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Behind his smile, a silent crisis: Parents seek answers after autistic son’s suicide

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Behind his smile, a silent crisis: Parents seek answers after autistic son’s suicide

When Anthony Tricarico was diagnosed at 7 with autism spectrum disorder, his parents, Neal and Samara, were told that he might need extra support at school, so they made sure he got it. When doctors suggested therapies for his speech and motor skills, they sought those out too.

But when their kind, popular, accomplished boy began to experience depression and suicidal ideation as a teenager, no one told them that the same thinking patterns that powered many of Anthony’s achievements might also be amplifying his most harmful thoughts, or that the effort of masking his autism could be hurting his mental health.

None of the people or organizations they contacted for help said Anthony might benefit from therapies or safety plans adapted for autistic people, or even that such things existed. They did not say that he might not show the same warning signs as a non-autistic teenager.

Neal Tricarico holds one of many rocks in honor of his son Anthony that friends and relatives have left in a memorial garden.

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And only after he died from suicide in May 2024 did the San Diego County couple discover that autistic kids — particularly those like Anthony, whose disability is not immediately apparent from the outside — are more likely to think about and die from suicide, and at earlier ages, than their neurotypical peers.

“Our son has always been different. So why wouldn’t how we approach suicide be different?” Neal said.

Suicide is a leading cause of death in the U.S. for kids aged 10 to 18. Prevention strategies that take neurodiversity into account could go a long way toward reducing the number of young lives lost too soon.

Autism researchers and advocates are working to develop better screening tools and interventions based on the unique strengths and differences of an autistic brain. A crucial first step is educating the people best positioned to help kids when they’re in crisis, like parents, counselors, pediatricians and social workers.

“We’re aware of the need for tailored approaches. We’re doing this research. We’re trying to get the word out.”

— Danielle Roubinov, University of North Carolina at Chapel Hill

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“These are kids that are experiencing all sorts of heightened risk,” said Danielle Roubinov, an associate professor and director of the Child and Adolescent Anxiety and Mood Disorders Program at University of North Carolina at Chapel Hill. “We’re aware of the need for tailored approaches. We’re doing this research. We’re trying to get the word out. And [suicidality] is something that is treatable. This is something that responds to intervention.”

The percentage of U.S. children with an autism diagnosis has risen steadily in recent decades, from 1 in 150 8-year-olds in 2000 to 1 in 31 in 2022.

The diagnostic definition has changed dramatically in that time, inscribing children with a broad range of abilities, needs and behaviors within a single term: autism spectrum disorder.

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Today, the diagnosis includes children whose autism was previously overlooked because of their propensity for “masking,” the act of consciously or unconsciously suppressing autistic traits in order to blend in.

Samara and Neal Tricarico with a large photograph of their son,  Anthony, in their home

Samara and Neal Tricarico with a portrait of Anthony at their home.

For autistic children without intellectual disabilities, like Anthony Tricarico, masking often enables them to participate in mainstream classes or activities. It’s also why many children, especially girls, aren’t diagnosed with autism until later in childhood.

Masking can exact a powerful psychological toll on autistic kids, and is strongly correlated with depression, anxiety and suicide.

Anthony Tricarico was bright, athletic and autistic. His parents, Neal and Samara Tricarico, share what they wish they’d known when their son first started to struggle with his mental health.

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Children across the autism spectrum are far more likely to struggle with mental health conditions than their allistic, or non-autistic, peers. A 2021 study of more than 42,000 caregivers of children ages 3 to 17 found that 78% of autistic children had at least one co-occurring psychiatric condition, compared with 14% of non-autistic kids. Contributing factors include the stress of living in a world that’s sensorially overwhelming or socially impenetrable. Lights, noises, smells and crowds that others barely notice may cause incapacitating anxiety.

For kids who cope by masking, constantly deciphering and mimicking social responses is often cognitively and emotionally exhausting. “Masking is actually a risk factor of suicide for autistic people,” said Lisa Morgan, founder of the Autism and Suicide Prevention Workgroup, who is autistic herself.

A rock displaying the message, "Sometimes I look up, know that you and I smile"

One of many rocks in honor of Anthony that have been left in the family’s memorial garden.

Autistic people at all ages are more likely to die by suicide than those who aren’t autistic. That disparity begins early. One 2024 meta-analysis found that some 10% of autistic children and teens had attempted suicide, a rate more than twice that of non-autistic peers.

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Their struggles are often invisible.

Neal and Samara had never heard of masking.

They saw how Anthony thrived on schedules and sameness. He rose precisely at 5 a.m. for a long workout, chugged the same protein shake afterward, took a shower at 7 a.m. on the dot. At the time they thought he was extremely disciplined; they believe now it was also Anthony’s way of fulfilling his need for routine and predictability, a common autistic trait.

They also saw that he preferred to keep his diagnosis a secret.

Anthony's black belt in karate rests on a table in the family home.

Anthony’s black belt in karate rests on a table in the family home.

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In middle school, Anthony announced that he no longer wanted any accommodations for his autism: no more individualized education program, no more behavioral therapy, no more telling new friends or teachers about his diagnosis.

“It’s my belief he just wanted all that to go away, and to just be like everyone else,” Neal said.

The pandemic hit Anthony hard. He couldn’t work out at his favorite spots or fish, a beloved pastime. Other kids might have defied the closures and gone anyway, but Anthony followed rules with inflexible intensity, Neal said, especially the ones he set for himself.

His mental health started to decline. In 2022, during his freshman year, Neal and Samara learned that Anthony told a friend he was having thoughts of suicide.

They called the California suicide hotline, where a volunteer told them to contact his school. A counselor determined that since Anthony didn’t have a plan, he wasn’t at immediate risk.

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When Neal and Samara asked him about it, he sounded almost dismissive. It was fleeting, he said. It wasn’t real.

Neal Tricarico looks over a living room table covered in photographs and medals.

Neal looks over a living room table covered in photographs and medals Anthony won in 5Ks, half marathons and other athletic competitions.

It’s impossible to know Anthony’s true thoughts. What is known is that suicidal ideation can look very different in autistic kids.

About a decade ago, psychiatrist Dr. Mayank Gupta started noticing an uptick in a particular type of patient at the western Pennsylvania inpatient facilities in which he worked: bright children from stable home environments who began having serious suicidal thoughts in early adolescence.

They showed few of the typical youth-suicide risk factors, like substance use or histories of neglect. A surprising number had autism diagnoses.

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At the time, Gupta associated autism with behaviors like minimal verbal communication and noticeable differences in body language or eye contact. Nothing in his training or continuing education discussed the breadth of the autism spectrum, or how it might relate to children’s mental health.

He searched the literature, and was stunned to find how much published work there was on autism and suicide.

“In the last seven to eight years, there’s been more and more evidence, and more and more research,” he said. But not enough of it has made its way to the local psychologists, psychiatrists and pediatricians that parents are most likely to turn to for help with a struggling child.

Adults often assume that a child who can speak fluently on a variety of subjects can explain their thoughts and feelings with a similar level of insight. But up to 80% of autistic kids have alexithymia, or difficulty identifying and describing one’s own internal emotional state. For this reason, “it makes sense that all of the interventions that have been designed for a neurotypical youth probably aren’t going to translate in the same way to autistic youth,” said Jessica Schwartzman, director of the Training and Research to Empower NeuroDiversity Lab at Children’s Hospital Los Angeles and assistant professor of pediatrics at USC’s Keck School of Medicine.

Autistic people are often stereotyped as unable to read other people, Morgan said, but neurotypical people often have just as hard a time accurately interpreting an autistic person’s emotional state.

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“What people are looking for is that really outward display of emotions and tears and angst,” said Morgan, of the Autism and Suicide Prevention Workgroup. “But for autistic people, that all can be happening on the inside without the autistic person being able to communicate that. And in fact, the further in crisis they go, the less they’re able to verbally communicate.”

As high school progressed, Anthony gave “the appearance of thriving,” Neal said: a 4.6 grade-point average, two part-time jobs, a busy social life. He ran marathons and finished grueling Spartan Races.

“But for us, living with him every day, we saw the black-and-white thinking really, really intensify,” Neal said. “The intensity and speed with which he was coming up with new things to achieve became more and more, and the feeling of lack of fulfillment became even greater.”

“Living with him every day, we saw the black-and-white thinking really, really intensify.”

— Neal Tricarico, Anthony’s father

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In 2023, Anthony told his mother that the suicidal thoughts were back. He wanted to go to an inpatient facility that could keep him safe.

They dialed every number they could find. They called a county mobile crisis response team, which determined that since Anthony had no clear plan, he likely wasn’t at risk. They called a therapist he’d seen when he was younger. But Anthony was clear: He wasn’t OK and needed to be somewhere that could help.

When they finally found a facility able to admit him, they checked him in with a sense of relief. Immediately, they all felt they’d made a mistake.

Some of the medals Anthony won in marathons, Spartan Races and other competitions.

Some of the medals Anthony won in marathons, Spartan Races and other competitions.

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The only available bed was in solitary confinement. He couldn’t exercise, go outside or follow his routines.

Emergency rooms or inpatient facilities are sometimes the only option to keep someone safe during a suicidal crisis. But separated from familiar settings, objects and routines, and inundated with stimuli like bright lights, many autistic kids find them more disturbing than therapeutic, researchers said.

“The people that work in those facilities are obviously incredible, but they may or may not have special training in strategies and communication practices and approaches that are tailored to meet the needs of autistic individuals,” Roubinov said.

Anthony called his parents begging to come home. After two nights, the Tricaricos signed him out. On the way home Samara asked him to promise he’d tell them if he ever had suicidal thoughts again.

“He said, ‘No. I will never,’” she recalled.

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His parents interpreted his words to mean he’d never think that way again, and that the worst was over. They now believe he was really saying that he had lost hope.

Another year passed. In March 2024, Anthony and his sister met up with friends who later said he seemed happier than he’d been in a while. He gave one an envelope of cash he’d saved and told her to take herself to Disneyland.

He was surrounded by people who cared about him, all unaware that he was displaying classic warning signs of an imminent crisis: giving away valuables, a sudden lift in spirits, indirectly saying goodbye.

The next day he was quiet and downcast.

“I could tell he had been crying, and I said, ’What’s going on? Is it friends? Is it work? Is it school work?’” Samara recalled. “And he said, ‘It’s all of it.’”

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That afternoon, after finishing his chores, Anthony told his parents he was going for some fresh air, which he often did to clear his head. They could see on their phones that he was taking a familiar route through their Cardiff-by-the-Sea neighborhood.

His icon paused. Maybe he got a phone call, his parents thought, or bumped into friends.

Dusk fell. Samara’s phone rang with a call from Anthony’s number. It was a sheriff’s deputy. They’d found him.

Anthony spent nine weeks in the hospital. He died on May 25, 2024. He was 16 years old.

Colorful, painted rocks in honor of Anthony decorate a memorial garden.

Colorful, painted rocks in honor of Anthony decorate a memorial garden.

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Months later, Neal got a message from a Facebook friend who worked at a suicide-prevention foundation, asking if he knew about the particular risks facing autistic kids.

It was the first time he’d heard of anything of the sort.

They scheduled a Zoom call and she walked him through all of it: The stats, the research, the reasons that warning signs for kids like Anthony can look so different that the most attentive parents can miss them.

There is no simple explanation for why any one individual dies by suicide. As seriously as Neal and Samara took their son’s mental health struggles, it was impossible to imagine him ending his life. It didn’t fit with his zeal for living or his disdain for shortcuts. In retrospect, they say, it was also too frightening to contemplate.

“You drive yourself crazy saying, ‘what if.’”

— Samara Tricarico, Anthony’s mother

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But had they known how common such thoughts and actions are for young people in Anthony’s sector of the autism spectrum, they said, they would have approached it differently.

“You drive yourself crazy saying, ‘what if,’ Samara said. “But I would have liked to have known that, because it potentially could have saved his life.”

About 20% of U.S. high schoolers disclosed suicidal thoughts in 2023, according to the Centers for Disease Control and Prevention. When the Kennedy Krieger Institute in Baltimore asked caregivers of 900 autistic children if the children had thought about ending their lives, 35% said yes. Nearly 1 in 5 had made a plan. The youngest respondent was 8 years old.

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The risk may be particularly high for gifted kids trying to function in a world designed for a different way of thinking. In one 2023 study from the University of Iowa, autistic kids with an IQ of 120 or higher were nearly six times more likely to have suicidal thoughts than autistic children with average IQ. For non-autistic children, the opposite was true: Higher cognitive ability was associated with a decreased risk of suicide.

There’s no clear protocol for families like the Tricaricos. There are therapists and psychiatrists specially trained in autism, but not enough to meet demand.

Researchers are, however, looking for ways to tailor existing therapies to better serve autistic kids, and to educate healthcare providers on the need to use them.

One starting point is the Columbia-Suicide Severity Rating Scale, the standard that healthcare professionals currently use to identify at-risk children in the general population. Schwartzman’s lab found that when the questionnaire was administered verbally to autistic kids, it flagged only 80% of those in the study group who were having suicidal thoughts. A second, written questionnaire identified the other 20%. Schwartzman recommends that providers use a combined spoken and written screening approach at intake, since some autistic people find text questions easier to process than verbal ones.

Another candidate for adaptation is the Stanley-Brown safety plan, a reference document where patients list coping strategies, helpful distractions and trusted contacts on a one-page sheet that can be easily accessed in a crisis. Research has found that people with a completed plan are less likely to act on suicidal thoughts and more likely to stick with follow-up care. It’s cheap and accessible — free templates in multiple languages can be easily found online.

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But like most mental health treatments, it was developed with the assumption that the person using it is neurotypical. There isn’t much research on whether the Stanley-Brown is less effective for autistic people, but researchers and advocates say it stands to reason that some tailored adjustments to the standard template could be helpful.

Shari Jager-Hyman, a clinical psychologist and assistant professor at the University of Pennsylvania’s Perelman School of Medicine, and Lisa Morgan of the Autism and Suicide Prevention Workgroup are creating an autism-friendly version.

Some changes are as simple as removing numbered lines and leaving blank space under headings like “Sources of support.” Many autistic people think literally and may perceive three numbered lines as an order to provide exactly three items, Morgan said, which can be especially disheartening if there aren’t three people in their circle of trust.

Jager-Hyman and Roubinov, of UNC, are currently leading a study looking at outcomes for suicidal autistic children who use the modified Stanley-Brown plan.

The way adults interact with autistic children in crisis may also make a difference. Sensory overload can be extremely destabilizing, so an autistic child may first need a quiet place with dim lighting to calm themselves, and extra time to process and form answers to providers’ questions.

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For parents and other caregivers, the best thing they can offer might be a quiet, supportive presence, Morgan said: “For an autistic person, it could be they want somebody there with them, but they just want to sit in silence.”

The knowledge Neal and Samara have acquired since losing Anthony has felt to them like a missing piece that makes sense of his story, and a light illuminating their path ahead.

Earlier this year, they founded the Endurant Movement, a nonprofit dedicated to autism, youth suicide and mental health. They have joined advocates who say the most effective way to reduce rates of depression, anxiety and the burden of masking is to ensure that autistic kids have the support they need, and don’t feel like they have to change everything about themselves in order to fit in.

“Suicide prevention for autistic people is being accepted for who they are, being able to be who they are without masking,” Morgan said.

The Tricaricos imagine interventions that could make a difference: practical, evidence-based guidelines that families and clinicians can follow when an autistic child is in crisis; information shared at the time of diagnosis about the possibility of co-occurring mental health conditions; support for autistic kids that frames their differences as unique features, not deficits to be overcome.

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And above all, a willingness to have the hardest conversations before it is too late.

“Suicide prevention for autistic people is being accepted for who they are, being able to be who they are without masking.”

— Lisa Morgan, Autism and Suicide Prevention Workgroup

There is a common misconception that asking about suicide could plant the idea in a child’s head and lead to further harm. If anything, researchers said, it’s protective. Ask in whatever way a child is comfortable with: a text, a written letter, in conversation with a trusted therapist.

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“Suicide is so stigmatized and people are so afraid to talk about it,” Samara said. “If we can talk about it, invite the conversation, we can normalize it so they can feel less alone.”

She and Neal were seated next to each other on a bench in their front garden, surrounded by rocks friends and family had painted with tributes to Anthony.

“We didn’t know that our son was going to take his life this way. If we knew that having the conversation could help, we would have,” she said, as Neal nodded.

“And so that’s the message. Have the conversation, as difficult as it feels, as scary as it is … . Have the courage to step into that, knowing that that could possibly save someone’s life. Your child’s life.”

If you or someone you know is struggling with suicidal thoughts, seek help from a professional or call 988. The nationwide three-digit mental health crisis hotline will connect callers with trained mental health counselors. Or text “HOME” to 741741 in the U.S. and Canada to reach the Crisis Text Line.

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This article was reported with the support of the USC Annenberg Center for Health Journalism’s National Fellowship’s Kristy Hammam Fund for Health Journalism.

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L.A. region begins the year with the smoggiest first 5 months in a decade

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L.A. region begins the year with the smoggiest first 5 months in a decade

The first five months of 2026 in Southern California have been the smoggiest — with the highest number of unhealtful air days — in more than a decade, according to statewide air monitoring.

So far this year, the South Coast air basin, which includes Los Angeles, Orange, Riverside and San Bernardino counties, has seen 39 days when the concentration of lung-irritating ozone (commonly known as smog) exceeded the federal standard, according to preliminary state air quality data.

That’s even worse than the infamously hot and hazy 2017, when Greater Los Angeles had 36 unhealthful air days by June 4 and ultimately saw 145.

Many of the roughly 18 million people who live in the air basin have been subjected to unhealthful levels of ozone, a highly corrosive gas that triggers asthma attacks and a wide range of respiratory illnesses. This has taken many by surprise since successive days of smog more commonly happen in summer, when heat waves and intense sunlight convert man-made pollution into ozone.

“If we have this many violations by this time, this could be a really awful year for air quality,” said Adrian Martinez, director of Earthjustice’s Right to Zero campaign, an initiative calling for the transition away from fossil fuels. “We’re already the worst place in the country for summertime smog pollution. So it could be one of the worst years in one of the worst places in the country.”

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The pollution has been especially severe in valleys. On April 18, an air monitor in Reseda in the San Fernando Valley measured the second highest spike in hourly ozone levels in the last decade.

Greater Los Angeles has seen more high-smog days so far in 2026 than any other year in the past decade.

(Courtesy of South Coast Air Quality Management District)

The South Coast Air Quality Management District says the high ozone levels are due to early heat waves. Officials said they were not aware of any increase in the pollutants — most of them from different kinds of exhaust — that lead to ozone formation.

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Local temperatures have been well above normal, climbing into the mid-80s and high 90s between January and April, breaking several daily high temperature records, according to the National Weather Service.

March in particular was the warmest on record in California. Riverside had an unprecedented 13 days of temperatures above 90 degrees, the weather service said.

“It was really that heat wave — conditions we typically see in July or August, we saw them in March,” said Sarah Rees, deputy executive officer of the air district. “That put us ahead of the curve in terms of how much ozone we got.”

Air district officials urged residents to monitor pollution levels on the agency’s website and mobile app, and spend only limited time outdoors when smog levels are high.

“People generally know when there’s a wildfire, because you see the smoke and smell it,” said Scott Epstein, the air district’s manager of planning and rules. “Then, it’s like, I’ve got to take precautions. Ozone, you can’t really tell.”

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Southern California has been particularly susceptible to smog formation because of its millions of gas-powered cars releasing tons of tailpipe emissions each day. The region’s sunshine acts as a catalyst for smog formation. Then the mountains trap this pollution over densely populated communities.

For nearly half a century, state and local air regulators have made rules designed to alleviate this pollution, enacting the nation’s first tailpipe emission standards in 1966 and requiring catalytic converters in 1975.

Smog-forming pollution has been dramatically reduced over the last two decades, but the region still does not meet federal air quality standards for ozone.

At an air district meeting Friday in Diamond Bar, the governing board held a moment of silence for William Burke, a former longtime chair. During his tenure, the agency enacted nearly 270 rules that are credited with reducing smog-forming pollution by hundreds of tons per day. Burke, who also founded the Los Angeles Marathon, died in May at 87.

“Those are just emission reductions,” air district Chair Michael Cacciotti said at the Friday meeting. “But what it doesn’t tell you is how many kids, families, seniors were prevented from going to the hospital from an asthma attack, didn’t get cancer or other respiratory problems.”

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Several residents from the Inland Empire, which suffers some of the worst smog pollution, expressed their appreciation for the air district’s efforts. But they also stressed the need for more progress.

“I’m old enough to remember growing up in the ‘70s and ‘80s … and not being able to see the mountains for weeks and months at a time,” said Erik Morden, one of several residents who spoke at the meeting.” I know things have improved, and I want to thank all of you for all the hard work that you’re doing. But there’s a lot of invisible stuff that you don’t see, that’s still out there — a lot of particulates in the ozone and chemicals that are causing a lot of problems.”

Martinez, the Earthjustice attorney, said the abnormally early outbreak of smog should be a wake-up call to government regulators that there’s work to be done, including offering more incentives to help residents and businesses transition to zero-emission appliances.

“We shouldn’t over-complicate it. We’ve got a lot of heat, we’ve got a lot of pollution,” Martinez said. “Our contention is, this agency can’t control the weather. But the one thing it can control is the pollution.”

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A flesh-eating worm from the 1960s is re-invading the U.S. Are CA cattle at risk?

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A flesh-eating worm from the 1960s is re-invading the U.S. Are CA cattle at risk?

Federal agricultural inspectors detected a case of New World screwworm larvae — maggots that burrow into the flesh of living animals and sometimes humans — on a 3-week-old calf in south Texas, near the U.S.-Mexico border. Officials anticipated the arrival of screwworm in the United States and say they’re prepared to contain it.

New World screwworm, also known as Cochliomyia hominivorax, is starkly different from the average maggot that feeds on decaying organic matter such as garbage, rotting food or dead animals, said Tom Talbot, veterinarian and member of the California Cattlemen’s Assn.

That’s because a screwworm larva “attacks living flesh,” Talbot said.

On Thursday, the U.S. Department of Agriculture confirmed the detection of New World screwworm in the umbilical area of a bovine in Zavala County, Texas, more than 60 miles from the northern Mexico border.

As of Friday morning, there have been no additional cases of infected animals reported.

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Screwworm is endemic in South America and parts of the Caribbean, according to the Centers for Disease Control and Prevention. However, the parasitic fly has been steadily moving north from Central America to Mexico since 2023.

The USDA says it has actively monitored the fly’s movement. Last month, the USDA was aware of more than 200 active screwworm infestation cases in the border states of Nuevo León and Tamaulipas, according to Mexico’s Secretary of Agriculture and Rural Development dashboard. There are currently more than 2,000 active cases throughout Mexico.

It was believed that the New World screwworm would enter the U.S. in 2025, “however, thanks to the hard work across the entire Trump administration and our industry, state, and local partners, we were able to buy time for this moment,” said Dudley Hoskins, undersecretary for Marketing and Regulatory Programs for the USDA, in a statement.

The potential economic impact of New World screwworm on the cattle industry due to import restrictions, reduced productivity and animal loss is substantial, said Sally DeNotta, director of the University of Florida’s Equine Performance Laboratory.

Last year, 175 key agricultural organizations signed a letter urging additional federal funding for screwworm-control measures, emphasizing USDA estimates that a New World screwworm outbreak in the U.S. could cost producers $4.3 billion annually and cause economic losses of more than $10.6 billion across the southern United States.

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“While the fly does not survive at temperatures at or below freezing, infected animals could carry the parasite northward and spread infection during the summer months, and the temperate climate of Southern California could certainly support year-round New World screwworm populations,” DeNotta said.

Talbot said from the federal to the local level, everyone in the ranching community has been talking about the arrival of screwworm and how to combat it.

“My expectation is that there will be a minimal number of cases of [New World screwworm] in California,” he said.

That’s because there are several stations on the border in Southern California, he said, that are collecting data, monitoring for any incidents of the parasitic fly and trapping them.

Talbot says he’s confident that the proactive measures on behalf of the federal government will mitigate the screwworm’s reach and therefore not impact the beef supply locally or nationally.

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How screwworm infection spreads

Female screwworm flies are attracted to the smell of wounds — that can be as small as a tick bite — and body openings such as the nose, eyes, ears and mouth where they can lay eggs, according to the CDC.

A female screwworm fly can lay 200 to 300 eggs at a time and may lay up to 3,000 eggs during her 10 to 30-day lifespan.

When the eggs hatch into maggots, the maggots eat live tissue, causing a worsening, often painful and foul-smelling wound, according to the CDC.

Screwworm has hit the United States before

There was a screwworm outbreak in the southwestern region of the United States in 1965 that prompted Mexican and U.S. livestock producers to sign a declaration to establish a joint program for the eradication of the screwworm from the states on either side of the Mexico-U.S. border, according to the National Agricultural Library.

By 1966, the United States had eradicated screwworms, but livestock remained vulnerable to reinfestation from screwworms migrating from Mexico.

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Eradication was possible through the sterile insect technique, which uses gamma radiation to irradiate screwworm pupae and create sterile male flies.

The U.S. Department of Agriculture’s Animal and Plant Health Inspection Service maintains a screwworm pupae sterilization facility in North America and is currently building a new center in southern Texas.

When produced and released in large numbers, sterile male flies mate with wild female flies, which then lay unfertilized eggs, according to the USDA.

“Since female screwworm flies normally mate only once, the population progressively reduces and is, ultimately, eradicated,” according to USDA officials.

Last year, the Trump administration cut thousands of grants and programs from the U.S. Agency for International Development, which includes U.S.-funded animal disease monitoring projects operated by the United Nations Food and Agriculture Organization, Argi-Pulse Communications reported. Among the slashed programs were some dedicated to monitoring and containing New World screwworm in Central America.

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Today, screwworm infestations aren’t a regular occurrence in the U.S., but cases have occurred in travelers returning from areas where the flies are present, according to the CDC.

Can infected animals be treated?

Infected wounds are cleaned and debrided to remove any screwworm larvae, after which the animal is treated with an approved insecticide, DeNotta said.

Last month, the U.S. Food and Drug Administration issued an emergency use authorization for several insecticides known to be effective against screwworm.

There are approved systemic and topical options for a variety of species, including cattle, horses, small ruminants, cats and dogs, DeNotta said.

“Multiple days of treatment are often required, and antibiotics and analgesics may also be administered to treat secondary infection and control pain,” she said.

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If left untreated, the tissue destruction caused by flesh-eating larvae can be extensive and severe, often resulting in debilitation and eventual death of the host, DeNotta said.

“Animals that survive may suffer weight loss, poor growth and reduced productivity as a result of pain and discomfort,” she said.

Screwworm can infect humans

Human infection is rare, DeNotta said, but it can happen.

Humans are at risk of being infected by screwworms if they travel to an area where the flies are present, such as South America and the Caribbean, according to the CDC.

CDC officials said your risk of screwworm infection increases when you:

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  • Spend a lot of time outdoors during the day, especially if sleeping or unable to keep the flies at bay.
  • Have any open wounds. A small break in the skin, including from a scratch, insect bite or recent surgery, may attract screwworm flies.
  • Have a medical condition that causes bleeding or open sores, such as from skin or sinus cancer, or from treatments that can create breaks in the skin.
  • Live, work or spend an extended amount of time with or near, livestock or other warm-blooded animals in areas where screwworm flies are present.

The symptoms humans experience when infected by screwworm

The following are symptoms of screwworm according to the CDC:

  • Feeling maggots move or seeing maggots within a skin wound, sore or body opening.
  • Painful skin wounds or sores that worsen within a few days.
  • Foul-smelling odor from the site of the infestation.
  • Bleeding from open sores.

Bacteria can also infect wounds where screwworm maggots are present and may cause an infection that can lead to symptoms like fever or chills.

To treat a screwworm infection, DeNotta said, people undergo the same combination of wound debridement and insecticides used in animals.

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One label, many risks: how grouping Asian Americans hides deadly cancer patterns

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One label, many risks: how grouping Asian Americans hides deadly cancer patterns

California researchers are leading a nationwide effort to find out why some Asian American communities have high rates of certain cancers.

It comes as health experts see rising rates of lung cancer among Asian American women who have never smoked and increasing rates of early-onset breast cancer.

“Asian Americans are actually the first racial and ethnic group for whom cancer is the leading cause of death,” said Scarlett Gomez, a cancer epidemiologist at UC San Francisco and a lead on the project.

UCSF joins researchers from UC Irvine, UC Davis, Cedars-Sinai and Temple University in launching a $12.5 million National Cancer Institute-funded study called the ASPIRE Cohort, that will follow 20,000 Asian Americans over time. Researchers say it’s the first large-scale longitudinal cancer study focused on Asian Americans.

Lung cancer incidence has declined across much of the United States as smoking rates have fallen. However, researchers have observed a slight increase among Asian Americans, despite relatively low smoking rates, particularly among women. More than half of Asian American women diagnosed with lung cancer are nonsmokers, they say.

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Many existing studies of lung cancer risk among nonsmokers have been conducted in Asia, where exposure patterns can differ significantly from those in the United States, said Iona Cheng, a molecular epidemiologist at UCSF and also a lead on the project.

Researchers know that outdoor air pollution, secondhand smoke and cooking oil fumes can contribute to lung cancer risk. But it’s not clear if these explain disease patterns among Asian Americans in the United States.

Rising rates of breast cancer among Asian American women are also driving the push.

“Early onset breast cancer” — diagnosed before age 50 — “is going up the fastest among Asian Americans,” Gomez said. Recent data show rates among Asian Americans, Native Hawaiians and Pacific Islanders are approaching those of non-Hispanic white women, she said. Cancer experts don’t know why.

One of the central goals of the ASPIRE study is to move beyond treating Asian Americans as a single category. The term can include people with roots in dozens of countries from Sri Lanka to China’s border with Russia to Pacific islands, with completely different exposure patterns and cuisines.

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“When we separate and look at all the distinct Asian ethnicities, we see a wide variation,” Cheng said.

Filipino women have a higher incidence of thyroid cancer, and stomach cancer has been more common among some Korean and Japanese people. Combining all Asian Americans into one category can make those differences impossible to detect.

The study also seeks to address longstanding gaps in representation. Although Asian Americans make up nearly 8% of the U.S. population, they have historically received little research funding.

Existing cancer studies have also often included too few Asian Americans to draw meaningful conclusions about specific ethnic groups, researchers said. Salma Shariff-Marco, a social and behavioral scientist at UCSF and also a lead on the projects, aid that has made it hard to show the need for more targeted research. The ASPIRE cohort, she said, is designed to show the variation by including a broader range of ethnic groups and more contemporary exposures than previous work.

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