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San Francisco 49ers at Jacksonville Jaguars: Predictions, picks and odds for NFL Week 10 game

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San Francisco 49ers at Jacksonville Jaguars: Predictions, picks and odds for NFL Week 10 game


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Could this be a possible Super Bowl matchup?

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Teams hanging around the top of their conference will meet in a juicy matchup when the San Francisco 49ers (5-3) head East to face the Jacksonville Jaguars (6-2).

A bye week came at the perfect time for the 49ers, as they’ve seen their 5-0 start turn into a three-game losing skid. But things may be turning around, thanks to general manager pulling off a big win at the trade deadline by getting Chase Young to bolster what already has been a top of the NFL defense. If Brock Purdy can get back into his 2022-self, San Francisco can quickly get back into the Super Bowl picture.

Another team coming off a bye, Jacksonville is showing the promise of their young squad with a five-game winning streak that puts them near the top of the AFC. All sides of the ball have been on point, as the Jaguars are poised to win another division title and be a serious contender in the playoffs.

PROP TALK: These are the best prop bets for NFL games this week 

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Jaguars vs. 49ers odds, moneyline, over/under

The 49ers are favorites to defeat the Jaguars, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

  • Spread: 49ers (-3)
  • Moneyline: 49ers (-165); Jaguars (+140)
  • Over/under: 45

Not interested in this game? Our guide to the NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.

If you’re new to sports betting, don’t worry. We have tips for beginners on how to place bet online. And USA TODAY readers can claim exclusive promos and bonus codes with the online sportsbooks and sports betting sites.

MOST VALUABLE BET: These are the best NFL MVP betting odds 

NFL Week 10 odds, predictions and picks

Bears vs. Panthers | Patriots vs. Colts | Ravens vs. Browns | Bengals vs. Texans | Jaguars vs. 49ers | Vikings vs. Saints | Steelers vs. Packers | Buccaneers vs. Titans | Cardinals vs. Falcons | Chargers vs. Lions | Cowboys vs. Giants | Seahawks vs. Commanders | Raiders vs. Jets | Bills vs. Broncos

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Lorenzo Reyes: 49ers 25, Jaguars 20

This is a really difficult game to call because the 49ers have been in a slump and have also been dealing with injuries. If Deebo Samuel and Trent Williams  can return, San Francisco becomes really tough to beat. Both teams are coming off a bye, but I trust Kyle Shanahan and his staff a little more to have a calculated game plan. The Niners are weak in the secondary, however, and Trevor Lawrence can exploit that. Honestly, I can see this one going either way.

Tyler Dragon: 49ers 24, Jaguars 20

No team needed a Week 9 bye more than the 49ers, losers of three in a row. Deebo Samuel and Trent Williams are tracking to play. Plus, the 49ers front seven added another stud in Chase Young. Playing on the road in Jacksonville will be difficult but San Francisco bounces back this week. 

Safid Deen: Jaguars 34, 49ers 30

It might sound crazy picking the 49ers to lose their fourth straight game. But the Jaguars are not a team that should be overlooked. Travis Etienne might be the second-best running back in the league behind Christian McCaffrey, and the Jaguars offense can light it up with the best of them. The 49ers should get Deebo Samuel and Trent Williams back, but the Jaguars defense will slow Brock Purdy down. Jacksonville makes a statement at home over San Francisco this week.

Victoria Hernandez: 49ers 24, Jaguars 23

Both teams will feel refreshed after their bye weeks, but the 49ers have more to play for to stop a three-game skid after starting the season 5-0 and Trevor Lawrence might still be hobbled by a knee injury. The addition and enthusiasm of Chase Young should help recharge San Francisco’s defense and if they get Deebo Samuel back, that’s an added bonus.

Jordan Mendoza: 49ers 29, Jaguars 26

Both squads were headed in opposite directions going into their bye week. Jacksonville has scored at least 20 points during it winning streak, while San Francisco has scored 17 points in each loss. the Jacksonville offense will continue to score, but San Francisco turns it around with a much better offensive performance in what should be a game that comes down to the final minutes.

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You can view the full list of USA TODAY’s NFL expert predictions here.

EYE ON THE FUTURE: These are the most popular NFL future bets in 2023 

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San Francisco, CA

Thairo Estrada's go-ahead 3-run homer in the fifth inning lifts Giants past Rockies 10-5

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Thairo Estrada's go-ahead 3-run homer in the fifth inning lifts Giants past Rockies 10-5


SAN FRANCISCO (AP) — Thairo Estrada hit a go-ahead three-run homer in the fifth inning and singled twice, Luis Matos drove in a career-high five runs and the San Francisco Giants beat the Colorado Rockies 10-5 on Friday night for their sixth straight victory at home in the series.

Matos and Matt Chapman had three hits apiece for a refreshed San Francisco squad coming off its first off day following 16 straight games.

Estrada’s drive to left for his seventh home run of the year chased Colorado right-hander Ryan Feltner (1-4), who gave way to Victor Vodnik. Luis Matos added a key RBI single in the inning for insurance — which mattered when Ezequiel Tovar doubled home a run in the top of the sixth before the Giants added on late.

Matos, who got the Giants going on an RBI double in the fourth, then added an RBI groundout on a bunt in the seventh before Marco Luciano singled two batters later for his first career RBI. Matos capped his outstanding night with a two-run double in the eighth.

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This was an especially tough day for the Giants, who learned earlier in the day that rookie center fielder Jung Hoo Lee needs season-ending surgery on his dislocated left shoulder that he injured crashing into the outfield wall.

Still, it was a festive spring evening as former Giants lefty 80-year-old Masanori Murakami threw out the ceremonial first pitch on Japanese Heritage Night. He sported a black Giants jacket signed by former teammates Willie Mays and the late Willie McCovey.

Jordan Beck homered in the second inning for Colorado and Ryan McMahon had a two-run double in the first as the Rockies began the game with four straight hits — including three consecutive doubles — off rookie right-hander Mason Black.

Black was recalled from Triple-A Sacramento to make his third career start still seeking his first major league victory. His night ended after he hit Jacob Stallings with a pitch to start the fourth.

Sean Hjelle (1-1) relieved and pitched two innings for the win.

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Even trailing by three after the first half-inning, the Giants continued to pound the Rockies pitchers.

TRAINER’S ROOM

Rockies: OF Nolan Jones and INF/OF Kris Bryant, both sidelined with strained lower backs, will play three straight days with Triple-A Albuquerque and are likely to join the Rockies in Oakland on Tuesday. … C Elias Diaz, who exited Tuesday’s game at San Diego in the third inning with a sore left hand, isn’t expected to need a stint on the IL and is getting treatment for the injury.

Giants: RHP Keaton Winn was placed on the 15-day injured list retroactive to Wednesday with a strained pitching forearm. … OF Jorge Soler returned from his rehab assignment and was reinstated from the 10-day IL and played designated hitter batting leadoff, while INF Casey Schmitt was optioned to Sacramento.

CASALI’S RETURN

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Curt Casali, who signed a one-year contract Wednesday to rejoin the Giants, can earn $1 million while in majors and $150,000 while in minors.

UP NEXT

LHP Ty Blach (1-1, 3.00 ERA) pitches the middle game for the Rockies against his former club and LHP Kyle Harrison (3-1, 3.42) takes the mound for San Francisco.



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Insider Says Former San Francisco Giants Top Prospect Could Be Emerging Star

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Insider Says Former San Francisco Giants Top Prospect Could Be Emerging Star


The San Francisco Giants begin their three-game weekend series against the surging Colorado Rockies on Friday in what is viewed as an important slate for both teams.

After being a complete disaster to start the year, the Rockies are now 7-3 in their last 10 games and seemed to have found a bit of a groove.

The Giants, on the other hand, are still struggling to put together consistent performances and are dealing with a litany of injuries to their projected impact players.

San Francisco needs someone to step up while Jorge Soler, Jung Hoo Lee, and Michael Conforto are sidelined on the injured list.

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They turned to one of their former top prospects, Heliot Ramos, to do so with the hopes that the extended reps he got facing Triple-A competition the past three years would better prepare him for his time in the Majors.

So far, that seems to be the case.

Ramos has gone 9-29 with two doubles and five RBI in the eight games since getting promoted.

This has prompted Alex Pavlovic of NBC Sports Bay Area to say he could become the player that sparks a turnaround for the Giants as they search for any offensive production to help them start stringing together wins.

“Heliot Ramos has a different look about him. I don’t know if it’s because he’s older. I don’t know if it’s just because he went through it, ‘this is my time’ … just has a different look about him and I’ve noticed that and I know some Giants people have noticed that. Just exudes confidence right now,” he said on “Giants Talk.”

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That would certainly be welcome for both parties.

The 24-year-old was taken with their 19th overall pick in 2017 and was expected to be a future star in their outfield.

It hasn’t quite worked out that way since he was first called up for his debut in 2022 as he struggled offensively to the point he was only used in emergency situations while primarily staying down in the minors.

But with all the injuries to San Francisco’s outfield, he is now getting another opportunity, and right now, he’s taking this chance and running with it.



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Black Restaurant Week kicks off in San Francisco Bay Area

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Black Restaurant Week kicks off in San Francisco Bay Area


FILE ART: Photo by Brett Coomer/Houston Chronicle via Getty images

Black Restaurant Week kicks off in the San Francisco Bay Area on Friday, and minority-owned business leaders are hoping for an uptick in customers as they highlight their array of rich cuisine. 

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This is the fourth year of the campaign, which ends on May 26. 

Founded in 2016 by Warren Luckett, based in Atlanta, and managed by partners Falayn Ferrell and Derek Robinson, based in Houston, Black Restaurant Week LLC is responsible for celebrating the flavors of African American, African and Caribbean cuisine with a series of regional cultural weeks per market. To date, Black Restaurant Week has expanded to more than 15 markets including Toronto.

Black Restaurant Week

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Participating restaurants in Oakland, Emeryville and San Francisco: 

Oakland

AFRICAN:

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Jollof Kitchen, 484 Lake Park Avenue

CARIBBEAN: 

Sweet Fingers, 5859 Foothill Blvd. Suite 1

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Cocbreeze Caribbean Restaurant and Vegan Bakery, 2370 High Street

Calabash Restaurant & Market, 2300 Valdez Street

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ITALIAN: 

Marzano, 4214 Park Blvd. 

SOUTHERN:

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Fowl & Fare

101 Broadway 

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Emeryville

SOUL FOOD: 

Rob Ben’s Restaurant & Lounge, 3617 San Pablo Avenue

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San Francisco 

SOUL FOOD: 

Gumbo Social, 5176 3rd St

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SOUTHERN: 

Tastebuds, 600 5th Ave.

CREOLE & CAJUN:

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Voodoo Love, 303 2nd Street

AMERICAN:

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Rome’s Kitchen 
 



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