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Stomach issues might have nothing to do with eating habits, scientists reveal why

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Stomach issues might have nothing to do with eating habits, scientists reveal why

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In addition to taking an emotional toll, childhood stress and hardships can also wreak havoc on the digestive system.

New research published in the journal Gastroenterology revealed that early experiences can rewire the body, leading to lifelong stomach issues.

Scientists at New York University focused on communication between the brain and the gut, finding that when a child experiences significant stress, this connection is disrupted.

TOXIC PEOPLE IN YOUR LIFE MAY HAVE A HIDDEN HEALTH IMPACT, STUDY SUGGESTS

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That disruption can manifest years later as irritable bowel syndrome, chronic stomach pain or motility issues like constipation and diarrhea.

“Our research shows that these stressors can have a real impact on a child’s development and may influence gut issues long-term,” study author Kara Margolis, a professor at NYU, said in a press release.

The presence of flagellin antibodies long before symptoms appear suggests the immune reaction may help trigger the disease rather than result from it. (iStock)

“When the brain is impacted, the gut is likely also impacted — the two systems communicate 24 hours a day, seven days a week,” she added.

The study looked at both animal models and long-term data from over 40,000 children in Denmark and 12,000 in the U.S. 

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Researchers found that mice subjected to early-life stress showed higher levels of anxiety and gut pain. Mice symptoms varied by gender, as females were more prone to diarrhea and males were more prone to constipation.

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Children whose mothers had depression during or after pregnancy, or those who had more emotionally difficult childhoods, were more likely to develop digestive disorders as early as age 10, the researchers noted.

Children who had harder childhoods were more likely to develop digestive orders as early as age 10. (iStock)

Unlike the mouse studies, the human data showed no differences between males and females in digestive outcomes, which suggests that early stress may affect gut-brain health for both genders during key stages of development.

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The results show how symptoms are controlled by different “pathways” in the body, doctors said. For example, the nerves responsible for gut movement are separate from the pathways that control gut pain.

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This means there is no single cure for gut issues, the team stated. If a patient has pain but no motility issues, they would need a different treatment than someone who has constipation but no pain.

By identifying these specific biological triggers, scientists say they are moving toward more personalized treatments that target the root cause of a patient’s symptoms.

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The team says these results are evidence that there is no one-size-fits-all approach to gut issues. (iStock)

“When patients come in with gut problems, we shouldn’t just be asking them if they are stressed right now; what happened in your childhood is also a really important question and something we need to consider,” said Margolis.

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“This developmental history could ultimately inform how we understand how some disorders of gut-brain interaction develop and treat them based on specific mechanisms.”

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs


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What Is Zepbound? Weight-Loss Benefits, Costs and Dosage




















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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

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Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

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The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

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New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities. 

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment. 

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

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Tai Chi Walking Boosts Weight Loss After 50—With Less Joint Pain and Stress

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Tai Chi Walking Boosts Weight Loss After 50—With Less Joint Pain and Stress


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Tai Chi Walking Boosts Weight Loss and Eases Joint Pain




















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