The Seattle Seahawks (4-5) are on the road in Week 11 taking on the San Francisco 49ers (5-4). Kickoff from Levi’s Stadium is Sunday at 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Seahawks vs. 49ers odds, and make our expert NFL picks and predictions.
The Seahawks, coming off their bye, have lost 2 straight games and 5 of their last 6 after a 3-0 start to the season. Their last game was a 26-20 overtime home loss to the LA Rams as 1-point underdogs.
The 49ers have won 2 in a row. They beat the Tampa Bay Buccaneers 23-20 on the road last week on a last-second field goal by K Jake Moody. They failed to cover the 6.5-point spread as favorites.
The 49ers won the first meeting this year 36-24 in Seattle in Week 6.
Play our free daily Pick’em Challenge and win! Play now!
Seahawks at 49ers odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 12:21 a.m. ET.
- Moneyline (ML): Seahawks +240 (bet $100 to win $240) | 49ers -300 (bet $300 to win $100)
- Against the spread (ATS): Seahawks +6.5 (-110) | 49ers -6.5 (-110)
- Over/Under (O/U): 48 (O: -110 | U: -110)
WIN YOUR FANTASY FOOTBALL LEAGUE!
The Huddle has been turning players like you into winners for over 25 years. This season, it’s your turn. Custom fantasy football rankings, sleepers and tools are just a click away. Save 25% off the Internet’s best-kept secret. Subscribe now!
Seahawks at 49ers key injuries
Seahawks
- TE Noah Fant (groin) out
- TE Brady Russell (foot) out
- C Connor Williams (personal – announced retirement) out
49ers
- OL Aaron Banks (thigh) questionable
- DE Nick Bosa (hip) questionable
- DT Kevin Givens (groin) out
- OL Jon Feliciano (knee) questionable
- DE Yetur Gross-Matos (knee) questionable
- CB Darrell Luter (pelvis) doubtful
- TE George Kittle (hamstring) questionable
- CB Charvarius Ward (personal) out
- OL Trent Williams (ankle) questionable
- P Mitch Wishnowsky (back) out
FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+
Seahawks at 49ers picks and predictions
Prediction
49ers 27, Seahawks 23
Moneyline
Seattle has allowed 29.7 points per game in the 6 games after their 3-0 start while San Francisco has allowed between 20 and 28 points in each of their last 5 games.
The Niners have beaten the Seahawks in 6 straight games. San Fran can tie the idle Arizona Cardinals atop the NFC West with a win. They should pick up the win,, even though they are banged up, but -300 odds aren’t worth the action.
PASS.
Against the spread
The 49ers are 5-1 ATS in their last 6 games against Seattle, but their wins in the last 2 games have not been by more than 6 points.
Four of Seattle’s losses this season have been by more than 6 points, but with so many injuries for the Niners, this will stay close.
BET SEAHAWKS +6.5 (-110).
Over/Under
Their first meeting had 60 total points, but only 2 of the last 6 games for the Niners have surpassed 48. None of the last 3 games for the Seahawks have topped 48.
But with the Seahawks allowing nearly 30 points per game in the last 6 contests and San Francisco’s opponents averaging 24 over the last 5, expect some points.
BET OVER 48 (-110).
Want to play some games of your own? Play for free at the best social casinos and enjoy lots of slots, blackjack, video poker, roulette and more. You can even earn real prizes!
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.
Access more NFL coverage:
BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire