Health
Cure for men's hair loss could be found in sugar stored in the body, study suggests
The cure for male pattern baldness could already be in the human body.
The condition, which causes gradual hair loss, affects up to 50% of men worldwide.
Researchers at the University of Sheffield in the U.K. claim the fix might be found in a sugar that’s naturally present in the human body.
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The study, published in the journal Frontiers in Pharmacology, revealed that this sugar, known as 2-deoxy-D-ribose (2dDR), is involved in various biological processes in animals and humans and can stimulate hair regrowth in mice.
Scientists from U.K.’s Sheffield and COMSATS University Pakistan have studied the sugar for the past eight years, focusing on its ability to help heal wounds by forming new blood vessels.
Male pattern baldness affects up to 50% of men worldwide, according to the University of Sheffield. (iStock)
The researchers noticed that hair around the wounds also appeared to grow more quickly compared to untreated wounds.
The scientists then tested this on testosterone-driven hair loss in mice, which is similar to the cause of male pattern baldness, according to a university press release.
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When they applied just a small dose of the sugar, new blood vessels were formed, leading to hair regrowth.
The findings suggest that the deoxy ribose sugar could be as effective as hair regrowth drugs, according to the university.
Researchers reported that a small dose of deoxy ribose sugar led to hair regrowth in mice. (iStock)
Sheila MacNeil, PhD, emeritus professor of tissue engineering at the University of Sheffield, noted that male pattern baldness could benefit from more research.
“There are only two FDA-approved drugs for this condition at present,” she wrote in a statement sent to Fox News Digital.
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“Our U.K./Pakistan collaboration unexpectedly turned up a small, naturally occurring sugar that stimulates new blood vessel formation, and we were delighted to discover that it not only stimulates wound healing, but [also] stimulates hair growth in an animal model.”
The sugar is “natural, inexpensive and stable,” MacNeill noted, and can be delivered in an “easy to apply gel,” which the researchers plan to explore in further research.
The sugar could be produced as a hair gel, the study researcher (not pictured) suggested. (iStock)
Dr. John Whyte, WebMD’s chief medical officer in Washington, D.C., called the study findings “intriguing” in a conversation with Fox News Digital.
“This naturally occurring sugar’s effectiveness indicates significant potential in developing new hair loss treatments,” said Whyte, who was not involved in the research.
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Current therapies “have been around for a while, have limited effectiveness and can have side effects,” the doctor noted.
Given that this research is still in the early stages, further investigation and clinical trials will be necessary to determine whether the sugar can be “safely and effectively developed into a viable cure for male pattern baldness,” Whyte added.
“More research is required before it can be considered a cure,” one doctor told Fox News Digital. (iStock)
“The public should view these results with cautious optimism,” he went on.
“The study provides hope for new natural treatments for hair loss, but more research is required before it can be considered a cure.”
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Dermatologist Brendan Camp, M.D., in New York, also reacted to the findings, reiterating to Fox News Digital that there are limited treatments available for hair loss.
“The study provides hope for new natural treatments for hair loss, but more research is required before it can be considered a cure.”
“A number of potential treatments have been studied, but none have been found to be curative,” said Camp, who was not involved in the research.
“The current goal of treatment of alopecia is to help patients retain the hair they have.”
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This study could ultimately lead to a new, effective therapy if future research is successful, he said.
“The treatment in question, 2-deoxy-D-ribose (2dDR), is thought to improve hair growth by causing an increase in the number of blood vessels,” he said.
There is currently no cure for alopecia, a dermatologist noted. (iStock)
“While potentially effective at encouraging existing hair follicles to grow, it seems unlikely that it will make follicles that have already disappeared grow back.”
He added, “While promising, this treatment requires additional studies to confirm the reproducibility, efficacy and real-world application of 2-deoxy-D-ribose (2dDR) as a treatment for alopecia.”
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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.
By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.
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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.
“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)
While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.
Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.
“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”
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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.
The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.
Clinical treatments remain identical for both primary strains of the flu virus. (iStock)
During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.
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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.
Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.
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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.
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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”
This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)
“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”
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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.
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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.
Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.
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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.
While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.
To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years.
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The study group included 131,426 men and 318,686 women, according to the study’s press release.
During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.
For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)
Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.
The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.
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After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.
A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.
An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)
An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.
The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.
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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.
The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.
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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.
Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)
Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.
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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.
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The findings were published in the International Journal of Cancer.
Fox News Digital reached out to the researchers requesting comment.
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