Health
Cervical cancer deaths could be reduced with home HPV testing, study finds
A push for more accessible HPV testing is underway.
A new program called SHIP Trial Network, led by the National Cancer Institute (NCI), is exploring testing for human papillomavirus (HPV) via self-collection to prevent cervical cancer, according to a press release.
The Last Mile Initiative, announced at the White House Cervical Cancer Forum on Jan. 25 by NCI’s director Dr. Kimryn Rathmell, will gather data on a self-collection method for HPV.
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HPV testing can be crucial for preventing cervical cancer, according to Dr. Brian Slomovitz, director of gynecologic oncology and co-chair of the Cancer Research Committee at Mount Sinai Medical Center in Miami Beach, Florida.
Slomovitz advocated for this self-collection method in an interview with Fox News Digital.
SHIP Trial Network stands for “Self-collection for HPV testing to Improve cervical cancer Preventions.” Screening, said one doctor, “is of the utmost importance.” (iStock)
More than 50% of individuals in the U.S. who have developed cervical cancer have never been or are infrequently screened, according to Slomovitz and NCI.
“We know that screening is of the utmost importance,” he said.
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Nicole B. Saphier, M.D. — associate professor at Memorial Sloan Kettering Cancer Center in New York City, director of breast imaging at Memorial Sloan Kettering in Monmouth, New Jersey, and a Fox News medical contributor — reiterated the importance of routine screening for cervical cancer.
“While it’s not practical to screen for all cancers, cervical cancer is certainly one that benefits from routine screening,” she told Fox News Digital.
Nearly 100% (99.7%) of cervical cancers are caused by an HPV infection, according to Saphier.
Many patients are turned off by the “intrusiveness” of pap smears, said one physician. (iStock)
Since pap smears began screening for HPV by taking a sample of the cervix, Saphier noted that cervical cancer mortality has decreased.
One of the limitations of screenings, according to Slomovitz, is a lack of access to providers due to proximity, financial restrictions or other factors.
“Bottom line, anything that works for early cancer detection is important.”
“One of the advantages of at-home testing is that, in essence, it could eliminate a lot of these barriers,” he said.
“Some women may have a job during the week, and they don’t have the time to go to a doctor’s office, or some people don’t have the money to pay for the visit.”
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Saphier added that many women avoid regular cervical cancer screenings due to the “intrusiveness of the exam,” similar to colon cancer screenings and colonoscopies.
“As such, colon cancer screening[s] with at-home tests have increased colon cancer screening,” Saphier said.
Nearly 100% (99.7%) of cervical cancers are caused by an HPV infection. (iStock)
“The SHIP trial initiative for patients to screen themselves at home for HPV is important, so it can give patients who otherwise would not be screened an option for at-home screening.”
By offering at-home testing, providers are “recognizing the importance of cervical cancer screening, but we’re doing it in such a way that makes it a lot easier for the patients,” Slomovitz noted.
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The HPV self-collection, which would come in the form of a vaginal swab, would help identify those women who require an in-office follow-up with a doctor, he said.
Although the swab would have to be sent to a lab for results — requiring an extra step compared to other at-home tests — Slomovitz believes it would still be a popular alternative for patients.
An at-home HPV sample collection would “eliminate a lot of the barriers” that bar patients from being screened at a doctor’s office, an expert said. (iStock)
“The time it takes to go to the doctor’s office and the expense are sometimes prohibitive for the entire population,” he said. “So even with the extra step of mailing it in, this is going to be a lot easier than having to go to the doctor’s office.”
Saphier said her concern about self-collection is that patients “won’t get adequate samples and the test may result in a false negative.”
She added, “Bottom line, anything that works for early cancer detection is important, in my opinion.”
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“But these at-home tests should be taken with precaution, as they are unlikely to be as sensitive and specific as the gold-standard tests for cancer detection.”
While the test itself isn’t yet ready for “prime time,” Slomovitz pointed out that the SHIP Network is backed by the government and on the road to potential FDA approval.
HPV is “highly preventable” by HPV vaccination and by early detection and treatment of “cervical precancerous changes,” according to NCI. (iStock)
“The best way to treat cancer is to prevent cancer,” he said. “And something like this is definitely a huge step in further prevention.”
NCI reiterated in its press release that HPV is “highly preventable” by HPV vaccination, early detection and treatment of “cervical precancerous changes.”
“These at-home tests should be taken with precaution, as they are unlikely to be as sensitive and specific as the gold-standard tests.”
The NCI has partnered with professional societies to revise and update guidelines for health care workers to integrate self-collection approaches into their clinical practice once the method has been approved, the group wrote.
“In addition, NCI is developing a publicly accessible repository of self-collection instructions and educational materials for clinicians, community health workers and people who may use the testing method in the future,” they added.
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Health
Loneliness may be silently eroding your memory, new research reveals
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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
Health
Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day
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Health
Intermittent fasting’s real benefit may come after you start eating again
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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