Science
Commentary: 7 million people have Alzheimer's. Why is the Trump administration derailing research?
Dr. Charles DeCarli, co-director of the UC Davis Alzheimer’s Research Center, got the news in a call from a colleague on March 24.
“Your study was terminated.”
DeCarli had been conducting a six-year examination, funded by the National Institutes of Health, of brain and vascular conditions that can be risk factors for dementia. The study, involving hundreds of medical staff, 14 research sites, and 1,700 patients at 19 clinical locations in the U.S., was building toward a goal of 2,250 patients.
Steve Lopez
Steve Lopez is a California native who has been a Los Angeles Times columnist since 2001. He has won more than a dozen national journalism awards and is a four-time Pulitzer finalist.
“This was the culmination of my career, the pinnacle of my research” over the last 38 years, DeCarli said.
The $53-million study, paid in annual allotments, was approved during President Trump’s first term. But in Term Two, the administration has taken a chain saw to universities, federal jobs and federal funding for scientific research, which has prompted talk of a brain drain, with scientists looking for work in other countries.
The termination letter from NIH informed DeCarli that his study, with its “artificial and non-scientific categories,” was on the chopping block because it “no longer effectuates agency priorities.” The UC Davis study was one of 14 such research projects notified in March that funding was being terminated.
About 7 million U.S. residents aged 65 and older have Alzheimer’s, the nation’s seventh-leading cause of death. Given the cresting age wave, the number is expected to roughly double in the next 35 years. So it doesn’t make sense that a deeper understanding of a complex set of unremittingly cruel brain diseases that decimate the lives of victims, and their loved ones, is no longer a priority.
Mannie Rezende, who was suffering from Alzheimer’s, walks with his wife Rose Shalom in June 2023. About 7 million U.S. residents age 65 and older have Alzheimer’s, the nation’s seventh-leading cause of death.
(Genaro Molina / Los Angeles Times)
DeCarli suspects he was targeted because of the name of his study:
“The Clinical Significance of Incidental White Matter Lesions on MRI Amongst a Diverse Population with Cognitive Complaints.”
DEI — diversity, equity and inclusion — programs are on the administration’s hit list. But in this case, “diverse” was a reference to a spectrum of health and age, and educational and racial backgrounds of patients.
With the help of UC Davis lawyers, DeCarli appealed the decision, but he also had to begin shutting down the study in anticipation of a second rejection or a long appeal process.
The appeal was successful, and funding was restored on April 11, but DeCarli is still playing catch-up.
“There were big-time disruptions,” he told me.
Clinical partners, who each had to contact as many as 100 patients with news of the termination, had to reach out again to tell them the green light was back on.
But for how long?
Nobody seems to know, said Russ Paulsen of UsAgainstAlzheimer’s, a nonprofit advocacy group. When I spoke to him on Wednesday, Paulsen had just watched a Senate hearing in which Appropriations Committee Chair Susan Collins (R-Maine), demanded that NIH cuts be restored.
Mannie Rezende and wife Rose Shalom with their dogs Clara, foreground, and Teddy in 2023.
(Genaro Molina / Los Angeles Times)
“I think there is broadly bipartisan support” for continued research into Alzheimer’s, Paulsen said. And the official word at Health and Human Services is that the administration remains committed to “robust biomedical research” and “maintaining our global leadership in science and technology.”
But that claim doesn’t square with the dismissal earlier this year of 1,000 NIH employees, or with news accounts of a plan to slash 30% of the Health and Human Services budget and 40% of the NIH budget.
“It’s hard to imagine somebody opposed to finding cures, and yet we have no explanation for why they’re proposing a 40% cut,” Paulsen said.
“We know that funds are flowing out the door far slower than they have in many years, and we know that researchers are submitting high-quality research and getting ‘answer pending’ or getting rejected,” he added. “And we know that existing multi-year grants are being canceled or payment is being delayed.”
In March, Rose Shalom of Sunland lost her husband, Mannie Rezende, who had slowly deteriorated from Alzheimer’s over several years. Shalom called the disruption of research egregious and immoral, and she said those who control the purse strings on research should “spend some time with someone with Alzheimer’s and their caregivers to understand the unique horror of this disease.”
I visited Rose and Mannie in 2023 at their home and at OPICA, the West L.A. adult day-care center where Mannie spent his days with a few dozen others on the same path.
“As we are living longer, more and more people will be diagnosed with this disease,” Shalom said. “The emotional and financial toll on the patients and their caregivers is beyond description.”
There is, unfortunately, no cure on the immediate horizon. But DeCarli said there have been some encouraging advances, including medication that can help slow the progression of cognitive decline, and improved diagnostics that can lead to earlier intervention.
The U.S. is both a world leader and a collaborator in medical research, DeCarli said. The process is integrated, “with people working on different parts … of the same question, and true discovery sometimes comes from interacting” with each other.
The Trump administration seems to have a different agenda.
It includes:
· Dismantling the U.S. role in solving medical mysteries.
· Dismissing hundreds of researchers studying the impact of global warming.
· Driving scientists to look for work in other countries.
Who knew there’d be so many backwater swamps, potholes and detours on the road to making America great again.
steve.lopez@latimes.com
Science
Video: NASA Announces Artemis III Crew
new video loaded: NASA Announces Artemis III Crew
transcript
transcript
NASA Announces Artemis III Crew
NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.
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“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”
By Alisa Shodiyev Kaff
June 9, 2026
Science
Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies
Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.
But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.
“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.
That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.
The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.
(RCDSMM Stream Team)
The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.
Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.
Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.
Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.
But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.
“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”
Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.
“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”
The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.
Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.
Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.
She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.
The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.
(RCDSMM Stream Team)
Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.
There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.
For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.
Science
Pacifica pier cracks, another coastal casualty as seas continue to rise
The Pacifica Municipal Pier was shut down and taped off Thursday after city workers noticed cracks running through the landmark structure and concrete chunks falling into the ocean.
It’s just one of many coastal California structures that have recently crumbled under pressure from a rising and relentless ocean.
Officials from the small, beach city south of San Francisco said the pier was closed due to “cracking, separation, and displacement of the concrete walkway and structural elements.”
It will stay closed while structural engineers asses its safety.
Photos taken by city employees show a wide crack that runs from top to bottom and across the structure as well. Other photos show a large horizontal crack under the foundation of a small restaurant on the pier, the Chit Chat Cafe.
The cafe was also shut down.
This is not the first time the 53-year-old pier has shown signs of stress. In 2021, part of it was shut down after handrails along the edge collapsed. And in 2023, after a series of storms pummeled the Central California coast, damaging parts of the pier, the structure was partially closed for more than year.
Those same storms caused extensive damage in Aptos and Capitola, 70 miles south, where piers and waterfront infrastructure were swept away or damaged.
In 2024, a 150- to 180- foot section of the Santa Cruz wharf was ripped off by powerful waves.
At least 10 of the state’s dozens of coastal public piers were closed for part or all of 2024 due to structural damage sustained in winter storms since 2022. At least five others have longer-term upgrades planned to address structural issues.
“These things are costly to maintain,” said Zach Plopper, senior environmental director at Surfrider. “They are a part of our California coastal culture in many ways, but we’re going to need to reckon with, one, the state that they’re in, and two, the continuous and worsening threats they’re going to experience,”
He said most of the piers were constructed in the early 1900s, and they weren’t built to withstand decades of rough seas, storms and rising sea level.
“With this incoming El Niño, which is forecasted to be significant, and this marine heat wave we’re in the midst of, we’re kind of in uncharted waters as far as what this winter could bring in terms of storms and swells to the California coast, and we’re likely going to see a lot more damage,” he said. “Not just piers, but roads and other coastal infrastructure up and down the state.”
There was no storm in Pacifica earlier this week, so no single event could be blamed for the destruction.
However, a 2025 report from an outside engineering firm, GHD, found that several sections of the pier were in “poor” or “serious” condition, and they recommended closure before anticipated storms or events that could “subject the piles to high winds, swells and large waves.”
The firm found several areas of the pier where concrete was missing and rebar was exposed and corroding.
“The pier has continued to experience high winds and large waves in a harsh marine environment,” the engineers wrote in the report, noting that continuous exposure to seawater or marine spray was “detrimental” to the structure.
A 2023 city report estimated it would cost $19 million to repair.
That same year, a state law was enacted to require local governments along the California coast to plan for sea level rise in the coming decades.
Sea level has risen some 8 inches, on average, along the coast in the past 150 years, Plopper said, and researchers anticipate another foot in the next 25 years.
“We’re going to see profound shifts on our coastline, none that we have ever experienced before, and building static structures on the coast just doesn’t work all that well,” he said. “We’re going to have to make some really hard decisions.”
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