Fitness
Why The Heart Exercise ‘Sweet Spot’ May Be 560 Minutes Weekly, Not 150
(Photo by Prostock-studio on Shutterstock)
The Standard Exercise Guideline Cuts Heart Risk by Only 8%, New Data Show
In A Nutshell
- Hitting the standard 150-minutes-per-week exercise guideline was associated with only about an 8% to 9% reduction in heart disease risk across all fitness levels, a reduction the researchers describe as “consistent but modest.”
- Cutting heart disease risk by 30% or more appeared to require exercise volumes roughly three to four times higher than the minimum recommendation, around 560 to 610 minutes of moderate-to-vigorous activity per week.
- A person’s cardiorespiratory fitness level independently contributed to lower heart disease risk beyond what exercise volume alone explained, with each additional unit of fitness linked to approximately 2% lower risk.
For decades, the exercise advice handed out in doctor’s offices, schools, and government health campaigns has told everyone to get at least 150 minutes of moderate activity per week, and your heart will thank you. Millions of Americans have taken that suggestion very seriously, treating it as a finish line of sorts. A new large-scale study suggests it may be closer to a starting block.
Published in the British Journal of Sports Medicine, the research tracked more than 17,000 adults over nearly eight years and found that hitting the standard 150-minute weekly target was associated with only about an 8% to 9% reduction in heart disease risk. To cut that risk by 30% or more, the data pointed to a much higher threshold: somewhere around 560 to 610 minutes of moderate-to-vigorous activity per week. That’s roughly an hour and a half of moderate-to-vigorous activity per day.
Beyond raw minutes, the study identified a second factor that most public health guidelines barely acknowledge: how physically fit a person already is. Even after accounting for how much someone exercised, people with higher cardiorespiratory fitness, basically how well the heart and lungs deliver oxygen during exertion, had meaningfully lower heart disease risk. Fitness, the data suggest, may also play an independent protective role that extra exercise time alone doesn’t fully replicate.
What the 150-Minute Guideline Actually Delivers
To understand what was measured, it helps to understand how it was measured. Researchers drew on data from the UK Biobank, a large British health research database that recruited around 500,000 adults between the ages of 40 and 69. For this study, the team focused on a subset of roughly 17,000 participants who wore a wrist-based motion sensor for seven consecutive days. That device-based measurement is a meaningful advantage over most prior research, which relied on people self-reporting their own exercise habits, a method well-known for overestimating actual activity levels.
Participants also completed a stationary bike test at enrollment, which allowed researchers to estimate each person’s cardiorespiratory fitness level. After filtering for those without prior heart disease and with complete data, 17,088 people made it into the final analysis.
Over a median follow-up of just under eight years, 1,233 of those participants experienced a cardiovascular event: irregular heart rhythms, heart attacks, heart failure, or stroke. Researchers used an advanced statistical model to map how different combinations of weekly exercise volume and fitness level related to those outcomes.
What emerged was a clear tiered picture. At the guideline level of 150 minutes per week, the risk reduction was described by the researchers as “consistent but modest,” coming in at roughly 8% to 9% across all fitness levels. To push that figure to 20%, participants needed approximately 340 to 370 minutes of moderate-to-vigorous activity per week, more than double the recommendation. Reaching a 30% reduction required jumping to roughly 560 to 610 minutes per week.

Why Fitness Matters Beyond Step Count
One of the more meaningful findings concerns what fitness itself adds to the equation, independent of how much someone moves. Using a statistical technique designed to isolate fitness’s effect from exercise behavior, the researchers found that each additional unit of fitness was associated with approximately 2% lower heart disease risk. The authors note this pattern is consistent with fitness carrying heart-protective effects through biological pathways, such as changes in heart structure and improved blood vessel function, that weekly exercise volume doesn’t fully capture.
Lower-fitness individuals also faced a steeper climb to reach the same risk reductions as their fitter counterparts. According to a table the researchers built to translate findings into practical targets, a person with low fitness needed roughly 30 to 50 more minutes per week than a high-fitness person to achieve the same percentage reduction in risk. Reaching a 20% risk reduction, for example, required approximately 370 minutes per week for lower-fitness individuals compared to approximately 340 minutes for those with higher fitness.
What a Genetic Analysis Added
Beyond tracking real-world behavior, the research team added a layer of genetic analysis to test whether the associations they found were likely to reflect true cause and effect, rather than the result of other lifestyle factors that active, fit people tend to share. This type of analysis uses inherited genetic differences between people as a kind of natural experiment.
The genetic findings offered partial support for the observational results. Genetically predicted higher fitness was most clearly linked to lower heart failure risk, with odds roughly 21% lower compared to those with genetically lower fitness levels. Evidence for other cardiovascular outcomes was less consistent, and the case for exercise behavior itself, as opposed to fitness as a physical trait, was weaker still across the genetic analysis.
The researchers explain this gap by noting that genetic tools are better suited to capturing stable biological traits like fitness than complex behaviors like weekly exercise habits. They conclude that the observational findings remain “the strongest available evidence for guiding activity-based prescriptions.”
Rethinking What Exercise Advice Should Do
The study’s authors propose that future guidelines may need to draw a clearer line between two distinct goals: the minimum exercise volume needed to avoid the worst cardiovascular outcomes, and the substantially higher volumes needed for substantial cardiovascular risk reduction. They also suggest that measuring a person’s fitness level, not just asking how much they exercise, could help doctors set more personalized targets.
About 11.6% of participants in the study, roughly 1,980 out of 17,088, managed to hit or exceed the 560-minute-per-week mark, confirming that such volumes are achievable but represent a high bar for most people. For those with low baseline fitness, the challenge is compounded: they face both higher absolute risk and the need to put in more work to see the same relative benefit.
The 150-minute guideline isn’t wrong. For the large share of Americans who don’t even hit that threshold yet, getting there still delivers real cardiovascular benefit. But for those who have cleared that mark and assumed they were done, this research makes a solid case that meaningful heart protection may require considerably more.
Disclaimer: This article is intended for general informational purposes only and does not constitute medical advice. The findings described are based on observational research and should not be used to self-diagnose, treat, or make changes to an exercise or health regimen without consulting a qualified healthcare provider. Individual health needs and risk factors vary. Speak with your doctor before significantly increasing your physical activity level.
Paper Notes
Limitations
Several important constraints apply to these findings. The UK Biobank cohort skews toward healthier, predominantly white, middle-aged to older adults living in the United Kingdom, which limits how well the results translate to younger people, non-white populations, or other countries. Physical activity was measured during only a single seven-day window, which may not reflect a person’s typical long-term habits. Fitness was estimated using a submaximal bike test rather than a gold-standard maximal effort test, introducing some measurement uncertainty, particularly for individuals with unusual heart rate responses to exercise. The study also measured exercise and fitness at a single point in time, so it can’t account for how those behaviors change over years. Despite the genetic analysis component, the observational design cannot fully rule out unmeasured lifestyle or health factors. The genetic instruments used in the analysis explained limited variation in physical activity behavior, and substantial heterogeneity was detected across genetic variants for several outcome pairs; the authors addressed this using random-effects models. Patients and members of the public were not involved in the study’s design or conduct.
Funding and Disclosures
The authors declared no specific grant funding from any public, commercial, or not-for-profit agency. No competing interests were declared. The study was conducted using the UK Biobank resource under Application Number 1050630 and was approved by the North West Multicentre Research Ethics Committee (reference 11/NW/0382).
Publication Details
Paper Title: Joint non-linear dose–response associations of device-measured physical activity and cardiorespiratory fitness with cardiovascular disease: a cohort and Mendelian randomisation study | Authors: Zhide Liang, Senyao Du, Shiao Zhao, Xianfei Wang, Qiang Yan, Baichao Xu, Sanfan Ng, Ziheng Ning | Journal: British Journal of Sports Medicine (BMJ Group) | DOI: 10.1136/bjsports-2025-111351 | Status: Published online ahead of print, accepted 6 April 2026
Fitness
Yes, Exercise Can Reverse Brain Aging. How Much Is Less Than You Might Think.
SCIENTISTS HAVE JUST given you one more reason not to skip your workout. Regular exercise could be turning back the age of your brain—by almost a year.
It didn’t take a lot of exercise, either. When people exercised for 150 minutes a week, their brains stayed younger. (If the number sounds familiar, it’s what multiple health organizations, including the CDC recommends for physical activity.) All they did was break their workouts into two 60-minute cardio sessions in the researchers’ lab, followed by a half-hour home workout.
When scientists reviewed the MRI brain scans before and after the year-long trial, they saw that the brains of the regular exercisers were 0.6 years younger than when they first started out. Researchers also looked at the brains of people who didn’t work out at all. Their brains were 0.35 years older. Put together, the difference in brain aging between both groups was nearly a year.
“These absolute changes were modest, but even a one-year shift in brain age could matter over the course of decades,” says Lu Wan, research neuroscience data scientist at the AdventHealth Research Institute and lead study author. Wan and her team unveiled the full results in the Journal of Sport and Health Science.
Considering the 130 people in the study were between 26 and 58, the findings suggest there’s still time to help your brain even if you’ve been sedentary for most of your life.
“Each additional ‘year’ of brain age is associated with meaningful differences in later-life health,” adds Kirk Erickson, PhD, director of translational neuroscience at AdventHealth Research Institute and senior author. “From a lifespan perspective, nudging the brain in a younger direction in midlife could be very important. If we can slow brain aging before major problems appear, we may be able to delay or reduce the risk of later-life cognitive decline and dementia.”
How Does Exercise Help Maintain a Younger Brain?
THE RESEARCHERS LOOKED at several potential pathways exercise might work through—changes in fitness, body composition, blood pressure, or potential changes in a protein called BDNF that helps promote the creation of new brain connections. While exercise improved people’s overall fitness, the team did not find that any of these measures could statistically explain the reversal in brain aging in this trial.
“That was a surprise,” Wan says. “We expected improvements in fitness or blood pressure to account for the effect, but they didn’t. Exercise may be acting through additional mechanisms we haven’t captured yet, such as subtle changes in brain structure, inflammation, vascular health or other molecular factors.”
Still, there’s no need to wait for scientists to figure out the mechanism. Taking action now—whether you’re in your 30s, 40s, and 50s can make a difference later in maintaining a youthful brain.
“People often ask, ‘Is there anything I can do now to protect my brain later?’” DR. Erickson says. “Our findings support the idea that following current exercise guidelines—150 minutes per week of moderate-to-vigorous aerobic activity—may help keep the brain biologically younger, even in midlife.”
Jocelyn Solis-Moreira, MS is the associate health & fitness for Men’s Health and has previously written for CNN, Scientific American, Popular Science, and National Geographic before joining the brand. When she’s not working, she’s doing circus arts or working towards the perfect pull-up.
Fitness
I Ran 5K Every Day for 28 Days – Here’s What it Did to My Body, My Fitness and My Strength
The challenge was simple: run 5k every day for 28 days. No rest days, no shortcuts, no doubling up to get ahead. Just 5k, every day, regardless of how I felt.
I wasn’t starting from scratch, but I wasn’t in peak running shape either. My training had been half-hearted for a while – enough to get by, but not really enough to improve. I knew 5k was doable on any given day. The question was what it would feel like doing it 28 times in a row, with a sleep-shy toddler, work and general life distractions thrown in. I also kept strength training twice a week throughout – mainly because I didn’t want my gym numbers to completely fall off a cliff.
The plan – if you can call it that – was to hold everything steady and see what gave first.
5K a Day
The first week felt like a chore more often than not. A couple of runs came straight after the post-work commute, when motivation was low and the run itself didn’t do much to improve things. One evening in the rain was particularly grim. Another came off the back of no sleep, was left until late and done purely because it had to be.
The gym treadmill made an appearance one lunch break, which was an immediate mistake. Five kilometres indoors felt far longer than it should, even when breaking it up with intervals just to stay engaged.
By the second week, fatigue started to build. Day nine stood out as the hardest – low energy, heavy legs and no real explanation beyond the fact that everything was adding up. It didn’t feel like I was getting fitter, just more tired.
Around the middle of the challenge, things became more manageable. The daily effort started to feel less like a battle and more like routine. By day 20, it was just part of the day.
Daily Habits
Our fitness director, Andrew Tracey, explains the rationale behind daily fitness challenges.
‘If you’re looking to make a habit really stick, to the point where it’s almost automatic, then daily adherence can remove a lot of decision fatigue and deliberation. A study in the European Journal of Social Psychology found that, on average, it takes 66 days to achieve automaticity with a habit, but that daily adherence accelerated this time greatly.
‘That being said, “daily workout challenges” tend to be found at the extremes: Facebook mums committing to 30 squats a day for a month (no shade, a great thing to do), or YouTube men documenting their weird new obsession (“You won’t believe what happened when I did this for 30 days…”). They also tend to veer from harmless, and usually fruitless, to ill-advised and self-destructive. But there’s a lot of evidence in favour of building daily habits – especially fitness ones – and the benefits these can have on the rest of your life.’
Progressive Overload
I wasn’t new to running, but if you are, heed this advice from Daine McKibben Rice, director of Validus Sports Injury Clinic.
‘Running 5k every day for 28 days is less about distance and more about load tolerance. For most people, 5k daily represents a pretty significant increase in cumulative load, particularly if they’re not already running regularly. The strongest evidence shows that rapid increases in training load are the primary driver of running-related injury, rather than distance alone.
‘For beginners, the risks are higher. Around one-third of recreational runners sustain injuries annually, with overuse injuries being the top of the list: such as tendinopathy, shin splints or patellofemoral pain. This can be due to repeated loading without sufficient conditioning or recovery, as musculoskeletal tissues take more time to adapt compared with cardiovascular fitness.
‘A gradual build-up is essential. For beginners, increasing running volume by 5% per week and progressing from two to three runs weekly towards consecutive running days is a safer approach than starting with daily 5k runs.’
The Verdict
By the final day, I wasn’t desperate for it to end, which felt like an achievement in itself. I finished with a 5k time trial and came within 30 seconds of the 20-minute mark – not an all-time PB, but the quickest of the year and better than expected given there hadn’t been a single rest day in four weeks.
The more interesting result was how quickly my body adjusted to running every day. Individual runs didn’t suddenly feel easy, but they stopped feeling like a big deal. It became normal to head out, get 5k done and move on.
The strength training was where things got confusing. I expected my numbers to dip, or at least stall, but the opposite happened. At the end of the challenge, I hit a two-rep squat PB. Which either says something about the benefits of consistent training or suggests I’d been underperforming before. Possibly both.
In body composition, not much changed. I didn’t lose muscle, but I didn’t drop any body fat either. That’s probably down to eating more to keep up with the extra running. Daily cardio on its own isn’t a guaranteed shortcut to getting leaner, especially if you’re fuelling properly. And to be fair, that wasn’t the point of the challenge anyway.
Running every day isn’t something I’d recommend in the long term and it’s not the smartest way to improve performance. But as a short, controlled block of consistency, it does exactly what you’d expect: it builds a habit, raises your baseline and proves you can handle more than you think.
Isaac Williams is Site Editor for both Women’s Health UK and Men’s Health UK, guiding and supporting the content teams to create content across all platforms. Isaac’s love of health and fitness began at Loughborough University, where he graduated with a History and English degree in 2014. His first job was at Men’s Running magazine, where he progressed from Staff Writer to Editor. Among his highlights of those four years include completing a 24-hour track race (never again), just about finishing a multi-day ultramarathon in the Azores, and chugging his way around a ‘beer mile’. Isaac ventured into the world of freelance journalism in 2018, interviewing some of the biggest names in sport – like Anthony Joshua and Ben Stokes – and writing features for the likes of The Guardian, Red Bull, ShortList and BBC Countryfile. He was also a regular contributor to an adventure series called ‘The Man Who’: speaking to some of the world’s most extreme explorers from the wilds of Caffè Nero. In late-2019, Isaac became Editor of Men’s Fitness UK. In his five years there, Isaac was responsible for editing the monthly magazine and managing website content, ultimately helping the brand transition to a ‘digital-first’ approach. He joined Hearst UK as Multiplatform Editor in December 2024, where he manages day-to-day digital output, edits content and writes articles on all things health and fitness. When he’s not hammering at his keyboard, Isaac enjoys exercise and trying – unsuccessfully, so far – to teach his baby son to kick a football. You can follow Isaac on Instagram @isaacw1993.
Fitness
Jennifer Aniston, 57, says she’s stronger now than in her 20s – and credits one simple training shift
Known for her disciplined approach to fitness, Jennifer Aniston has been using the Pvolve method for five years to build strength and mobility. Her trainer, Dani Coleman, recently shared the biggest changes she’s seen in Jennifer’s fitness since they started working together.
‘She has always been passionate about movement and wellness. But it has truly been game-changing to watch her strength year after year just get better and better, and to see her mentality shift with how she imagines what a successful workout is,’ she said on an episode of The Bossticks podcast.
Jennifer used to define a successful workout as one that was more traditionally intense. But she’s realised that ‘you don’t have to break your body down to get a good workout’, Dani revealed.
‘She’s talked about previous injuries she’s had and how she used to think that you needed gruelling workouts, even when she had a back injury. I think the most rewarding thing is really seeing her mindset shift.’
It’s therefore been especially gratifying ‘seeing Jennifer level up her weights and just trust me to put her through it now’.
Jennifer agrees.
‘Simpler is better – and consistency,’ she said in a recent Pvolve clip.
Pvolve founder Rachel Katzman also acknowledged that Jennifer now believes the best workouts build up and support her body, rather than punish it.
‘The one thing she always says is, “I wish I had this in my 20s,”’ Rachel said of Jennifer’s enthusiasm for Pvolve on another recent episode of The Bossticks.
‘“I wish I didn’t destroy my body when I was younger to look a certain way because that’s what I thought I had to do,”’ she continued. ‘And now with Pvolve, I look better than I did back then. I feel better. I’m stronger. I’m leaner. I just have more energy.’
Jennifer Anniston’s current Pvolve routine
Rachel confirmed key details about Jennifer’s workout schedule.
‘I heard a little rumour that she does Pvolve only four days a week,’ podcast host Lauryn said.
‘I think that rumour’s true,’ Rachel confirmed.
‘And she does an hour,’ continued Lauryn.
‘You can ask Dani for specifics, but yes,’ Rachel replied.
The founder also emphasised the importance of strength training and described her own changing attitude towards lifting weights.
‘I’m definitely going up in my weights. I was somebody who was very, very scared of weights. I didn’t even want to use a 2lb (0.9kg) weight. Now, I’ve got my 12lb (5.4kg) and my 15lb (6.8kg) weights.’
Echoing her, Dani’s main piece of advice for Jennifer – and trainees more generally – is still ‘to prioritise strength, as well as your mobility and stability’.
One of our most frequently asked questions here at Women’s Health? How to build muscle and burn fat at the same time. So, we asked superstar trainer Oyinda Okunowo exactly how to do it. In this 4-week plan – created exclusively for Women’s Health COLLECTIVE members – you’ll get the workouts and nutrition guidance needed to help you on your way to better body composition. Tap the link below to unlock 14 days of free access to Oyinda’s plan and start training today.
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