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Simple daily habit may help ease depression more than medication, researchers say

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Simple daily habit may help ease depression more than medication, researchers say

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A new study suggests that exercise can treat depression just as effectively as therapy and antidepressants.

A Cochrane review looked at 73 randomized controlled trials involving nearly 5,000 adults with a depression diagnosis. The studies compared exercise with either other active treatments — such as therapy or medication — or with “inactive interventions,” like being placed on a wait list or in a control group.

The London-based team discovered that exercise may be “moderately effective” compared to no therapy in reducing depression symptoms, according to a press release.

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EXERCISE AFFECTS THE HEART IN A HIDDEN, POWERFUL WAY BY REWIRING NERVES, STUDY FINDS

“There is probably little to no difference in depressive symptoms between people undertaking exercise and those receiving psychological therapy,” the authors noted in a study discussion on Cochrane’s website, and “there may be little to no difference in depressive symptoms between people doing exercise and those taking antidepressants.”

The analysis discovered that exercise may be “moderately effective” compared to no therapy in reducing depression symptoms. (iStock)

The review found that light- to moderate-intensity exercise was more beneficial for easing depression symptoms than vigorous exercise.

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No single type of physical activity stood out as the best, but mixed programs that included resistance training appeared to be “more effective” than just aerobic exercise. 

Some forms of exercise, like yoga and stretching, were not included in the analysis, but are areas to be further researched, the review noted.

Mixed exercise programs and resistance training appeared to be “more effective” in easing depression symptoms than just aerobic exercise. (iStock)

Professor Andrew Clegg, lead author of the review, wrote in a statement that exercise “appears to be a safe and accessible option for helping to manage symptoms of depression.”

“This suggests that exercise works well for some people, but not for everyone, and finding approaches that individuals are willing and able to maintain is important,” he said.

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Study limitations and risks

The researchers noted that there was a high risk of bias in some of the studies included in the review, and noted that the long-term effects of exercise on depression symptoms remain uncertain.

COMMON SPICE MAY BEAT DEPRESSION AND BOOST SEXUAL HEALTH, DOCTOR SAYS

Clegg noted that “larger, high-quality studies” are needed to determine which types of exercise work best and whether the benefits last over time.

The comparison between exercise and other treatments and how they benefit people’s quality of life were also “inconsistent and uncertain.”

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“Adverse events from exercise were not common,” the researchers mentioned. “The small number of participants who experienced them usually reported muscle and joint problems or worsening of depression.”

About 21 million U.S. adults had at least one major depressive episode in a recent year — equivalent to roughly 8.3% of all U.S. adults, according to the National Institutes of Health. (iStock)

“Future research should focus on improving the quality of the studies, working out which characteristics of exercise are effective for different people, and ensuring different types of people are included in the studies so that health equity issues can be considered,” they went on.

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About 21 million U.S. adults had at least one major depressive episode in a recent year — equivalent to roughly 8.3% of all U.S. adults, according to the National Institute of Mental Health.

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Depression symptoms include feelings of sadness, hopelessness, anxiety, guilt or irritability, as well as loss of interest or pleasure in hobbies and activities. Fatigue, poor concentration, sleep disturbances, appetite changes and social withdrawal are also red flags, in addition to thoughts about dying or suicidal ideations. 

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The condition is most often treated by antidepressant medications and psychological therapies, such as talk therapy. Anyone who needs help should consult their doctor.

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.

That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.

The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.

LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS

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Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).

Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.

The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.

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“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”

Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.

HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS

In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.

For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)

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The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.

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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”

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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.

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Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)

“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.

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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.

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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs


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What Is Zepbound? Weight-Loss Benefits, Costs and Dosage




















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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION

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Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

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The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

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New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities. 

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment. 

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

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