Science
Scientists say they ‘de-extincted’ dire wolves. Experts at La Brea Tar Pits are skeptical
When news broke that scientists in Texas had succesfully reintroduced the long-extinct dire wolf to the modern world, more people than just “Game of Thrones” fans took notice.
Researchers at the Natural History Museum’s La Brea Tar Pits, where a wall is decorated with hundreds of dire wolf skulls, had questions.
Namely, are they really dire wolves? Turns out, it depends on how you define it.
“What they have created is basically a genetically engineered gray wolf that has been given genetic traits so they can express morphological or physical traits that more resemble dire wolves,” said Kayce Bell, a terrestrial mammal curator at the Natural History Museum. “The technology and the tools that they are developing with this work are incredible and very powerful, but the terms that are being used to discuss it, I think, are misleading.”
Earlier this week, biotechnology company Colossal Biosciences in Dallas announced they had “de-extincted” the dire wolf, sharing the news of the births of three healthy pups. Over 18 months, experts there extracted and sequenced ancient DNA from two dire wolf fossils — a 13,000-year-old tooth from Sheridan Pit, Ohio, and a 72,000-year-old inner ear bone from American Falls, Idaho. With that ancient DNA, scientists identified gene variants specific to dire wolves and then performed multiplex gene editing with a genome from the gray wolf, dire wolves’ closest living relatives. They used domestic dogs as surrogate mothers to birth the three pups.
This undated photo provided by Colossal Biosciences shows two pups that were genetically engineered with similarities to the extinct dire wolf.
(Colossal Biosciences via Associated Press)
Colossal’s chief science officer, Beth Shapiro, said she understands the scientific skepticism that came with the announcement.
“I get it,” she said. “It’s frustrating when you work in paleontology and you feel like it’s not effective science communication, and I wish I’d done a bit better.”
Though Southern California has a jackpot of dire wolf fossils relative to other sites, extracting DNA from the local samples is difficult. Shapiro said she’s been trying and unable to collect DNA from local samples for 20 years. Among the reasons it’s challenging to collect, experts say, is that L.A.’s urban landscape bakes in the sun, heating up the asphalt, which could degrade ancient DNA buried underneath.
La Brea Tar Pits has the highest concentration of dire wolf fossils in the world, with remains from over 4,000 dire wolves found at the site. They lived in the region for at least 50,000 years, disappearing about 13,000 years ago.
“There’s no other site on Earth that even comes close to that,” said Emily Lindsey, the associate curator and excavation site director at La Brea Tar Pits.
Dire wolves, native to Southern California but not limited to the region, were highly adaptable and had a very wide range of environmental tolerances before the species went extinct about 10,000 years ago, Lindsey said.
The three pups — Romulus and Remus, who were born in October, and Khaleesi, born in January — now live on an ecological preserve at an undisclosed location that spans over 2,000 acres and hosts 10 full-time staff members who care for and observe them. The preserve is certified by the American Humane Society and registered with the U.S. Department of Agriculture.
Depending on how you look at it, that could be dire wolf territory now.
In 2016, the International Union for Conservation of Nature published a report that focused on de-extinction and defined it as “bringing back a proxy of an extinct species that resembles it in some way, phenotypically, physiologically, ecologically,” Shapiro said.
But in the end, she said she’s not really hung up on what the animals are called beyond their names, inspired by founders of Rome and the “Game of Thrones” show.
“Call it a de-extinct dire wolf that abides by the definition that the scientific community agreed on 10 years ago. Call it Colossal’s dire wolf. Call it a gray wolf with 20 edits that looks and acts like a dire wolf and is a functional replacement for a dire wolf,” Shapiro said.
Part of Colossal’s announcement this week included news that they had also successfully created four clones of the endangered red wolf using a new noninvasive cloning technology. Both Lindsey and Bell said they appreciated Colossal’s work on conserving endangered species, but think that focusing on conservation is a more productive use of resources.
“There are potentially useful applications of some of these technologies, particularly for preventing highly endangered species from going extinct. I think that would be a far more efficient application of these technologies than trying to bring something resembling an extinct species back to life,” Lindsey said. “I’d hate to have to be trying to de-extinct wolves once they go extinct, right?”
Colossal’s Chief Executive Ben Lamm said the company wants to pair their “de-extinction events” with work they’re doing to protect critically endangered species. The company’s other de-extinction hopes include reviving the woolly mammoth, the dodo, and the thylacine, or Tasmanian tiger. To Lamm and Shapiro, de-extinction and conservation can work in tandem.
“Conservation and de-extinction are not at odds with each other. The de-extinction toolkit should be part of the increasing number of ways that we have at our fingertips to be able to help endangered species survive,” Shapiro said.
Lamm, who held up drawings of dodos and other extinct animals children had sent to the Colossal team during a Zoom interview with The Times, said he thinks the milestone could also inspire more people to pursue careers in related fields.
“The world needs a little hope right now, and I think the world needs more science. Hopefully, we’re providing a little bit of both,” he said.
And yes, of course “Jurassic Park” quotes and references are tossed Lamm and Shapiro’s way with stunning frequency.
“People actually say to us, ‘Don’t you know what happened in Jurassic Park?,’ equating it to, like, Chernobyl,” Lamm said. “ ‘Didn’t you see what happened there?’ Not, ‘Didn’t you watch the movie and learn anything about human hubris from the movie?’ They don’t say that.”
Shapiro added: “People are yelling at us that these aren’t real dire wolves. But no one has ever questioned whether the dinosaurs in ‘Jurassic Park’ are real dinosaurs.”
While the debate is still open, Lindsey said she invites anyone curious about the creatures to visit La Brea Tar Pits to see some of the “real dire wolves” that they have excavated at the site.
“It’s a really cool opportunity — one that you don’t get in almost any other city in the world — to come and really see the incredible diversity of large animals that lived here until very recently,” Lindsey said.
Science
Why new dads shouldn’t panic about low testosterone
Three months after his son was born, Kevin Maguire felt alone.
It was 2019. He had recently moved to Barcelona with his wife and daughter and was working on marketing projects for Fortune 500 companies. The birth of his son, Bodhi, should have been a joyous event. But Maguire, now 43, became sad and irritable, and didn’t want to be around his newborn. He withdrew from family and friends, often playing video games late into the night or finding excuses to get out of the house.
“I would take the dog out for a walk,” Maguire said. “I wanted to get far away enough that I wouldn’t bump into anyone I knew and I would just sit and cry.”
Desperate for answers, he entered his symptoms online. Maguire, author of the recently published book “The New Fatherhood: Why Everything They Told You About Being a Dad Is Wrong, and How Embracing It Will Transform Your Life,” knew to look for signs of the “baby blues” in his wife. But he was surprised by articles that said men could experience postpartum depression too. The diagnosis resonated and he began writing about his condition and the trials of fatherhood on Substack.
New dads face psychological pressures, from sleepless nights to sky-high bills, which can contribute to postpartum depression. So can shifting hormone levels.
“One thing I found in my lab’s research is that when new dads have really low levels of testosterone, they might report more symptoms of postpartum depression,” said Darby Saxbe, a professor of psychology at USC and author of the recently published “Dad Brain: The New Science of Fatherhood and How It Shapes Men’s Lives.”
While hormonal shifts can create challenges, they also help men adapt to fatherhood, Saxbe explained. Several hormones can spike in men when they become dads, including oxytocin, linked to better relationship quality; vasopressin, associated with emotional bonding; and prolactin, which promotes lactation in women and caregiving behavior in guys.
New dads can also experience a decline in testosterone. According to a 2011 paper from University of Notre Dame professor Lee Gettler, part of the largest study on fatherhood and testosterone ever conducted, men averaged around a 25% drop in testosterone after becoming fathers.
While dads have reasons to be concerned by plummeting levels of testosterone, a modest dip isn’t necessarily a disaster — in fact, it can make men better parents and partners.
“We often get invested in the idea that men should always have the highest possible levels of testosterone,” Saxbe said. “What the research tells us is a little more nuanced. You really want flexibility. You want a hormonal system that can adapt to the different demands of your life.”
The prospect of a decline might scare soon-to-be fathers, especially those on TikTok and Instagram, where accounts push the idea that having “high T” is the key to being a “real man,” according to a recent study in the journal Social Science & Medicine.
Influencers stand to profit persuading men there’s a widespread “masculinity crisis,” the researchers found, noting that 72% of the accounts they analyzed had a stake in testosterone supplements and treatments.
But studies show more testosterone isn’t always better. “We found that when dads have higher testosterone, even before birth, they’re less invested [than men with lower testosterone] in co-parenting a few months after birth,” Saxbe said. High T fathers were more stressed from parenting than their lower T counterparts, and had partners who were less satisfied in their romantic relationships.
This jibes with the challenge hypothesis, which says, in multiple species, testosterone levels rise when males battle for attention from potential mates and go down when it’s time to take care of the young.
While a small decline can be adaptive, dads face mental health risks when their testosterone drops too low.
There is no “normal” level of testosterone, said Dr. Jesse Mills, director of the Men’s Clinic at UCLA Health. Experts recommend that men should consider treatment if their levels dip below 300 nanograms per deciliter (ng/dL). But men metabolize testosterone in different ways, meaning a healthy level for one might be low for another.
“If a new dad comes to me and his testosterone is 298 [ng/dL], he’s below the threshold,” Mills said. “But if he has zero symptoms and everything else is going great — he’s over the moon with his new child, he’s so happy — that’s not somebody I’m going to treat with testosterone.”
He notes that the drop in testosterone fathers experience can partly be attributed to the stresses that come with a new kid: less sleep, a poor diet and fewer trips to the gym. That means there are precautions that expectant fathers can take that don’t involve testosterone replacement therapy (TRT).
Still, while some guys with low testosterone levels might not need TRT, others in the “normal” range could benefit from treatment. (Dads who want another kid soon, beware. Mills notes that testosterone replacement therapy can take a man’s sperm count to zero.)
Both Mills and Saxbe stress that men should be paying attention to symptoms of low testosterone — such as depression and low libido — rather than trying to reach or maintain an ideal number. They also agree that tending to mental health concerns is hugely important for new fathers.
Eventually, after Maguire researched his condition, he recovered after time spent meditating, exercising and bonding with his son.
“A lot of new dads don’t realize how much they’re struggling because they feel ashamed or because they don’t realize it’s common shortly after the birth of a baby,” Saxbe said.
When they struggle, fathers can fixate on testosterone because that’s what modern culture tells them will make them feel better. And sometimes testosterone replacement therapy works. But Saxbe stresses a lot of men could use psychotherapy or support groups that bring dads together, as well as more time bonding with loved ones in general.
“The thing that predicts a man’s well-being and longevity is the quality of his relationships with other people,” said Saxbe. “You can be the world’s best weightlifter. You can have a low body-fat percentage. You can be killing it at work. Those things don’t predict how happy you’re going to be at 80.”
Science
Video: NASA Announces Artemis III Crew
new video loaded: NASA Announces Artemis III Crew
transcript
transcript
NASA Announces Artemis III Crew
NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.
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“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”
By Alisa Shodiyev Kaff
June 9, 2026
Science
Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies
Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.
But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.
“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.
That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.
The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.
(RCDSMM Stream Team)
The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.
Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.
Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.
Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.
But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.
“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”
Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.
“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”
The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.
Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.
Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.
She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.
The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.
(RCDSMM Stream Team)
Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.
There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.
For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.
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