Research finds that people with obesity who exercise regularly show improved fat tissue health, which may lead to reduced risk of metabolic issues
A recent study from the University of Michigan has found that individuals with obesity who engage in long-term exercise have healthier belly fat tissue, allowing for more effective fat storage compared to their non-exercising counterparts.
This finding supports the importance of regular physical activity for metabolic health and offers encouragement for clients who aren’t able to shed fat despite a regular exercise routine.
Study Highlights
The research team wanted to explore the impact of years of exercise on fat tissue. They compared two groups of adults with obesity: 16 participants who reported exercising at least four times a week for an average of 11 years, and 16 individuals who had never exercised regularly but were matched in terms of body fat mass, weight and sex.
Researchers took samples of subcutaneous adipose tissue—fat located just beneath the skin—from both groups. The results showed that the exercisers had distinct structural and biological differences in their fat tissue, including increased blood vessel density, more mitochondria and higher levels of beneficial proteins. They also had lower amounts of collagen that could interfere with metabolism and fewer inflammation-causing cells.
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“Our findings indicate that regular exercise not only helps expend calories but also modifies fat tissue in ways that allow for healthier fat storage during weight gain, which many people experience as they age,” said Jeffrey Horowitz, a professor of movement science at the U-M School of Kinesiology.
The implications of these findings are important. Storing fat in subcutaneous adipose tissue, the type sampled in this study, is considered healthier than fat accumulation around vital organs, which can lead to serious health issues.
Horowitz noted, “Increasing the capacity to store fat here reduces the likelihood of storing fat in unhealthy areas, such as visceral fat around the organs or in the organs themselves.”
This research builds on earlier studies that observed changes in fat tissue after shorter exercise periods. Horowitz emphasized the need for further investigation into how long-term exercise influences fat tissue health and whether specific types or intensities of exercise yield better results.
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This study provides insights for personal trainers, emphasizing the importance of long-term exercise for metabolic health and fat tissue management. Trainers can leverage these findings to educate clients about the broader health impacts of consistent physical activity beyond just weight loss.
Moreover, fitness professionals can design sustainable long-term exercise programs that promote adherence and highlight the health benefits of regular activity, as opposed to pure aesthetics. Understanding that exercise can lead to healthier fat storage may also help address common client concerns about weight gain as they age, fostering a more positive mindset towards fitness.
While the study findings are positive, there are several limitations. The study involved only 32 participants, which may restrict the generalizability of the results. Also, the reliance on self-reported exercise data could introduce bias and inaccuracies in actual activity levels. The research compared current fat tissue characteristics rather than tracking changes over time, limiting insights into how exercise impacts fat tissue development.
The participants were matched based on specific characteristics, which may overlook other influential factors such as genetics and lifestyle. Also of note: the focus on subcutaneous abdominal fat may not capture the full spectrum of fat distribution and health implications, and the controlled setting may not reflect real-world conditions affecting exercise adherence.
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Continued research in this area will further clarify the relationship between exercise, fat storage and overall health, informing best practices in the fitness industry.
At 34, physical therapist Will Harlow works out like someone decades older.
Their goals are very different — his clients are regaining mobility and independence, while Harlow is training to do sports and “look good in a T-shirt.”
But the same basic principles of longevity apply whether you’re 18 or 80.
In his new book, “Independence for Life,” Harlow maps out the four pillars of health that should be baked into anyone’s workout routine: strength, mobility, balance, and healthy bones and joints.
Harlow said one exercise in particular checks all the boxes for longevity and performance, whether you’re a high achiever looking to gain muscle in less time or a fitness newbie trying to build up your health.
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You don’t need a gym or much equipment to get started, so don’t wait, Harlow says — the younger you start training for longevity, the more muscle and fitness you can bank for the years to come.
“There’s no such thing as too early. And the earlier you start, the better of a base you build,” Harlow said.
The best all-in-one exercise for longevity
Harlow’s top exercise for all-around health and fitness is the goblet squat, a movement that trains strength, stability, and mobility at once.
Goblet squats are an accessible exercise — all you need is a dumbbell or other heavy object — and work your whole body at once.
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The exercise involves holding a weight, like a dumbbell or other heavy object, with both hands in front of the chest (as if you’re cupping a giant drinking goblet, as the name suggests).
That’s it — you don’t need a gym or any experience with a barbell, machine, or other equipment, and the risk of injury is low.
“The beautiful thing about the goblet squat is it’s highly safe because if you get into trouble, you can just drop the weight,” Harlow said.
Goblet squats work the entire body at once, engaging the muscles of the back, arms, and legs as you control the weight. As you squat, the joints of your knees, hips, and ankles are working, too. Plus, positioning the weight in front of your body activates your abs and hips.
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Elite athletes and top trainers love goblet squats for building explosive power. For the rest of us, the goblet squat is a simple way to build muscle that’s essential for healthy aging, and mimics real-world activities like sitting down and getting up safely.
“It’s so vital to keep that muscle on our body,” Harlow said. “Strength is just a proxy for independence because if you’re weak, you can’t open heavy doors, you can’t get on and off the toilet unassisted, and you can’t get on and off the floor.”
The longevity ‘sweet spot’
To get the most out of your squat workout, Harlow recommends focusing on a concept called reps in reserve: that’s how many more repetitions you could complete before hitting muscle failure, when you can’t lift anymore.
Research suggests the specific number of reps is less important than challenging your muscles, working until you could barely manage another rep or two if you absolutely had to.
You want a weight you can lift for at least 10 reps, but not more than 20 reps, for the best mix of strength, muscle-building, and health benefits, according to Harlow.
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“That’s a nice sweet spot for building muscle. It’s also heavy enough that you’re going to have an impact on your bone density and you’ll improve your mobility as well, but it’s not so heavy that we are elevating that risk of injury,” he said.
This article is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your qualified physician or healthcare provider.
Twenty minutes, twice a week — that’s the promise behind The Exercise Coach, where artificial intelligence and robotics are helping people rethink what a workout can look like.
“We always start with a leg press, and we get a really good workout on those hamstrings, the quads, the glutes,” said Erica Bennett, trainer at The Exercise Coach.
The workouts are designed for all ages and fitness levels, but many clients are 40 and older. That’s where maintaining strength, balance and muscle mass often becomes a bigger focus.
The proprietary “Exerbotic” machines first measure your strength and range of motion.
“The machine will then use that to create the workout for you, so that you are always spending the most time under tension and the right amount for you,” said Bennett.
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The goal is to keep muscles working continuously while the machine adjusts resistance and movement by staying within the lines of the digital graph above you.
“That’s reducing some of that wear and tear on the joints. That’s creating a little bit of a safer experience, especially for somebody who’s looking at some age-related muscle loss,” said Bennett.
Owner Chris Geiser says the technology is what first caught his attention.
“I love data, I love systems, and this had both of those, but also allowed us to help transform people’s lives, have an impact on their health,” said Geiser.
While the tech drives the workout, every session is still guided by a coach.
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The workout may be short, but it doesn’t feel easy.
The studio also incorporates balance and cognitive training to help clients maintain stability and coordination as they age.
“We don’t need to accept a casual decline of muscle mass. We can keep it up with the right level of intensity and the right frequency,” said Geiser.
For anyone who’s fallen out of an exercise routine, Geiser has a simple invitation.
“You might be surprised what your body can still do. We invite you to give it a shot,” he said.
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The Exercise Coach studio at 8425 Seasons Parkway in Woodbury, Minnesota, opens Friday.
One-on-one coach-led training is $35 to 45 dollars per session.
Scratch the surface, and you might think women have the upper hand when it comes to longevity. According to data from the Office for National Statistics, here in the UK, we live an average of 3.9 years longer than men.
Look a little closer, however, and there’s a catch. Thanks to a longstanding lack of investment in women’s health research, our underrepresentation in clinical trials and fewer treatment options designed for our bodies, we spend 25%more of our lives in ill health than men.
“For decades, hormonal fluctuations were viewed as a ‘complicating factor’ for data,” explains Elliott Roy-Highley, medical director at preventative health studio, Unbound. “As a result, modern medicine suffers from a massive sex-disaggregated data gap.”
That’s why, for women particularly, the question of longevity is not just one of living longer. Instead, our focus has to shift to ways we can stay healthier whilst we’re living: a concept known as healthspan.
The good news is that improving this metric doesn’t require expensive supplements or complicated therapies (just look at Blue Zone populations if you don’t believe me). Research shows quite clearly that a factor like regular exercise is one of the most powerful forms of health insurance we have.
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“A high level of cardiorespiratory fitness reduces the risk of dying from any cause by 53%,” explains Roy-Highley, pointing to a 2024 study in the British Journal of Sports Medicine, “whilst a high level of strength is associated with 31% reduced risk of death from any cause.”
With that in mind, we asked GP and leading longevity doctor, Dr Rhea Kotecha, to share the non-negotiable forms of exercise she believes we should prioritise in order to age well.
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For her thoughts, read on. And whilst you’re here, I recommend checking out our guides to the best longevity workouts, how to hack your longevity from home and the daily longevity habits doctors use themselves. We’ve also got a useful guide to musclespan and the habits we can all borrow from the Blue Zones.
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I’m A Longevity Doctor – These Are The Six Types Of Exercise Every Woman Should Be Doing For Healthy Ageing
How does exercise affect longevity?
When I posed this question to Dr Kotecha, her response was emphatic. “Exercise,” she says, “is the closest thing we have to a longevity drug.”
It’s a glowing endorsement for the role that movement plays in the ageing process, one repeatedly evidenced by research. “The least fit participants had roughly five times the mortality risk of the fittest,” Dr Kotecha says, referencing a 2018 study of over 122,000 adults. “To put that in perspective, being unfit was a bigger risk than being a smoker.”
But what about the risk of too much exercise? Is there a danger that we could go too far? “In theory, yes, but in practice, rarely,” says Dr Kotecha. “The risks live at the extreme end, where years of relentless overtraining can drive up stress hormones, suppress immunity and, in women, switch off the menstrual cycle and erode bone.”
Though this is critical to be aware of, Dr Kotecha says that it’s far more common for women’s health to be compromised by too little exercise. And, she says, in reality “it’s almost never the exercise itself that harms you, but the absence of recovery.”
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Are the longevity benefits of exercise different for men and women?
Due to variations in our biology, muscular and hormonal profiles, it makes sense that exercise would have a different impact on male and female bodies. And in the case of longevity, it turns out things look pretty good for us.
“Essentially, we can do more with less,” says Dr Kotecha, who shares a 2024 study published in the Journal of the American College of Cardiology, which found that women needed to exercise for around 140 minutes a week to reap maximum survival benefits, compared to 300 minutes for men. “What this means is that women get a far better return on investment,” Dr Kotecha explains.
Should your exercise habits change as you age?
It’s not all plain sailing, however. Because as we reach menopause, Dr Kotecha says our biology shifts and this impacts how we need to train. “When oestrogen withdraws, the protection it provides to our bone, muscle and cardiovascular system withdraws with it,” she explains. “This is where training has to step up to fill the gap.”
That doesn’t mean that our exercise routine has to dramatically change in midlife, nor that we have to push our bodies to breaking point. But it does mean that keeping up our fitness in a variety of ways is essential as we age. “What changes across the decades is not which pillars you train, but how you divide the budget between them,” says Dr Kotecha, who says her non-negotiable advice is to remain an all-rounder. “Think of it as a line from performance to preservation. Train now for the answer you want in the future.”
6 types for exercise for staying healthier and living longer, according to top experts:
So, how do we become this exercising all-rounder? According to Dr Kotecha, these six forms of movement are the keys to unlocking healthier ageing.
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1. Strength and resistance training
“Muscle is the organ of longevity,” says Dr Kotecha. “It is your metabolic engine, your glucose sink, your fall insurance and, after menopause, one of your only remaining levers on bone health.”
For that reason, she recommends lifting two to three times a week. “You don’t need to live in the gym,” she reassures, citing research which shows the maximum benefit for longevity lands at roughly 30-60 minutes of resistance training a week. “But you do need to lift things which are genuinely heavy, with the last couple of repetitions feeling hard.”
2. Functional Fitness
Functional fitness, which equates to movement patterns that we use in our day-to-day life, should form a core part of your strength training, says Dr Kotecha. “We want to train the body as one connected system, not as a collection of muscles taking turns on machines. We’re looking for the kind of strength that lets you carry the shopping, a toddler and a suitcase up the stairs. These are the tests of strength that really matter.”
Some of her favourite moves include Turkish get-ups and the farmer’s carry. “These moves build grip, core, coordination and real-world strength all at once,” she explains when asked why she loves them.
The Dumbbell Turkish Get-Up – YouTube
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3. Explosive power
“This is the one almost everyone skips,” says Dr Kotecha, who warns that the impact of neglecting to train for power can be detrimental. “As we lose fast-twitch fibres, we lose stability, increasing our risk of falls and fractures, which in turn increase the risk of mortality and a loss of independence in later life.”
The good news, she says, is that explosive power can be done in small doses and ticked off as part of another session. “You only need about five minutes, but those five minutes might buy you decades of staying on your own two feet,” she explains. “Box jumps, jump squats, hops and a few short sprints are all forms of training explosive power.”
4. Zone two cardio
On the other end of the intensity scale is steady, conversational-pace cardio- think brisk walking, easy cycling or light jogging.
“Nobody posts about this kind of fitness, but everybody needs it,” says Dr Kotecha, who recommends between two and a half and four hours a week of this kind of exercise.
5. HIIT
High intensity interval training has been a contentious topic for women’s training over the years, with debates over whether it has a positive or negative effect on our stress levels and hormonal health.
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The reality, though, is that it’s not an all-or-nothing approach. “The classic mistake is turning everything into a high-intensity session,” says Dr Kotecha. “But short, hard intervals raise your VO2 max efficiently, and VO2 max is one of the strongest survival predictors we have.”
Her recommendation? One to two sessions a week.
6. Stability and balance
It’s far from the most exciting part of an exercise routine, but Dr Kotecha says stability and balance work is highly underrated. “A few minutes of single-leg work, balance drills and mobility most days is possibly the most important thing you will ever do,” she says. “It could be the difference between a stumble and a fracture.”
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Is exercise more important than nutrition for longevity?
It’s tempting to want to rank the things we can do for our health into neatly prioritised boxes. But as Dr Rhea Kotecha, GP and longevity physician, clearly explains, when it comes to nutrition and exercise, one shouldn’t exist without the other.
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“The clinical truth is that you cannot outtrain a poor diet and you cannot out-eat a sedentary body,” she says. “How you train and what you eat are the two strongest, most modifiable levers you have on how long and how well you live, and they only reach their full power together. There is no green powder, no collagen sachet and no supplement that substitutes for being strong and aerobically fit. The basics are boring, and they are also undefeated.”