Arizona
Arizona Cardinals vs Jacksonville Jaguars live updates, score for NFL Week 12 game Sunday
Arizona Cardinals commit 17 penalties in loss to 49ers
Theo Mackie and Bob McManaman discuss the Arizona Cardinals’ 41-22 loss to the San Francisco 49ers at State Farm Stadium on Nov. 16, 2025.
The Arizona Cardinals continue their 2025 NFL regular season schedule with an NFL Week 12 game against the Jacksonville Jaguars today.
The Cardinals are coming off a 41-22 loss against the San Francisco 49ers in their NFL Week 11 game.
The Jaguars beat the Los Angeles Chargers in the 11th week of the season, 35-6.
This is the first game between Arizona and Jacksonville Jaguars since 2021, when the Cardinals defeated the Jaguars in Jacksonville, 31-19.
Follow our live updates of the game, which is being played at the Cardinals’ State Farm Stadium in Glendale, Arizona, for the latest score, news, notes and analysis of the Week 12 NFL game on Sunday, Nov. 23.
Watch Jaguars at Cardinals with FUBO (free trial)
Cardinals vs Jaguars schedule: What time is NFL Week 12 game?
The NFL Week 12 game between the Cardinals and Jaguars is on Sunday, Nov. 23, at 2:05 p.m. MST, 4:05 p.m. ET.
Jaguars vs Cardinals TV: What channel is NFL Week 12 game on?
The Jaguars vs Cardinals NFL Week 12 game can be seen on CBS.
Cardinals vs Jaguars streaming: How do I watch NFL Week 12 game on livestream?
Streaming options for the Cardinals vs Jaguars game include FUBO, which offers a free trial, and other streaming services that carry CBS, like Paramount+.
Jaguars vs Cardinals announcers: Who is calling the NFL Week 12 game?
Spero Dedes (play-by-play) and Adam Archuleta (analyst) are scheduled to be the announcers for the Cardinals-Jaguars Week 12 NFL game.
Cardinals vs Jaguars game odds: Who is favored in NFL Week 12?
The Jaguars are a 2.5-point favorite over the Cardinals in NFL Week 12 odds for the game, courtesy of BetMGM Sportsbook.
Jacksonville is -145 on the moneyline, while Arizona is +120.
The over/under (point total) is set at 47.5 points.
Jaguars vs Cardinals picks, predictions: Who will win NFL Week 12 game?
The Arizona Republic’s Jeremy Cluff is predicting a 24-20 win for the Jaguars over the Cardinals in the Week 12 NFL game today.
Other sites lean toward the Jaguars beating the Cardinals in their NFL Week 12 picks and NFL Week 12 predictions for the game, but not everyone is taking Jacksonville to cover the point spread.
Pregame reading for Cardinals vs Jaguars Week 12 NFL game today
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