Could At-Home Brain Stimulation Reduce Psychiatry’s Reliance on S.S.R.I.s?

“Our brains are so pharmaceutically inclined,” he said. “This fits into the model of pills.”

At the same time, tDCS could also challenge the current, pill-centric paradigm, by pushing psychiatrists to go beyond old notions of serotonin deficiencies and chemical imbalances, and to think more broadly about getting the brain unstuck. The two treatments together, research suggests may work together to nudge the brain toward a more plastic, activated state to help people overcome old patterns.

For instance, Dr. Somayya Kajee, a psychiatrist in Norwich, England, has found that tDCS helped some of her patients taper off an antidepressant or avoid having to start on another one. She added she has successfully used Flow to treat her neurodivergent patients who were taking medication for A.D.H.D. or autism, and who did not want to add on an S.S.R.I.

Ms. Davies started tDCS a few weeks after increasing her Prozac dosage. When she first put the headset on for 30 minutes, the recommended interval, she recalled feeling only a slight tingling — a “spicy sensation,” similar to having your hair bleached, as a participant in a clinical trial put it.

But within a few days, something shifted for Ms. Davies. She felt clearer, she said. The harsh voice in her head quieted. It was as if the world was in color again.

She said she could not say for sure what made the difference — the tDCS, delayed effects of the antidepressant, the passage of time or some combination — but “whatever it was helped to make me think, ‘Actually, maybe I can do this,’” she said. For the first time, she looked forward to giving her baby a bath.