective, our primary goal is to reintegrate Punch with the troop,” the zoo said.
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The strategy involved nursing Punch within the enclosure, so the troop could recognize him as one of their own, and pairing him with a gentle young female macaque prior to his full release to build his confidence.
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The latest footage, captured by X user @tate_gf, suggested the zoo’s patience is paying off.
The video shows Punch seeking physical contact not from his toy, but from another monkey — eventually climbing onto its back for a vital social behavior for young macaques: the “piggyback ride.”
The zoo’s strategy appears to be paying off: Punch, shown at far left, was recently seen riding on the back of a fellow macaque. (David Mareuil/Anadolu via Getty Images)
While Punch still carries his stuffed toy for comfort during moments of perceived danger, the zoo remains optimistic about his progress.
The organization cited the successful 2009 case of Otome, another hand-reared macaque who eventually outgrew her stuffed toy, successfully integrated — and went on to raise four offspring of her own.
The zoo has had crowds coming to see Punch, with hundreds of people lining up to get inside to see the young star, according to reports.
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“I’m hoping Punch has a good life like everybody else does, and think he’s a cute little guy,” one person commented online.
“Such a precious baby,” another person wrote.
Health
ChatGPT could miss your serious medical emergency, new study suggests
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This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).
Artificial intelligence has been touted as a boon to healthcare, but a new study has revealed its potential shortcomings when it comes to giving medical advice.
In January, OpenAI launched ChatGPT Health, the medical-focused version of the popular chatbot tool.
The company introduced the tool as “a dedicated experience that securely brings your health information and ChatGPT’s intelligence together, to help you feel more informed, prepared and confident navigating your health.”
But researchers at the Icahn School of Medicine at Mount Sinai have found that the tool failed to recommend emergency care for a “significant number” of serious medical cases.
The study, published in the journal Nature Medicine on Feb. 23, aimed to explore how ChatGPT Health — which is reported to have about 40 million users daily — handles situations where people are asking whether to seek emergency care.
Artificial intelligence has been touted as a boon to healthcare, but a new study has revealed its potential shortcomings when it comes to giving medical advice. (iStock)
“Right now, no independent body evaluates these products before they reach the public,” lead author Ashwin Ramaswamy, M.D., instructor of urology at the Icahn School of Medicine at Mount Sinai in New York City, told Fox News Digital.
“We wouldn’t accept that for a medication or a medical device, and we shouldn’t accept it for a product that tens of millions of people are using to make health decisions.”
Emergency scenarios
The team created 60 clinical scenarios across 21 medical specialties, ranging from minor conditions to true medical emergencies.
Three independent physicians then assigned an appropriate level of urgency for each case, based on published clinical practice guidelines in 56 medical societies.
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The researchers conducted 960 interactions with ChatGPT Health to see how the tool responded, taking into account gender, race, barriers to care and “social dynamics.”
While “clear-cut emergencies” — such as stroke or severe allergy — were generally handled well, the researchers found that the tool “under-triaged” many urgent medical issues.
The team created 60 clinical scenarios across 21 medical specialties, ranging from minor conditions to true medical emergencies. (iStock)
For example, in one asthma scenario, the system acknowledged that the patient was showing early signs of respiratory failure — but still recommended waiting instead of seeking emergency care.
“ChatGPT Health performs well in medium-severity cases, but fails at both ends of the spectrum — the cases where getting it right matters most,” Ramaswamy told Fox News Digital. “It under-triaged over half of genuine emergencies and over-triaged roughly two-thirds of mild cases that clinical guidelines say should be managed at home.”
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Under-triage can be life-threatening, the doctor noted, while over-triage can overwhelm emergency departments and delay care for those in real need.
Researchers also identified inconsistencies in suicide risk alerts. In some cases, it directed users to the 988 Suicide and Crisis Lifeline in lower-risk scenarios, and in others, it failed to offer that recommendation even when a person discussed suicidal ideations.
“ChatGPT Health performs well in medium-severity cases, but fails at both ends of the spectrum.”
“The suicide guardrail failure was the most alarming,” study co-author Girish N. Nadkarni, M.D., chief AI officer of the Mount Sinai Health System, told Fox News Digital.
ChatGPT Health is designed to show a crisis intervention banner when someone describes thoughts of self-harm, the researcher noted.
OpenAI launched ChatGPT Health, the medical-focused version of the popular chatbot tool, in January 2026. (Gabby Jones/Bloomberg via Getty Images)
“We tested it with a 27-year-old patient who said he’d been thinking about taking a lot of pills,” Nadkarni said. “When he described his symptoms alone, the banner appeared 100% of the time. Then we added normal lab results — same patient, same words, same severity — and the banner vanished.”
“A safety feature that works perfectly in one context and completely fails in a nearly identical context … is a fundamental safety problem.”
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The researchers were also surprised by the social influence aspect.
“When a family member in the scenario said ‘it’s nothing serious’ — which happens all the time in real life — the system became nearly 12 times more likely to downplay the patient’s symptoms,” Nadkarni said. “Everyone has a spouse or parent who tells them they’re overreacting. The AI shouldn’t be agreeing with them during a potential emergency.”
Fox News Digital reached out to Open AI, creator of ChatGPT, requesting comment.
Physicians react
Dr. Marc Siegel, Fox News senior medical analyst, called the new study “important.”
“It underlines the principle that while large language models can triage clear-cut emergencies, they have much more trouble with nuanced situations,” Siegel, who was not involved in the study, told Fox News Digital.
ChatGPT and other LLMs can be helpful tools, a doctor said, but they “should not be used to give medical direction.” (iStock)
“This is where doctors and clinical judgment come in — knowing the nuances of a patient’s history and how they report symptoms and their approach to health.”
ChatGPT and other LLMs can be helpful tools, Siegel said, but they “should not be used to give medical direction.”
“Machine learning and continued input of data can help, but will never compensate for the essential problem – human judgment is needed to decide whether something is a true emergency or not.”
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Dr. Harvey Castro, an emergency physician and AI expert in Texas, echoed the importance of the study, calling it “exactly the kind of independent safety evaluation we need.”
“Innovation moves fast. Oversight has to move just as fast,” Castro, who also did not work on the study, told Fox News Digital. “In healthcare, the most dangerous mistakes happen at the extremes, when something looks mild but is actually catastrophic. That’s where clinical judgment matters most, and where AI must be stress-tested.”
Study limitations
The researchers acknowledged some potential limitations in the study design.
“We used physician-written clinical scenarios rather than real patient conversations, and we tested at a single point in time — these systems update frequently, so performance may change,” Ramaswamy told Fox News Digital.
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Additionally, most of the missed emergencies happened in situations where the danger depended on how the condition was changing over time. It’s not clear whether the same problem would happen with acute medical emergencies.
Because the system had to choose just one fixed urgency category, the test may not reflect the more nuanced advice it might give in a back-and-forth conversation, the researchers noted.
ChatGPT Health is designed to show a crisis intervention banner when someone describes thoughts of self-harm. (iStock)
Also, the study wasn’t large enough to confidently detect small differences in how recommendations might vary by race or gender.
“We need continuous auditing, not one-time studies,” Castro noted. “These systems update frequently, so evaluation must be ongoing.”
‘Don’t wait’
The researchers emphasized the importance of seeking immediate care for serious issues.
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“If something feels seriously wrong — chest pain, difficulty breathing, a severe allergic reaction, thoughts of self-harm — go to the emergency department or call 988,” Ramaswamy advised. “Don’t wait for an AI to tell you it’s OK.”
The researchers noted that they support the use of AI to improve healthcare access, and that they didn’t conduct the study to “tear down the technology.”
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“These tools can be genuinely useful for the right things — understanding a diagnosis you’ve already received, looking up what your medications do and their side effects, or getting answers to questions that didn’t get fully addressed in a short doctor’s visit,” Ramaswamy said.
“That’s a very different use case from deciding whether you need emergency care. Treat them as a complement to your doctor, not a replacement.”
“This study doesn’t mean we abandon AI in healthcare.”
Castro agreed that the benefits of AI health tools should be weighed against the risks.
“AI health tools can increase access, reduce unnecessary visits and empower patients with information,” he said. “They are not inherently unsafe, but they are not yet substitutes for clinical judgment.”
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“This study doesn’t mean we abandon AI in healthcare,” he went on. “It means we mature it. Independent testing and stronger guardrails will determine whether AI becomes a safety net or a liability.”
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