Health
Higher stroke risk linked to consuming certain amount of alcohol, study finds
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A new study suggests that pouring a third drink could mean trouble for your brain.
Harvard researchers have found that people who drink three or more alcoholic drinks a day may suffer a stroke more than a decade earlier than people who drink less.
The research, published this week in Neurology, the medical journal of the American Academy of Neurology, links heavy drinking to not just earlier strokes, but also larger, deadlier brain bleeds and long-term brain damage.
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The study analyzed data from 1,600 adults averaging 75 years of age who were hospitalized for intracerebral hemorrhage, a type of stroke caused by bleeding inside the brain.
During their hospital stays, participants were asked about their drinking habits, either directly or through family members.
Harvard researchers have found that people who drink three or more alcoholic drinks a day may suffer a stroke more than a decade earlier than people who drink less. (iStock)
Of the 1,600 participants, about 7% were classified as heavy drinkers.
The researchers defined heavy drinking as having three or more drinks daily, where one drink equals a 12-ounce beer, a 5-ounce glass of wine or a 1.5-ounce shot of liquor.
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Brain scans revealed the severity of the bleeds and whether patients showed signs of cerebral small vessel disease, a condition that damages tiny blood vessels in the brain and is linked to aging, high blood pressure and dementia.
Heavy drinkers experienced brain bleeds at an average age of 64, compared to 75 for non-heavy drinkers, an 11-year gap. Their brain bleeds were also 70% larger on average.
Researchers defined “heavy drinking” as having three or more drinks daily, where one drink equals a 12-ounce beer, a 5-ounce glass of wine or a 1.5-ounce shot of liquor. (Getty Images)
Heavy drinkers were also twice as likely to have bleeding deep in the brain and nearly twice as likely to have bleeding that spread into the brain’s fluid-filled spaces, a serious complication called intraventricular extension, the study found.
Additionally, they were three times more likely to have severe white matter damage, which is linked to long-term cognitive decline and brain aging.
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While alcohol has previously been tied to stroke risk, this research shows it may also accelerate small vessel disease, making the brain more vulnerable to severe strokes and slower recovery, according to lead author Dr. M. Edip Gurol of Harvard University.
“Reducing heavy alcohol use may not only lower a person’s risk of bleeding stroke, but it may also slow the progression of cerebral small vessel disease, which in turn may reduce the chances of having another stroke, cognitive decline and long-term disability,” Gurol said in a press release.
“Heavier drinking is also associated with high blood pressure, which is a contributing factor for this type of stroke.”
Jennifer Tujague, chief scientist at the International Alliance for Responsible Drinking (IARD) in Washington, D.C., was not involved in the study but shared her reaction with Fox News Digital.
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“These results appear to be consistent with previous epidemiological studies that have found an increased risk of hemorrhagic stroke associated with heavier drinking levels,” she said.
“Heavier drinking is also associated with high blood pressure, which is a contributing factor for this type of stroke.”
Heavy drinkers in the study had brain bleeds that were 70% larger than those in non-heavy drinkers, researchers found. (iStock)
There were some limitations to the study, the authors noted, including that it was a cross-sectional study design, which means it looked at data from a single point in time rather than following people over a longer period.
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Due to that, researchers can’t say for sure whether drinking caused the strokes or just made them worse.
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Alcohol use was also self-reported, meaning people might have underestimated or overestimated how much they drank. Lifetime drinking habits also weren’t available.
Fox News Digital reached out to the Distilled Spirits Council for comment.
Health
Dementia risk signals could lie in simple blood pressure readings, researchers say
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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.
That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.
The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.
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Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).
Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.
The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”
Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.
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In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.
For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)
The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.
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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”
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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.
Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)
“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.
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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.
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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.
Health
Everything You Need To Know About Zepbound for Weight Loss, Including Costs
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Health
‘Gas station heroin’ banned in another state amid nationwide crackdowns
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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.
Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.
Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.
HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION
Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.
Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.
Tianeptine can be more potent than morphine and addictive opioids. (iStock)
Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.
Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.
The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.
Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)
Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.
“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.
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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.
Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”
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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”
New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.
“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)
“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”
Schwaner said he believes the substance requires national regulation due to its addictive qualities.
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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.
Fox News Digital reached out to the FDA for comment.
Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.
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