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Arizona basketball March Madness prediction: How far will Wildcats go in NCAA Tournament?

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The NCAA Tournament bracket is set. How hard is the Arizona Wildcats’ potential road to the Final Four?

Here’s a look at Arizona’s possible opponents in each round of March Madness and our prediction for how far Tommy Lloyd’s team will advance in the bracket.

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Last season, Arizona advanced to the Sweet 16 as a No. 2 seed, beating No. 15 Long Beach State 85-65 in the first round and No. 7 seed Dayton 78-68 in the second round before falling to No. 6 seed Clemson, 77-72.

The Wildcats haven’t made the Elite Eight since 2015. They haven’t made the Final Four since they lost to Duke in the 2001 National Championship game.

Could they end those skids in the 2025 NCAA Tournament?

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Arizona’s first-round NCAA Tournament opponent

Tommy Lloyd’s team is the No. 4 seed in the East Region of March Madness and will face No. 13 seed Akron in the first round of the NCAA Tournament in Seattle, looking to begin a long NCAA Tournament run.

Arizona’s first-round March Madness opponent, Akron, advanced to the NCAA Tournament by winning the MAC Conference Tournament.

It went 28-6 overall in the regular this season and 17-1 in conference play.

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Arizona’s potential second-round March Madness opponents

The winner of the Arizona vs Akron game will face the winner of the No. 5 Oregon vs No. 12 Liberty game in the second round on Sunday, with the winner of that game advancing to the Sweet 16.

Arizona’s potential Sweet 16 opponents

Arizona would likely face No. 1 seed Duke, No. 8 seed Mississippi State or No. 9 seed Baylor in the Sweet 16, if it were to win its first two games in March Madness.

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Arizona’s potential Elite 8 opponents

If Arizona were to win its first three games, the Wildcats would face the winner of the other half of the NCAA bracket for the East Region in the regional semifinal, with No. 2 Alabama, No. 3 Wisconsin, No. 6 BYU and No. 7 St. Mary’s being the highest seeds on that side of the bracket.

Arizona’s potential Final Four opponents

The winner of the East Region faces the winner of the Midwest Region in the Final Four. If Arizona were to somehow make it that far, the highest seeds in the Midwest Region include No. 1 seed Houston, No. 2 seed Tennessee, No. 3 seed Kentucky and No. 4 seed Purdue.

Arizona’s potential National Championship game opponents

The winner of the Midwest Region vs East Region national semifinal would face the winner of the South Region vs West Region national semifinal in the NCAA title game. Arizona’s possible opponents in that game, should it somehow make a run in the tournament and advance that far?

Auburn is the top seed in the South, with Michigan State the No. 2 seed, Iowa State the third seed and Texas A&M the fourth seed. The West Region’s Top 4 seeds are No. 1 Florida, No. 2 St. Johns, No. 3 Texas Tech and No. 4 Maryland.

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Arizona Wildcats NCAA Tournament March Madness prediction

We wrote about Arizona’s “potential” opponents in the March Madness bracket, but how far will the Wildcats actually advance in the NCAA Tournament?

We predicted an 85-78 win for Arizona over Akron in our first-round March Madness game prediction. As for the second round? We think the Wildcats can get past Oregon (or Liberty) to make their second straight Sweet 16 appearance under Tommy Lloyd.

But we don’t foresee Arizona getting to the Elite Eight for the first time since 2015 in this tournament. Duke will be too much for the Wildcats in that round, even if Cooper Flagg isn’t 100%.

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Prediction: Arizona Wildcats lose in Sweet 16 of NCAA Tournament

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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