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Smoking shrinks the brain and drives up Alzheimer’s risk, new study finds

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Smoking shrinks the brain and drives up Alzheimer’s risk, new study finds

Smoking is notorious for causing damage to the lungs — but a recent study confirmed that it’s also harmful to the brain.

Researchers from the Washington University School of Medicine (WashUMed) in St. Louis, Missouri, analyzed the brain scans, smoking history and genetic risk of 32,094 participants of European descent from the UK Biobank database.

Those who smoked one pack daily were found to have decreased brain volume compared to those who never smoked or had smoked fewer than 100 total cigarettes. 

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With each additional year of smoking, the shrinkage was greater.

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The study, published in the January 2024 issue of Biological Psychiatry: Global Open Science, helps to explain why older people who smoke are at a higher risk of Alzheimer’s disease and other dementias, according to the researchers.

Smoking is notorious for causing damage to the lungs, but recent research confirmed that it is also harmful to the brain. (iStock)

“People who smoke are more likely to have deterioration in gray and white matter, which provides a possible explanation as to why 14% of global Alzheimer’s disease cases could be attributable to cigarette smoking,” they wrote in the study findings.

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“Up until recently, scientists overlooked the effects of smoking on the brain, in part because we were focused on all the terrible effects of smoking on the lungs and the heart,” said senior author Laura J. Bierut, M.D., the Alumni Endowed Professor of Psychiatry, in a press release from WashUMed.

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“But as we’ve started looking at the brain more closely, it’s become apparent that smoking is also really bad for your brain.”

Those who smoked one pack daily were found to have decreased brain volume compared to those who never smoked or had smoked fewer than 100 total cigarettes.  (iStock)

It has long been known that aging is linked to a gradual reduction in brain volume, and this study shows that smoking speeds up that process, the researchers noted.

“This is important as our population gets older, because aging and smoking are both risk factors for dementia,” noted Bierut.

“There’s one thing you can change to stop aging your brain and putting yourself at increased risk of dementia, and that’s to quit smoking.”

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One positive finding was that kicking the habit can prevent the loss of additional brain tissue — but the shrinkage can’t be reversed.

“You can’t undo the damage that has already been done, but you can avoid causing further damage,” said first author Yoonhoo Chang, a graduate student at WashUMed.

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“Smoking is a modifiable risk factor. There’s one thing you can change to stop aging your brain and putting yourself at increased risk of dementia, and that’s to quit smoking.”

Fox News Digital reached out to the study authors for additional comment.

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Impact of toxins on aging

Dr. Brett Osborn, neurosurgery section chief at St. Mary’s Medical Center in West Palm Beach, Florida, was not involved in the WashUMed study but shared his reaction to the findings.

While aging — and some age-related diseases — can’t be prevented, Osborn noted that our lifestyle choices can accelerate or decelerate the process.

Dr. Brett Osborn, neurosurgery section chief at St. Mary’s Medical Center in West Palm Beach, Florida, shared his reaction to the study findings. (Dr. Brett Osborn)

“We can age gracefully in part by choosing to avoid toxins such as alcohol and smoking, both of which increase the production of toxic free radicals, also known as oxidative stress,” he told Fox News Digital.

When someone smokes, the doctor explained, the person’s blood vessel linings are “bombarded” by free radicals, which are electrons that cause cell damage. That impacts not only the heart and lungs, but also the brain.

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“When you smoke, the brain takes a hit due to the induced vascular damage,” Osborn said. “Over time, the brain shrinks, and this is evident on MRI.”

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The new study confirms not only the correlation between reduced global brain volume, but also causation, said Osborn. 

“It is not that those with reduced global brain volume tend to smoke from a genetic standpoint, but it is that those who smoke cause their brains to atrophy,” he said. 

“Smoking does terrible things not only to the body but also to the brain, and in some parts, disproportionately more than others.”

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“Smoking does terrible things not only to the body but also to the brain, and in some parts, disproportionately more than others,” a neurologist told Fox News Digital. (iStock)

The regions most affected by smoking are the frontal cortex (involved in executive function, memory input and mood), cerebellum (coordination), corpus callosum (information bridge between the two hemispheres), and amygdala (emotional response and memory), Osborn pointed out. 

“It is also well-established that hippocampal volume, or the volume of our primary center, is reduced in daily smokers,” he said. “It should be no surprise, therefore, that there is an increased incidence of Alzheimer’s disease in smokers.”

“Smoking does terrible things not only to the body but also to the brain.”

While other organs, such as the lungs, can recover after a person quits smoking, there are no subsequent increases in brain volume, said Osborn.

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“The brain demonstrates a lower capacity for recovery, so the best you can hope for is a deceleration in induced damage when you stop,” he said. “So, the sooner you quit, the better.”

The study helps to explain why older people who smoke are at a higher risk of Alzheimer’s disease and other dementias, according to the researchers. (REUTERS/Brian Snyder/File Photo)

“Remember, staying healthy lifelong is about making the right choices to mitigate the cellular damage that is the hallmark of the disease we call aging, to which no one is immune,” Osborn added. 

“Do everything in your power to slow it down, rather than accelerating the process by smoking.”

One out of every five U.S. deaths can be attributed to smoking, per the Centers for Disease Control and Prevention (CDC).

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Tips for kicking the habit

Dr. David Seitz, a New York-based physician with a specialty in addiction medicine, previously shared with Fox News Digital some tips for kicking the habit.

The first step is to remove all traces of cigarettes and other forms of smoking.

It’s also important to have a strong support system in place, the doctor said.

Some people find that it’s easier to gradually wean themselves off smoking instead of quitting cold turkey. (iStock)

He also suggested seeking out healthier activities to fill the gap, such as walking or jogging, listening to a relaxing playlist, meditating or going to a yoga class.

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Some people find that it’s easier to gradually wean themselves off smoking instead of quitting cold turkey.

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“This could involve gradually reducing the number of cigarettes smoked each day until eventually giving up completely, cutting back to a certain number of cigarettes per week or focusing on specific dates when you need to be completely smoke-free,” Seitz said.

For those who are unable to stop smoking on their own, Seitz recommended seeing a doctor for assistance.

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“Your doctor can provide helpful information about how to quit smoking, prescribe medications that may help, and also monitor your progress along the way.”

For more Health articles, visit www.foxnews.com/health.

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Seniors over 80 who eat specific diet may be less likely to reach 100 years old

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Seniors over 80 who eat specific diet may be less likely to reach 100 years old

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Older adults who avoid meat in their golden years may be less likely to reach age 100 than their meat-eating counterparts, new research suggests.

Researchers tracked more than 5,000 adults aged 80 or older who were enrolled in the Chinese Longitudinal Healthy Longevity Survey.

Between 1998 and 2018, data showed that those who did not eat meat were less likely to reach their 100th birthday than those who consumed animal products regularly.

The findings seem to contradict previous studies that have linked vegetarianism and plant-based diets to lower risks of heart disease, stroke, diabetes and obesity.

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Most evidence supporting the benefits of plant-based diets comes from studies tracking younger populations, the researchers noted. 

The findings contrast with previous research praising plant-based diets for their positive influence on heart health. (iStock)

The study, published in The American Journal of Clinical Nutrition, points to losses in muscle mass and bone density with age, shifts that can increase the risk of malnutrition and frailty in the “oldest old.”

As people enter their 80s and 90s, the nutritional priority often shifts from preventing long-term chronic diseases to maintaining day-to-day physical function, experts say.

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“The headline ‘vegetarians over 80 less likely to reach 100’ sounds surprising, because it contrasts with decades of data linking plant‑forward diets to lower chronic disease risk earlier in life,” Erin Palinski-Wade, a New Jersey-based registered dietitian, told Fox News Digital. 

“However, once you see that this research is limited to adults over the age of 80 who are also underweight — and that this link disappears with the consumption of eggs, dairy and fish — the results are less surprising.”

While diets earlier in life tend to emphasize avoiding long-term disease, older age necessitates nutrients and weight maintenance, experts say. (iStock)

In those over 80, restricting animal proteins may be less likely to promote longevity, according to Palinski-Wade, who was not involved in the study.

Eliminating all animal protein — particularly in a population that may already experience diminished hunger cues — can make it more difficult to meet adequate protein needs, potentially increasing the risk of nutrient deficiencies, the nutritionist said.

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In addition to a higher tendency to be underweight, older populations also face a greater risk of bone fractures due to lower calcium and protein intake.

Potential limitations

The lower rate of vegetarians reaching 100 was only observed in participants identified as underweight, the researchers noted. No such association was found in people who maintained a healthy weight.

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Because being underweight is already linked to greater frailty and mortality risk, the researchers noted that body weight may partly explain the findings, making it difficult to determine whether diet itself played a direct role.

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Those incorporating animal-sourced products other than meat were just as likely to live to 100. (iStock)

Additionally, the shortened lifespans were not found in people who continued to eat non-meat animal products, such as fish, dairy and eggs. 

Older adults with these more flexible diets were just as likely to live to 100 as those eating meat, as these foods may provide the nutrients necessary for maintaining muscle and bone health, the researchers noted.

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“This is an observational study, so it can only show associations, and does not prove that avoiding meat directly reduces the odds of reaching 100,” Palinski-Wade added.

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The researchers suggested that including small amounts of animal-sourced foods could help older seniors maintain essential nutrients and avoid the muscle loss often seen in those who stick strictly to plants.

Eliminating all animal protein — particularly in a population that may already experience diminished hunger cues — can make it more difficult to meet adequate protein needs, potentially increasing the risk of nutrient deficiencies. (iStock)

Palinski-Wade offered some guidance for those looking to optimize nutrition later in life.

“For adults in their 80s and beyond, especially anyone losing weight or muscle, the priority should be maintaining a healthy weight and meeting protein and micronutrient needs — even if that means adding or increasing fish, eggs, dairy or well‑planned, fortified plant proteins and supplements.”

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Strict vegan or very low‑protein patterns at that age should be carefully monitored by a dietitian or clinician, with attention to B12, vitamin D, calcium and total protein, according to Palinski-Wade.

“Younger and healthier adults can still confidently use plant‑forward or vegetarian patterns to lower long‑term chronic disease risk,” she added.

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The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s

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The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s


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Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

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Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

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In a dramatic turn of events that’s captured the attention of animal lovers worldwide, Punch — the young macaque at a zoo in Japan famous for his inseparable bond with a stuffed orangutan toy — has reached a major milestone in his journey toward social integration.

On Thursday, visitors and staff at the Ichikawa Zoological and Botanical Garden witnessed a breakthrough: Punch was seen cuddling with and hitching a ride on the back of a fellow macaque.

Punch’s story began with hardship. He was abandoned by his mother shortly after his birth in July 2025 — and to ensure his survival, zookeepers stepped in to hand-rear the primate.

On Jan. 19, 2026, the zoo officially began the process of reintegrating Punch into the “monkey mountain” enclosure.

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The transition was initially fraught with tension. 

Punch’s story began with hardship when he was abandoned by his mother shortly after he was born. To help him, zookeepers gave him a stuffed toy that he began dragging around everywhere he went.  (David Mareuil/Anadolu via Getty Images)

As a hand-reared infant, Punch was bullied and ignored by the established group of monkeys.

He was often seen huddled alone with his orange plush companion while the rest of the troop interacted.

BABY MONKEY CARRIES FAITHFUL STUFFED COMPANION EVERYWHERE HE GOES, DRAWING CROWDS AT ZOO

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In an official statement released Feb. 27, the Ichikawa Zoological and Botanical Garden detailed the meticulous care behind this process.

Previous viral videos showed Punch bullied by the rest of the troop, running to his plushy toy for comfort. (David Mareuil/Anadolu via Getty Images)

“From an animal welfare perspective, our primary goal is to reintegrate Punch with the troop,” the zoo said. 

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The strategy involved nursing Punch within the enclosure, so the troop could recognize him as one of their own, and pairing him with a gentle young female macaque prior to his full release to build his confidence.

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The latest footage, captured by X user @tate_gf, suggested the zoo’s patience is paying off. 

The video shows Punch seeking physical contact not from his toy, but from another monkey — eventually climbing onto its back for a vital social behavior for young macaques: the “piggyback ride.”

The zoo’s strategy appears to be paying off: Punch, shown at far left, was recently seen riding on the back of a fellow macaque. (David Mareuil/Anadolu via Getty Images)

While Punch still carries his stuffed toy for comfort during moments of perceived danger, the zoo remains optimistic about his progress. 

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The organization cited the successful 2009 case of Otome, another hand-reared macaque who eventually outgrew her stuffed toy, successfully integrated — and went on to raise four offspring of her own.

The zoo has had crowds coming to see Punch, with hundreds of people lining up to get inside to see the young star, according to reports. 

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“I’m hoping Punch has a good life like everybody else does, and think he’s a cute little guy,” one person commented online. 

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“Such a precious baby,” another person wrote. 

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