Health
New cervical cancer treatment approach could reduce risk of death by 40%, trial results show
There could be new hope on the horizon for women fighting cervical cancer.
Researchers investigated a new approach to treating the disease in a study funded by Cancer Research UK.
In a phase 3 trial, patients went through a short, six-week course of chemotherapy before starting standard chemoradiation (CRT) treatment.
CERVICAL CANCER DEATHS COULD BE REDUCED WITH HOME HPV TESTING, STUDY FINDS
This approach was found to slash death risk by 40%, and it also reduced the likelihood of the disease returning or relapsing by 35%.
There are about 11,500 new cervical cancer diagnoses in the U.S. each year and about 4,000 women die from the disease, according to the CDC. (iStock)
After five years, 80% of trial participants who received the induction chemo session followed by CRT survived, and 73% reported that their cancer had not returned or spread.
Dr. Mary McCormack, PhD, one of the trial researchers, shared with Fox News Digital that this method led to an 8% absolute improvement in survival rates at five years.
CERVICAL CANCER DRUG RAISES SURVIVAL RATE BY 30% COMPARED TO CHEMOTHERAPY: ‘GAME-CHANGER’
Over the team’s decade-long research, McCormack noted that there have been some changes in standard radiation delivery.
“As this was a randomized trial, these changes, which were incorporated into the study, were taken into account and affected both arms of the trial equally,” she said.
After five years, 80% of trial participants who received the induction chemo followed by CRT survived by the five-year mark. (iStock)
Based on these findings, McCormack encouraged clinicians to offer an additional short course of chemo to their patients.
“These drugs are widely available,” she said. “The trial results should be incorporated into national and international guidelines within the next few months.”
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Dr. Brian Slomovitz, director of gynecologic oncology and co-chair of the Cancer Research Committee at Mount Sinai Medical Center in Florida, called these results “very compelling.”
“They demonstrate a significant overall survival and progression-free survival advantage in patients who suffer from this disease,” he told Fox News Digital.
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The doctor did note a few limitations, however, including that the trial was not done in a “United States-like setting.”
Based on these findings, the researchers encourage clinicians to offer an additional short course of chemo to their patients. (iStock)
“This may have led to under-performance of the control arm,” Slomovitz said. “Also, radiation techniques and the availability of therapies after progression (especially immunotherapy) have improved since this trial.”
“I am really not sure whether it’s applicable for patients in the U.S.,” he continued. “I look forward to future studies to hopefully confirm these results.”
There are about 11,500 new cervical cancer diagnoses in the U.S. each year and about 4,000 women die from the disease, according to the Centers for Disease Control and Prevention (CDC).
To prevent cervical cancer, experts recommend getting vaccinated against types of HPV (human papillomavirus) that can cause it.
The CDC also recommends that women get routine Pap smears and HPV screenings.
Health
The Best Weight Loss Medications and Supplements in 2026
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Health
Nutrition experts react to new food pyramid, and more of this week’s biggest health stories
NEWYou can now listen to Fox News articles!
Top stories
→ Health experts react to the Trump administration’s newly revamped food pyramid
→ Deadly superbug spreads across US as drug resistance grows
→ Common pain relievers may raise heart disease and stroke risk, doctors warn
The Trump administration announced on Wednesday the 2025-2030 Dietary Guidelines for Americans, putting “real food” back at the center of health. (Chance Yeh/Getty Images for HubSpot; iStock)
On the lookout
→ Flu cases spiked in New York State again this week, sparking warnings from health officials
→ Not all cancers should be treated right away, medical experts say
Conversation starters
→ The shape of your butt is an indicator of key health risks — what does yours say about you?
→ Trending “analog bags” are being touted as replacements for smartphones
Healthy living
→ Experimental vaccine could save thousands of lives per year, scientist claims
→ Little-known prescription pill is helping Americans drink less alcohol
Quote of the week
“This is a big deal.”
→ Elon Musk announced that Neuralink — the brain implant chip that allows users to communicate using their minds — will start “high-volume” production this year, calling the step a “big deal”
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Health
‘Weight Loss Has Never Been About Calories’: How This Low-Insulin Diet Helped Lillie, 58, Drop 70 Lbs!
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