Sen. Lindsey Graham, the prominent Republican from South Carolina who served in the Senate for more than two decades, died after suffering an aortic dissection, his office said Sunday.

Graham died unexpectedly Saturday night, his office announced, shortly after he had returned to Washington after a trip to Ukraine.

In a statement, his spokesperson said a preliminary report from the medical examiner for the District of Columbia found that the 71-year-old senator died of aortic dissection due to arteriosclerotic cardiovascular disease. With aortic dissection, a tear occurs in the wall of the aorta.

According to the Mayo Clinic, aortic dissection is not very common, and its symptoms may be mistakenly attributed to other health conditions. It usually affects men in their 60s and 70s. If the blood from the dissection travels outside the artery, the condition is often fatal.

A former military lawyer who reached the rank of colonel in the Air Force, Graham ran for the Republican nomination for president in 2016. Initially a cutting, vocal critic of then-candidate Donald Trump during the election, Graham became one of the president’s staunchest allies after Trump’s election.

“Senator Lindsey Graham, one of the greatest people and Senators I have ever known, is dead!” Trump posted on his social media platform, Truth, on Sunday. “He was always working, and was a true American Patriot.”

Graham was known as a C student in high school, and was the first member of his family to attend college. His mother died while he attended the University of South Carolina, and his father died of a heart attack during Graham’s first semester of law school.

He served as a judge advocate in the Air Force, eventually becoming the chief prosecutor for the Air Force in Europe.

He was first elected to serve as senator for South Carolina in November 2002.

In a social media post on X, Vice President JD Vance described Graham as one of the most powerful lawmakers, and recalled an incident where he and Graham got into a shouting match over a funding bill for the war in Ukraine.

Later the same day, he wrote in the post, Graham was advocating for rail legislation that Vance supported.

“That was Lindsey Graham,” he wrote. “He fought like hell for the things he believed in, and he was just as willing to go to bat for you when it counted.”

Graham had been scheduled to appear on NBC’s “Meet the Press” on Sunday to discuss his trip to Ukraine. Instead, President Trump appeared in his stead, where he said the senator had been “like a member of the family.”

Trump called into several Sunday news programs to discuss Graham’s death, and said he had spoken to Graham on Saturday evening.

Trump told CNN’s Jake Tapper that the South Carolina senator had said he was “tired.”

President Donald Trump is pushing for an unexpected replacement to fill the vacancy left by the late Sen. Lindsey Graham, R-S.C., in the Senate.

Trump wants South Carolina Gov. Henry McMaster to tap Graham’s sister, Darline Graham Nordone, to be appointed to the lawmaker’s suddenly open seat for the remainder of his term.

“I recommended, to Governor Henry McMaster, Lindsey Graham’s wonderful sister, Darline, to serve as interim Senator from the Great State of South Carolina,” Trump said on Truth Social on Monday. “This would be a fabulous tribute to Lindsey, who loved her dearly!”

Graham and his younger sister, Darline, had a unique bond, given that, after their parents died, the lawmaker legally adopted and raised her.

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Trump’s announcement comes as a scramble behind the scenes is taking place to fill Graham’s spot, and further, find a new GOP nominee to run in November to keep his seat in the hands of Republicans.

McMaster is expected to announce his pick for the seat at 4 p.m. on Monday. He has so far kept quiet about who he would prefer. Fox News Digital did not immediately hear back from McMaster’s office on who he is eyeing in the interim.

Meanwhile, a key Republican, Sen. Tim Scott, R-S.C., also wants to see Graham’s sister get the nod for his seat.

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“Lindsey Graham’s sister, Darline Graham Nordone, would be a fantastic pick to serve out the remainder of the Senate term,” Scott said on X. “After speaking with Darline, there is no one better who understands Lindsey’s love for family, our state, and our country.”

Scott, earlier in the day, floated both former Rep. Trey Gowdy and former Sen. Jim DeMint as possible replacements in the interim. He hoped that McMaster would “put a placeholder and let the voters decide” later during a forthcoming special election.

“I think in the next several hours or next day or so we’ll figure out who that person is,” Scott said. “I love Trey Gowdy and Jim DeMint has been in the conversation.”

“[Graham’s] sister would be a wonderful placeholder as well,” he continued. “So we’ve got lots of candidates who could hold the place so that the voters decide. And remember the election starts August the 11th in South Carolina, three weeks from now, we’ll have a primary process.”

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Both Gowdy and DeMint have served in Congress — Gowdy in the House and DeMint in the Senate, preceding Scott. Graham Nordone, however, has never held public office.

Multiple sources close to Scott, who chairs the National Republican Senatorial Committee (NRSC) told Fox News Digital that he is pushing McMaster to choose one of the three to effectively be a placeholder and not seek a six-year term in the Senate.

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While the appointment race nears its conclusion, the race for the GOP nomination to run in South Carolina is still wide open.

Reps. Nancy Mace, R-S.C., and Ralph Norman, R-S.C., are already hinting at leaping into the special election, which is set for Aug. 11. Rep. Joe Wilson, R-S.C., said that he would stay in the House, but the rest of the Palmetto State’s GOP congressional delegation have not said what their plans are.

California Atty. Gen. Rob Bonta and 11 other Democratic state attorneys general filed a lawsuit Monday to block Paramount Skydance’s proposed $111-billion takeover of Warner Bros. Discovery — a last-ditch effort to derail a deal that would transform Hollywood.

Tech scion David Ellison’s proposed merger has been hurtling toward the finish line after securing approvals from the U.S. Justice Department and numerous foreign governments. President Trump, an ally of Ellison’s billionaire father Larry Ellison, favors the deal. He is eager for a big shakeup at CNN, which is currently controlled by Warner Bros.

David Ellison now faces his biggest challenge yet as he attempts to build a new entertainment behemoth.

A Paramount representative did not immediately comment.

The suit, filed in federal court in San Francisco, alleges that the proposed merger would violate the U.S. Clayton Act, a century-old antitrust law to prevent mergers that weaken competition and increase costs for consumers.

“Consolidation here not only leads to higher prices — it also leads to fewer opportunities for important stories to come to life, and fewer ways for audiences to encounter stories, ideas, and perspectives beyond their own experiences,” Bonta said in a statement.

“California and our sister states are fighting for free and fair markets, not rigged markets,” he said.

California and the 11 other states, including New York, New Jersey, Washington and Colorado, allege the merger would devastate the theatrical film business by combining two historic film studio rivals. The Ellison family would control such storied franchises as Harry Potter, Bugs Bunny, Batman, “Top Gun” and “Game of Thrones.”

The proposed purchase also would unite two prominent news organizations — CNN and CBS News.

The states have asked Paramount to delay the closing of its Warner Bros. takeover until the litigation can be resolved.

If Paramount refuses, Bonta said the coalition would seek a temporary restraining order asking a judge to hold up the merger, a move that would cause costly delays and escalate legal expenses for Paramount in their quest to finalize the deal.

Larry Ellison, co-founder of software giant Oracle, is bankrolling his son’s ambitions to acquire a second major entertainment company in less than a year. The Ellison family acquired control of CBS-owner Paramount in August and, at the time, David Ellison touted the move of Paramount’s headquarters from New York’s Times Square to Hollywood.

Now, Paramount is reportedly threatening to leave California in the face of Bonta’s legal action.

If the merger goes through, Paramount would own four streaming services, including Warner’s HBO Max and the dominant U.S. cable TV channel owner with HBO, TBS, HGTV, Animal Planet, Food Network, Comedy Central and Nickelodeon.

The U.S. Justice Department last month approved the merger, saying the combination would likely bolster competition — not harm it. The agency’s decision had been expected because of Larry Ellison’s strong support of Trump.

In a show of confidence earlier this year, the Ellisons agreed to increase the payout to Warner investors should the regulatory approval process drag on. Those extra 25-cent-per-share payments begin with the October-December quarter, and would add more than $650 million in deal costs each quarter — giving David Ellison an increased incentive to quickly close the deal.

The proposed merger has sparked fears in Hollywood that it will bring thousands of job losses — similar to past consolidations, including Walt Disney Co.’s 2019 takeover of Fox entertainment properties.

Some theater owners, hard hit by the pandemic and production slowdowns, have expressed concerns the merger would lead to fewer films being made.

The new colossus would significantly dampen competition, Bonta and the other Democrat prosecutors argue. They pointed to the wide-release movie film distribution business, where Warner Bros. and Paramount control about 27% of the market.

After the merger just four companies — Paramount-Warner, Disney, NBCUniversal and Sony Pictures — would control 86% of the films that were widely released, Bonta said.

Paramount has said the deal will boost competition — not hamper it. Ellison has promised to continue releasing 30 films a year with a combined Warner Bros.-Paramount studio, roughly the current output of the two studios.

Ellison also vowed to protect the HBO brand.

Another concern is the licensing of basic cable TV channels, including CNN and HGTV, to pay-TV providers such as Charter’s Spectrum, DirecTV and Google’s YouTube TV. Warner Bros. is the second largest cable channel owner and Paramount is the third largest. Together their channels would represent about 27% of the market.

The typical threshold for antitrust concerns is at least 30% marketshare.

More than 5,000 entertainment industry workers, including Jane Fonda, Ben Stiller, Bryan Cranston, Javier Bardem, Lin-Manuel Miranda and Mark Ruffalo, signed an open letter calling on Bonta to block the merger.

Some have expressed concerns about marrying CNN and CBS News following months of turmoil at CBS News since David Ellison hired journalist Bari Weiss as CBS News editor in chief. Last month, Weiss orchestrated a dramatic shakeup at the iconic “60 Minutes” news program, with top executives and three well-known correspondents tossed out.

The Ellison family recently shed its movie theater chain, which it picked up as part of the Paramount acquisition, to clear the way for the Warner deal.

The deal also faces opposition outside the U.S.
. The British culture minister in late June said she was weighing whether to intervene in the deal due to concerns about maintaining a competitive media market. Britain’s Competition and Markets Authority also has opened an investigation into Paramount’s proposed merger.

In April, a federal judge in Sacramento granted a request from Bonta and seven other attorneys general for a preliminary injunction, which freezes the merger of Nexstar Media Group, which owns KTLA-TV Channel 5, and Tegna. The deal was designed to create the nation’s largest TV outlet group .

A larger group of state attorneys general also won a New York jury verdict against Live Nation Entertainment and its subsidiary Ticketmaster. Jurors found that Live Nation had illegally monopolized the live concert industry.

Bonta also has an ongoing case against Amazon for price fixing, which the company denies.

Still, legal experts say the states may face an uphill climb to detrail the Paramount-Warner Bros. merger because the arrival of Netflix, Amazon and Apple dramatically shifted the landscape.

The tech giants, which introduced consumer-friendly streaming options, have lessened the influence of traditional companies like Paramount and Warner Bros.

Paramount’s deal would mark the third time Warner has changed hands in the last decade.

AT&T bought the company in 2018 and then sold it to the smaller Discovery four years later. That deal left Warner Bros. burdened by debt, leading to deep cost cuts and setting the stage for the Ellison takeover.